Xiao-Jun Xu

Correlational analysis for identifying genes whose regulation contributes to chronic neuropathic pain (2009)

Persson, Anna-Karin, Gebauer, Mathias, Jordan, Suzana, Metz-Weidmann, Christiane, Schulte, Anke M, Schneider, Hans-Christoph, ...

Abstract Background Nerve injury-triggered hyperexcitability in primary sensory neurons is considered a major source of chronic neuropathic pain. The hyperexcitability, in turn, is thought to be...

Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor

Johansson, Björn, Halldner, Linda, Dunwiddie, Thomas V., Masino, Susan A., Poelchen, Wolfgang, Giménez-Llort, Lydia, ...

Caffeine is believed to act by blocking adenosine A1 and A2A receptors (A1R, A2AR), indicating that some A1 receptors are tonically activated. We generated mice with a targeted disruption of the...

Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor

Johansson, Björn, Halldner, Linda, Dunwiddie, Thomas V., Masino, Susan A., Poelchen, Wolfgang, Giménez-Llort, Lydia, ...

Caffeine is believed to act by blocking adenosine A1 and A2A receptors (A1R, A2AR), indicating that some A1 receptors are tonically activated. We generated mice with a targeted disruption of the...

A nitric oxide (NO)-releasing derivative of gabapentin, NCX 8001, alleviates neuropathic pain-like behavior after spinal cord and peripheral nerve injury

Wu, Wei-Ping, Hao, Jing-Xia, Ongini, Ennio, Impagnatiello, Francesco, Presotto, Cristina, Wiesenfeld-Hallin, Zsuzsanna, ...

Nitric oxide (NO) participates, at least in part, to the establishment and maintenance of pain after nerve injury. Therefore, drugs that target the NO/cGMP signaling pathway are of interest for the...