Xiaoming Liu

Automatic Face Recognition from Skeletal Remains (2009)

Peter Tu, Rebecca Book, Xiaoming Liu, Nils Krahnstoever

The ability to determine the identity of a skull found at a crime scene is of critical importance to the law enforcement community. Traditional clay-based methods attempt to reconstruct the face so...

Inferring Population Mutation Rate and Sequencing Error Rate Using the SNP Frequency Spectrum in a Sample of DNA Sequences (2009)

Liu, Xiaoming, Maxwell, Taylor J., Boerwinkle, Eric, Fu, Yun-Xin

One challenge of analyzing samples of DNA sequences is to account for the nonnegligible polymorphisms produced by error when the sequencing error rate is high or the sample size is large....

Quiet, Do Not Disturb: Prying Open the Door to Examine Our Worlds of Testing and Assessment (2008)

Amma Akrofi, Carole Janisch, Mellinee Lesley, Robin Griffith, Xiaoming Liu

Teacher educators recount their personal experiences related to testing and assessment. Through the examination of these experiences stemming from collegial conversations, the individuals have come...

General Terms Design (2008)

Xiaoming Liu, Johan Bollen, Michael L. Nelson

Visualization eases insight into complex systems such as coauthorship networks. We present an initial deployment of an author navigator application for convenient visual examination of JCDL and LANL...

doi:10.1093/comjnl/bxh114 aDORe: A Modular, Standards-Based Digital Object Repository (2008)

Jeroen Bekaert, Xiaoming Liu, Luda Balakireva, Thorsten Schw

This paper describes the aDORe repository architecture designed and implemented for ingesting,

Draft of Submission to Oxford University Press Computer Journal aDORe: a modular, standards-based Digital Object Repository (2008)

Jeroen Bekaert, Xiaoming Liu, Luda Balakireva, Thorsten Schw

This paper describes the aDORe repository architecture, designed and implemented for ingesting, storing, and accessing a vast collection of Digital Objects at the Research Library of the Los Alamos...

in press) mod_oai: An Apache Module for Metadata Harvesting (2008)

Michael L. Nelson, Xiaoming Liu, Terry L. Harrison, Nathan Mcfarland

Abstract. We describe mod_oai, an Apache 2.0 module that implements the Open Archives Initiative Protocol for Metadata Harvesting (OAI-PMH). The OAI-PMH is the de facto standard for metadata exchange...

Online Modeling and Tracking of Pose-Varying Faces in Video (2008)

Xiaoming Liu

Human face recognition is an interesting and popular topic in the vision community. The most important part of a face recognition system is to handle all kinds of variations through modeling. There...

10.1117/2.1200706.0712 Surveillance video analytics for large camera networks (2008)

Peter Tu, Fred Wheeler, Nils Krahnstoever, Thomas Sebastian, Jens Rittscher, Xiaoming Liu, ...

Intelligent video research focuses on automatic camera calibration and person detection, tracking, and reacquisition. Extensive networks of surveillance cameras are increasingly deployed in public...

Gradient Feature Selection for Online Boosting (2008)

Xiaoming Liu, Ting Yu

Boosting has been widely applied in computer vision, especially after Viola and Jones’s seminal work [23]. The marriage of rectangular features and integral-imageenabled fast computation makes...

Algorithms to estimate the lower bounds of recombination with or without recurrent mutations (2008)

Liu, Xiaoming, Fu, Yun-Xin

Abstract Background An important method to quantify the effects of recombination on populations is to estimate the minimum number of recombination events, R min , in the history of a DNA sample....

© 2004 INFORMS (2008)

Liming Liu, Xiaoming Liu, David D. Yao

informs ® doi 10.1287/mnsc.1030.0196

DEAN DATE (2008)

Xiaoming Liu

Researchers have been working on human face recognition for decades. Face recognition is hard due to different types of variations in face images, such as pose, illumination and expression, among...

