X. Zhu

Publication List Details

Period

1987 - 2009

Number

240

Co-Authors

A multiple loop feedback Gm-C bandpass filter for wavelet transform implementation. (2009)

Zhao, W., Sun, Y., Zhu, X., He, Y.

“This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons...

Game coloring number of Cartesian product graphs (2008)

X. Zhu

Definition(s): Two person game on a graph G is played where players alternate turns in which they mark a (previously unmarked) vertex of G. Given a natural number k, the goal of the first player is...

Abstract An Architecture and Initial Performance Data for a JAVA-based Distance Education System (2008)

K. Maly, H. Abdel-wahab, C. Wild, C. M. Overstreet, A. Gupta, A. Abdel Hamid, ...

We describe our motivation and vision for a reimplementation of our Interactive Remote Instruction (IRI) system that supports synchronous and asynchronous distance education. The new version is coded...

Pacific Symposium on Biocomputing 9:152-163(2004) HAPLOTYPE BLOCK DEFINITION AND ITS APPLICATION (2008)

X. Zhu, S. Zhang, D. Kan, R. Cooper, X. Zhu, S. Zhang, ...

We present a simple two-stage procedure to define haplotype blocks and construct a statistic to test whether a polymorphism belongs to a block. Applying this method to the data of Gabriel et al....

Interdecadal variability of the Meridional Overturning Circulation as an ocean internal mode (2008)

Zhu, X., Jungclaus, J. H.

The meridional overturning circulation (MOC) in the coupled ECHAM5/MPIOM exhibits variability at periods of near 30 years and near 60 years. The 30-year variability, referred to as interdecadal...

Alzheimer's disease: Cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies (2008)

Marlatt, M.W., Lucassen, P.J., Perry, G., Smith, M.A., Zhu, X.

Many lines of independent research have provided convergent evidence regarding oxidative stress, cerebrovascular disease, dementia, and Alzheimer's disease (AD). Clinical studies spurred by these...

Low-distortion low-voltage operational transconductance amplifier. (2008)

Zhu, X., Sun, Y.

“This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons...

Analyzing the impact of direct subsidies on the performance of the Greek olive farms with a non-monotonic efficiency effects model (2008)

Zhu, X., Karagiannis, G.

We analyse the impacts of the CAP reforms on technical efficiency of Greek olive farms. We use a production frontier function and a non-monotonic inefficiency effects model which incorporates the...

Modelling land use and land cover change in the Strzelecki Ranges (2007)

Zhang, Zhenyu, Peterson, Jim, Zhu, X., Wright, Wendy

Land use and land cover change (LUCC) has been recognized as an important driver of environmental change on all spatial and temporal scales (Turner et al., 1994). LUCC contributes significantly to...

The Analysis of a New Class of Unbalanced CAST Ciphers (2007)

X. Zhu, Howard M. Heys

The original CAST cipher is an efficient and secure private-key block cipher designed to be an alternative to DES. In this paper, we present a new class of unbalanced CAST ciphers which employ the...

An approach to Hedetniemi's conjecture N.W.Sauer (2007)

X. Zhu

For a xed integer n 2!, a graph G of chromatic number greater than n is called persistent if for all n + 1-chromatic graphs H, the products G H are n + 1-chromatic graphs. Whether all graphs of...

*a (2007)

J. Shepherd, X. Zhu, N. Megiddo

This paper describes a snapshot of work in progress on the development of an efficient file-access method for similarity searching in high-dimensional vector spaces. This method has applications in,...

The effect of partonic wind on charm quark correlations in high-energy nuclear collisions (2007)

Zhu, X., Xu, N., Zhuang, P.

In high-energy collisions, massive heavy quarks are produced back-to-back initially and they are sensitive to early dynamical conditions. The strong collective partonic wind from the fast expanding...

Micro-molded cannulae for intracochlear infusions in small rodents (2007)

Johnson, Dean, Zhu, X., Frisina, Robert D., Borkholder, David

This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying...

Precision Measurement of the Neutron Spin Asymmetries and Spin-dependent Structure Functions in the Valence Quark Region (2007)

Zheng, X., Aniol, K., S. Armstrong, D., D. Averett, T., Bertozzi, W., Binet, S., ...

We report on measurements of the neutron spin asymmetries $A_{1,2}^n$ and polarized structure functions $g_{1,2}^n$ at three kinematics in the deep inelastic region, with $x=0.33$, 0.47 and 0.60 and...

Modelling land use and land cover change in the Strzelecki Ranges (2007)

Zhang, Zhenyu, Peterson, Jim, Zhu, X., Wright, Wendy

Land use and land cover change (LUCC) has been recognized as an important driver of environmental change on all spatial and temporal scales (Turner et al., 1994). LUCC contributes significantly to...

DDbar Correlations probing Thermalization in High-Energy Nuclear Collisions (2006)

Schweda, K., Zhu, X., Bleicher, M., Huang, S. L., Stoecker, H., Xu, N., ...

We propose to measure azimuthal correlations of heavy-flavor hadrons to address the status of thermalization at the partonic stage of light quarks and gluons in high-energy nuclear collisions. In...

D-Dbar Correlations as a sensitive probe for thermalization in high-energy nuclear collisions (2006)

Zhu, X., Bleicher, M., Huang, S. L., Schweda, K., Stoecker, H., Xu, N., ...

We propose to measure azimuthal correlations of heavy-flavor hadrons to address the status of thermalization at the partonic stage of light quarks and gluons in high-energy nuclear collisions. In...

Hypernuclear spectroscopy using the (e,e'K+) reaction (2006)

Yuan, L., Sarsour, M., Miyoshi, T., Zhu, X., Ahmidouch, A., Androic, D., ...

Also archived at: arXiv:nucl-ex/0408011 v1 10 Aug 2004 / The date stated on this paper is incorrect.

Hypernuclear spectroscopy using the (e,e'K+) reaction (2006)

Yuan, L., Sarsour, M., Miyoshi, T., Zhu, X., Ahmidouch, A., Androic, D., ...

Also archived at: arXiv:nucl-ex/0408011 v1 10 Aug 2004 / The date stated on this paper is incorrect.

Anisotropic flow at RHIC: How unique is the number-of-constituent-quark scaling? (2006)

Lu, Y., Bleicher, M., Liu, F., Liu, Z., Petersen, H., Sorensen, P., ...

The transverse momentum dependence of the anisotropic flow $v_2$ for $\pi$, $K$, nucleon, $\Lambda$, $\Xi$ and $\Omega$ is studied for Au+Au collisions at $\sqrt{s_{\rm NN}} = 200$ GeV within two...

Economic approach to environmental sustainability of protein foods (2006)

Zhu, X.

Intensive animal production systems in Europe, particularly in the Netherlands result in a series of environmental problems mainly due to manure surplus. This study aims to make contributions to...

Impacts of Novel Protein Foods on Sustainable Food Production and Consumption: Lifestyle Change and Environmental Policy (2006)

Zhu, X.

We analyse the impacts of a change in consumers¿ preference for Novel Protein Foods (NPFs), i.e. a lifestyle change with respect to meat consumption, and the impacts of environmental policies e.g....

The enlargement of the European Union: Effects on trade and emissions of greenhouse gases (2006)

Zhu, X.

With the gradual accession of various Central and Eastern European Countries (CEECs) to the European Union (EU), international trade between the EU and the CEECs will change as a result of trade...

Variability regimes of simulated Atlantic MOC (2006)

Zhu, X., Fraedrich, K., Blender, R.

The spectral variability structure of the meridional overturning circulation (MOC) of the Atlantic Ocean is determined in 500 year simulations with state-of-the-art coupled atmosphere-ocean general...

