Wolfgang Zimmermann

Species-specific evolution of immune receptor tyrosine based activation motif-containing CEACAM1-related immune receptors in the dog (2007)

Kammerer, Robert, Popp, Tanja, Härtle, Stefan, Singer, Bernhard B, Zimmermann, Wolfgang

Abstract Background Although the impact of pathogens on the evolution of the mammalian immune system is still under debate, proteins, which both regulate immune responses and serve as cellular...

Characterization of gastric adenocarcinoma cell lines established from CEA424/SV40 T antigen-transgenic mice with or without a human CEAtransgene (2006)

Nöckel, Jessica, Van Den Engel, Natasja K, Winter, Hauke, Hatz, Rudolf A, Zimmermann, Wolfgang, Kammerer, Robert

Abstract Background Gastric carcinoma is one of the most frequent cancers worldwide. Patients with gastric cancer at an advanced disease stage have a poor prognosis, due to the limited efficacy of...

Conservation of pregnancy-specific glycoprotein (PSG) N domains following independent expansions of the gene families in rodents and primates (2005)

McLellan, Andrew S, Zimmermann, Wolfgang, Moore, Tom

Abstract Background Rodent and primate pregnancy-specific glycoprotein ( PSG ) gene families have expanded independently from a common ancestor and are expressed virtually exclusively in placental...

Structure and evolution of the mouse pregnancy-specific glycoprotein (Psg) gene locus (2005)

McLellan, Andrew S, Fischer, Beate, Dveksler, Gabriela, Hori, Tomomi, Wynne, Freda, Ball, Melanie, ...

Abstract Background The pregnancy-specific glycoprotein ( Psg ) genes encode proteins of unknown function, and are members of the carcinoembryonic antigen ( Cea ) gene family, which is a member of...

Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast Candida glabrata (2003)

Wong, Simon, Fares, Mario A, Zimmermann, Wolfgang, Butler, Geraldine, Wolfe, Kenneth H

Abstract Background Candida glabrata is a pathogenic yeast of increasing medical concern. It has been regarded as asexual since it was first described in 1917, yet phylogenetic analyses have revealed...

Die industrielle Arbeitswelt der DDR unter dem Primat der sozialistischen Ideologie : exemplarisch untersucht am Schrifttum über Nacht- und Schichtarbeit (2000)

Zimmermann, Wolfgang

Gegenstand der vorliegenden Untersuchung ist die interdisziplinäre und systemübergreifende Analyse der Nacht- und Schichtarbeit. Der Verfasser diskutiert die Handhabung, Darstellung und Bewertung...

CGM2, a Member of the Carcinoembryonic Antigen Gene Family is Down- Regulated in Colorectal Carcinomas (1994)

Thompson, John A., Zimmermann, Wolfgang, Nollau, Peter, Neumaier, Michael, Weber-Arden, Julia, Schrewe, Heinrich, ...

We have determined the precise chromosomal location, the exon structure, and the expression pattern of CGM2, a member of the carcinoembryonic antigen (CEA) gene family. CGM2 cDNA was amplified by...

Mice Transgenic for the Human Carcinoembryonic Antigen Gene Maintain Its Spatiotemporal Expression Pattern (1994)

Eades-Perner, Anne-Marie, Putten, Herman Van Der, Hirth, Antje, Thompson, John A., Neumaier, Michael, Kleist, Sabine Von, ...

The tumor marker carcinoembryonic antigen (CEA) is predominantly expressed in epithelial cells along the gastrointestinal tract and in a variety of adenocarcinomas. As a basis for investigating its...

Spatiotemporal Expression of Pregnancy-Specific Glycoprotein Gene rnCGMl in Rat Placenta (1993)

Rebstock, Sabine, Lucas, Kurt, Weiss, Martina, Thompson, John A., Zimmermann, Wolfgang

As a basis towards a better understanding of the role of the pregnancy-specific glycoprotein (PSG) family in the maintenance of pregnancy, detailed investigations are described on the expression of a...

