Umgelter, Andreas, Wagner, Katrin, Reindl, Wolfgang, Nurtsch, Nils, Huber, Wolfgang, Schmid, Roland M
Abstract Background Patients with advanced cirrhosis of the liver typically display circulatory disturbance. Haemodynamic management may be critical for avoiding and treating functional renal failure...
Umgelter, Andreas, Reindl, Wolfgang, Wagner, Katrin S, Franzen, Michael, Stock, Konrad, Schmid, Roland M, ...
Abstract Introduction Circulatory dysfunction in cirrhotic patients may cause a specific kind of functional renal failure termed hepato-renal syndrome (HRS). It contributes to the high incidence of...
Mayr, Juliane, Haselhorst, Thomas Erwin, Langereis, Martijn A., Dyason, Jeffrey Clifford, Huber, Wolfgang, Frey, Barbara, ...
Yes
Mayr, Juliane, Haselhorst, Thomas Erwin, Langereis, Martijn A., Dyason, Jeffrey Clifford, Huber, Wolfgang, Frey, Barbara, ...
Casneuf, Tineke, Van De Peer, Yves, Huber, Wolfgang
Abstract Background Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, correlated...
Ringo – an R/Bioconductor package for analyzing ChIP-chip readouts (2007)
Toedling, Joern, Skylar, Oleg, Krueger, Tammo, Fischer, Jenny J, Sperling, Silke, Huber, Wolfgang
No abstract available.
Making the most of high-throughput protein-interaction data (2007)
Gentleman, Robert, Huber, Wolfgang
Abstract We review the estimation of coverage and error rate in high-throughput protein-protein interaction datasets and argue that reports of the low quality of such data are to a substantial extent...
Graphs in molecular biology (2007)
Huber, Wolfgang, Carey, Vincent J, Long, Li, Falcon, Seth, Gentleman, Robert
Abstract Graph theoretical concepts are useful for the description and analysis of interactions and relationships in biological systems. We give a brief introduction into some of the concepts and...
Coverage and error models of protein-protein interaction data by directed graph analysis (2007)
Chiang, Tony, Scholtens, Denise, Sarkar, Deepayan, Gentleman, Robert, Huber, Wolfgang
Abstract Using a directed graph model for bait to prey systems and a multinomial error model, we assessed the error statistics in all published large-scale datasets for Saccharomyces cerevisiae and...
Ringo – an R/Bioconductor package for analyzing ChIP-chip readouts (2007)
Toedling, Joern, Sklyar, Oleg, Huber, Wolfgang
Abstract Background Chromatin immunoprecipitation combined with DNA microarrays ( ChIP-chip ) is a high-throughput assay for DNA-protein-binding or post-translational chromatin/histone modifications....
Steigele, Stephan, Huber, Wolfgang, Stocsits, Claudia, Stadler, Peter F, Nieselt, Kay
Abstract Background Non-coding RNAs (ncRNAs) are an emerging focus for both computational analysis and experimental research, resulting in a growing number of novel, non-protein coding transcripts...
Is supra-ventricular arrhythmia a reason for the bad performance of the FlowTrac device? (2007)
Umgelter, Andreas, Reindl, Wolfgang, Schmid, Roland M, Huber, Wolfgang
No abstract available.
Genomic organization of transcriptomes in mammals: coregulation and cofunctionality (2007)
Purmann, Antje, Toedling, Joern, Schueler, Markus, Carninci, Piero, Lehrach, Hans, Hayashizaki, Yoshihide, ...
In studies of their transcriptional activity, genomes have shown a high order of organization. We assessed the question of how genomically neighboring genes are transcriptionally coupled across...
Ringo – an R/Bioconductor package for analyzing ChIP-chip readouts (2007)
Toedling, Joern, Skylar, Oleg, Krueger, Tammo, Fischer, Jenny J., Sperling, Silke, Huber, Wolfgang
Hahne, Florian, Arlt, Dorit, Sauermann, Mamatha, Majety, Meher, Poustka, Annemarie, Wiemann, Stefan, ...
Abstract Highthroughput cell-based assays with flow cytometric readout provide a powerful technique for identifying components of biologic pathways and their interactors. Interpretation of these...