Comparison of Several Eco-Friendly Refrigeration Technologies (2006)

Tang, C., Luo, Q., Li, X., Zhu, X.

In this paper, the operation principles, thermodynamics characteristics, and technical practicability were compared between thermoelectric refrigeration, magnetic refrigeration and adsorption...

Expression of Tim-3 is transiently increased before increased before development of anterior chamber-associated immune deviation. (2006)

Wang, Y., Yang, P., Li, B., Zhou, H., Huang, X., Wang, Y., ...

To assess the expression of T-cell immunoglobulin- and mucin-domain-containing molecule 3 (Tim-3) in the spleens of BALB/c mice undergoing anterior chamber-associated immune deviation (ACAID)....

Crystal structure of mouse succinic semialdehyde reductase AKR7A5: structural basis for substrate specificity (2006)

Zhu, X., Lapthorn, A.J., Ellis, E.

The aldo-keto reductases make up a superfamily of enzymes which can reduce a variety of aldehydes and ketones to their corresponding alcohols. Within each family are distinct preferences for certain...

Comparison of Several Eco-Friendly Refrigeration Technologies (2006)

Tang, C., Luo, Q., Li, X., Zhu, X.

In this paper, the operation principles, thermodynamics characteristics, and technical practicability were compared between thermoelectric refrigeration, magnetic refrigeration and adsorption...

Crystal structure of mouse succinic semialdehyde reductase AKR7A5: structural basis for substrate specificity (2006)

Zhu, X., Lapthorn, A.J., Ellis, E.

The aldo-keto reductases make up a superfamily of enzymes which can reduce a variety of aldehydes and ketones to their corresponding alcohols. Within each family are distinct preferences for certain...

Crystal structure of mouse succinic semialdehyde reductase AKR7A5: structural basis for substrate specificity (2006)

Zhu, X., Lapthorn, A.J., Ellis, E.

The aldo-keto reductases make up a superfamily of enzymes which can reduce a variety of aldehydes and ketones to their corresponding alcohols. Within each family are distinct preferences for certain...

Implementation of a GMPLS-based network with end host initiated signaling (2006)

X. Zhu, X. Zheng, M. Veeraraghavan, Z. Li, Q. Song

Abstract 1-- In this article, we describe our experiences in implementing an experimental wide-area GMPLS network called CHEE-TAH (Circuit-Switched End-to-End Transport Architecture). The key concept...

Appl Intell DOI 10.1007/s10489-006-0032-0 Semi-parametric optimization for missing data imputation (2006)

Yongsong Qin, Shichao Zhang, Xiaofeng Zhu, Jilian Zhang, Chengqi Zhang, S. Zhang, ...

Abstract Missing data imputation is an important issue in machine learning and data mining. In this paper, we propose a new and efficient imputation method for a kind of missing data: semi-parametric...

Implementation of a GMPLS-based network with end host initiated signaling (2006)

X. Zhu, X. Zheng, M. Veeraraghavan, Z. Li, Q. Song

Abstract 1-- In this article, we describe our experiences in implementing an experimental wide-area GMPLS network called CHEE-TAH (Circuit-Switched End-to-End Transport Architecture). The key concept...

Universal characteristics and function-control of nanostructured materials. (2006)

Yamazaki, Y., Ou-Yang, Z.C., Iwamoto, M., Gleiter, H., Zhu, X., Zhang, Z.H., ...

Proc. of the Int. Symp. on the Manipulation of Advanced Smart Materials 2005 (ISMASM 2005), Nara, J, May 26-27, 2005

Efficiency, Robustness and Stochasticity of Gene Regulatory Networks in Systems Biology: lambda Switch as a Working Example (2005)

Zhu, X., Yin, L., Hood, L., Galas, D., Ao, P.

Phage lambda is one of the most studied biological models in modern molecular biology. Over the past 50 years quantitative experimental knowledge on this biological model has been accumulated at all...

The Q$^2$-Dependence of the Neutron Spin Structure Function g$_2^n$ at Low Q$^2$ (2005)

Kramer, K., Armstrong, D., Averett, T., Bertozzi, W., Binet, S., Butuceanu, C., ...

We present the first measurement of the Q^2-dependence of the neutron spin structure function g_2^n at five kinematic points covering 0.57 (GeV/c)^2

Transverse Pressure and Strangeness Dynamics in Relativistic Heavy Ion Reactions (2005)

Bleicher, M., Bratkovskaya, E., Vogel, S., Zhu, X.

Transverse hadron spectra from proton-proton, proton-nucleus and nucleus-nucleus collisions from 2 AGeV to 21.3 ATeV are investigated within two independent transport approaches (HSD and UrQMD). For...

Programming style based program partition (2005)

Yang, Hongji, Cheng, X., Li, Y., Zhu, X.

Traditional program partitioning methods are nonlinear, and their computational efforts increase exponentially with the size of the source program. The NP-hard complexity constitutes a computational...

Programming style based program partition (2005)

Yang, Hongji, Cheng, X., Li, Y., Zhu, X.

Traditional program partitioning methods are nonlinear, and their computational efforts increase exponentially with the size of the source program. The NP-hard complexity constitutes a computational...

Discounting and environmental quality: When should dual rates be used? (2005)

Weikard, H.P., Zhu, X.

Triggered by concerns about impacts of long-run climatic change the use of dual-rate discounting to evaluate projects and policies has been suggested. Environmental goods should be discounted at a...

A model for consumers' preferences for Novel Protein Foods and environmental quality (2005)

Zhu, X.

We develop an environmental Applied General Equilibrium (AGE) model, which includes the economic functions of the environment, to investigate the impacts of consumers' preference changes towards the...

Modelling consumers' preferences for Novel Protein Foods and environmental quality (2005)

Zhu, X.

We develop a theoretical Applied General Equilibrium (AGE) model that explicitly includes the environmental input in production functions and the consumers' preferences for environmental quality in...

The Q$^2$-Dependence of the Neutron Spin Structure Function g$_2^n$ at Low Q$^2$ (2005)

Kramer, K., Armstrong, D., Averett, T., Bertozzi, W., Binet, S., Butuceanu, C., ...

We present the first measurement of the Q^2-dependence of the neutron spin structure function g_2^n at five kinematic points covering 0.57 (GeV/c)^2

The Q$^2$-Dependence of the Neutron Spin Structure Function g$_2^n$ at Low Q$^2$ (2005)

Kramer, K., Armstrong, D., Averett, T., Bertozzi, W., Binet, S., Butuceanu, C., ...

We present the first measurement of the Q^2-dependence of the neutron spin structure function g_2^n at five kinematic points covering 0.57 (GeV/c)^2

Age-related hearing research (2005)

Snell, KB, Frisina, DR, Zettel, ML, O'Neill, WE, Trang, TT, Frisina, RD, ...

To request individual papers in any of the sections, please include the full citation and the AN number found in brackets at the end of the citation. Contact the Department of Educational Resources...

Age-related hearing research (2005)

Snell, K., Frisina, D. Robert, Zettel, M., O'Neill, W., Trang, T., Frisina, Robert D., ...

To request individual papers in any of the sections, please include the full citation and the AN number found in brackets at the end of the citation. Contact the Department of Educational Resources...

Learning and teaching in Chinese higher education (2005)

Sharma, Raj, Zhu, X.

WTO has turned the world into a global village. Countries trade and visit each other freely. Local economy affects national and even global economy. People of high English language (de facto the...

Learning and teaching in Chinese higher education (2005)

Sharma, Raj, Zhu, X.

WTO has turned the world into a global village. Countries trade and visit each other freely. Local economy affects national and even global economy. People of high English language (de facto the...

Amino acid analysis by micellar electrokinetic chromatography with laser-induced fluorescence detection: Application to nanolitre-volume biological samples from Arabidopsis thaliana and Myzus persicae (2005)

Zhu, X., Shaw, P. N., Pritchard, J., Newbury, J., Hunt, E. J., Barrett, D. A.

