Xiao-Ning Chen

Refined physical map of the human PAX2/HOX11/NFKB2cancer gene region at 10q24 and relocalization of the HPV6AI1 viral integration site to 14q13.3-q21.1 (2003)

Gough, Sheryl M, McDonald, Margaret, Chen, Xiao-Ning, Korenberg, Julie R, Neri, Antonino, Kahn, Tomas, ...

Abstract Background Chromosome band 10q24 is a gene-rich domain and host to a number of cancer, developmental, and neurological genes. Recurring translocations, deletions and mutations involving this...

Isolation and characterization of a candidate gene for progressive myoclonus epilepsy on 21q22.3 (1995)

Yamakawa, Kazuhiro, Mitchell, Steve, Hubert, René, Chen, Xiao-Ning, Colbern, Steve, Huo, Yong-Kang, ...

The Unverricht-Lundborg type of progressive myoclonus epilepsy (EPM1) and autoimmune polyglandular disease type I (APECED) have been mapped to human chromosome 21q22.3 by genetic linkage analysis...

Mouse Molecular Cytogenetic Resource: 157 BACs Link the Chromosomal and Genetic Maps

Korenberg, Julie R., Chen, Xiao-Ning, Devon, Keri L., Noya, David, Oster-Granite, Mary L., Birren, Bruce W.

We have established a collection of strong molecular cytogenetic markers that span the mouse autosomes and X chromosome at an average spacing of one per 19 Mb and identify 127 distinct band...

Human Genome Anatomy: BACs Integrating the Genetic and Cytogenetic Maps for Bridging Genome and Biomedicine

Korenberg, Julie R., Chen, Xiao-Ning, Sun, Zhiguang, Shi, Zheng-Yang, Ma, Shaowu, Vataru, Eddy, ...

Human genome sequencing is accelerating rapidly. Multiple genome maps link this sequence to problems in biology and clinical medicine. Because each map represents a different aspect of the structure,...

Up-Regulation of WNT-4 Signaling and Dosage-Sensitive Sex Reversal in Humans

Jordan, Brian K., Mohammed, Mansoor, Ching, Saunders T., Délot, Emmanuèle, Chen, Xiao-Ning, Dewing, Phoebe, ...

Wnt-4, a member of the Wnt family of locally acting secreted growth factors, is the first signaling molecule shown to influence the sex-determination cascade. In mice, a targeted deletion of Wnt-4...

Mouse Molecular Cytogenetic Resource: 157 BACs Link the Chromosomal and Genetic Maps

Korenberg, Julie R., Chen, Xiao-Ning, Devon, Keri L., Noya, David, Oster-Granite, Mary L., Birren, Bruce W.

We have established a collection of strong molecular cytogenetic markers that span the mouse autosomes and X chromosome at an average spacing of one per 19 Mb and identify 127 distinct band...

Human Genome Anatomy: BACs Integrating the Genetic and Cytogenetic Maps for Bridging Genome and Biomedicine

Korenberg, Julie R., Chen, Xiao-Ning, Sun, Zhiguang, Shi, Zheng-Yang, Ma, Shaowu, Vataru, Eddy, ...

Human genome sequencing is accelerating rapidly. Multiple genome maps link this sequence to problems in biology and clinical medicine. Because each map represents a different aspect of the structure,...

Up-Regulation of WNT-4 Signaling and Dosage-Sensitive Sex Reversal in Humans

Jordan, Brian K., Mohammed, Mansoor, Ching, Saunders T., Délot, Emmanuèle, Chen, Xiao-Ning, Dewing, Phoebe, ...

Wnt-4, a member of the Wnt family of locally acting secreted growth factors, is the first signaling molecule shown to influence the sex-determination cascade. In mice, a targeted deletion of Wnt-4...

The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies

Korbel, Jan O., Tirosh-Wagner, Tal, Urban, Alexander Eckehart, Chen, Xiao-Ning, Kasowski, Maya, Dai, Li, ...

Down syndrome (DS), or trisomy 21, is a common disorder associated with several complex clinical phenotypes. Although several hypotheses have been put forward, it is unclear as to whether particular...