A Polymerase-chain-reaction Assay for the Specific Identification of Transcripts Encoded by Individual Carcinoembryonic Antigen (CEA)-gene-family Members (1993)

Thompson, John A., Mössinger, S., Reichhardt, V., Engels, U., Beauchemin, N., Komoss, F., ...

Carcinoembryonic antigen (CEA) is a tumor marker that belongs to a family of closely related molecules with variable expression patterns. We have developed sets of oligonucleotide primers for the...

Genomic Organization, Splice Variants and Expression of CGMl, a CD66-related Member of the Carcinoembryonic Antigen Gene Family (1993)

Nagel, Gerhard, Grunert, Fritz, Kuijpers, Taco W., Watt, Suzanne M., Thompson, John A., Zimmermann, Wolfgang

The tumor marker carcinoembryonic antigen (CEA) belongs to a family of proteins which are composed of one immunogiobulin variable domain and a varying number of immunoglobulin constant-like domains....

Ubiquitous Nuclear Factors Bind Specifically to a 5′-Region Conserved in Carcinoembryonic Antigen-Related Genes (1992)

Rudert, Fritz, Thompson, John A., Zimmermann, Wolfgang

We recently cloned members of the murine carcinoembryonic antigen (CEA) gene family, some of which are differentially expressed during placental development. By intra- and interspecies sequence...

Long-Range Chromosomal Mapping of the Carcinoembryonic Antigen (CEA) Gene Family Cluster (1992)

Thompson, John A., Zimmermann, Wolfgang, Osthus-Bugat, P., Schleussner, Cathrin, Eades-Perner, Anne-Marie, Barnert, Sabine, ...

A long-range physical map of the carcinoembryonic antigen (CEA) gene family cluster, which is located on the long arm of chromosome 19, has been constructed. This was achieved by hybridization...

Assembly and Analysis of Cosmid Contigs in the CEA-gene Family Region of Human Chromosome 19 (1992)

Tynan, Katherine, Olsen, Anne, Trask, Barbara, Jong, Pieter De, Thompson, John A., Zimmermann, Wolfgang, ...

The carcinoembryonic antigen (CEA)-like genes are members of a large gene family which Is part of the immunoglobulln superfamily. The CEA family is divided into two major subgroups, the CEA-subgroup...

Characterization of Murine Carcinoembryonic Antigen Gene Family Members (1992)

Rudert, Fritz, Saunders, Ann M., Rebstock, Sabine, Thompson, John A., Zimmermann, Wolfgang

The carcinoembryonic antigen (CEA) is a human tumor marker whose gene belongs to a family with more than 20 members. This gene family codes for a group of proteins with in vitro cell adhesion...

Carcinoembryonic Antigen Gene Family (1991)

Thompson, John A., Grunert, Fritz, Zimmermann, Wolfgang

The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin supergene family and can be divided into two main subgroups based on sequence comparisons. In humans it is clustered on...

Cloning of a Carcinoembryonic Antigen Gene Family Member Expressed in Leukocytes of Chronic Myeloid Leukemia Patients and Bone Marrow (1990)

Berling, Barbara, Kolbinger, Frank, Grunert, Fritz, Thompson, John A., Brombacher, Frank, Buchegger, Franz, ...

The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin superfamily and can be subdivided into the CEA and pregnancy-specific glycoprotein subgroups. The basic structure of the...

The Human Pregnancy-Specific Glycoprotein Genes are Tightly Linked on the Long Arm of Chromosome 19 and are Coordinately Expressed (1990)

Thompson, John A., Koumari, Rosa, Wagner, Klaus, Barnert, Sabine, Schleussner, Cathrin, Schrewe, Heinrich, ...