Amino acids were derivatised with 4-fluoro-7-nitrobenzo-2,1,3-oxadiazoI (NBID-F), separated by micellar electrokinetic chromatography (MEKC), and detected by argonion (488 nm) laser-induced...

Learning and teaching in Chinese higher education (2005)

Sharma, Raj, Zhu, X.

WTO has turned the world into a global village. Countries trade and visit each other freely. Local economy affects national and even global economy. People of high English language (de facto the...

A self-consistent derivation of ion drag and Joule heating for atmospheric dynamics in the thermosphere (2005)

Zhu, X., Talaat, E. R., Baker, J. B. H.

The thermosphere is subject to additional electric and magnetic forces, not important in the middle and lower atmosphere, due to its partially ionized atmosphere. The effects of charged particles on...

A self-consistent derivation of ion drag and Joule heating for atmospheric dynamics in the thermosphere (2005)

Zhu, X., Talaat, E. R., Baker, J. B. H.

The thermosphere is subject to additional electric and magnetic forces, not important in the middle and lower atmosphere, due to its partially ionized atmosphere. The effects of charged particles on...

Learning and teaching in Chinese higher education (2005)

Sharma, Raj, Zhu, X.

WTO has turned the world into a global village. Countries trade and visit each other freely. Local economy affects national and even global economy. People of high English language (de facto the...

Amino acid analysis by micellar electrokinetic chromatography with laser-induced fluorescence detection: Application to nanolitre-volume biological samples from Arabidopsis thaliana and Myzus persicae (2005)

Zhu, X., Shaw, P. N., Pritchard, J., Newbury, J., Hunt, E. J., Barrett, D. A.

Amino acids were derivatised with 4-fluoro-7-nitrobenzo-2,1,3-oxadiazoI (NBID-F), separated by micellar electrokinetic chromatography (MEKC), and detected by argonion (488 nm) laser-induced...

Adaptive entitlement control of resource containers on shared servers (2005)

X. Liu, X. Zhu, S. Singhal, M. Arlitt

In this paper, we describe the design of online feedback control algorithms to dynamically adjust entitlement values for a resource container on a server shared by multiple applications. The goal is...

Adaptive entitlement control of resource containers on shared servers (2005)

X. Liu, X. Zhu, S. Singhal, M. Arlitt

In this paper, we describe the design of online feedback control algorithms to dynamically adjust entitlement values for a resource container on a server shared by multiple applications. The goal is...

Learning and teaching in Chinese higher education (2005)

Sharma, Raj, Zhu, X.

WTO has turned the world into a global village. Countries trade and visit each other freely. Local economy affects national and even global economy. People of high English language (de facto the...

Nonequilibrium Models of Relativistic Heavy-Ion Collisions (2004)

Stoecker, H., Bratkovskaya, E. L., Bleicher, M., Soff, S., Zhu, X.

We review the results from the various hydrodynamical and transport models on the collective flow observables from AGS to RHIC energies. A critical discussion of the present status of the CERN...

Compensatory growth and food consumption in gibel carp, Carassius auratus givelio, and Chinese longsnout catfish, Leiocassis longirostris, experiencing cycles of feed deprivation and re-feeding (2004)

Zhu, X., Xie, S., Zou, Z., Wu, L., Cui, Y., Yang, Y., ...

The compensatory responses of juvenile gibel carp and Chinese longsnout catfish to four cycles of 1 week of feed deprivation and 2 weeks of satiation feeding were quantified as part of a study...

Introducing Novel Protein Foods in the EU: Economic and Environmental Impacts (2004)

Zhu, X., Wesseler, J.H.H.

Production of traditional animal protein products has high environmental impacts. Introducing Novel Protein Foods (NPFs) to the European Union (EU) is supposed to be one of the choices of reducing...

The relational grid monitoring architecture: Mediating information about the grid (2004)

A. W. Cooke, W. Nutt, J. Magowan, M. Oevers, P. Taylor, ...

Abstract. We have developed and implemented the Relational Grid Monitoring Architecture (R-GMA) as part of the DataGrid project, to provide a flexible information and monitoring service for use by...

The relational grid monitoring architecture: Mediating information about the grid (2004)

A. W. Cooke, W. Nutt, J. Magowan, M. Oevers, P. Taylor, ...

Abstract. We have developed and implemented the Relational Grid Monitoring Architecture (R-GMA) as part of the DataGrid project, to provide a flexible information and monitoring service for use by...

Mesoscopic phase transition of nanostructured materials: construction of computer experimental systems and synthesis and control of functional properties. (2004)

Yamazaki, Y., Gleiter, H., Lu, K., Ou-Yang, Z.C., Zhu, X.

German-Chinese Workshop on Fundamentals and Applications of Nanoscience: Building Blocks, Modelling and Structuring, July 1-4, 2002

Mesoscopic phases and characteristics of nano-structured interfaces. (2004)

Yamazaki, Y., Gleiter, H., Ou-Yang, Z.C., Zhu, X., Zhang, Z., Shi, Q.F., ...

Chinese-German Forum on Fundamentals and Technological Perspectives of Nanoscience, Beijing, China, September 26-30, 2004

Towards a systems engineering pattern language: Applying i* model requirements-architecture patterns (2003)

P. Pavan, X. Zhu

This paper reports the results of exploratory research to develop a pilot pattern language for systems engineers at BAE SYSTEMS. The pattern language was designed to encapsulate knowledge about...

High-speed rail operations on an existing network: an assessment model for China (2002)

Wong, Wing-gun, Han, B.M., Ferreira, Luis, Zhu, X.

High-speed rail operations have the potential to reduce the long-term decline in rail passenger travel demand for the medium to long distance inter-urban markets. Such decline has been evident...

High-speed rail operations on an existing network: an assessment model for China (2002)

Wong, W.G., Han, B.M., Ferreira, Luis, Zhu, X.

High-speed rail operations have the potential to reduce the long-term decline in rail passenger travel demand for the medium to long distance inter-urban markets. Such decline has been evident...

High-speed rail operations on an existing network: an assessment model for China (2002)

Wong, W.G., Han, B.M., Ferreira, Luis, Zhu, X.

High-speed rail operations have the potential to reduce the long-term decline in rail passenger travel demand for the medium to long distance inter-urban markets. Such decline has been evident...

Location of Pc 1?2 waves relative to the magnetopause (2002)

Denton, R. E., Labelle, J., Zhu, X.

Spacecraft-borne and ground-based magnetometers frequently detect magnetospheric micropulsations in the period range 0.2?10 s, termed Pc 1?2, and attributed to electromagnetic ion cyclotron waves...

Location of Pc 1?2 waves relative to the magnetopause (2002)

Denton, R. E., Labelle, J., Zhu, X.

Spacecraft-borne and ground-based magnetometers frequently detect magnetospheric micropulsations in the period range 0.2?10 s, termed Pc 1?2, and attributed to electromagnetic ion cyclotron waves...

High-speed rail operations on an existing network: an assessment model for China (2002)

Wong, Wing-gun, Han, B.M., Ferreira, Luis, Zhu, X.

High-speed rail operations have the potential to reduce the long-term decline in rail passenger travel demand for the medium to long distance inter-urban markets. Such decline has been evident...

High-speed rail operations on an existing network: an assessment model for China (2002)

Wong, Wing-gun, Han, B.M., Ferreira, Luis, Zhu, X.

High-speed rail operations have the potential to reduce the long-term decline in rail passenger travel demand for the medium to long distance inter-urban markets. Such decline has been evident...

High-speed rail operations on an existing network: an assessment model for China (2002)

Wong, Wing-gun, Han, B.M., Ferreira, Luis, Zhu, X.

