Willem B. van Leeuwen

Rapid Detection of Methicillin Resistance in Staphylococcus aureus Isolates by the MRSA-Screen Latex Agglutination Test

Van Leeuwen, Willem B., Van Pelt, Cindy, Luijendijk, Ad, Verbrugh, Henri A., Goessens, Wil H. F.

The slide agglutination test MRSA-Screen (Denka Seiken Co., Niigata, Japan) was compared with the mecA PCR (“gold standard”) for the detection of methicillin resistance in Staphylococcus aureus....

Multilocus Sequence Typing of Staphylococcus aureus with DNA Array Technology

Van Leeuwen, Willem B., Jay, Corinne, Snijders, Susan, Durin, Nathalia, Lacroix, Bruno, Verbrugh, Henry A., ...

A newly developed oligonucleotide array suited for multilocus sequence typing (MLST) of Staphylococcus aureus strains was analyzed with two strain collections in a two-center study. MLST allele...

Natural population dynamics and expansion of pathogenic clones of Staphylococcus aureus

Melles, Damian C., Gorkink, Raymond F.J., Boelens, Hélène A.M., Snijders, Susan V., Peeters, Justine K., Moorhouse, Michael J., ...

The population structure of Staphylococcus aureus carried by healthy humans was determined using a large strain collection of nonclinical origin (n = 829). High-throughput amplified fragment length...

Host- and Tissue-Specific Pathogenic Traits of Staphylococcus aureus

Van Leeuwen, Willem B., Melles, Damian C., Alaidan, Alwaleed, Al-Ahdal, Mohammed, Boelens, Hélène A. M., Snijders, Susan V., ...

Comparative genomics were used to assess genetic differences between Staphylococcus aureus strains derived from infected animals versus colonized or infected humans. A total of 77 veterinary isolates...

Clonal Distribution and Differential Occurrence of the Enterotoxin Gene Cluster, egc, in Carriage- versus Bacteremia-Associated Isolates of Staphylococcus aureus

Van Belkum, Alex, Melles, Damian C., Snijders, Susan V., Van Leeuwen, Willem B., Wertheim, Heiman F. L., Nouwen, Jan L., ...

The Staphylococcus aureus enterotoxin gene cluster, egc, was detected in isolates from healthy individuals and in those from patients with bacteremia. The egc genes cooccur and are slightly enriched...

Rapid Detection of Methicillin Resistance in Staphylococcus aureus Isolates by the MRSA-Screen Latex Agglutination Test

Van Leeuwen, Willem B., Van Pelt, Cindy, Luijendijk, Ad, Verbrugh, Henri A., Goessens, Wil H. F.

The slide agglutination test MRSA-Screen (Denka Seiken Co., Niigata, Japan) was compared with the mecA PCR (“gold standard”) for the detection of methicillin resistance in Staphylococcus aureus....

Multilocus Sequence Typing of Staphylococcus aureus with DNA Array Technology

Van Leeuwen, Willem B., Jay, Corinne, Snijders, Susan, Durin, Nathalia, Lacroix, Bruno, Verbrugh, Henry A., ...

A newly developed oligonucleotide array suited for multilocus sequence typing (MLST) of Staphylococcus aureus strains was analyzed with two strain collections in a two-center study. MLST allele...

Natural population dynamics and expansion of pathogenic clones of Staphylococcus aureus

Melles, Damian C., Gorkink, Raymond F.J., Boelens, Hélène A.M., Snijders, Susan V., Peeters, Justine K., Moorhouse, Michael J., ...

The population structure of Staphylococcus aureus carried by healthy humans was determined using a large strain collection of nonclinical origin (n = 829). High-throughput amplified fragment length...

Host- and Tissue-Specific Pathogenic Traits of Staphylococcus aureus

Van Leeuwen, Willem B., Melles, Damian C., Alaidan, Alwaleed, Al-Ahdal, Mohammed, Boelens, Hélène A. M., Snijders, Susan V., ...

Comparative genomics were used to assess genetic differences between Staphylococcus aureus strains derived from infected animals versus colonized or infected humans. A total of 77 veterinary isolates...

Clonal Distribution and Differential Occurrence of the Enterotoxin Gene Cluster, egc, in Carriage- versus Bacteremia-Associated Isolates of Staphylococcus aureus

Van Belkum, Alex, Melles, Damian C., Snijders, Susan V., Van Leeuwen, Willem B., Wertheim, Heiman F. L., Nouwen, Jan L., ...

The Staphylococcus aureus enterotoxin gene cluster, egc, was detected in isolates from healthy individuals and in those from patients with bacteremia. The egc genes cooccur and are slightly enriched...

Quality Control of Direct Molecular Diagnostics for Methicillin-Resistant Staphylococcus aureus▿

Van Belkum, Alex, Niesters, Hubert G. M., MacKay, William G., Van Leeuwen, Willem B.

Ten samples containing various amounts of methicillin-resistant Staphylococcus aureus (MRSA), methicillin-susceptible S. aureus, methicillin-resistant Staphylococcus epidermidis (MRSE), and...