The pregnancy-specific glycoprotein (PSG) genes encode a group of proteins which are found in large amounts in placenta and maternal serum. In situ hybridization analyses of metaphase chromosomes...

cDNA and Gene Analyses Imply a Novel Structure for a Rat Carcinoembryonic Antigen-related Protein (1990)

Rebstock, Sabine, Lucas, Kurt, Thompson, John A., Zimmermann, Wolfgang

The gene encoding the human tumor marker carcinoembryonic antigen (CEA) belongs to a gene family which can be subdivided into the CEA and the pregnancy-specific glycoprotein subgroups. The...

Cloning of the Complete Gene for Carcinoembryonic Antigen (1990)

Schrewe, Heinrich, Thompson, John A., Bona, Marion, Hefta, Laura J. F., Maruya, Aiko, Hassauer, Martin, ...

Carcinoembryonic antigen (CEA) is a widely used tumor marker, especially in the surveillance of colonic cancer patients. Although CEA is also present in some normal tissues, it is apparently...

Identification of a Carcinoembryonic Antigen Gene Family in the Rat (1989)

Kodelja, Vitam, Lucas, Kurt, Barnert, Sabine, Kleist, Sabine Von, Thompson, John A., Zimmermann, Wolfgang

The existence of a carcinoembryonic antigen (CEA)-like gene family in rat has been demonstrated through isolation and sequencing of the N- terminal domain exons of presumably five discrete genes...

Analysis of the Size of the Carcinoembryonic Antigen (CEA) Gene Family (1989)

Thompson, John A., Mauch, Eva-Maria, Chen, Fun-Shan, Hinoda, Yuji, Schrewe, Heinrich, Berling, Barbara, ...

Five members of the human CEA gene family [human pregnancy-specific β1-glycoprotein (PSβG), hsCGM1, 2, 3 and 4] have been isolated and identified through sequencing the exons containing their...

Intra- and Interspecies Analyses of the Carcinoembryonic Antigen (CEA) Gene Family Reveal Independent Evolution in Primates and Rodents (1989)

Rudert, Fritz, Zimmermann, Wolfgang, Thompson, John A.

Various rodent and primate DNAs exhibit a stronger intra- than interspecies cross-hybridization with probes derived from the N-terminal domain exons of human and rat carcinoembryonic antigen...

cDNA Cloning Demonstrates the Expression of Pregnancy-Specific Glycoprotein Genes, a Subgroup of the Carcinoembryonic Antigen Gene Family, in Fetal Liver (1989)

Zimmermann, Wolfgang, Weiss, Martina, Thompson, John A.

The pregnancy-specific glycoprotein (PSG) genes constitute a subgroup of the carcinoembryonic antigen (CEA) gene family. Here we report the cloning of four cDNAs coding for different members of the...

The Carcinoembryonic Antigen Gene Family (1988)

Thompson, John A., Zimmermann, Wolfgang

The molecular cloning of carcinoembryonic antigen (CEA) and several cross-reacting antigens reveals a basic domain structure for the whole family, which shows structural similarities to the...

Isolation and Characterization of cDNA Clones Encoding the Human Carcinoembryonic Antigen Reveal a Highly Conserved Repeating Structure (1987)

Zimmermann, Wolfgang, Ortlieb, Barbara, Friedrich, Roland, Kleist, Sabine Von

For the isolation of cDNA clones encoding the carcinoembryonic antigen (CEA), we have constructed a cDNA library from human colon tumor mRNA. The library was screened with various oligonucleotides...

Zur Kenntnis der Glykocholie. (1947)

Zimmermann, Wolfgang.

München, Med. F., Diss. v. 21. Mai 1947 (Nicht f. d. Austausch).

Digitale Langzeitarchivierung und Recht

Goebel, Jürgen W., Scheller, Jürgen, Zimmermann, Wolfgang

Die vorliegende Arbeit wurde von den Rechtsanwälten Goebel und Scheller, Bad Homburg v.d.H. im Auftrag und mit fachlicher Betreuung durch Die Deutsche Bibliothek erstellt. Der Inhalt gibt die...