Analysis of cell-based RNAi screens (2006)
Boutros, Michael, Brás, Lígia P, Huber, Wolfgang
Abstract RNA interference (RNAi) screening is a powerful technology for functional characterization of biological pathways. Interpretation of RNAi screens requires computational and statistical...
Visualizing Genomic Data (2006)
Gentleman, Robert, Hahne, Florian, Huber, Wolfgang
The advent of experimental techniques capable of probing biomolecules and cells at high levels of resolution has led to a rapid change in the methods used for the analysis of experimental molecular...
Visualizing Genomic Data (2006)
Gentleman, Robert, Hahne, Florian, Huber, Wolfgang
The advent of experimental techniques capable of probing biomolecules and cells at high levels of resolution has led to a rapid change in the methods used for the analysis of experimental molecular...
Visualizing Genomic Data (2006)
Gentleman, Robert, Hahne, Florian, Huber, Wolfgang
The advent of experimental techniques capable of probing biomolecules and cells at high levels of resolution has led to a rapid change in the methods used for the analysis of experimental molecular...
Visualizing Genomic Data (2006)
Gentleman, Robert, Hahne, Florian, Huber, Wolfgang
The advent of experimental techniques capable of probing biomolecules and cells at high levels of resolution has led to a rapid change in the methods used for the analysis of experimental molecular...
An introduction to low-level analysis methods of DNA microarray data (2005)
Huber, Wolfgang, Von Heydebreck, Anja, Vingron, Martin
This article gives an overview over the methods used in the low--level analysis of gene expression data generated using DNA microarrays. This type of experiment allows to determine relative levels of...
An introduction to low-level analysis methods of DNA microarray data (2005)
Huber, Wolfgang, Von Heydebreck, Anja, Vingron, Martin
This article gives an overview over the methods used in the low--level analysis of gene expression data generated using DNA microarrays. This type of experiment allows to determine relative levels of...
An introduction to low-level analysis methods of DNA microarray data (2005)
Huber, Wolfgang, Von Heydebreck, Anja, Vingron, Martin
This article gives an overview over the methods used in the low--level analysis of gene expression data generated using DNA microarrays. This type of experiment allows to determine relative levels of...
An introduction to low-level analysis methods of DNA microarray data (2005)
Huber, Wolfgang, Von Heydebreck, Anja, Vingron, Martin
This article gives an overview over the methods used in the low--level analysis of gene expression data generated using DNA microarrays. This type of experiment allows to determine relative levels of...
On the Synthesis of Microarray Experiments (2005)
Gentleman, Robert, Ruschhaupt, Markus, Huber, Wolfgang
With many different investigators studying the same disease and with a strong commitment to publish supporting data in the scientific community, there are often many different datasets available for...
On the Synthesis of Microarray Experiments (2005)
Gentleman, Robert, Ruschhaupt, Markus, Huber, Wolfgang
With many different investigators studying the same disease and with a strong commitment to publish supporting data in the scientific community, there are often many different datasets available for...
On the Synthesis of Microarray Experiments (2005)
Gentleman, Robert, Ruschhaupt, Markus, Huber, Wolfgang
With many different investigators studying the same disease and with a strong commitment to publish supporting data in the scientific community, there are often many different datasets available for...
Sueltmann, Holger, Von Heydebreck, Anja, Huber, Wolfgang, Kuner, Ruprecht, Buness, Andreas, Vogt, Markus, ...
Current diagnosis of renal cancer consists of histopathologic examination of tissue sections and classification into tumor stages and grades of malignancy. Until recently, molecular differences...
A Compendium to Ensure Computational Reproducibility in High-Dimensional Classification Tasks (2004)
Ruschhaupt, Markus, Huber, Wolfgang, Poustka, Annemarie, Mansmann, Ulrich
We demonstrate a concept and implementation of a compendium for the classification of high-dimensional data from microarray gene expression profiles. A compendium is an interactive document that...
