William F. Dietrich

Publication List Details

Period

1984 - 2006

Number

23

Co-Authors

Flagellin-Deficient Legionella Mutants Evade Caspase-1- and Naip5-Mediated Macrophage Immunity (2006)

Tao Ren, Dario S. Zamboni, Craig R. Roy, William F. Dietrich, Russell E. Vance

Macrophages from C57BL/6J (B6) mice restrict growth of the intracellular bacterial pathogen Legionella pneumophila. Restriction of bacterial growth requires caspase-1 and the leucine-rich...

The host resistance locus sst1 controls innate immunity to Listeria monocytogenes infection in immunodeficient mice (2004)

Boyartchuk, Victor, Rojas, Mauricio, Yan, Bo-Shiun, Jobe, Ousman, Hurt, Nicholas, Dorfman, David M., ...

Epidemiological, clinical, and experimental approaches have convincingly demonstrated that host resistance to infection with intracellular pathogens is significantly influenced by genetic...

Effects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas

Fazeli, Amin, Steen, Robert G., Dickinson, Stephanie L., Bautista, Dolores, Dietrich, William F., Bronson, Roderick T., ...

We have examined the effects of inactivation of the p53 tumor suppressor gene on the incidence of apoptotic cell death in two stages of the adenoma-to-carcinoma progression in the intestine: in early...

Genetic control of resistance to experimental infection with virulent Mycobacterium tuberculosis

Kramnik, Igor, Dietrich, William F., Demant, Peter, Bloom, Barry R.

Over 2 billion people are estimated to be infected with virulent Mycobacterium tuberculosis, yet fewer than 10% progress to clinical tuberculosis within their lifetime. Twin studies and variations in...

A natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunity

Shaw, Michael H., Boyartchuk, Victor, Wong, Sandy, Karaghiosoff, Marina, Ragimbeau, Josiane, Pellegrini, Sandra, ...

The B10.Q/J strain of mice was serendipitously discovered to be highly susceptible to infection by the intracellular protozoan parasite, Toxoplasma gondii but markedly resistant to induction of...

High-resolution Genetic and Physical Map of the Lgn1 Interval in C57BL/6J Implicates Naip2 or Naip5 in Legionella pneumophila Pathogenesis

Growney, Joseph D., Dietrich, William F.

Prior genetic and physical mapping has shown that the Naip gene cluster on mouse chromosome 13D1-D3 contains a gene, Lgn1, that is responsible for determining the permissivity of ex vivo macrophages...

Genomic Sequence Analysis of the Mouse Naip Gene Array

Endrizzi, Matthew G., Hadinoto, Vey, Growney, Joseph D., Miller, Webb, Dietrich, William F.

A mouse locus called Lgn1 determines differences in macrophage permissiveness for the intracellular replication of Legionella pneumophila. The only regional candidate genes for this phenotype...

Flagellin-Deficient Legionella Mutants Evade Caspase-1- and Naip5-Mediated Macrophage Immunity

Ren, Tao, Zamboni, Dario S, Roy, Craig R, Dietrich, William F, Vance, Russell E

Macrophages from C57BL/6J (B6) mice restrict growth of the intracellular bacterial pathogen Legionella pneumophila. Restriction of bacterial growth requires caspase-1 and the leucine-rich...

Spt3 plays opposite roles in filamentous growth in Saccharomyces cerevisiae and Candida albicans and is required for C. albicans virulence.

Laprade, Lisa, Boyartchuk, Victor L, Dietrich, William F, Winston, Fred

Spt3 of Saccharomyces cerevisiae is required for the normal transcription of many genes in vivo. Past studies have shown that Spt3 is required for both mating and sporulation, two events that...

Effects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas

Fazeli, Amin, Steen, Robert G., Dickinson, Stephanie L., Bautista, Dolores, Dietrich, William F., Bronson, Roderick T., ...

We have examined the effects of inactivation of the p53 tumor suppressor gene on the incidence of apoptotic cell death in two stages of the adenoma-to-carcinoma progression in the intestine: in early...

Genetic control of resistance to experimental infection with virulent Mycobacterium tuberculosis

Kramnik, Igor, Dietrich, William F., Demant, Peter, Bloom, Barry R.

Over 2 billion people are estimated to be infected with virulent Mycobacterium tuberculosis, yet fewer than 10% progress to clinical tuberculosis within their lifetime. Twin studies and variations in...

A natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunity

Shaw, Michael H., Boyartchuk, Victor, Wong, Sandy, Karaghiosoff, Marina, Ragimbeau, Josiane, Pellegrini, Sandra, ...

The B10.Q/J strain of mice was serendipitously discovered to be highly susceptible to infection by the intracellular protozoan parasite, Toxoplasma gondii but markedly resistant to induction of...

High-resolution Genetic and Physical Map of the Lgn1 Interval in C57BL/6J Implicates Naip2 or Naip5 in Legionella pneumophila Pathogenesis

Growney, Joseph D., Dietrich, William F.

Prior genetic and physical mapping has shown that the Naip gene cluster on mouse chromosome 13D1-D3 contains a gene, Lgn1, that is responsible for determining the permissivity of ex vivo macrophages...

Genomic Sequence Analysis of the Mouse Naip Gene Array

Endrizzi, Matthew G., Hadinoto, Vey, Growney, Joseph D., Miller, Webb, Dietrich, William F.

A mouse locus called Lgn1 determines differences in macrophage permissiveness for the intracellular replication of Legionella pneumophila. The only regional candidate genes for this phenotype...

Flagellin-Deficient Legionella Mutants Evade Caspase-1- and Naip5-Mediated Macrophage Immunity

Ren, Tao, Zamboni, Dario S, Roy, Craig R, Dietrich, William F, Vance, Russell E

Macrophages from C57BL/6J (B6) mice restrict growth of the intracellular bacterial pathogen Legionella pneumophila. Restriction of bacterial growth requires caspase-1 and the leucine-rich...

Spt3 plays opposite roles in filamentous growth in Saccharomyces cerevisiae and Candida albicans and is required for C. albicans virulence.

Laprade, Lisa, Boyartchuk, Victor L, Dietrich, William F, Winston, Fred

Spt3 of Saccharomyces cerevisiae is required for the normal transcription of many genes in vivo. Past studies have shown that Spt3 is required for both mating and sporulation, two events that...

The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice

Bernstein-Hanley, Isaac, Coers, Jörn, Balsara, Zarine R., Taylor, Gregory A., Starnbach, Michael N., Dietrich, William F.

Infections caused by the bacteria Chlamydia trachomatis contribute to diverse pathologies in a variety of human populations. We previously used a systemic model of C. trachomatis infection in mice to...

Legionella pneumophila Is Internalized by a Macropinocytotic Uptake Pathway Controlled by the Dot/Icm System and the Mouse Lgn1 Locus✪

Watarai, Masahisa, Derre, Isabelle, Kirby, James, Growney, Joseph D., Dietrich, William F., Isberg, Ralph R.

The products of the Legionella pneumophila dot/icm genes enable the bacterium to replicate within a macrophage vacuole. This study demonstrates that the Dot/Icm machinery promotes macropinocytotic...