High-speed rail operations have the potential to reduce the long-term decline in rail passenger travel demand for the medium to long distance inter-urban markets. Such decline has been evident...

High-speed rail operations on an existing network: an assessment model for China (2002)

Wong, Wing-gun, Han, B.M., Ferreira, Luis, Zhu, X.

High-speed rail operations have the potential to reduce the long-term decline in rail passenger travel demand for the medium to long distance inter-urban markets. Such decline has been evident...

High-speed rail operations on an existing network: an assessment model for China (2002)

Wong, Wing-gun, Han, B.M., Ferreira, Luis, Zhu, X.

High-speed rail operations have the potential to reduce the long-term decline in rail passenger travel demand for the medium to long distance inter-urban markets. Such decline has been evident...

High-speed rail operations on an existing network: an assessment model for China (2002)

Wong, Wing-gun, Han, B.M., Ferreira, Luis, Zhu, X.

High-speed rail operations have the potential to reduce the long-term decline in rail passenger travel demand for the medium to long distance inter-urban markets. Such decline has been evident...

Comparison of compensatory growth responses of juvenile three-spined stickleback and minnow following similar food deprivation protocols (2001)

Zhu, X., Cui, Y., Ali, M., Wootton, Robert J.

The compensatory growth responses of individual juveniles of two co- existing species were compared after identical periods of starvation to determine inter-specific similarities and differences. The...

Compensatory growth in the gibel carp following feed deprivation: temporal patterns in growth, nutrient deposition, feed intake and body composition (2001)

Xie, S., Zhu, X., Cui, Y., Wootton, Robert J., Lei, W., Yang, Y.

To investigate the nature of compenstory growth in fish, an 8 week study at 28°C was performed on juvenile gibel carp Carassius auratus gibelio weighing 6·6 g. Fish were starved for 0 (control), 1...

Personal Dose Monitoring of Employees at the Institute of Modern Physics, China (2001)

Wang, G., Li, S., Yao, N., Zhu, X., Li, Z., Zheng, H.

The radiation field at the accelerator facility consists of radiation produced immediately and of secondary radiation induced by activation etc. As the accelerator building and the experimental hall...

Characterization of a calcium-regulation domain of the skeletal-muscle ryanodine receptor. (2000)

Hayek, S M, Zhu, X, Bhat, M B, Zhao, J, Takeshima, H, Valdivia, H H, ...

A negatively charged region of the N-terminal portion of the skeletal ryanodine receptor (RyR), located between residues 1872-1923, is involved in Ca (2+)-dependent regulation of the Ca(2+)-release...

Stable Second-Order Optical Nonlinearity in Novel Photocrosslinkable Polymers. (1998)

Li, L., Zhu, X., Jeng, R. J., Chen, Y. M., Kumar, J.

Optical Characterization of novel photocrosslinkable second-order nonlinear optical (NLO) polymers are presented. These polymer systems have been designed with nonlinear optical moieties in the...

Comparison of a synthetic antithrombin III-binding pentasaccharide and standard heparin as an adjunct to coronary thrombolysis (1998)

Pislaru, C, Zhu, X, Stassen, T, Vanhove, P, ...

The effects on alteplase-induced thrombolysis of the synthetic ATIII-binding pentasaccharide SR90107A/ORG 31540 (synthetic pentasaccharide, SP) and of standard heparin (SH) were compared in a copper...

Charged particle production in proton-, deuteron-, oxygen- and sulphur-nucleus collisions at 200 GeV per nucleon (1998)

Alber, T, Appelshäuser, H, Bächler, J, Bartke, Jerzy, Bialkowska, H, Bloomer, M A, ...

The transverse momentum and rapidity distributions of net protons and negatively charged hadrons have been measured for minimum bias proton-nucleus and deuteron-gold interactions, as well as central...

Bacterial expression of two human aryl sulfotransferases (1998)

Bidwell, L. M., Gillam, E. M. J., Gaedigk, A., Zhu, X., Grant, D., McManus, M. E.

The effect of replacing a single codon in the N-terminal of human aryl sulfotransferase (HAST) 1 and 3 with one that is more commonly found in E. coli genes was assessed. The pKK233-2 E. coli...

Bacterial expression of two human aryl sulfotransferases (1998)

Bidwell, L. M., Gillam, E. M. J., Gaedigk, A., Zhu, X., Grant, D., McManus, M. E.

The effect of replacing a single codon in the N-terminal of human aryl sulfotransferase (HAST) 1 and 3 with one that is more commonly found in E. coli genes was assessed. The pKK233-2 E. coli...

Quasars around the Seyfert Galaxy NGC3516 (1997)

Chu, Y., Wei, J., Hu, J., Zhu, X., Arp, H.

We report redshift measurements of 5 X-ray emitting blue stellar objects (BSO's) located less than 12 arc min from the X-ray Seyfert galaxy, NGC 3516. We find these quasars to be distributed along...

Acyclic and Oriented Chromatic Numbers of Graphs (1997)

Kostochka Novosibirsk, A. V. Kostochka, E. Sopena, X. Zhu

The oriented chromatic number Ø o ( ~ G) of an oriented graph ~ G = (V; A) is the minimum number of vertices in an oriented graph ~ H for which there exists a homomorphism of ~ G to ~ H. The...

Duality and polynomial testing of tree homomorphisms (1996)

P. Hell, X. Zhu

Abstract. Let H be a fixed digraph. We consider the H-colouring problem, i.e., the problem of deciding which digraphs G admit a homomorphism to H. We are interested in a characterization in terms of...

CHEMICAL KINETICS OF THE REACTION OF METHOXY WITH MOLECULAR OXYGEN FOR VARIOUS TEMPERATURES, PRESSURES AND BUFFER $GASES, ^{\ast}$ (1995)

Misra, P., Nur, A. H., Zhu, X.

$^{\ast}$Financial support from the U.S. Environmental Protection Agency's Office of Exploratory Research (\# R819720-01-0), NASA Lewis Research Center (\# NAG3-1677) and the Center for the Study of...

DETERMINATION OF SEVERAL NEW VIBRATIONAL FREQUENCIES FOR THE ETHOXY RADICAL (1995)

Misra, P., Zhu, X., Kamal, M.

$^{\ast}$Financial support from the U.S. Environmental Protection Agency's Office of Exploratory Research (# R819720-01-0), NASA Lewis Research Center (# NAG3-1677) and the Center for the Study of...

FLUORESCENCE LIFETIMES OF LASER-EXCITED ALKOXY $RADICALS^{\ast}$ (1995)

Misra, P., Sandifor, C., Zhu, X.

$^{\ast}$Financial support from the U.S. Environmental Protection Agency's Office of Exploratory Research (# R819720-01-0), NASA Lewis Research Center (NAG3-1677) and the Center for the Study of...

Acyclic and Oriented Chromatic Numbers of Graphs (1995)

A.V. Kostochka, E. Sopena, X. Zhu

The oriented chromatic number Ø o ( ~ G) of an oriented graph ~ G = (V; A) is the minimum number of vertices in an oriented graph ~ H for which there exists a homomorphism of ~ G to ~ H. The...

VIBRATIONAL AND ROTATIONAL LASER SPECTROSCOPY OF SUPERSONICALLY COOLED ALKOXY AND ALKYLTHIO $RADICALS^{*}$ (1994)

Misra, P., Zhu, X., Kamal, M., Nur, A. H.

$^{*}$Financial support from the NASA Center for the Study of Terrestrial and Extraterrestrial Atmospheres (\# NASA NAGW-2950), U.S. Environmental Protection Agency's Office of Exploratory Research...