Tight Upper Bounds for Cell Loss Probabilities in ATM Multiplexers and Required Bandwidth Estimation (2007)

Xiaoming Liu, Brahim Bensaou, Liming Liu

Estimating the cell loss probability in an ATM multiplexer is a key issue in network management and traffic control such as call admission control and bandwidth allocation. In this paper, we derive a...

Synchronized OAI Caches (2007)

Xiaoming Liu, Kurt Maly, Mohammad Zubair, Rong Tang, Imran Padshah, George Roncaglia, ...

Laboratory and Old Dominion University to allow for the integration of technical reports. This is accomplished using the Open Archives Initiative Protocol for Metadata Harvesting (OAI-PMH) and having...

Clip (2007)

Xiaoming Liu, Yueting Zhuang, Yunhe Pan, P. R. China

The similarity measure between video clips is a key issue in video retrieval. In the developing of our video retrieval system, we propose a new video similarity model. In contrast to existing...

Arc−An OAI Service Provider for Cross−Archive Searching (2007)

Xiaoming Liu, Kurt Maly, Mohammad Zubair, Michael L. Nelson

The usefulness of the many on−line journals and scientific digital libraries that exist today is limited by the lack of a service that can federate them through a unified interface. The Open...

Improved face model fitting on video sequences (2007)

Xiaoming Liu, Frederick W. Wheeler, Peter H. Tu

Active Appearance Models (AAMs) represent the shape and appearance of an object via two low-dimensional subspaces, one for shape and one for appearance. AAMs for facial images are currently receiving...

What are customers looking at (2007)

Xiaoming Liu, Nils Krahnstoever, Ting Yu, Peter Tu

Computer vision approaches for retail applications can provide value far beyond the common domain of loss prevention. Gaining insight into the movement and behaviors of shoppers is of high interest...

Multi-frame image restoration for face recognition (2007)

Frederick W. Wheeler, Xiaoming Liu, Peter H. Tu, Ralph T. Hoctor

Face recognition at a distance is a challenging and important law-enforcement surveillance problem, with low image resolution and blur contributing to the difficulties. We present a method for...

Generic face alignment using boosted appearance model (2007)

Xiaoming Liu

This paper proposes a discriminative framework for efficiently aligning images. Although conventional Active Appearance Models (AAM)-based approaches have achieved some success, they suffer from the...

Pathways: Augmenting interoperability across scholarly repositories (2006)

Warner, Simeon, Bekaert, Jeroen, Lagoze, Carl, Liu, Xiaoming, Payette, Sandy, Van De Sompel, Herbert

In the emerging eScience environment, repositories of papers, datasets, software, etc., should be the foundation of a global and natively-digital scholarly communications system. The current...

Numerical Simulations of Gulf Stream Meanders and Eddies and Their Effects on the Cross-Shelf Transport off the Carolina Coast (2006)

Liu, Xiaoming

Gulf Stream meanders and eddies off the Carolina coast are studied using an ocean numerical model. Numerical simulation results show that the isobathic curvature in the vicinity of the Charleston...

Face model fitting on low resolution images (2006)

Xiaoming Liu, Peter H. Tu, Frederick W. Wheeler

Active Appearance Models (AAMs) represent the shape and appearance of an object via two low-dimensional subspaces, one for shape and one for appearance. AAMs for facial images are currently receiving...

Representing Digital Assets for Long-Term Preservation using MPEG-21 DID (2005)

Bekaert, Jeroen, Liu, Xiaoming, Van De Sompel, Herbert

Various efforts aimed at representing digital assets have emerged from several communities over the last years, including the Metadata Encoding and Transmission Standard (METS), the IMS Content...

mod_oai: An Apache Module for Metadata Harvesting (2005)

Nelson, Michael L., Van De Sompel, Herbert, Liu, Xiaoming, Harrison, Terry L., McFarland, Nathan

We describe mod_oai, an Apache 2.0 module that implements the Open Archives Initiative Protocol for Metadata Harvesting (OAI-PMH). OAIPMH is the de facto standard for metadata exchange in digital...

