Wiebke Möbius

Survival of adult neurons lacking cholesterol synthesis in vivo (2007)

Fünfschilling, Ursula, Saher, Gesine, Xiao, Le, Möbius, Wiebke, Nave, Klaus-Armin

Abstract Background Cholesterol, an essential component of all mammalian plasma membranes, is highly enriched in the brain. Both during development and in the adult, brain cholesterol is derived from...

Modulation of Cellular Cholesterol Transport and Homeostasis by Rab11

Hölttä-Vuori, Maarit, Tanhuanpää, Kimmo, Möbius, Wiebke, Somerharju, Pentti, Ikonen, Elina

To analyze the contribution of vesicular trafficking pathways in cellular cholesterol transport we examined the effects of selected endosomal Rab proteins on cholesterol distribution by filipin...

γ-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking

Neubrand, Veronika E, Will, Rainer D, Möbius, Wiebke, Poustka, Annemarie, Wiemann, Stefan, Schu, Peter, ...

A novel peripheral membrane protein (2c18) that interacts directly with the gamma ‘ear' domain of the adaptor protein complex 1 (AP-1) in vitro and in vivo is described. Ultrastructural analysis...

Modulation of Cellular Cholesterol Transport and Homeostasis by Rab11

Hölttä-Vuori, Maarit, Tanhuanpää, Kimmo, Möbius, Wiebke, Somerharju, Pentti, Ikonen, Elina

To analyze the contribution of vesicular trafficking pathways in cellular cholesterol transport we examined the effects of selected endosomal Rab proteins on cholesterol distribution by filipin...

γ-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking

Neubrand, Veronika E, Will, Rainer D, Möbius, Wiebke, Poustka, Annemarie, Wiemann, Stefan, Schu, Peter, ...

A novel peripheral membrane protein (2c18) that interacts directly with the gamma ‘ear' domain of the adaptor protein complex 1 (AP-1) in vitro and in vivo is described. Ultrastructural analysis...

Myelin basic protein-dependent plasma membrane reorganization in the formation of myelin

Fitzner, Dirk, Schneider, Anja, Kippert, Angelika, Möbius, Wiebke, Willig, Katrin I, Hell, Stefan W, ...

During vertebrate development, oligodendrocytes wrap their plasma membrane around axons to produce myelin, a specialized membrane highly enriched in galactosylceramide (GalC) and cholesterol. Here,...