LASER OPTOGALVANIC TRANSITIONS OF NEON IN THE NEAR ULTRAVIOLET AND $VISIBLE^{\bullet}$ (1994)

Misra, P., Zhu, X., Nur, A. H.

$^{\bullet}$Financial support from the NASA Center for the Study of Terrestrial and Extraterrestrial Atmospheres (\# NASA NAGW-2950), U.S. Environmental Protection Agency’s Office of Exploratory...

Heterologous Systems for Expression of Mammalian Sulfotransferases (1994)

Veronese, M. E., Burgess, W., Cruickshank, D., Sansom, L., Zhu, X., McManus, M. E.

This paper describes the use of both mammalian and bacterial expression systems as tools to study the structural and functional relationships of proteins encoded by cDNAs to both rat and human aryl...

Heterologous Systems for Expression of Mammalian Sulfotransferases (1994)

Veronese, M. E., Burgess, W., Cruickshank, D., Sansom, L., Zhu, X., McManus, M. E.

This paper describes the use of both mammalian and bacterial expression systems as tools to study the structural and functional relationships of proteins encoded by cDNAs to both rat and human aryl...

On Bounded Treewidth Duality of Graphs (1994)

Jarik Nesetril, X. Zhu

We prove that for any integers m; k, there is an integer n 0 such that if G is a graph of girth n 0 then any partial k-tree homomorphic to G is also homomorphic to C 2m+1 . As a corollary, every...

Circular Coloring of Weighted Graphs (1994)

W. Deuber, X. Zhu

Suppose that G is a finite simple graph and w is a weight function which assigns to each vertex of G a nonnegative real number. Let C be a circle of length t. A t-circular coloring of (G; w) is a...

Nonlinear conductivity of a two-dimensional pinned charge-density wave in a strong magnetic field (1993)

Littlewood, P., Millis, A., Zhu, X., Normand, B.

We present the theory of the dynamics of a two-dimensional Wigner crystal in a high magnetic field, assuming charge-density-wave correlations extend over a distance large compared to the...

Nonlinear conductivity of a two-dimensional pinned charge-density wave in a strong magnetic field (1993)

Littlewood, P., Millis, A., Zhu, X., Normand, B.

We present the theory of the dynamics of a two-dimensional Wigner crystal in a high magnetic field, assuming charge-density-wave correlations extend over a distance large compared to the...

Nonlinear conductivity of a two-dimensional pinned charge-density wave in a strong magnetic field (1993)

Littlewood, P., Millis, A., Zhu, X., Normand, B.

We present the theory of the dynamics of a two-dimensional Wigner crystal in a high magnetic field, assuming charge-density-wave correlations extend over a distance large compared to the...

Identification of two human brain aryl sulfotransferase cDNAs (1993)

Zhu, X., Veronese, M. E., Bernard, C. A., Sansom, L. N., McManus, M. E.

A 1,179 bp and a 1,424 bp full-length aryl sulfotransferase cDNAs were isolated from a human brain cDNA library. Their coding domains are 93% identical, each encoding a cytosolic protein of 295 amino...

Identification of two human brain aryl sulfotransferase cDNAs (1993)

Zhu, X., Veronese, M. E., Bernard, C. A., Sansom, L. N., McManus, M. E.

A 1,179 bp and a 1,424 bp full-length aryl sulfotransferase cDNAs were isolated from a human brain cDNA library. Their coding domains are 93% identical, each encoding a cytosolic protein of 295 amino...

PARITY VIOLATION IN 239U NEUTRON RESONANCES (1990)

PenttilÄ, S., Bowman, C., Bush, J., Delheij, P., Frankle, C., Gould, C., ...

Parity nonconservation was studied in 239U by measuring the helicity dependence of the p-wave resonance cross section for epithermal neutrons scattered from 238U. A statistical approach was used to...

PARITY VIOLATION IN 239U NEUTRON RESONANCES (1990)

PenttilÄ, S., Bowman, C., Bush, J., Delheij, P., Frankle, C., Gould, C., ...

Parity nonconservation was studied in 239U by measuring the helicity dependence of the p-wave resonance cross section for epithermal neutrons scattered from 238U. A statistical approach was used to...

PARITY VIOLATION IN 239U NEUTRON RESONANCES (1990)

PenttilÄ, S., Bowman, C., Bush, J., Delheij, P., Frankle, C., Gould, C., ...

Parity nonconservation was studied in 239U by measuring the helicity dependence of the p-wave resonance cross section for epithermal neutrons scattered from 238U. A statistical approach was used to...

DETERMINATION OF PARAMETERS OF HIGH TEMPERATURE INTERNAL FRICTION FROM SINGLE EXPERIMENTAL CURVE (1987)

Jiang, Z., Zhu, X., Fan, W.

An advanced calculation has been completed by computer for studing Al and its alloys. In doing so, both parameters of grain boundary relaxation and three parameters of background internal friction...

DETERMINATION OF PARAMETERS OF HIGH TEMPERATURE INTERNAL FRICTION FROM SINGLE EXPERIMENTAL CURVE (1987)

Jiang, Z., Zhu, X., Fan, W.

An advanced calculation has been completed by computer for studing Al and its alloys. In doing so, both parameters of grain boundary relaxation and three parameters of background internal friction...

DETERMINATION OF PARAMETERS OF HIGH TEMPERATURE INTERNAL FRICTION FROM SINGLE EXPERIMENTAL CURVE (1987)

Jiang, Z., Zhu, X., Fan, W.

An advanced calculation has been completed by computer for studing Al and its alloys. In doing so, both parameters of grain boundary relaxation and three parameters of background internal friction...

Mutations in the C-terminal fragment of DnaK affecting peptide binding.

Burkholder, W F, Zhao, X, Zhu, X, Hendrickson, W A, Gragerov, A, Gottesman, M E

Escherichia coli DnaK acts as a molecular chaperone through its ATP-regulated binding and release of polypeptide substrates. Overexpressing a C-terminal fragment (CTF) of DnaK (Gly-384 to Lys-638)...

Cell cycle-dependent modulation of telomerase activity in tumor cells.

Zhu, X, Kumar, R, Mandal, M, Sharma, N, Sharma, H W, Dhingra, U, ...

Telomerase is a ribonucleoprotein complex that is thought to add telomeric repeats onto the ends of chromosomes during the replicative phase of the cell cycle. We tested this hypothesis by arresting...

Internal cleavage of the inhibitory 7B2 carboxyl-terminal peptide by PC2: a potential mechanism for its inactivation.

Zhu, X, Rouille, Y, Lamango, N S, Steiner, D F, Lindberg, I

The neuroendocrine protein 7B2 contains two domains, a 21-kDa protein required for prohormone convertase 2 (PC2) maturation and a carboxyl-terminal (CT) peptide that inhibits PC2 at nanomolar...

G protein subunits and the stimulation of phospholipase C by Gs-and Gi-coupled receptors: Lack of receptor selectivity of Galpha(16) and evidence for a synergic interaction between Gbeta gamma and the alpha subunit of a receptor activated G protein.

Zhu, X, Birnbaumer, L

Stimulatory guanine nucleotide binding protein (Gs)-coupled receptors activated by luteinizing hormone, vasopressin, and the catecholamine isoproterenol (luteinizing hormone receptor, type 2...

Cue recognition and cue elaboration in learning from examples.

Zhu, X, Lee, Y, Simon, H A, Zhu, D

This paper describes the processes used by students to learn from worked-out examples and by working through problems. Evidence is derived from protocols of students learning secondary school...

Dominant lethal mutations in the plasma membrane H(+)-ATPase gene of Saccharomyces cerevisiae.

Harris, S L, Na, S, Zhu, X, Seto-Young, D, Perlin, D S, Teem, J H, ...

The plasma membrane H(+)-ATPase of Saccharomyces cerevisiae is an essential protein that is required to establish cellular membrane potential and maintain a normal internal pH. An Asp-378 to Asn...

