Wolfgang Reindl

Inhibition of Polo-like Kinase 1 by Small Molecules Targeting the Polo-Box Domain (2008)

Reindl, Wolfgang

The serine/threonine kinase Polo-like kinase 1 (Plk1) is a key regulator of multiple stages of mitosis. It is overexpressed in many types of human cancers and has been implicated as an adverse...

Haemodynamic effects of plasma-expansion with hyperoncotic albumin in cirrhotic patients with renal failure: a prospective interventional study (2008)

Umgelter, Andreas, Wagner, Katrin, Reindl, Wolfgang, Nurtsch, Nils, Huber, Wolfgang, Schmid, Roland M

Abstract Background Patients with advanced cirrhosis of the liver typically display circulatory disturbance. Haemodynamic management may be critical for avoiding and treating functional renal failure...

Effects of plasma expansion with albumin and paracentesis on haemodynamics and kidney function in critically ill cirrhotic patients with tense ascites and hepatorenal syndrome: a prospective uncontrolled trial (2008)

Umgelter, Andreas, Reindl, Wolfgang, Wagner, Katrin S, Franzen, Michael, Stock, Konrad, Schmid, Roland M, ...

Abstract Introduction Circulatory dysfunction in cirrhotic patients may cause a specific kind of functional renal failure termed hepato-renal syndrome (HRS). It contributes to the high incidence of...

EchoBASE: an integrated post-genomic database for Escherichia coli (2005)

Misra, Raju V., Horler, Richard S. P., Reindl, Wolfgang, Goryanin, Igor I., Thomas, Gavin H.

EchoBASE (http://www.ecoli-york.org) is a relational database designed to contain and manipulate information from post-genomic experiments using the model bacterium Escherichia coli K-12. Its aim is...

EchoBASE: an integrated post-genomic database for Escherichia coli

Misra, Raju V., Horler, Richard S. P., Reindl, Wolfgang, Goryanin, Igor I., Thomas, Gavin H.

EchoBASE (http://www.ecoli-york.org) is a relational database designed to contain and manipulate information from post-genomic experiments using the model bacterium Escherichia coli K-12. Its aim is...

EchoBASE: an integrated post-genomic database for Escherichia coli

Misra, Raju V., Horler, Richard S. P., Reindl, Wolfgang, Goryanin, Igor I., Thomas, Gavin H.

EchoBASE (http://www.ecoli-york.org) is a relational database designed to contain and manipulate information from post-genomic experiments using the model bacterium Escherichia coli K-12. Its aim is...

Essential crosstalk between myeloid and lymphoid cells for development of chronic colitis in myeloid-specific signal transducer and activator of transcription 3-deficient mice

Reindl, Wolfgang, Weiss, Susanne, Lehr, Hans-Anton, Förster, Irmgard

Dysregulated cytokine responsiveness by myeloid cells can be a trigger for the development of chronic inflammation as well as inflammatory bowel disease. Thus, mice with a myeloid-specific defect in...

Compartmentalized Production of CCL17 In Vivo: Strong Inducibility in Peripheral Dendritic Cells Contrasts Selective Absence from the Spleen

Alferink, Judith, Lieberam, Ivo, Reindl, Wolfgang, Behrens, Andrea, Weiß, Susanne, Hüser, Norbert, ...

Dendritic cells (DCs)* fulfill an important regulatory function at the interface of the innate and adaptive immune system. The thymus and activation-regulated chemokine (TARC/CCL17) is produced by...

Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF-κB and MAPK activation to selectively control cytokine production

Gross, Olaf, Grupp, Christina, Steinberg, Christian, Zimmermann, Stephanie, Strasser, Dominikus, Hannesschläger, Nicole, ...

Natural killer (NK) cells are innate immune cells that mediate resistance against viruses and tumors. They express multiple activating receptors that couple to immunoreceptor tyrosine-based...

Decreased Susceptibility of Mice to Infection with Listeria monocytogenes in the Absence of Interleukin-18▿

Lochner, Matthias, Kastenmüller, Kathrin, Neuenhahn, Michael, Weighardt, Heike, Busch, Dirk H., Reindl, Wolfgang, ...

The induction of proinflammatory cytokines such as gamma interferon (IFN-γ) and tumor necrosis factor alpha is crucial for the early control of bacterial infections. Since interleukin-18 (IL-18)...