Wulf Blankenfeldt

Biophysical Analysis of the Interaction of Rab6a GTPase with Its Effector Domains (2009)

Bergbrede, Tim, Chuky, Nam, Schoebel, Stefan, Blankenfeldt, Wulf, Geyer, Matthias, Fuchs, Evelyn, ...

Analysis of the eukaryotic prenylome by isoprenoid affinity tagging (2009)

Nguyen, Uyen T. T., Guo, Zhong, Delon, Christine, Wu, Yaowen, Deraeve, Celine, Fränzel, Benjamin, ...

Of Two Make One: The Biosynthesis of Phenazines (2009)

Mentel, Matthias, Ahuja, Ekta G., Mavrodi, Dmitri V., Breinbauer, Rolf, Thomashow, Linda S., Blankenfeldt, Wulf

The Active Site of an Enzyme Can Host Both Enantiomers of a Racemic Ligand Simultaneously (2009)

Mentel, Matthias, Blankenfeldt, Wulf, Breinbauer, Rolf

Gleichzeitige Bindung beider Enantiomere eines racemischen Wirkstoffs durch das aktive Zentrum eines Enzyms (2009)

Mentel, Matthias, Blankenfeldt, Wulf, Breinbauer, Rolf

Development of Selective RabGGTase Inhibitors and Crystal Structure of a RabGGTase-Inhibitor Complex (2008)

Guo, Zhong, Wu, Yao-Wen, Tan, Kui-Thong, Bon, Robin S., Guiu Rozas, Ester, Delon, Christine, ...

Development of Selective RabGGTase Inhibitors and Crystal Structure of a RabGGTase-Inhibitor Complex (2008)

Guo, Zhong, Wu, Yao-Wen, Tan, Kui-Thong, Bon, Robin S., Guiu-Rozas, Ester, Delon, Christine, ...

Biosynthesis and regulation of phenazine compounds in Pseudomonas spp. (2008)

Mavrodi, Dmitri V., Thomashow, Linda S., Blankenfeldt, Wulf

Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation (2008)

Guo, Zhong, Wu, Yao-Wen, Das, Debapratim, Delon, Christine, Cramer, Janina, Yu, Shen, ...

PhzA/B Catalyzes the Formation of the Tricycle in Phenazine Biosynthesis (2008)

Ahuja, Ekta G., Janning, Petra, Mentel, Matthias, Graebsch, Almut, Breinbauer, Rolf, Hiller, Wolf, ...

Noncompaction of the Ventricular Myocardium Is Associated with a De Novo Mutation in the β-Myosin Heavy Chain Gene (2007)

Budde, Birgit S., Binner, Priska, Waldmüller, Stephan, Höhne, Wolfgang, Blankenfeldt, Wulf, Hassfeld, Sabine, ...

The purification, crystallization and preliminary structural characterization of human MAWDBP, a member of the phenazine biosynthesis-like protein family (2006)

Herde, Petra, Blankenfeldt, Wulf

Phenazine Compounds in Fluorescent Pseudomonas Spp. Biosynthesis and Regulation (2006)

Mavrodi, Dmitri V., Blankenfeldt, Wulf, Thomashow, Linda S.

Crystal Structures of Chloroperoxidase with Its Bound Substrates and Complexed with Formate, Acetate, and Nitrate (2006)

Kühnel, Karin, Blankenfeldt, Wulf, Terner, James, Schlichting, Ilme

The purification, crystallization and preliminary structural characterization of PhzM, a phenazine-modifying methyltransferase from Pseudomonas aeruginosa (2006)

Gohain, Neelakshi, Thomashow, Linda S., Mavrodi, Dimitri V., Blankenfeldt, Wulf

Crystal structures of human cardiac β-myosin II S2-Δ provide insight into the functional role of the S2 subfragment (2006)

Blankenfeldt, Wulf, Thomä, Nicolas H., Wray, John S., Gautel, Mathias, Schlichting, Ilme

The purification, crystallization and preliminary structural characterization of FAD-dependent monooxygenase PhzS, a phenazine-modifying enzyme from Pseudomonas aeruginosa (2006)