A Compendium to Ensure Computational Reproducibility in High-Dimensional Classification Tasks (2004)
Ruschhaupt, Markus, Huber, Wolfgang, Poustka, Annemarie, Mansmann, Ulrich
We demonstrate a concept and implementation of a compendium for the classification of high-dimensional data from microarray gene expression profiles. A compendium is an interactive document that...
A Compendium to Ensure Computational Reproducibility in High-Dimensional Classification Tasks (2004)
Ruschhaupt, Markus, Huber, Wolfgang, Poustka, Annemarie, Mansmann, Ulrich
We demonstrate a concept and implementation of a compendium for the classification of high-dimensional data from microarray gene expression profiles. A compendium is an interactive document that...
A Compendium to Ensure Computational Reproducibility in High-Dimensional Classification Tasks (2004)
Ruschhaupt, Markus, Huber, Wolfgang, Poustka, Annemarie, Mansmann, Ulrich
We demonstrate a concept and implementation of a compendium for the classification of high-dimensional data from microarray gene expression profiles. A compendium is an interactive document that...
Bioconductor: open software development for computational biology and bioinformatics (2004)
Gentleman, Robert C, Carey, Vincent J, Bates, Douglas M, Bolstad, Ben, Dettling, Marcel, Dudoit, Sandrine, ...
Abstract The Bioconductor project is an initiative for the collaborative creation of extensible software for computational biology and bioinformatics. The goals of the project include: fostering...
Differential Expression with the Bioconductor Project (2004)
Von Heydebreck,Anja, Huber,Wolfgang, Gentleman,Robert
A basic, yet challenging task in the analysis of microarray gene expression data is the identification of changes in gene expression that are associated with particular biological conditions. We...
Differential Expression with the Bioconductor Project (2004)
Von Heydebreck, Anja, Huber, Wolfgang, Gentleman, Robert
A basic, yet challenging task in the analysis of microarray gene expression data is the identification of changes in gene expression that are associated with particular biological conditions. We...
Differential Expression with the Bioconductor Project (2004)
Von Heydebreck, Anja, Huber, Wolfgang, Gentleman, Robert
A basic, yet challenging task in the analysis of microarray gene expression data is the identification of changes in gene expression that are associated with particular biological conditions. We...
Differential Expression with the Bioconductor Project (2004)
Von Heydebreck, Anja, Huber, Wolfgang, Gentleman, Robert
A basic, yet challenging task in the analysis of microarray gene expression data is the identification of changes in gene expression that are associated with particular biological conditions. We...
Differential Expression with the Bioconductor Project (2004)
Von Heydebreck, Anja, Huber, Wolfgang, Gentleman, Robert
A basic, yet challenging task in the analysis of microarray gene expression data is the identification of changes in gene expression that are associated with particular biological conditions. We...
Schneider, Jörg, Buneß, Andreas, Huber, Wolfgang, Volz, Joachim, Kioschis, Petra, Hafner, Mathias, ...
Abstract Background The requirement of a large amount of high-quality RNA is a major limiting factor for microarray experiments using biopsies. An average microarray experiment requires 10–100 μg...
Error models for microarray intensities (2004)
Huber,Wolfgang, Von Heydebreck,Anja, Vingron,Martin
We derive the additive-multiplicative error model for microarray intensities, and describe two applications. For the detection of differentially expressed genes, we obtain a statistic whose variance...
Error models for microarray intensities (2004)
Huber, Wolfgang, Von Heydebreck, Anja, Vingron, Martin
We derive the additive-multiplicative error model for microarray intensities, and describe two applications. For the detection of differentially expressed genes, we obtain a statistic whose variance...
Error models for microarray intensities (2004)
Huber, Wolfgang, Von Heydebreck, Anja, Vingron, Martin
We derive the additive-multiplicative error model for microarray intensities, and describe two applications. For the detection of differentially expressed genes, we obtain a statistic whose variance...
Error models for microarray intensities (2004)
Huber, Wolfgang, Von Heydebreck, Anja, Vingron, Martin
We derive the additive-multiplicative error model for microarray intensities, and describe two applications. For the detection of differentially expressed genes, we obtain a statistic whose variance...