File-based storage of Digital Objects and constituent datastreams: XMLtapes and Internet Archive ARC files (2005)

Liu, Xiaoming, Balakireva, Lyudmila, Hochstenbach, Patrick, Van De Sompel, Herbert

This paper introduces the write-once/read-many XMLtape/ARC storage approach for Digital Objects and their constituent datastreams. The approach combines two interconnected file-based storage...

Co-Authorship Networks in the Digital Library Research Community (2005)

Liu, Xiaoming, Bollen, Johan, Nelson, Michael L., Van De Sompel, Herbert

The field of digital libraries (DLs) coalesced in 1994: the first digital library conferences were held that year, awareness of the World Wide Web was accelerating, and the National Science...

aDORe: a modular, standards-based Digital Object Repository (2005)

Van De Sompel, Herbert, Bekaert, Jeroen, Liu, Xiaoming, Balakireva, Luda, Schwander, Thorsten

This paper describes the aDORe repository architecture, designed and implemented for ingesting, storing, and accessing a vast collection of Digital Objects at the Research Library of the Los Alamos...

Harvesting Resources with OAI-PMH (2005)

De Sompel, Xiaoming Liu, Michael L. Nelson, Carl Lagoze, Simeon Warner, Terry Harrison, ...

The problem is not that the WWW doesn’t work; it clearly does. The problem is that our expectations have been lowered. more on DL/WWW, from the NSF Post-DL Workshop:

Pose-Robust Face Recognition Using Geometry Assisted Probabilistic Modeling (2005)

Xiaoming Liu

Researchers have been working on human face recognition for decades. Face recognition is hard due to different types of variations in face images, such as pose, illumination and expression, among...

aDORe: A Modular, Standards-Based Digital Object Repository (2005)

Van De Sompel, Herbert, Bekaert, Jeroen, Liu, Xiaoming, Balakireva, Luda, Schwander, Thorsten

This paper describes the aDORe repository architecture designed and implemented for ingesting, storing, and accessing a vast collection of Digital Objects at the Research Library of the Los Alamos...

aDORe: A Modular, Standards-Based Digital Object Repository (2005)

Van De Sompel, Herbert, Bekaert, Jeroen, Liu, Xiaoming, Balakireva, Luda, Schwander, Thorsten

This paper describes the aDORe repository architecture designed and implemented for ingesting, storing, and accessing a vast collection of Digital Objects at the Research Library of the Los Alamos...

The multi-faceted use of the OAI-PMH in the LANL Repository (2004)

Jerez, Henry, Liu, Xiaoming, Hochstenbach, Patrick, Van De Sompel, Herbert

This paper focuses on the multifaceted use of the OAI-PMH in a repository architecture designed to store digital assets at the Research Library of the Los Alamos National Laboratory (LANL), and to...

The multi-faceted use of the OAI-PMH in the LANL repository (2004)

Henry N. Jerez, Xiaoming Liu, Patrick Hochstenbach

This paper focuses on the multifaceted use of the OAI-PMH in a repository architecture designed to store digital assets at the Research Library of the Los Alamos National Laboratory (LANL), and to...

Age-of-onset of hypertension vs. a single measurement of systolic blood pressure in a combined linkage and segregation analysis (2003)

Daw, E Warwick, Liu, Xiaoming, Wu, Chih-Chieh

Abstract Background Often, multiple measures of a trait are available in a genetic linkage analysis. We compare Monte Carlo Markov chain analysis of two very different measures of hypertension in the...

Developmental Capacity of Ferret Embryos by Nuclear Transfer Using G0/G1-Phase Fetal Fibroblasts1 (2003)

Ziyi Li, Maryam Rezaei Sabet, Qi Zhou, Xiaoming Liu, Wei Ding, Yulong Zhang, ...

With the ultimate goal of establishing experimental protocols necessary for cloning ferrets, the present study has established parameters for the reconstruction of ferret embryos by nuclear transfer...

Study of high speed electrolytic in-process dressing (2003)

Liu, Xiaoming

This research emphasizes on the development of an effective technique for electrolytic in-process dressing (ELID) of super-abrasive wheels for high-speed grinding. ELID is a precise and consistent...

