Xiao-Song He

Appearance of Human Plasma Cells Following Differentiation of Human B Cells in NOD/SCID Mouse Spleen (2003)

Kentaro Kikuchi, Zhe-Xiong Lian, Xiao-Song He, Aftab A. Ansari, Miyuki Ishibashi, Hiroshi Miyakawa, ...

Relatively little is known for the differentiation and maturation process of human B cells to plasma cells. This is particularly important in reconstitution work involving transfer of autoantibodies....

Appearance of Human Plasma Cells Following Differentiation of Human B Cells in NOD/SCID Mouse Spleen (2003)

Kentaro Kikuchi, Zhe-Xiong Lian, Xiao-Song He, Aftab A. Ansari, Miyuki Ishibashi, Hiroshi Miyakawa, ...

Relatively little is known for the differentiation and maturation process of human B cells to plasma cells. This is particularly important in reconstitution work involving transfer of autoantibodies....

Quantitative analysis of hepatitis C virus-specific CD8+ T cells in peripheral blood and liver using peptide-MHC tetramers

He, Xiao-Song, Rehermann, Barbara, López-Labrador, F. Xavier, Boisvert, Judie, Cheung, Ramsey, Mumm, John, ...

It is believed that the hepatitis C virus (HCV)-specific CD8+ cytotoxic T lymphocytes (CTLs) play a role in the development of liver cell injury and in the clearance of the virus. To develop a direct...

Quantitative and functional analysis of PDC-E2–specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis

Kita, Hiroto, Matsumura, Shuji, He, Xiao-Song, Ansari, Aftab A., Lian, Zhe-Xiong, Van De Water, Judy, ...

While the pathologic mechanisms responsible for organ-specific tissue damage in primary biliary cirrhosis (PBC) remain an enigma, it has been suggested that the pathology is mediated by autoreactive...

T cell–dependent production of IFN-γ by NK cells in response to influenza A virus

He, Xiao-Song, Draghi, Monia, Mahmood, Kutubuddin, Holmes, Tyson H., Kemble, George W., Dekker, Cornelia L., ...

The role of human NK cells in viral infections is poorly understood. We used a cytokine flow-cytometry assay to simultaneously investigate the IFN-γ response of NK and T lymphocytes to influenza A...

Quantitative analysis of hepatitis C virus-specific CD8+ T cells in peripheral blood and liver using peptide-MHC tetramers

He, Xiao-Song, Rehermann, Barbara, López-Labrador, F. Xavier, Boisvert, Judie, Cheung, Ramsey, Mumm, John, ...

It is believed that the hepatitis C virus (HCV)-specific CD8+ cytotoxic T lymphocytes (CTLs) play a role in the development of liver cell injury and in the clearance of the virus. To develop a direct...

Quantitative and functional analysis of PDC-E2–specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis

Kita, Hiroto, Matsumura, Shuji, He, Xiao-Song, Ansari, Aftab A., Lian, Zhe-Xiong, Van De Water, Judy, ...

While the pathologic mechanisms responsible for organ-specific tissue damage in primary biliary cirrhosis (PBC) remain an enigma, it has been suggested that the pathology is mediated by autoreactive...

T cell–dependent production of IFN-γ by NK cells in response to influenza A virus

He, Xiao-Song, Draghi, Monia, Mahmood, Kutubuddin, Holmes, Tyson H., Kemble, George W., Dekker, Cornelia L., ...

The role of human NK cells in viral infections is poorly understood. We used a cytokine flow-cytometry assay to simultaneously investigate the IFN-γ response of NK and T lymphocytes to influenza A...

Cellular Immune Responses in Children and Adults Receiving Inactivated or Live Attenuated Influenza Vaccines▿

He, Xiao-Song, Holmes, Tyson H., Zhang, Caiqiu, Mahmood, Kutubuddin, Kemble, George W., Lewis, David B., ...

The patterns of cellular immune responses induced by live attenuated influenza vaccine (LAIV) versus those of the trivalent inactivated influenza vaccine (TIV) have not been studied extensively,...

Appearance of Human Plasma Cells Following Differentiation of Human B Cells in NOD/SCID Mouse Spleen

Kikuchi, Kentaro, Lian, Zhe-Xiong, He, Xiao-Song, Ansari, Aftab A., Ishibashi, Miyuki, Miyakawa, Hiroshi, ...

Relatively little is known for the differentiation and maturation process of human B cells to plasma cells. This is particularly important in reconstitution work involving transfer of autoantibodies....

Identification of HLA-A2–restricted CD8+ Cytotoxic T Cell Responses in Primary Biliary Cirrhosis: T Cell Activation Is Augmented by Immune Complexes Cross-Presented by Dendritic Cells

Kita, Hiroto, Lian, Zhe-Xiong, Van De Water, Judy, He, Xiao-Song, Matsumura, Shuji, Kaplan, Marshall, ...

Primary biliary cirrhosis (PBC) is characterized by an intense biliary inflammatory CD4+ and CD8+ T cell response. Very limited information on autoantigen-specific cytotoxic T lymphocyte (CTL)...

Appearance of Human Plasma Cells Following Differentiation of Human B Cells in NOD/SCID Mouse Spleen

Kikuchi, Kentaro, Lian, Zhe-Xiong, He, Xiao-Song, Ansari, Aftab A., Ishibashi, Miyuki, Miyakawa, Hiroshi, ...

Relatively little is known for the differentiation and maturation process of human B cells to plasma cells. This is particularly important in reconstitution work involving transfer of autoantibodies....

Influence of Prior Influenza Vaccination on Antibody and B-Cell Responses

Sasaki, Sanae, He, Xiao-Song, Holmes, Tyson H., Dekker, Cornelia L., Kemble, George W., Arvin, Ann. M., ...

Currently two vaccines, trivalent inactivated influenza vaccine (TIV) and live attenuated influenza vaccine (LAIV), are licensed in the USA. Despite previous studies on immune responses induced by...

Qualitative and Quantitative Characteristics of Rotavirus-Specific CD8 T Cells Vary Depending on the Route of Infection▿

Jiang, Janina Q., He, Xiao-Song, Feng, Ningguo, Greenberg, Harry B.

CD8 T-cell response provides an important defense against rotavirus, which infects a variety of systemic locations in addition to the gut. Here we investigated the distribution, phenotype, and...