Asih, Puji BS, Rogers, William O, Susanti, Agustina I, Rahmat, Agus, Rozi, Ismail E, Kusumaningtyas, Mariska A, ...
Abstract Background Drug resistant malaria poses an increasing public health problem in Indonesia, especially eastern Indonesia, where malaria is highly endemic. Widespread chloroquine (CQ)...
Rogers, William O, Sem, Rithy, Tero, Thong, Chim, Pheaktra, Lim, Pharath, Muth, Sinuon, ...
Abstract Background Resistance to anti-malarial drugs hampers control efforts and increases the risk of morbidity and mortality from malaria. The efficacy of standard therapies for uncomplicated...
Seasonal prevalence of malaria in West Sumba district, Indonesia (2009)
Syafruddin, Din, Asih, Puji, Dewi, Rita M, Coutrier, Farah, ...
Abstract Background Accurate information about the burden of malaria infection at the district or provincial level is required both to plan and assess local malaria control efforts. Although many...
Fry, Andrew E., Ghansa, Anita, Small, Kerrin S., Palma, Alejandro, Auburn, Sarah, Diakite, Mahamadou, ...
The prevalence of CD36 deficiency in East Asian and African populations suggests that the causal variants are under selection by severe malaria. Previous analysis of data from the International...
Sedegah, Martha, Rogers, William O., Belmonte, Arnel, Belmonte, Maria, Banania, Glenna, Patterson, Noelle, ...
We evaluated the capacity of the cationic lipid based formulation, Vaxfectin™, to enhance the immunogenicity and protective efficacy of DNA-based vaccine regimens in the Plasmodium yoelii murine...
Chappel, Jonathan A, Rogers, William O, Hoffman, Stephen L, Kang, Angray S
Abstract Background The circumsporozoite surface protein is the primary target of human antibodies against Plasmodium falciparum sporozoites, these antibodies are predominantly directed to the major...
Sedegah, Martha, Brice, Gary T., Rogers, William O., Doolan, Denise L., Charoenvit, Yupin, Jones, Trevor R., ...
The persistence of immunity to malaria induced in mice by a heterologous DNA priming and poxvirus boosting regimen was characterized. Mice were immunized by priming with DNA vaccine plasmids encoding...
Rogers, William O., Rogers, Miriam D., Hedstrom, Richard C., Hoffman, Stephen L.
Sporozoite surface protein 2 (SSP2) is a 140-kDa, protective sporozoite surface protein from Plasmodium yoelii distinct from the circumsporozoite protein (CSP). A genomic clone containing the SSP2...
Chappel, Jonathan A., Rogers, William O., Hoffman, Stephen L., Kang, Angray S.
The circumsporozoite surface protein is the primary target of human antibodies against Plasmodium falciparum sporozoites, these antibodies are predominantly directed to the major repetitive epitope...
Rogers, William O., Hoffman, Stephen L.
This invention relates to recombinant strains of Leishmania which express foreign proteins, useful for vaccination against infectious diseases. More particularly, this invention relates to strains of...
Immunogenicity and Protective Efficacy of a Plasmodium yoelii Hsp60 DNA Vaccine in BALB/c Mice
Sanchez, Gloria I., Sedegah, Martha, Rogers, William O., Jones, Trevor R., Sacci, John, Witney, Adam, ...
The gene encoding the 60-kDa heat shock protein of Plasmodium yoelii (PyHsp60) was cloned into the VR1012 and VR1020 mammalian expression vectors. Groups of 10 BALB/c mice were immunized...
Rogers, William O., Baird, J. Kevin, Kumar, Anita, Tine, John A., Weiss, Walter, Aguiar, João C., ...
A nonhuman primate model for malaria vaccine development allowing reliable, stringent sporozoite challenge and evaluation of both cellular and antibody responses is needed. We therefore constructed a...
Narum, David L., Kumar, Sanjai, Rogers, William O., Fuhrmann, Steven R., Liang, Hong, Oakley, Miranda, ...
In contrast to conventional vaccines, DNA and other subunit vaccines exclusively utilize host cell molecules for transcription and translation of proteins. The adenine plus thymine content of...
Sedegah, Martha, Brice, Gary T., Rogers, William O., Doolan, Denise L., Charoenvit, Yupin, Jones, Trevor R., ...
The persistence of immunity to malaria induced in mice by a heterologous DNA priming and poxvirus boosting regimen was characterized. Mice were immunized by priming with DNA vaccine plasmids encoding...
Rogers, William O., Weiss, Walter R., Kumar, Anita, Aguiar, João C., Tine, John A., Gwadz, Robert, ...
We tested a cytokine-enhanced, multiantigen, DNA priming and poxvirus boosting vaccine regimen for prevention of malaria in the Plasmodium knowlesi-rhesus macaque model system. Animals were primed...
Immunogenicity and Protective Efficacy of a Plasmodium yoelii Hsp60 DNA Vaccine in BALB/c Mice
Sanchez, Gloria I., Sedegah, Martha, Rogers, William O., Jones, Trevor R., Sacci, John, Witney, Adam, ...
The gene encoding the 60-kDa heat shock protein of Plasmodium yoelii (PyHsp60) was cloned into the VR1012 and VR1020 mammalian expression vectors. Groups of 10 BALB/c mice were immunized...
Rogers, William O., Baird, J. Kevin, Kumar, Anita, Tine, John A., Weiss, Walter, Aguiar, João C., ...
A nonhuman primate model for malaria vaccine development allowing reliable, stringent sporozoite challenge and evaluation of both cellular and antibody responses is needed. We therefore constructed a...
Narum, David L., Kumar, Sanjai, Rogers, William O., Fuhrmann, Steven R., Liang, Hong, Oakley, Miranda, ...
In contrast to conventional vaccines, DNA and other subunit vaccines exclusively utilize host cell molecules for transcription and translation of proteins. The adenine plus thymine content of...
Sedegah, Martha, Brice, Gary T., Rogers, William O., Doolan, Denise L., Charoenvit, Yupin, Jones, Trevor R., ...
The persistence of immunity to malaria induced in mice by a heterologous DNA priming and poxvirus boosting regimen was characterized. Mice were immunized by priming with DNA vaccine plasmids encoding...
Rogers, William O., Weiss, Walter R., Kumar, Anita, Aguiar, João C., Tine, John A., Gwadz, Robert, ...
We tested a cytokine-enhanced, multiantigen, DNA priming and poxvirus boosting vaccine regimen for prevention of malaria in the Plasmodium knowlesi-rhesus macaque model system. Animals were primed...
Seasonal prevalence of malaria in West Sumba district, Indonesia
Syafruddin, Din, Asih, Puji, Dewi, Rita M, Coutrier, Farah, ...
Fry, Andrew E., Ghansa, Anita, Small, Kerrin S., Palma, Alejandro, Auburn, Sarah, Diakite, Mahamadou, ...
The prevalence of CD36 deficiency in East Asian and African populations suggests that the causal variants are under selection by severe malaria. Previous analysis of data from the International...