Study of high speed electrolytic in-process dressing / (2003)

Liu, Xiaoming.

Thesis (Ph. D.)--Stevens Institute of Technology, 2003.

Geometry-assisted statistical modeling for face mosaicing (2003)

Xiaoming Liu, Tsuhan Chen

The modeling of facial appearance has many applications. This paper proposes an approach to generating a statistical face model based on video mosaicing. Unlike traditional video mosaicing, we use...

Repository synchronization in the OAI framework (2003)

Xiaoming Liu

The Open Archives Initiative Protocol for Metadata Harvesting (OAI-PMH) began as an alternative to distributed searching of scholarly eprint repositories. The model embraced by the OAI-PMH is that of...

Video-based face recognition using adaptive hidden markov models (2003)

Xiaoming Liu, Tsuhan Chen

While traditional face recognition is typically based on still images, face recognition from video sequences has become popular recently. In this paper, we propose to use adaptive Hidden Markov...

Geometry-assisted statistical modeling for face mosaicing (2003)

Xiaoming Liu, Tsuhan Chen

The modeling of facial appearance has many applications. This paper proposes an approach to generating a statistical face model based on video mosaicing. Unlike traditional video mosaicing, we use...

Face authentication for multiple subjects using eigenflow (2003)

Xiaoming Liu, Tsuhan Chen

In this paper, we present a novel scheme for face authentication. To deal with variations, such as facial expressions and registration errors, with which traditional intensity-based methods do not...

Eigenspace updating for non-stationary process and its application to face recognition (2003)

Xiaoming Liu, Tsuhan Chen, Susan M. Thornton

In this paper, we introduce a novel approach to modeling non-stationary random processes. Given a set of training samples sequentially, we can iteratively update an eigenspace to manifest the current...

A Scalable Architecture for Harvest-Based Digital Libraries - The ODU/Southampton Experiments (2002)

Liu, Xiaoming, Brody, Tim, Harnad, Stevan, Carr, Les, Maly, Kurt, Zubair, Mohammad, ...

This paper discusses the requirements of current and emerging applications based on the Open Archives Initiative (OAI) and emphasizes the need for a common infrastructure to support them. Inspired by...

A Scalable Architecture for Harvest-Based Digital Libraries - The ODU/Southampton Experiments (2002)

Liu, Xiaoming, Brody, Tim, Harnad, Stevan, Carr, Les, Maly, Kurt, Zubair, Mohammad, ...

This paper discusses the requirements of current and emerging applications based on the Open Archives Initiative (OAI) and emphasizes the need for a common infrastructure to support them. Inspired by...

A Scalable Architecture for Harvest-Based Digital Libraries - The ODU/Southampton Experiments (2002)

Liu, Xiaoming, Brody, Tim, Harnad, Stevan, Carr, Les, Maly, Kurt, Zubair, Mohammad, ...

This paper discusses the requirements of current and emerging applications based on the Open Archives Initiative (OAI) and emphasizes the need for a common infrastructure to support them. Inspired by...

A Scalable Architecture for Harvest-Based Digital Libraries - The ODU/Southampton Experiments (2002)

Liu, Xiaoming, Brody, Tim, Harnad, Stevan, Carr, Les, Maly, Kurt, Zubair, Mohammad, ...

This paper discusses the requirements of current and emerging applications based on the Open Archives Initiative (OAI) and emphasizes the need for a common infrastructure to support them. Inspired by...

DP9 - an OAI gateway service for Web crawlers (2002)

Xiaoming Liu, Kurt Maly, Mohammad Zubair

Many libraries and databases are closed to general-purpose Web crawlers, and they expose their content only through their own search engines. At the same time many researchers attempt to locate...

On modeling variations for face authentication (2002)

Xiaoming Liu, Tsuhan Chen

In this paper, we present a scheme for face authentication by using applying principal component analysis (PCA) to model variations. To deal with variations, such as facial expressions and...

