William A. Coetzee

Publication List Details

Period

1990 - 2005

Number

19

Co-Authors

Immunolocalization of KATPchannel subunits in mouse and rat cardiac myocytes and the coronary vasculature (2005)

Morrissey, Alison, Rosner, Erika, Lanning, Jennifer, Parachuru, Lavanya, Dhar Chowdhury, Piyali, Han, Sandra, ...

Abstract Background Electrophysiological data suggest that cardiac K ATP channels consist of Kir6.2 and SUR2A subunits, but the distribution of these (and other K ATP channel subunits) is poorly...

Regulation of ATP sensitive potassium channel of isolated guinea pig ventricular myocytes by sarcolemmal monocarboxylate transport (1992)

Coetzee, William A

Objective: The aim was to describe the effects of extracellular application of monocarboxylates (pyruvate, lactate, or acetate) on current through KATP channels (iK.ATP) in isolated guinea pig...

Reperfusion damage: free radicals mediate delayed membrane changes rather than early ventricular arrhythmias (1990)

Coetzee, William A, Owen, Patricia, Dennis, Steven C, Saman, Selva, Opie, Lionel H

Study objective – The aim of the study was to reassess the role of reactive oxygen species in causing reperfusion arrhythmias, which they might do either by directly generating free oxygen radicals...

A role for frequenin, a Ca2+-binding protein, as a regulator of Kv4 K+-currents

Nakamura, Tomoe Y., Pountney, David J., Ozaita, Ander, Nandi, Sumon, Ueda, Stefanie, Rudy, Bernardo, ...

Frequenin, a Ca2+-binding protein, has previously been implicated in the regulation of neurotransmission, possibly by affecting ion channel function. Here, we provide direct evidence that frequenin...

The Phosphatidylinositol 3-Phosphate Phosphatase Myotubularin- Related Protein 6 (MTMR6) Is a Negative Regulator of the Ca2+-Activated K+ Channel KCa3.1

Srivastava, Shekhar, Li, Zhai, Lin, Lin, Liu, GongXin, Ko, Kyung, Coetzee, William A., ...

Myotubularins (MTMs) belong to a large subfamily of phosphatases that dephosphorylate the 3′ position of phosphatidylinositol 3-phosphate [PI(3)P] and PI(3,5)P2. MTM1 is mutated in X-linked...

Phosphatidylinositol 3-Phosphate Indirectly Activates KCa3.1 via 14 Amino Acids in the Carboxy Terminus of KCa3.1

Srivastava, Shekhar, Choudhury, Papiya, Li, Zhai, Liu, GongXin, Nadkarni, Vivek, Ko, Kyung, ...

KCa3.1 is an intermediate conductance Ca2+-activated K+ channel that is expressed predominantly in hematopoietic cells, smooth muscle cells, and epithelia where it functions to regulate membrane...

Phosphatidylinositol-3 Phosphatase Myotubularin-Related Protein 6 Negatively Regulates CD4 T Cells†

Srivastava, Shekhar, Ko, Kyung, Choudhury, Papiya, Li, Zhai, Johnson, Amanda K., Nadkarni, Vivek, ...

Intracellular Ca2+ levels rapidly rise following cross-linking of the T-cell receptor (TCR) and function as a critical intracellular second messenger in T-cell activation. It has been relatively...

A role for frequenin, a Ca2+-binding protein, as a regulator of Kv4 K+-currents

Nakamura, Tomoe Y., Pountney, David J., Ozaita, Ander, Nandi, Sumon, Ueda, Stefanie, Rudy, Bernardo, ...

Frequenin, a Ca2+-binding protein, has previously been implicated in the regulation of neurotransmission, possibly by affecting ion channel function. Here, we provide direct evidence that frequenin...

The Phosphatidylinositol 3-Phosphate Phosphatase Myotubularin- Related Protein 6 (MTMR6) Is a Negative Regulator of the Ca2+-Activated K+ Channel KCa3.1

Srivastava, Shekhar, Li, Zhai, Lin, Lin, Liu, GongXin, Ko, Kyung, Coetzee, William A., ...

Myotubularins (MTMs) belong to a large subfamily of phosphatases that dephosphorylate the 3′ position of phosphatidylinositol 3-phosphate [PI(3)P] and PI(3,5)P2. MTM1 is mutated in X-linked...

Phosphatidylinositol 3-Phosphate Indirectly Activates KCa3.1 via 14 Amino Acids in the Carboxy Terminus of KCa3.1

Srivastava, Shekhar, Choudhury, Papiya, Li, Zhai, Liu, GongXin, Nadkarni, Vivek, Ko, Kyung, ...

KCa3.1 is an intermediate conductance Ca2+-activated K+ channel that is expressed predominantly in hematopoietic cells, smooth muscle cells, and epithelia where it functions to regulate membrane...

Phosphatidylinositol-3 Phosphatase Myotubularin-Related Protein 6 Negatively Regulates CD4 T Cells†

Srivastava, Shekhar, Ko, Kyung, Choudhury, Papiya, Li, Zhai, Johnson, Amanda K., Nadkarni, Vivek, ...

Intracellular Ca2+ levels rapidly rise following cross-linking of the T-cell receptor (TCR) and function as a critical intracellular second messenger in T-cell activation. It has been relatively...

cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic β cells and rat INS-1 cells

Kang, Guoxin, Chepurny, Oleg G, Malester, Brian, Rindler, Michael J, Rehmann, Holger, Bos, Johannes L, ...

The Epac family of cAMP-regulated guanine nucleotide exchange factors (cAMPGEFs, also known as Epac1 and Epac2) mediate stimulatory actions of the second messenger cAMP on insulin secretion from...

Decreased connexin43 expression in the mouse heart potentiates pacing-induced remodeling of repolarizing currents

Kontogeorgis, Andrianos, Li, Xiaodong, Kang, Eunice Y., Feig, Jonathan E., Ponzio, Marc, Kang, Guoxin, ...

Gap junction redistribution and reduced expression, a phenomenon termed gap junction remodeling (GJR), is often seen in diseased hearts and may predispose toward arrhythmias. We have recently shown...

Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic β-cells and rat INS-1 cells

Kang, Guoxin, Leech, Colin A, Chepurny, Oleg G, Coetzee, William A, Holz, George G

Protein kinase A (PKA)-independent actions of adenosine 3′,5′-cyclic monophosphate (cAMP) are mediated by Epac, a cAMP sensor expressed in pancreatic β-cells. Evidence that Epac might mediate...