Gohain, Neelakshi, Thomashow, Linda S., Mavrodi, Dmitri V., Blankenfeldt, Wulf

The purification, crystallization and preliminary structural characterization of FAD-dependent monooxygenase PhzS, a phenazine-modifying enzyme from Pseudomonas aeruginosa. (2006)

Gohain, Neelakshi, Thomashow, Linda S., Mavrodi, Dmitri V., Blankenfeldt, Wulf

Crystal structures of human cardiac beta−myosin II S2−{Delta} provide insight into the functional role of the S2 subfragment (2006)

Blankenfeldt, Wulf, Thomae, Nicolas H., Wray, John, Gautel, Mathias, Schlichting, Ilme

Myosin II is the major component of the muscle thick filament. It consists of two N−terminal S1 subfragments (heads) connected to a long dimeric coiled−coil rod. The rod is in itself twofold...

Crystal structures of chloroperoxidase with its bound substrates and complexed with formate, acetate and nitrate (2006)

Kühnel, Karin, Blankenfeldt, Wulf, Terner, James, Schlichting, Ilme

Chloroperoxidase (CPO) is a heme−thiolate enzyme catalyzing hydrogen peroxide dependent halogenation reactions. Structural data on substrate binding have not been available so far. CPO was...

Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens (2004)

Blankenfeldt,Wulf, Kuzin,Alexandre P., Skarina,Tatiana, Korniyenko,Yuriy, Tong,Liang, Bayer,Peter, ...

Overexpression, purification and crystallization of PhzA, the first enzyme of the phenazine biosynthesis pathway of Pseudomonas fluorescens 2-79 (2004)

Ahuja,Ekta G., Mavrodi,Dimitri V., Thomashow,Linda S., Blankenfeldt,Wulf

The purification, crystallization and preliminary structural characterization of PhzF, a key enzyme in the phenazine-biosynthesis pathway from Pseudomonas fluorescens 2-79 (2004)

Mavrodi,Dmitri V., Bleimling,Nathalie, Thomashow,Linda S., Blankenfeldt,Wulf

The purification, crystallization and preliminary structural characterization of PhzF, a key enzyme in the phenazine-biosynthesis pathway from Pseudomonas fluorescens 2-79 (2004)

Mavrodi, Dmitri V., Bleimling, Nathalie, Thomashow, Linda S., Blankenfeldt, Wulf

Overexpression, purification and crystallization of PhzA, the first enzyme of the phenazine biosynthesis pathway of Pseudomonas fluorescens 2-79 (2004)

Ahuja, Ekta G., Mavrodi, Dimitri V., Thomashow, Linda S., Blankenfeldt, Wulf

Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens (2004)

Blankenfeldt, Wulf, Kuzin, Alexandre P., Skarina, Tatiana, Korniyenko, Yuriy, Tong, Liang, Bayer, Peter, ...

Röntgenstrukturanalyse der Tyrosin-Aminotransferase aus Trypanosoma cruzi bei 2.5 Å Auflösung [Elektronische Ressource] / (1999)

Blankenfeldt, Wulf.

Braunschweig, Techn. Univ., Diss., 1999.

Röntgenstrukturanalyse der Tyrosin-Aminotransferase aus Trypanosoma cruzi bei 2.5 Ã Auflösung / (1999)

Blankenfeldt, Wulf.

Braunschweig, Techn. Univ., Diss., 1999.

Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein

Kerr, Iain D., Wadsworth, Ross I.M., Cubeddu, Liza, Blankenfeldt, Wulf, Naismith, James H., White, Malcolm F.

Information processing pathways such as DNA replication are conserved in eukaryotes and archaea and are significantly different from those found in bacteria. Single-stranded DNA-binding (SSB)...

The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (RmlA)

Blankenfeldt, Wulf, Asuncion, Miryam, Lam, Joseph S., Naismith, James H.

The synthesis of deoxy-thymidine di-phosphate (dTDP)–l-rhamnose, an important component of the cell wall of many microorganisms, is a target for therapeutic intervention. The first enzyme in the...

Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens

Blankenfeldt, Wulf, Kuzin, Alexandre P., Skarina, Tatiana, Korniyenko, Yuriy, Tong, Liang, Bayer, Peter, ...

Phenazines produced by Pseudomonas and Streptomyces spp. are heterocyclic nitrogen-containing metabolites with antibiotic, antitumor, and antiparasitic activity. The antibiotic properties of...

Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein

Kerr, Iain D., Wadsworth, Ross I.M., Cubeddu, Liza, Blankenfeldt, Wulf, Naismith, James H., White, Malcolm F.

Information processing pathways such as DNA replication are conserved in eukaryotes and archaea and are significantly different from those found in bacteria. Single-stranded DNA-binding (SSB)...

The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (RmlA)

Blankenfeldt, Wulf, Asuncion, Miryam, Lam, Joseph S., Naismith, James H.

The synthesis of deoxy-thymidine di-phosphate (dTDP)–l-rhamnose, an important component of the cell wall of many microorganisms, is a target for therapeutic intervention. The first enzyme in the...

Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens

Blankenfeldt, Wulf, Kuzin, Alexandre P., Skarina, Tatiana, Korniyenko, Yuriy, Tong, Liang, Bayer, Peter, ...

Phenazines produced by Pseudomonas and Streptomyces spp. are heterocyclic nitrogen-containing metabolites with antibiotic, antitumor, and antiparasitic activity. The antibiotic properties of...

Crystal structures of human cardiac β-myosin II S2-Δ provide insight into the functional role of the S2 subfragment

Blankenfeldt, Wulf, Thomä, Nicolas H., Wray, John S., Gautel, Mathias, Schlichting, Ilme

Myosin II is the major component of the muscle thick filament. It consists of two N-terminal S1 subfragments (“heads”) connected to a long dimeric coiled-coil rod. The rod is in itself twofold...

Noncompaction of the Ventricular Myocardium Is Associated with a De Novo Mutation in the β-Myosin Heavy Chain Gene

Budde, Birgit S., Binner, Priska, Waldmüller, Stephan, Höhne, Wolfgang, Blankenfeldt, Wulf, Hassfeld, Sabine, ...

Noncompaction of the ventricular myocardium (NVM) is the morphological hallmark of a rare familial or sporadic unclassified heart disease of heterogeneous origin. NVM results presumably from a...

The purification, crystallization and preliminary structural characterization of human MAWDBP, a member of the phenazine biosynthesis-like protein family

Herde, Petra, Blankenfeldt, Wulf

The purification, crystallization and preliminary structural characterization of human MAWD-binding protein (MAWDBP) are described.

The purification, crystallization and preliminary structural characterization of PhzM, a phenazine-modifying methyltransferase from Pseudomonas aeruginosa

Gohain, Neelakshi, Thomashow, Linda S., Mavrodi, Dmitri V., Blankenfeldt, Wulf

PhzM, an S-adenosylmethionine-dependent methyltransferase enzyme that catalyzes a reaction involved in the biosynthesis of pyocyanin in P. aeruginosa, was cloned, overexpressed and crystallized. Data...

The purification, crystallization and preliminary structural characterization of FAD-dependent monooxygenase PhzS, a phenazine-modifying enzyme from Pseudomonas aeruginosa

Gohain, Neelakshi, Thomashow, Linda S., Mavrodi, Dmitri V., Blankenfeldt, Wulf

PhzS, an FAD-dependent monooxygenase that catalyzes a reaction involved in the biosynthesis of the virulence factor pyocyanin in P. aeruginosa, was cloned, overexpressed and crystallized. Data...

Structures of RabGGTase–substrate/product complexes provide insights into the evolution of protein prenylation

Guo, Zhong, Wu, Yao-Wen, Das, Debapratim, Delon, Christine, Cramer, Janinna, Yu, Shen, ...

Post-translational isoprenylation of proteins is carried out by three related enzymes: farnesyltransferase, geranylgeranyl transferase-I, and Rab geranylgeranyl transferase (RabGGTase). Despite the...