The Open Archives Initiative Protocol for Metadata Harvesting (OAI-PMH) (2002)

Xiaoming Liu, Tim Brody, Stevan Harnad, Les Carr, Kurt Maly, Mohammad Zubair, ...

This paper discusses the requirements of current and emerging applications based on the Open Archives Initiative (OAI) and emphasizes the need for a common infrastructure to support them. Inspired by...

Proving hybrid ¡ protocols correct (2001)

Mark Bickford, Christoph Kreitz, Robbert Van Renesse, Xiaoming Liu

Abstract. We describe a generic switching protocol for the construction of hybrid protocols and prove it correct with the Nuprl proof development system. For this purpose we introduce the concept of...

Arc: an OAI service provider for cross-archive searching (2001)

Xiaoming Liu, Kurt Maly, Mohammad Zubair, Michael L. Nelson

The usefulness of the many on-line journals and scientific digital libraries that exist today is limited by the lack of a service that can federate them through a unified interface. The Open Archive...

Protocol switching: Exploiting meta-properties (2001)

Xiaoming Liu, Robbert Van Renesse, Mark Bickford, Christoph Kreitz, Robert Constable

As we see a growing variety of network and application behaviors, it becomes more important that protocols adapt to their surroundings. Building adaptive protocols is complicated, and therefore we...

Advanced Multimedia Processing Lab (2001)

Xiaoming Liu, Tsuhan Chen

In this paper, we present a novel scheme for face authentication. To deal with variations, such as facial expressions and registration errors, with which traditional intensity-based methods do not...

Protocol switching: Exploiting meta-properties (2001)

Xiaoming Liu, Robbert Van Renesse, Mark Bickfordchristoph Kreitz, Robert Constable

Abstract As we see a growing variety of network and applica-tion behaviors, it becomes more important that protocols adapt to their surroundings. Building adaptive protocolsis complicated, and...

Proving hybrid ¡ protocols correct (2001)

Mark Bickford, Christoph Kreitz, Robbert Van Renesse, Xiaoming Liu

Abstract. We describe a generic switching protocol for the construction of hybrid protocols and prove it correct with the Nuprl proof development system. For this purpose we introduce the concept of...

Protocol switching: Exploiting meta-properties (2001)

Xiaoming Liu, Robbert Van Renesse, Mark Bickford, Christoph Kreitz, Robert Constable

As we see a growing variety of network and application behaviors, it becomes more important that protocols adapt to their surroundings. Building adaptive protocols is complicated, and therefore we...

The UPS Prototype. An Experimental End-User Service across E-Print Archives (2000)

Sompel, Herbert Van De, Krichel, Thomas, Nelson, Michael L., Hochstenbach, Patrick, Lyapunov, Victor M., Maly, Kurt, ...

A meeting was held in Santa Fe, New Mexico, October 21-22, 1999, to generate discussion and consensus about interoperability of publicly available scholarly information archives. The invitees...

The UPS Prototype project: exploring the obstacles in creating a cross-print archive end-user service", D-Lib Magazine (2000)

Michael L. Nelson, Victor M. Lyapunov, Mohammad Zubair, Xiaoming Liu, Thomas Krichel, ...

The Universal Preprint Service (UPS) Prototype was developed in preparation of the first meeting of the UPS initiative - later renamed the Open Archives initiative - held in Santa Fe, New Mexico...

Tight upper bounds for cell loss probabilities and required bandwidth estimation in ATM multipl[e]xers (1999)

Liu, Xiaoming, Bensaou, Brahim, Tsang, Danny H. K., Liu, Liming

Estimating the cell loss probability in an ATM multiplexer is a key issue in network management and traffic control tasks such as call admission control and bandwidth allocation. In this paper, we...

Video based human animation technique (1999)

Xiaoming Liu, Yueting Zhuang, Yunhe Pan

Human animation is a challenging domain in computer animation. To aim at many shortcomings in conventional techniques, this paper proposes a new video based human animation technique. Given a clip of...