Efficacy of beta 1-adrenergic receptors is lower than that of beta 2-adrenergic receptors.

Levy, F O, Zhu, X, Kaumann, A J, Birnbaumer, L

We investigated the relative activity at which fully occupied human beta 1- and beta 2-adrenergic receptors (beta 1AR and beta 2AR) activate the stimulatory G protein (Gs)/adenylyl cyclase (AC)...

A myo-inositol pool utilized for phosphatidylinositol synthesis is depleted in sciatic nerve from rats with streptozotocin-induced diabetes.

Zhu, X, Eichberg, J

Peripheral nerve from experimentally diabetic rats exhibits lowered levels of myo-inositol (MI) and decreased incorporation of [3H]MI into phosphatidylinositol (PI). There are indications that...

Tyrosine 106 of CheY plays an important role in chemotaxis signal transduction in Escherichia coli.

Zhu, X, Amsler, C D, Volz, K, Matsumura, P

CheY is the response regulator in the signal transduction pathway of bacterial chemotaxis. Position 106 of CheY is occupied by a conserved aromatic residue (tyrosine or phenylalanine) in the response...

The ispB gene encoding octaprenyl diphosphate synthase is essential for growth of Escherichia coli.

Okada, K, Minehira, M, Zhu, X, Suzuki, K, Nakagawa, T, Matsuda, H, ...

The Escherichia coli ispB gene encoding octaprenyl diphosphate synthase is responsible for the synthesis of the side chain of isoprenoid quinones. We tried to construct an E. coli ispB-disrupted...

Cloning of the sdsA gene encoding solanesyl diphosphate synthase from Rhodobacter capsulatus and its functional expression in Escherichia coli and Saccharomyces cerevisiae.

Okada, K, Kamiya, Y, Zhu, X, Suzuki, K, Tanaka, K, Nakagawa, T, ...

Different organisms produce different species of isoprenoid quinones, each with its own distinctive length. These differences in length are commonly exploited in microbial classification. The side...

Cellular recombination pathways and viral terminal repeat hairpin structures are sufficient for adeno-associated virus integration in vivo and in vitro.

Yang, C C, Xiao, X, Zhu, X, Ansardi, D C, Epstein, N D, Frey, M R, ...

The human parvovirus adeno-associated virus (AAV) is unique in its ability to target viral integration to a specific site on chromosome 19 (ch-19). Recombinant AAV (rAAV) vectors retain the ability...

Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression.

Zhu, X, Mancini, M A, Chang, K H, Liu, C Y, Chen, C F, Shan, B, ...

A gene assigned to human chromosome 1q32-41 encodes a novel protein of 3,113 amino acids containing an internal tandem repeat of 177 amino acids. The protein, which we have named "mitosin," was...

Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase.

Zhu, X, Wen, Z, Xu, L Z, Darnell, J E

Gamma interferon (IFN-gamma) induces both tyrosine and serine phosphorylation of Stat1. Stat1 serine phosphorylation is required for maximal transcriptional activity of Stat1. In this report, we...

Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation.

Zhu, X, Assoian, R K

Adhesion to extracellular matrix mediates cell cycle progression in mid-late G1; this effect involves an integrin-dependent organization of the cytoskeleton and a consequent change in cell shape. In...

A simple and efficient method for site-directed mutagenesis with double-stranded plasmid DNA.

Lai, D, Zhu, X, Pestka, S

A general, simple and efficient method for preparing site-specific mutations in double-stranded plasmid DNA without the need for special plasmids, bacterial strains or reagents is described. Only one...

Studies on the intrinsic activity (efficacy) of human adrenergic receptors. Co-expression of beta 1 and beta 2 reveals a lower efficacy for the beta 1 receptor.

Birnbaumer, L, Levy, F O, Zhu, X, Kaumann, A J

Through co-expression of the human beta 1 and beta 2 adrenergic receptors in a single tester cell (the murine L fibroblast) and through assaying the effect of the beta 1 and beta 2 selective blockers...

Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F.

Shan, B, Zhu, X, Chen, P L, Durfee, T, Yang, Y, Sharp, D, ...

The retinoblastoma protein interacts with a number of cellular proteins to form complexes which are probably crucial for its normal physiological function. To identify these proteins, we isolated...

Mutations in the RB1 gene and their effects on transcription.

Dunn, J M, Phillips, R A, Zhu, X, Becker, A, Gallie, B L

Inactivation of both alleles of the RB1 gene during normal retinal development initiates the formation of a retinoblastoma (RB) tumor. To identify the mutations which inactivate RB1, 21 RB tumors...

Catalytic residues of gamma delta resolvase act in cis.

Boocock, M R, Zhu, X, Grindley, N D

The resolvase protein of the gamma delta transposon is a site-specific recombinase that acts by a concerted break-and-join mechanism. To analyse the role of individual resolvase subunits in DNA...

Neuregulin receptors, erbB3 and erbB4, are localized at neuromuscular synapses.

Zhu, X, Lai, C, Thomas, S, Burden, S J

Neuregulin (NRG) is concentrated at synaptic sites and stimulates expression of acetylcholine receptor (AChR) genes in muscle cells grown in cell culture. These results raise the possibility that NRG...

Targeted integration of adeno-associated virus (AAV) into human chromosome 19.

Samulski, R J, Zhu, X, Xiao, X, Brook, J D, Housman, D E, Epstein, N, ...

A key feature in adeno-associated virus (AAV) replication is efficient integration of the viral genome into host cell DNA to establish latency when helper virus is absent. The steps involved in this...

Functional characterization of two human sulphotransferase cDNAs that encode monoamine- and phenol-sulphating forms of phenol sulphotransferase: substrate kinetics, thermal-stability and inhibitor-sensitivity studies.

Veronese, M E, Burgess, W, Zhu, X, McManus, M E

The present paper describes the functional characterization of two human aryl sulphotransferase (HAST) cDNAs, HAST1 and HAST3, previously isolated by us from liver and brain, respectively [Zhu,...

Evidence of ectokinase-mediated phosphorylation of osteopontin and bone sialoprotein by osteoblasts during bone formation in vitro.

Zhu, X, Luo, C, Ferrier, J M, Sodek, J

Osteopontin (OPN) and bone sialoprotein (BSP) are phosphorylated glycoproteins that, together with osteonectin/secreted protein, acidic, rich in cysteine (SPARC) and osteocalcin, comprise the major...

Characterization and gene structure of a novel retinoblastoma-protein-associated protein similar to the transcription regulator TFII-I.

Yan, X, Zhao, X, Qian, M, Guo, N, Gong, X, Zhu, X

Retinoblastoma protein (Rb) is an important regulator of vertebrate cell cycle and development. It functions through a direct interaction with protein factors involved in cell cycle progression and...

Characterization of a calcium-regulation domain of the skeletal-muscle ryanodine receptor.

Hayek, S M, Zhu, X, Bhat, M B, Zhao, J, Takeshima, H, Valdivia, H H, ...

A negatively charged region of the N-terminal portion of the skeletal ryanodine receptor (RyR), located between residues 1872-1923, is involved in Ca (2+)-dependent regulation of the Ca(2+)-release...

The catabolic function of the alpha-aminoadipic acid pathway in plants is associated with unidirectional activity of lysine-oxoglutarate reductase, but not saccharopine dehydrogenase.

Zhu, X, Tang, G, Galili, G

Whereas plants and animals use the alpha-aminoadipic acid pathway to catabolize lysine, yeast and fungi use the very same pathway to synthesize lysine. These two groups of organisms also possess...

Direct observation of one-dimensional diffusion and transcription by Escherichia coli RNA polymerase.

