William Schleif

Design of immunogens that present the crown of the HIV-1 V3 loop in a conformation competent to generate 447-52D-like antibodies (2006)

Chakraborty, Kausik, Durani, Venuka, Roshan Miranda, Edward, Citron, Michael, Liang, Xiaoping, Schleif, William, ...

gp120 is a subunit of the envelope glycoprotein of HIV-1. The third variable loop region of gp120 (V3 loop) contains multiple immunodominant epitopes and is also functionally important for deciding...

Design of immunogens that present the crown of the HIV-1 V3 loop in a conformation competent to generate 447-52D-like antibodies (2006)

Chakraborty, Kausik, Durani, Venuka, Roshan Miranda, Edward, Citron, Michael, Liang, Xiaoping, Schleif, William, ...

gp120 is a subunit of the envelope glycoprotein of HIV-1. The third variable loop region of gp120 (V3 loop) contains multiple immunodominant epitopes and is also functionally important for deciding...

Characterization of gp120 and its Single-Chain Derivatives, $gp120-CD4_D_1_2$ and gp120-M9: Implications for Targeting the $CD4_i$ Epitope in Human Immunodeficiency Virus Vaccine Design (2005)

Varadarajan, Raghavan, Sharma, Deepak, Chakraborty, Kausik, Patel, Mayuri, Citron, Michael, Sinha, Prem, ...

Single-chain derivatives of JRFL gp120 linked to the first two domains of human CD4 $(gp120-CD4_D_1_2)$ or to the CD4 miniprotein analog CD4M9 (gp120-M9), have been constructed. Biacore studies...

Characterization of gp120 and its Single-Chain Derivatives, $gp120-CD4_D_1_2$ and gp120-M9: Implications for Targeting the $CD4_i$ Epitope in Human Immunodeficiency Virus Vaccine Design (2005)

Varadarajan, Raghavan, Sharma, Deepak, Chakraborty, Kausik, Patel, Mayuri, Citron, Michael, Sinha, Prem, ...

Single-chain derivatives of JRFL gp120 linked to the first two domains of human CD4 $(gp120-CD4_D_1_2)$ or to the CD4 miniprotein analog CD4M9 (gp120-M9), have been constructed. Biacore studies...

Characterization of gp120 and Its Single-Chain Derivatives, gp120-CD4D12 and gp120-M9: Implications for Targeting the CD4i Epitope in Human Immunodeficiency Virus Vaccine Design

Varadarajan, Raghavan, Sharma, Deepak, Chakraborty, Kausik, Patel, Mayuri, Citron, Michael, Sinha, Prem, ...

Single-chain derivatives of JRFL gp120 linked to the first two domains of human CD4 (gp120-CD4D12) or to the CD4 miniprotein analog CD4M9 (gp120-M9), have been constructed. Biacore studies revealed...

High-Potency Human Immunodeficiency Virus Vaccination Leads to Delayed and Reduced CD8+ T-Cell Expansion but Improved Virus Control

Davenport, Miles P., Zhang, Lei, Bagchi, Ansuman, Fridman, Arthur, Fu, Tong-Ming, Schleif, William, ...

CD8+ T lymphocytes are thought to play an important role in the control of acute and chronic human immunodeficiency virus infections. However, there is a significant delay between infection and the...

A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope

Miller, Michael D., Geleziunas, Romas, Bianchi, Elisabetta, Lennard, Simon, Hrin, Renee, Zhang, Hangchun, ...

HIV-1 entry into cells is mediated by the envelope glycoprotein receptor-binding (gp120) and membrane fusion-promoting (gp41) subunits. The gp41 heptad repeat 1 (HR1) domain is the molecular target...

Characterization of gp120 and Its Single-Chain Derivatives, gp120-CD4D12 and gp120-M9: Implications for Targeting the CD4i Epitope in Human Immunodeficiency Virus Vaccine Design

Varadarajan, Raghavan, Sharma, Deepak, Chakraborty, Kausik, Patel, Mayuri, Citron, Michael, Sinha, Prem, ...

Single-chain derivatives of JRFL gp120 linked to the first two domains of human CD4 (gp120-CD4D12) or to the CD4 miniprotein analog CD4M9 (gp120-M9), have been constructed. Biacore studies revealed...

High-Potency Human Immunodeficiency Virus Vaccination Leads to Delayed and Reduced CD8+ T-Cell Expansion but Improved Virus Control

Davenport, Miles P., Zhang, Lei, Bagchi, Ansuman, Fridman, Arthur, Fu, Tong-Ming, Schleif, William, ...

CD8+ T lymphocytes are thought to play an important role in the control of acute and chronic human immunodeficiency virus infections. However, there is a significant delay between infection and the...

A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope

Miller, Michael D., Geleziunas, Romas, Bianchi, Elisabetta, Lennard, Simon, Hrin, Renee, Zhang, Hangchun, ...

HIV-1 entry into cells is mediated by the envelope glycoprotein receptor-binding (gp120) and membrane fusion-promoting (gp41) subunits. The gp41 heptad repeat 1 (HR1) domain is the molecular target...

Design of immunogens that present the crown of the HIV-1 V3 loop in a conformation competent to generate 447-52D-like antibodies

Chakraborty, Kausik, Durani, Venuka, Miranda, Edward Roshan, Citron, Michael, Liang, Xiaoping, Schleif, William, ...

gp120 is a subunit of the envelope glycoprotein of HIV-1. The third variable loop region of gp120 (V3 loop) contains multiple immunodominant epitopes and is also functionally important for deciding...