Building Reliable, High-Performance Communication Systems from Components (1999)

Xiaoming Liu, Christoph Kreitz, Robbert Van Renesse, Jason Hickey

Although building systems from components has attractions, this approach also has problems. Can we be sure that a certain configuration of components is correct? Can it perform as well as a...

Building Reliable, High-Performance Communication Systems From Components (1999)

Xiaoming Liu, Christoph Kreitz, Robbert Van Renesse, Jason Hickey, Mark Hayden, Kenneth Birman, ...

Although building systems from components has attractions, this approach also has problems. Can we be sure that a certain configuration of components is correct? Can it perform as well as a...

Structured Course Objects in a Digital Library (1999)

Kurt Maly, K. Maly, Xiaoming Liu, Mohammad Zubair, X. Liu, Michael Nelson, ...

We are developing an Undergraduate Digital Library Framework (UDLF) that will support creation/archiving of courses and reuse of existing course material to evolve courses. UDLF supports the...

Nuclear Retinoid Acid Receptor Beta in Bronchial Epithelium of Smokers Before and During Chemoprevention (1999)

Xu, Xiao-Chun, Lee, Jin S., Lee, J. Jack, Morice, Rodolfo C., Liu, Xiaoming, Lippman, Scott M., ...

BACKGROUND: Retinoids can reverse neoplastic lesions and prevent second primary tumors in the aerodigestive tract. These effects are thought to be mediated by nuclear retinoic acid receptors (RARs)...

Building reliable, high-performance communication systems from components. Operating Systems Review 34(5):80–92 (1999)

Xiaoming Liu, Christoph Kreitz, Robbert Van Renesse, Jason Hickey

Although building systems from components has attractions, this approach also has problems. Can we be sure that a certain configuration of components is correct? Can it perform as well as a...

Building reliable, high-performance communication systems from components (1999)

Xiaoming Liu, Christoph Kreitz, Robbert Van Renesse, Jason Hickey, Mark Hayden, Kenneth Birman, ...

Although building systems from components has attractions, this approach also has problems. Can we be sure that a certain configuration of components is correct? Can it perform as well as a...

Performance analysis and optimization of supply networks /--by Xiaoming Liu. (1998)

Liu, Xiaoming.

Thesis (Ph. D.)--Hong Kong University of Science and Technology, 1998.

Monte Carlo Analysis of Nonequilibrium Ionized Flows. (1997)

Boyd, Iain D., Liu, Xiaoming, Balakrishnan, Jitendra

This final report summarizes the research carried out by our research group concerned with the development of a numerical approach for simulating the flows through and expanding from low-power...

Tight upper bounds for cell loss probabilities in ATM multiplexers and required bandwidth estimation (1997)

Liu, Xiaoming, Bensaou, Brahim, Tsang, Danny H. K., Liu, Liming

Estimating the cell loss probability in an ATM multiplexer is a key issue in network management and traffic control such as call admission control and bandwidth allocation. In this paper, we derive a...

Analysis and Optimization of a Multi-Stage Inventory-Queue System (1992)

Liming Liu, Xiaoming Liu, David D. Yao

An important issue in supply chain and/or manufacturing system management is controlling inventory costs at different locations in the system while satisfying a final customer service level...

IκBα and IκBβ possess injury context-specific functions that uniquely influence hepatic NF-κB induction and inflammation

Fan, Chenguang, Li, Qiang, Zhang, Yulong, Liu, Xiaoming, Luo, Meihui, Abbott, Duane, ...

IκB proteins play an important role in regulating NF-κB induction following a diverse range of environmental injuries. Studies evaluating IκBβ knock-in mice (AKBI), in which the IκBα gene is...

Targeted Correction of Single-Base-Pair Mutations with Adeno-Associated Virus Vectors under Nonselective Conditions

Liu, Xiaoming, Yan, Ziying, Luo, Meihui, Zak, Roman, Li, Ziyi, Driskell, Ryan R., ...

Recombinant adeno-associated virus (rAAV) vectors possess the unique ability to introduce genetic alterations at sites of homology in genomic DNA through a mechanism thought to predominantly involve...

