Factors affecting the clinical outcome after neural transplantation in Parkinson's disease (2005)
Piccini, Paola, Pavese, Nicola, Hagell, Peter, Reimer, Jan, Björklund, Anders, Oertel, Wolfgang H., ...
Intrastriatal grafts of embryonic mesencephalic tissue can survive in the brains of patients with Parkinson's disease, but the degree of symptomatic relief is highly variable and some cases develop...
Du, Yansheng, Wei, Xing, Dodel, Richard, Sommer, Norbert, Hampel, Harald, Gao, Feng, ...
The accumulation of β-amyloid (Aβ) in neuritic plaques is thought to be causative for the progression of Alzheimer's disease (AD). Recently, both active immunization and passive administration of...
Du, Yansheng, Wei, Xing, Dodel, Richard, Sommer, Norbert, Hampel, Harald, Gao, Feng, ...
The accumulation of β‐amyloid (Aβ) in neuritic plaques is thought to be causative for the progression of Alzheimer’s disease (AD). Recently, both active immunization and passive...
Du, Yansheng, Wei, Xing, Dodel, Richard, Sommer, Norbert, Hampel, Harald, Gao, Feng, ...
The accumulation of β-amyloid (Aβ) in neuritic plaques is thought to be causative for the progression of Alzheimer's disease (AD). Recently, both active immunization and passive administration of...
Dyskinesias following neural transplantation in Parkinson's disease. (2002)
Hagell, Peter, Piccini, Paola, Björklund, Anders, Brundin, Patrik, Rehncrona, Stig, Widner, Håkan, ...
Severe dyskinesias during the 'off' phases (periods of increased Parkinson's disease (PD) disability) have been observed following intrastriatal transplantation of human embryonic mesencephalic...
Jacobsen, Marc, Cepok, Sabine, Quak, Elfriede, Happel, Michael, Gaber, Rami, Ziegler, Andreas, ...
Multiple sclerosis is a chronic inflammatory demyelinating disease of the CNS. Although the aetiology of multiple sclerosis is still unknown, it is widely believed that T cells play a central role in...
Cepok, Sabine, Jacobsen, Marc, Schock, Sabine, Omer, Bilal, Jaekel, Steffi, Böddeker, Inke, ...
Multiple sclerosis is a chronic inflammatory and demyelinating disease of the CNS with, as yet, an unknown aetiology. Temporal profile, intensity and treatment responses are highly variable in...
Brundin, Patrik, Pogarell, Oliver, Hagell, Peter, Piccini, Paola, Widner, Håkan, Schrag, Anette, ...
Five parkinsonian patients were transplanted bilaterally into the putamen and caudate nucleus with human embryonic mesencephalic tissue from between seven and nine donors. To increase graft survival,...
München, Techn. Univ., Habil.-Schr., 1986.
The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease
Höglinger, Günter U., Breunig, Joshua J., Depboylu, Candan, Rouaux, Caroline, Michel, Patrick P., Alvarez-Fischer, Daniel, ...
The mechanisms leading to degeneration of dopaminergic neurons (DNs) in the substantia nigra of patients with Parkinson's disease (PD) are not completely understood. Here, we show, in the postmortem...
Cost of Illness and its Predictors for Parkinson's Disease in Germany
Annika E. Spottke, Martin Reuter, Olaf Machat, Bernhard Bornschein, Sonja Von Campenhausen, Karin Berger, ...
Objective: To prospectively evaluate the health economic burden of patients with Parkinson's disease (PD) in Germany over a 6-month observation period and to identify the predictors of these costs....
Richard C. Dodel, Karin Berger, Wolfgang H. Oertel
Idiopathic Parkinson's disease (PD) is a common chronic progressive neurodegenerative disorder associated with the progressive loss of dopaminergic neurons in the substantia nigra. The natural course...
The Economic Impact of Parkinson`s Disease: An Estimation Based on a 3-Month Prospective Analysis
Richard C. Dodel, Marikka Singer, Rudolf Kohne-Volland, Thomas Szucs, Bernard Rathay, Erich Scholz, ...
Objective: This study prospectively assesses the medical costs of Parkinson's disease (PD). Design: Over a period of 3 months (from July to September 1995), patients with PD documented all items of...
Costs of Illness in a Russian Cohort of Patients with Parkinson's Disease
Yaroslav Winter, Sonja Von Campenhausen, Georgy Popov, Jens P. Reese, Jens Klotsche, Kai Btzel, ...
Background: The economic burden associated with Parkinson's disease (PD) is increasing as the worldwide population ages. While cost-of-illness studies for PD from developed countries have recently...
Tackenberg, Björn, Jelčić, Ilijas, Baerenwaldt, Anne, Oertel, Wolfgang H., Sommer, Norbert, Nimmerjahn, Falk, ...
The inhibitory Fc-γ receptor FcγRIIB, expressed on myeloid and B cells, has a critical role in the balance of tolerance and autoimmunity, and is required for the antiinflammatory activity of...
Once-daily transdermal rivastigmine in the treatment of Alzheimer’s disease
Wentrup, Andreas, Oertel, Wolfgang H, Dodel, Richard
During the past decade, transdermal delivery systems (TDS) have become increasingly important for treating neurologic and psychiatric disorders. The rivastigmine patch was the first patch to be...