Error models for microarray intensities (2004)
Huber, Wolfgang, Von Heydebreck, Anja, Vingron, Martin
We derive the additive-multiplicative error model for microarray intensities, and describe two applications. For the detection of differentially expressed genes, we obtain a statistic whose variance...
Bioconductor: Open software development for computational biology and bioinformatics (2004)
Gentleman, Robert C., Carey, Vincent J., Bates, Douglas J., Bolstad, Benjamin M., Dettling, Marcel, Dudoit, Sandrine, ...
The Bioconductor project is an initiative for the collaborative creation of extensible software for computational biology and bioinformatics. We detail some of the design decisions, software...
Bioconductor: Open software development for computational biology and bioinformatics (2004)
Gentleman, Robert C., Carey, Vincent J., Bates, Douglas J., Bolstad, Benjamin M., Dettling, Marcel, Dudoit, Sandrine, ...
The Bioconductor project is an initiative for the collaborative creation of extensible software for computational biology and bioinformatics. We detail some of the design decisions, software...
Bioconductor: Open software development for computational biology and bioinformatics (2004)
Gentleman, Robert C., Carey, Vincent J., Bates, Douglas J., Bolstad, Benjamin M., Dettling, Marcel, Dudoit, Sandrine, ...
The Bioconductor project is an initiative for the collaborative creation of extensible software for computational biology and bioinformatics. We detail some of the design decisions, software...
Bioconductor: Open software development for computational biology and bioinformatics (2004)
Gentleman, Robert C., Carey, Vincent J., Bates, Douglas J., Bolstad, Benjamin M., Dettling, Marcel, Dudoit, Sandrine, ...
The Bioconductor project is an initiative for the collaborative creation of extensible software for computational biology and bioinformatics. We detail some of the design decisions, software...
Differential Expression with the Bioconductor Project (2004)
Von Heydebreck, Anja, Huber, Wolfgang, Gentleman, Robert
A basic, yet challenging task in the analysis of microarray gene expression data is the identification of changes in gene expression that are associated with particular biological conditions. We...
Error models for microarray intensities (2004)
Huber, Wolfgang, Von Heydebreck, Anja, Vingron, Martin
We derive the additive-multiplicative error model for microarray intensities, and describe two applications. For the detection of differentially expressed genes, we obtain a statistic whose variance...
Gunawan,Bastian, Von Heydebreck,Anja, Fritsch,Thekla, Huber,Wolfgang, Ringert,Rolf-Hermann, Jakse,Gerhard, ...
We evaluated clinical characteristics, patient outcome (mean follow-up, 47 months), and cytogenetic abnormalities in the largest as yet reported cytogenetic series of 47 primary and 11 secondary...
Analysis of microarray gene expression data (2003)
Huber,Wolfgang, Heydebreck,Anja Von, Vingron,Martin
This article reviews the methods utilized in processing and analysis of gene expression data generated using DNA microarrays. This type of experiment allows to determine relative levels of mRNA...
Analysis of Microarray Gene Expression Data (2003)
Wolfgang Huber, Anja Von Heydebreck, Martin Vingron
This article reviews the methods utilized in processing and analysis of gene expression data generated using DNA microarrays. This type of experiment allows to determine relative levels of mRNA...
Parameter estimation for the calibration and variance stabilization of microarray data (2003)
Huber,Wolfgang, Von Heydebreck,Anja, Sültmann,Holger, Poustka,Annemarie, Vingron,Martin
We derive and validate an estimator for the parameters of a transformation for the joint calibration (normalization) and variance stabilization of microarray intensity data. With this, the variances...
Parameter estimation for the calibration and variance stabilization of microarray data (2003)
Huber, Wolfgang, Von Heydebreck, Anja, Sueltmann, Holger, Poustka, Annemarie, Vingron, Martin
We derive and validate an estimator for the parameters of a transformation for the joint calibration (normalization) and variance stabilization of microarray intensity data. With this, the variances...
Parameter estimation for the calibration and variance stabilization of microarray data (2003)
Huber, Wolfgang, Von Heydebreck, Anja, Sueltmann, Holger, Poustka, Annemarie, Vingron, Martin
We derive and validate an estimator for the parameters of a transformation for the joint calibration (normalization) and variance stabilization of microarray intensity data. With this, the variances...