IκBα and IκBβ possess injury context-specific functions that uniquely influence hepatic NF-κB induction and inflammation

Fan, Chenguang, Li, Qiang, Zhang, Yulong, Liu, Xiaoming, Luo, Meihui, Abbott, Duane, ...

IκB proteins play an important role in regulating NF-κB induction following a diverse range of environmental injuries. Studies evaluating IκBβ knock-in mice (AKBI), in which the IκBα gene is...

Targeted Correction of Single-Base-Pair Mutations with Adeno-Associated Virus Vectors under Nonselective Conditions

Liu, Xiaoming, Yan, Ziying, Luo, Meihui, Zak, Roman, Li, Ziyi, Driskell, Ryan R., ...

Recombinant adeno-associated virus (rAAV) vectors possess the unique ability to introduce genetic alterations at sites of homology in genomic DNA through a mechanism thought to predominantly involve...

Evidence for Recombination in Mycobacterium tuberculosis▿ †

Liu, Xiaoming, Gutacker, Michaela M., Musser, James M., Fu, Yun-Xin

Due to its mostly isolated living environment, Mycobacterium tuberculosis is generally believed to be highly clonal, and thus recombination between different strains must be rare and is not critical...

Test of Genetical Isochronism for Longitudinal Samples of DNA Sequences

Liu, Xiaoming, Fu, Yun-Xin

Longitudinal samples of DNA sequences, the DNA sequences sampled from the same population at different time points, have increasingly been used to study the evolutionary process of fast-evolving...

Bioelectric Properties of Chloride Channels in Human, Pig, Ferret, and Mouse Airway Epithelia

Liu, Xiaoming, Luo, Meihui, Zhang, Liang, Ding, Wei, Yan, Ziying, Engelhardt, John F.

The development of effective therapies for cystic fibrosis (CF) requires animal models that can appropriately reproduce the human disease phenotype. CF mouse models have demonstrated cAMP-inducible,...

PITX2 and β-Catenin Interactions Regulate Lef-1 Isoform Expression▿

Amen, Melanie, Liu, Xiaoming, Vadlamudi, Usha, Elizondo, Gabriela, Diamond, Evan, Engelhardt, John F., ...

Lef-1 and PITX2 function in the Wnt signaling pathway by recruiting and interacting with β-catenin to activate target genes. Chromatin immunoprecipitation (ChIP) assays identified the Lef-1 promoter...

Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin Agene

Jamaluddin, Md S., Chen, Irene, Yang, Fan, Jiang, Xiaohua, Jan, Michael, Liu, Xiaoming, ...

We reported previously that homocysteine (Hcy) inhibits endothelial cell (EC) growth by transcriptional inhibition of the cyclin A gene via a hypomethylation-related mechanism. In this study, we...

Cost-effective inventory control in a value-added manufacturing system

Liu, Xiaoming, Lian, Zhaotong

This paper considers the cost-effective inventory control of work-in-process (WIP) and finished products in a two-stage distributed manufacturing system. The first stage produces a common WIP, and...

Species-Specific Differences in Mouse and Human Airway Epithelial Biology of Recombinant Adeno-Associated Virus Transduction

Liu, Xiaoming, Yan, Ziying, Luo, Meihui, Engelhardt, John F.

Differences in airway epithelial biology between mice and humans have presented challenges to evaluating gene therapies for cystic fibrosis (CF) using murine models. In this context, recombinant...

The Glandular Stem/Progenitor Cell Niche in Airway Development and Repair

Liu, Xiaoming, Engelhardt, John F.

Airway submucosal glands (SMGs) are major secretory structures that lie beneath the epithelium of the cartilaginous airway. These glands are believed to play important roles in normal lung function...

A perishable inventory model with Markovian renewal demands

Lian, Zhaotong, Liu, Xiaoming, Zhao, Ning

In the inventory model, people usually assume that the inter-demand time is independently identical distributed which may not be true in reality. Here we study an (s,S) continuous review model for...