Somers, Emily C., Marder, Wendy, Christman, Gregory M., Ognenovski, Vladimir, McCune, William Joseph
Objective Cyclophosphamide (CYC) therapy for systemic lupus erythematosus (SLE), a disease predominantly affecting women of childbearing age, causes an unacceptably high incidence of irreversible...
Sundgren, P.C., Pang, Y., Attwood, J.T., Jennings, J. E., Nan, B., Gebarski, Stephen S., ...
MRI and 2D-CSI spectroscopy were performed in eight patients with systemic lupus erythematosus who presented with acute onset of neuropsychiatric lupus (NP-SLE), and in seven normal controls to...
Degos' disease mimicking vasculitis (2004)
Kocheril, Sosa V., Blaivas, Mila, Appleton, Brent E., McCune, William Joseph, Ike, Robert W.
No abstract.
Deng, Chun, Kaplan, Mariana J., Yang, Jun, Ray, Donna, Zhang, Zhiyong, McCune, William Joseph, ...
Objective Previous studies have shown that inhibiting T cell DNA methylation causes a lupus-like disease by modifying gene expression. T cells from patients with lupus exhibit diminished levels of...
Crofford, Leslie J., Oates, James C., McCune, William Joseph, Gupta, Samardeep, Kaplan, Mariana J., Catella-Lawson, Francesca, ...
Specific inhibitors of cyclooxygenase 2 (COX-2) have been approved for the treatment of osteoarthritis and rheumatoid arthritis. Unlike nonsteroidal anti-inflammatory drugs, specific COX-2 inhibitors...
Cytogenetic abnormalities and therapy-related myelodysplastic syndromes in rheumatic disease (1998)
McCarthy, Conor J., Sheldon, Susan, Ross, Charles W., McCune, William Joseph
Objective To describe the myelodysplastic syndromes (MDS) and cytogenetic abnormalities that occur in patients who have been treated with alkylating drugs for their rheumatic disease. Methods...
Atrioventricular conduction in children of women with systemic lupus erythematosus (1993)
Goble, Monica Martin, McCune, William Joseph, Ellsworth, Janet, Sullivan, Donita B., Stern, Aaron M.
The neonatal lupus syndrome consists of transient cutaneous lupus lesions or permanent congenital complete heart block (or hepatic fibrosis), or both, in infants born to mothers with systemic lupus...
Defective CD2 pathway T cell activation in systemic lupus erythematosus (1991)
Fox, David A., Millard, Jo Ann, Treisman, Jonathan, Zeldes, Wendy, Bergman, Alice, Depper, Joel, ...
CD2 (T11; sheep erythrocyte receptor) is the surface component of an alternative, antigen-independent pathway of human T cell activation. The response to certain anti-CD2 antibodies is relatively...
Transient Lambert-Eaton myasthenic syndrome associated with systemic lupus erythematosus (1989)
Bromberg, Mark B., Albers, James W., McCune, William Joseph
We present a patient who developed the Lambert–Eaton myasthenic syndrome (LEMS) in association with systemic lupus erythematosus (SLE). Severe proximal weakness with electrodiagnostic evidence of...
McCune, William Joseph, Macguire, Anne, Aisen, Alex M., Gebarski, Stephen S.
Cranial magnetic resonance imaging in 28 systemic lupus erythematosus patients who had experienced 30 acute neuropsychiatric events showed focal brain lesions in 16 of 30 events (53%) and low brain...
MRI in osteoarthritis of the hip: Gradations of severity (1988)
Li, King C., Higgs, Jay, Aisen, Alex M., Buckwalter, Kenneth A., Martel, William, McCune, William Joseph
In a prospective study, 10 patients with well-documented osteoarthritis (O.A.) of the hips were imaged using spinecho pulse sequences (TR = 0.5 to 1.5 s and TE = 28 to 60 ms). After analyzing the...