Parameter estimation for the calibration and variance stabilization of microarray data (2003)
Huber, Wolfgang, Von Heydebreck, Anja, Sueltmann, Holger, Poustka, Annemarie, Vingron, Martin
We derive and validate an estimator for the parameters of a transformation for the joint calibration (normalization) and variance stabilization of microarray intensity data. With this, the variances...
Parameter estimation for the calibration and variance stabilization of microarray data (2003)
Huber, Wolfgang, Von Heydebreck, Anja, Sueltmann, Holger, Poustka, Annemarie, Vingron, Martin
We derive and validate an estimator for the parameters of a transformation for the joint calibration (normalization) and variance stabilization of microarray intensity data. With this, the variances...
Gunawan, Bastian, Von Heydebreck, Anja, Fritsch, Thekla, Huber, Wolfgang, Ringert, Rolf-Hermann, Jakse, Gerhard, ...
We evaluated clinical characteristics, patient outcome (mean follow-up, 47 months), and cytogenetic abnormalities in the largest as yet reported cytogenetic series of 47 primary and 11 secondary...
Parameter estimation for the calibration and variance stabilization of microarray data (2003)
Huber, Wolfgang, Von Heydebreck, Anja, Sültmann, Holger, Poustka, Annemarie, Vingron, Martin
We derive and validate an estimator for the parameters of a transformation for the joint calibration (normalization) and variance stabilization of microarray intensity data. With this, the variances...
Analysis of microarray gene expression data (2003)
Huber, Wolfgang, Heydebreck, Anja Von, Vingron, Martin
This article reviews the methods utilized in processing and analysis of gene expression data generated using DNA microarrays. This type of experiment allows to determine relative levels of mRNA...
Variance Sabilization and Robust Normalization for Microarray Gene Expression Data (2002)
Anja Von Heydebreck, Wolfgang Huber, Annemarie Poustka
We introduce a statistical model for microarray gene expression data that comprises data calibration, the quantification of differential gene expression, and the quantification of measurement error....
Huber,Wolfgang, Von Heydebreck,Anja, Sültmann,Holger, Poustka,Annemarie, Vingron,Martin
We introduce a statistical model for microarray gene expression data that comprises data calibration, the quantification of differential expression, and the quantification of measurement error. In...
Huber, Wolfgang, Von Heydebreck, Anja, Sültmann, Holger, Poustka, Annemarie, Vingron, Martin
We introduce a statistical model for microarray gene expression data that comprises data calibration, the quantification of differential expression, and the quantification of measurement error. In...
Anja Von Heydebreck, Wolfgang Huber, Annemarie Poustka
We present a new class discovery method for microarray gene expression data. Based on a collection of gene expression profiles from different tissue samples, the method searches for binary class...
Miscellaneous electricity use in U.S. homes (1999)
Sanchez, Marla C., Koomey, Jonathan G., Moezzi, Mithra M., Meier, Alan, Huber, Wolfgang
Historically, residential energy and carbon saving efforts have targeted conventional end uses such as water heating, lighting and refrigeration. The emergence of new household appliances has...
Reducing Leaking Electricity to 1 Watt (1998)
Meier, A.K., Huber, Wolfgang, Rosen, Karen
In this study we examine some specific opportunities to reduce standby losses in electronic appliances. A review of power consumption levels for the major components responsible for standby functions...
Dynamik stark getriebener offener Quantensysteme / (1998)
Freiburg (Breisgau), Universiẗat, Diss., 1998 (Nicht für den Austausch).
Results from the investigations on leaking electricity in the USA (1997)
Standby electricity use or leaking electricity is the energy consumed by appliances when they are switched off or not performing their principal function. The combination of field measurements and...
A Fast Monte Carlo Algorithm for Non-Equilibrium Systems (1996)
Wolfgang Huber, Francesco Petruccione
A fast method for the Monte Carlo solution of the balance equations which arise in non--equilibrium thermodynamics is suggested. It is applicable to chemical kinetics, reaction--diffusion processes,...