Guthold, M, Zhu, X, Rivetti, C, Yang, G, Thomson, N H, Kasas, S, ...

The dynamics of nonspecific and specific Escherichia coli RNA polymerase (RNAP)-DNA complexes have been directly observed using scanning force microscopy operating in buffer. To this end, imaging...

A test of transmission/disequilibrium for quantitative traits in pedigree data, by multiple regression.

George, V, Tiwari, H K, Zhu, X, Elston, R C

The transmission/disequilibrium (TD) test (TDT), proposed, by Spielman et al., for binary traits is a powerful method for detection of linkage between a marker locus and a disease locus, in the...

AML1 is expressed in skeletal muscle and is regulated by innervation.

Zhu, X, Yeadon, J E, Burden, S J

Although most skeletal muscle genes are expressed at similar levels in electrically active, innervated muscle and in electrically inactive, denervated muscle, a small number of genes, including those...

Comparison of Physician- and Self-Collected Genital Specimens for Detection of Human Papillomavirus in Men

Hernandez, Brenda Y., McDuffie, K., Goodman, M. T., Wilkens, L. R., Thompson, P., Zhu, X., ...

There is currently no consensus regarding the most appropriate methods of sampling for the detection of genital human papillomavirus (HPV) in men. We employed a recently developed collection method...

Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes.

Vaziri, H, Schächter, F, Uchida, I, Wei, L, Zhu, X, Effros, R, ...

The telomere hypothesis of cellular aging proposes that loss of telomeric DNA (TTAGGG) from human chromosomes may ultimately cause cell-cycle exit during replicative senescence. Since lymphocytes...

Mutations in the C-terminal fragment of DnaK affecting peptide binding.

Burkholder, W F, Zhao, X, Zhu, X, Hendrickson, W A, Gragerov, A, Gottesman, M E

Escherichia coli DnaK acts as a molecular chaperone through its ATP-regulated binding and release of polypeptide substrates. Overexpressing a C-terminal fragment (CTF) of DnaK (Gly-384 to Lys-638)...

Cell cycle-dependent modulation of telomerase activity in tumor cells.

Zhu, X, Kumar, R, Mandal, M, Sharma, N, Sharma, H W, Dhingra, U, ...

Telomerase is a ribonucleoprotein complex that is thought to add telomeric repeats onto the ends of chromosomes during the replicative phase of the cell cycle. We tested this hypothesis by arresting...

Internal cleavage of the inhibitory 7B2 carboxyl-terminal peptide by PC2: a potential mechanism for its inactivation.

Zhu, X, Rouille, Y, Lamango, N S, Steiner, D F, Lindberg, I

The neuroendocrine protein 7B2 contains two domains, a 21-kDa protein required for prohormone convertase 2 (PC2) maturation and a carboxyl-terminal (CT) peptide that inhibits PC2 at nanomolar...

G protein subunits and the stimulation of phospholipase C by Gs-and Gi-coupled receptors: Lack of receptor selectivity of Galpha(16) and evidence for a synergic interaction between Gbeta gamma and the alpha subunit of a receptor activated G protein.

Zhu, X, Birnbaumer, L

Stimulatory guanine nucleotide binding protein (Gs)-coupled receptors activated by luteinizing hormone, vasopressin, and the catecholamine isoproterenol (luteinizing hormone receptor, type 2...

Cue recognition and cue elaboration in learning from examples.

Zhu, X, Lee, Y, Simon, H A, Zhu, D

This paper describes the processes used by students to learn from worked-out examples and by working through problems. Evidence is derived from protocols of students learning secondary school...

Dominant lethal mutations in the plasma membrane H(+)-ATPase gene of Saccharomyces cerevisiae.

Harris, S L, Na, S, Zhu, X, Seto-Young, D, Perlin, D S, Teem, J H, ...

The plasma membrane H(+)-ATPase of Saccharomyces cerevisiae is an essential protein that is required to establish cellular membrane potential and maintain a normal internal pH. An Asp-378 to Asn...

Efficacy of beta 1-adrenergic receptors is lower than that of beta 2-adrenergic receptors.

Levy, F O, Zhu, X, Kaumann, A J, Birnbaumer, L

We investigated the relative activity at which fully occupied human beta 1- and beta 2-adrenergic receptors (beta 1AR and beta 2AR) activate the stimulatory G protein (Gs)/adenylyl cyclase (AC)...

A myo-inositol pool utilized for phosphatidylinositol synthesis is depleted in sciatic nerve from rats with streptozotocin-induced diabetes.

Zhu, X, Eichberg, J

Peripheral nerve from experimentally diabetic rats exhibits lowered levels of myo-inositol (MI) and decreased incorporation of [3H]MI into phosphatidylinositol (PI). There are indications that...

Tyrosine 106 of CheY plays an important role in chemotaxis signal transduction in Escherichia coli.

Zhu, X, Amsler, C D, Volz, K, Matsumura, P

CheY is the response regulator in the signal transduction pathway of bacterial chemotaxis. Position 106 of CheY is occupied by a conserved aromatic residue (tyrosine or phenylalanine) in the response...

The ispB gene encoding octaprenyl diphosphate synthase is essential for growth of Escherichia coli.

Okada, K, Minehira, M, Zhu, X, Suzuki, K, Nakagawa, T, Matsuda, H, ...

The Escherichia coli ispB gene encoding octaprenyl diphosphate synthase is responsible for the synthesis of the side chain of isoprenoid quinones. We tried to construct an E. coli ispB-disrupted...

Cloning of the sdsA gene encoding solanesyl diphosphate synthase from Rhodobacter capsulatus and its functional expression in Escherichia coli and Saccharomyces cerevisiae.

Okada, K, Kamiya, Y, Zhu, X, Suzuki, K, Tanaka, K, Nakagawa, T, ...

Different organisms produce different species of isoprenoid quinones, each with its own distinctive length. These differences in length are commonly exploited in microbial classification. The side...

Cellular recombination pathways and viral terminal repeat hairpin structures are sufficient for adeno-associated virus integration in vivo and in vitro.

Yang, C C, Xiao, X, Zhu, X, Ansardi, D C, Epstein, N D, Frey, M R, ...

The human parvovirus adeno-associated virus (AAV) is unique in its ability to target viral integration to a specific site on chromosome 19 (ch-19). Recombinant AAV (rAAV) vectors retain the ability...

Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression.

Zhu, X, Mancini, M A, Chang, K H, Liu, C Y, Chen, C F, Shan, B, ...

A gene assigned to human chromosome 1q32-41 encodes a novel protein of 3,113 amino acids containing an internal tandem repeat of 177 amino acids. The protein, which we have named "mitosin," was...

Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase.

Zhu, X, Wen, Z, Xu, L Z, Darnell, J E

Gamma interferon (IFN-gamma) induces both tyrosine and serine phosphorylation of Stat1. Stat1 serine phosphorylation is required for maximal transcriptional activity of Stat1. In this report, we...

Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation.

Zhu, X, Assoian, R K

Adhesion to extracellular matrix mediates cell cycle progression in mid-late G1; this effect involves an integrin-dependent organization of the cytoskeleton and a consequent change in cell shape. In...

A simple and efficient method for site-directed mutagenesis with double-stranded plasmid DNA.

Lai, D, Zhu, X, Pestka, S

A general, simple and efficient method for preparing site-specific mutations in double-stranded plasmid DNA without the need for special plasmids, bacterial strains or reagents is described. Only one...

Studies on the intrinsic activity (efficacy) of human adrenergic receptors. Co-expression of beta 1 and beta 2 reveals a lower efficacy for the beta 1 receptor.

Birnbaumer, L, Levy, F O, Zhu, X, Kaumann, A J

Through co-expression of the human beta 1 and beta 2 adrenergic receptors in a single tester cell (the murine L fibroblast) and through assaying the effect of the beta 1 and beta 2 selective blockers...