Digitale Langzeitarchivierung und Recht

Goebel, Jürgen W., Scheller, Jürgen, Zimmermann, Wolfgang

Die vorliegende Arbeit wurde von den Rechtsanwälten Goebel und Scheller, Bad Homburg v.d.H. im Auftrag und mit fachlicher Betreuung durch Die Deutsche Bibliothek erstellt. Der Inhalt gibt die...

Trophoblast Cell-Specific Carcinoembryonic Antigen Cell Adhesion Molecule 9 Is Not Required for Placental Development or a Positive Outcome of Allotypic Pregnancies

Finkenzeller, Daniela, Fischer, Beate, McLaughlin, John, Schrewe, Heinrich, Ledermann, Birgit, Zimmermann, Wolfgang

The carcinoembryonic antigen (CEA) family consists of a large group of evolutionarily divergent glycoproteins. The secreted pregnancy-specific glycoproteins constitute a subgroup within the CEA...

Genome Sequence of Bovine Herpesvirus 4, a Bovine Rhadinovirus, and Identification of an Origin of DNA Replication

Zimmermann, Wolfgang, Broll, Hermann, Ehlers, Bernhard, Buhk, Hans-Jörg, Rosenthal, André, Goltz, Michael

Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus of cattle. The complete long unique coding region (LUR) of BoHV-4 strain 66-p-347 was determined by a shotgun approach. Together with the...

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 10 Expressed Specifically Early in Pregnancy in the Decidua Is Dispensable for Normal Murine Development

Finkenzeller, Daniela, Fischer, Beate, Lutz, Sabine, Schrewe, Heinrich, Shimizu, Takehiko, Zimmermann, Wolfgang

The carcinoembryonic antigen (CEA) family consists of a large group of evolutionarily and structurally divergent glycoproteins. The murine CEACAM9 and CEACAM11-related proteins as well as the...

Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast Candida glabrata

Wong, Simon, Fares, Mario A, Zimmermann, Wolfgang, Butler, Geraldine, Wolfe, Kenneth H

Candida glabrata is a pathogenic yeast of increasing medical concern. It has been regarded as asexual but is more closely related to sexual yeasts than other Candida species. It is shown here that...

Trophoblast Cell-Specific Carcinoembryonic Antigen Cell Adhesion Molecule 9 Is Not Required for Placental Development or a Positive Outcome of Allotypic Pregnancies

Finkenzeller, Daniela, Fischer, Beate, McLaughlin, John, Schrewe, Heinrich, Ledermann, Birgit, Zimmermann, Wolfgang

The carcinoembryonic antigen (CEA) family consists of a large group of evolutionarily divergent glycoproteins. The secreted pregnancy-specific glycoproteins constitute a subgroup within the CEA...

Genome Sequence of Bovine Herpesvirus 4, a Bovine Rhadinovirus, and Identification of an Origin of DNA Replication

Zimmermann, Wolfgang, Broll, Hermann, Ehlers, Bernhard, Buhk, Hans-Jörg, Rosenthal, André, Goltz, Michael

Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus of cattle. The complete long unique coding region (LUR) of BoHV-4 strain 66-p-347 was determined by a shotgun approach. Together with the...

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 10 Expressed Specifically Early in Pregnancy in the Decidua Is Dispensable for Normal Murine Development

Finkenzeller, Daniela, Fischer, Beate, Lutz, Sabine, Schrewe, Heinrich, Shimizu, Takehiko, Zimmermann, Wolfgang

The carcinoembryonic antigen (CEA) family consists of a large group of evolutionarily and structurally divergent glycoproteins. The murine CEACAM9 and CEACAM11-related proteins as well as the...

Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast Candida glabrata

Wong, Simon, Fares, Mario A, Zimmermann, Wolfgang, Butler, Geraldine, Wolfe, Kenneth H

Candida glabrata is a pathogenic yeast of increasing medical concern. It has been regarded as asexual but is more closely related to sexual yeasts than other Candida species. It is shown here that...