Wilson J. Ribot

Activity of the Bacillus anthracis20 kDa protective antigen component (2008)

Hammamieh, Rasha, Ribot, Wilson J, Abshire, Terry G, Jett, Marti, Ezzell, John

Abstract Background Anthrax is caused by Bacillus anthracis that produce two exotoxins, lethal toxin and edema toxin. The lethal toxin is composed of the lethal factor (LF) complexed with the cell...

Anthrax Lethal Toxin Impairs Innate Immune Functions of Alveolar Macrophages and Facilitates Bacillus anthracis Survival (2006)

Ribot, Wilson J., Panchal, Rekha G., Brittingham, Katherine C., Ruthel, Gordon, Kenny, Tara A., Lane, Douglas, ...

Alveolar macrophages (AM) are very important for pulmonary innate immune responses against invading inhaled pathogens because they directly kill the organisms and initiate a cascade of innate and...

Time-Lapse Confocal Imaging of Development of Bacillus anthracis in Macrophages (1998)

Ruthel, Gordon, Ribot, Wilson J., Bavari, Sina, Hoover, Timothy A.

Macrophages attempt to battle infection with Bacillus anthracis spores by phagocytosis of the spores. However, it is believed that B. anthracis spores may survive phagocytosis and may actually use...

Dendritic Cells Endocytose Bacillus Anthracis Spores: Implications for Anthrax Pathogenesis (1998)

Brittingham, Katherine C., Ruthel, Gordon, Panchal, Rekha G., Fuller, Claudette L., Ribot, Wilson J.

Phagocytosis of inhaled Bacillus anthracis spores and subsequent trafficking to lymph nodes are decisive events in the progression of inhaled anthrax because they initiate germination and...

The Animal Pathogen-Like Type III Secretion System is Required for the Intracellular Survival of Burkholderia mallei within J774.2 Macrophages (1998)

Ribot, Wilson J., Ulrich, Ricky L.

Burkholderia mallei is a highly infectious gram-negative pathogen and is the causative agent of human and animal glanders. By generating polar mutations (disruption of bsaQ and bsaZ) in the B. mallei...

The Animal Pathogen-Like Type III Secretion System Is Required for the Intracellular Survival of Burkholderia mallei within J774.2 Macrophages

Ribot, Wilson J., Ulrich, Ricky L.

Burkholderia mallei is a highly infectious gram-negative pathogen and is the causative agent of human and animal glanders. By generating polar mutations (disruption of bsaQ and bsaZ) in the B. mallei...

The Animal Pathogen-Like Type III Secretion System Is Required for the Intracellular Survival of Burkholderia mallei within J774.2 Macrophages

Ribot, Wilson J., Ulrich, Ricky L.

Burkholderia mallei is a highly infectious gram-negative pathogen and is the causative agent of human and animal glanders. By generating polar mutations (disruption of bsaQ and bsaZ) in the B. mallei...

Anthrax Lethal Toxin Impairs Innate Immune Functions of Alveolar Macrophages and Facilitates Bacillus anthracis Survival

Ribot, Wilson J., Panchal, Rekha G., Brittingham, Katherine C., Ruthel, Gordon, Kenny, Tara A., Lane, Douglas, ...

Alveolar macrophages (AM) are very important for pulmonary innate immune responses against invading inhaled pathogens because they directly kill the organisms and initiate a cascade of innate and...

Treatment of Experimental Anthrax with Recombinant Capsule Depolymerase▿

Scorpio, Angelo, Tobery, Steven A., Ribot, Wilson J., Friedlander, Arthur M.

Bacillus anthracis produces an antiphagocytic gamma-linked poly-d-glutamic acid capsule that is required for virulence. Capsule depolymerase (CapD) is a membrane-associated poly-γ-glutamate-specific...

In Vitro Intracellular Trafficking of Virulence Antigen during Infection by Yersinia pestis

DiMezzo, Tracy L., Ruthel, Gordon, Brueggemann, Ernst E., Hines, Harry B., Ribot, Wilson J., Chapman, Carol E., ...

Yersinia pestis, the causative agent of plague, encodes several essential virulence factors on a 70 kb plasmid, including the Yersinia outer proteins (Yops) and a multifunctional virulence antigen...

Burkholderia mallei tssM Encodes a Putative Deubiquitinase That Is Secreted and Expressed inside Infected RAW 264.7 Murine Macrophages▿ †

Shanks, John, Burtnick, Mary N., Brett, Paul J., Waag, David M., Spurgers, Kevin B., Ribot, Wilson J., ...

Burkholderia mallei, a category B biothreat agent, is a facultative intracellular pathogen that causes the zoonotic disease glanders. The B. mallei VirAG two-component regulatory system activates the...