AML1 is expressed in skeletal muscle and is regulated by innervation.

Zhu, X, Yeadon, J E, Burden, S J

Although most skeletal muscle genes are expressed at similar levels in electrically active, innervated muscle and in electrically inactive, denervated muscle, a small number of genes, including those...

Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F.

Shan, B, Zhu, X, Chen, P L, Durfee, T, Yang, Y, Sharp, D, ...

The retinoblastoma protein interacts with a number of cellular proteins to form complexes which are probably crucial for its normal physiological function. To identify these proteins, we isolated...

Mutations in the RB1 gene and their effects on transcription.

Dunn, J M, Phillips, R A, Zhu, X, Becker, A, Gallie, B L

Inactivation of both alleles of the RB1 gene during normal retinal development initiates the formation of a retinoblastoma (RB) tumor. To identify the mutations which inactivate RB1, 21 RB tumors...

Catalytic residues of gamma delta resolvase act in cis.

Boocock, M R, Zhu, X, Grindley, N D

The resolvase protein of the gamma delta transposon is a site-specific recombinase that acts by a concerted break-and-join mechanism. To analyse the role of individual resolvase subunits in DNA...

Neuregulin receptors, erbB3 and erbB4, are localized at neuromuscular synapses.

Zhu, X, Lai, C, Thomas, S, Burden, S J

Neuregulin (NRG) is concentrated at synaptic sites and stimulates expression of acetylcholine receptor (AChR) genes in muscle cells grown in cell culture. These results raise the possibility that NRG...

Targeted integration of adeno-associated virus (AAV) into human chromosome 19.

Samulski, R J, Zhu, X, Xiao, X, Brook, J D, Housman, D E, Epstein, N, ...

A key feature in adeno-associated virus (AAV) replication is efficient integration of the viral genome into host cell DNA to establish latency when helper virus is absent. The steps involved in this...

Functional characterization of two human sulphotransferase cDNAs that encode monoamine- and phenol-sulphating forms of phenol sulphotransferase: substrate kinetics, thermal-stability and inhibitor-sensitivity studies.

Veronese, M E, Burgess, W, Zhu, X, McManus, M E

The present paper describes the functional characterization of two human aryl sulphotransferase (HAST) cDNAs, HAST1 and HAST3, previously isolated by us from liver and brain, respectively [Zhu,...

Evidence of ectokinase-mediated phosphorylation of osteopontin and bone sialoprotein by osteoblasts during bone formation in vitro.

Zhu, X, Luo, C, Ferrier, J M, Sodek, J

Osteopontin (OPN) and bone sialoprotein (BSP) are phosphorylated glycoproteins that, together with osteonectin/secreted protein, acidic, rich in cysteine (SPARC) and osteocalcin, comprise the major...

Characterization and gene structure of a novel retinoblastoma-protein-associated protein similar to the transcription regulator TFII-I.

Yan, X, Zhao, X, Qian, M, Guo, N, Gong, X, Zhu, X

Retinoblastoma protein (Rb) is an important regulator of vertebrate cell cycle and development. It functions through a direct interaction with protein factors involved in cell cycle progression and...

Characterization of a calcium-regulation domain of the skeletal-muscle ryanodine receptor.

Hayek, S M, Zhu, X, Bhat, M B, Zhao, J, Takeshima, H, Valdivia, H H, ...

A negatively charged region of the N-terminal portion of the skeletal ryanodine receptor (RyR), located between residues 1872-1923, is involved in Ca (2+)-dependent regulation of the Ca(2+)-release...

The catabolic function of the alpha-aminoadipic acid pathway in plants is associated with unidirectional activity of lysine-oxoglutarate reductase, but not saccharopine dehydrogenase.

Zhu, X, Tang, G, Galili, G

Whereas plants and animals use the alpha-aminoadipic acid pathway to catabolize lysine, yeast and fungi use the very same pathway to synthesize lysine. These two groups of organisms also possess...

Direct observation of one-dimensional diffusion and transcription by Escherichia coli RNA polymerase.

Guthold, M, Zhu, X, Rivetti, C, Yang, G, Thomson, N H, Kasas, S, ...

The dynamics of nonspecific and specific Escherichia coli RNA polymerase (RNAP)-DNA complexes have been directly observed using scanning force microscopy operating in buffer. To this end, imaging...

A test of transmission/disequilibrium for quantitative traits in pedigree data, by multiple regression.

George, V, Tiwari, H K, Zhu, X, Elston, R C

The transmission/disequilibrium (TD) test (TDT), proposed, by Spielman et al., for binary traits is a powerful method for detection of linkage between a marker locus and a disease locus, in the...

Comparison of Physician- and Self-Collected Genital Specimens for Detection of Human Papillomavirus in Men

Hernandez, Brenda Y., McDuffie, K., Goodman, M. T., Wilkens, L. R., Thompson, P., Zhu, X., ...

There is currently no consensus regarding the most appropriate methods of sampling for the detection of genital human papillomavirus (HPV) in men. We employed a recently developed collection method...

Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes.

Vaziri, H, Schächter, F, Uchida, I, Wei, L, Zhu, X, Effros, R, ...

The telomere hypothesis of cellular aging proposes that loss of telomeric DNA (TTAGGG) from human chromosomes may ultimately cause cell-cycle exit during replicative senescence. Since lymphocytes...

Vaccination with recombinant vaccinia viruses protects mice against Mycobacterium tuberculosis infection.

Zhu, X, Venkataprasad, N, Ivanyi, J, Vordermeier, H M

A number of subunit-based vaccine candidates have recently begun to erode the exclusive position of Mycobacterium bovis bacillus Calmette-Guérin (BCG), which gives unpredictable and highly variable...

38 000 MW antigen-specific major histocompatibility complex class I restricted interferon-gamma-secreting CD8+ T cells in healthy contacts of tuberculosis.

Wilkinson, R J, Zhu, X, Wilkinson, K A, Lalvani, A, Ivanyi, J, Pasvol, G, ...

CD8+ T lymphocytes are required to protect mice against Mycobacterium tuberculosis, although in early infection the mechanism appears not to be via perforin or granzyme-mediated lysis of the infected...

Chloroquine inhibits macrophage tumour necrosis factor-alpha mRNA transcription.

Zhu, X, Ertel, W, Ayala, A, Morrison, M H, Perrin, M M, Chaudry, I H

Although chloroquine administration in vivo following haemorrhage in mice decreases tumour necrosis factor-alpha (TNF-alpha) release by macrophage (M phi), the mechanism remains unknown. To study...

Hepatocyte growth factor and its receptor (c-MET) in prostatic carcinoma.

Humphrey, P. A., Zhu, X., Zarnegar, R., Swanson, P. E., Ratliff, T. L., Vollmer, R. T., ...

Hepatocyte growth factor (scatter factor) and its receptor, the c-met proto-oncogene product (c-MET), have been implicated in embryogenesis, tissue reorganization, and tumor progression. Little is...

Bacterial expression of two human aryl sulfotransferases

Bidwell, LM, Gillam, EMJ, Gaedigk, A, Zhu, X, Grant, D, McManus, ME

The effect of replacing a single codon in the N-terminal of human aryl sulfotransferase (HAST) 1 and 3 with one that is more commonly found in E. coli genes was assessed. The pKK233-2 E. coli...

Involvement of protein tyrosine kinases in activation of human eosinophils by platelet-activating factor

Dent, G, Muñoz, N M, Zhu, X, Rühlmann, E, Magnussen, H, Leff, A R, ...

Activation of human eosinophils by platelet-activating factor (PAF) involves multiple signal transduction pathways. Among these, protein kinase C has been demonstrated both to mediate respiratory...