Xiaoping Liang

Design of immunogens that present the crown of the HIV-1 V3 loop in a conformation competent to generate 447-52D-like antibodies (2006)

Chakraborty, Kausik, Durani, Venuka, Roshan Miranda, Edward, Citron, Michael, Liang, Xiaoping, Schleif, William, ...

gp120 is a subunit of the envelope glycoprotein of HIV-1. The third variable loop region of gp120 (V3 loop) contains multiple immunodominant epitopes and is also functionally important for deciding...

Design of immunogens that present the crown of the HIV-1 V3 loop in a conformation competent to generate 447-52D-like antibodies (2006)

Chakraborty, Kausik, Durani, Venuka, Roshan Miranda, Edward, Citron, Michael, Liang, Xiaoping, Schleif, William, ...

gp120 is a subunit of the envelope glycoprotein of HIV-1. The third variable loop region of gp120 (V3 loop) contains multiple immunodominant epitopes and is also functionally important for deciding...

Characterization of gp120 and its Single-Chain Derivatives, $gp120-CD4_D_1_2$ and gp120-M9: Implications for Targeting the $CD4_i$ Epitope in Human Immunodeficiency Virus Vaccine Design (2005)

Varadarajan, Raghavan, Sharma, Deepak, Chakraborty, Kausik, Patel, Mayuri, Citron, Michael, Sinha, Prem, ...

Single-chain derivatives of JRFL gp120 linked to the first two domains of human CD4 $(gp120-CD4_D_1_2)$ or to the CD4 miniprotein analog CD4M9 (gp120-M9), have been constructed. Biacore studies...

Characterization of gp120 and its Single-Chain Derivatives, $gp120-CD4_D_1_2$ and gp120-M9: Implications for Targeting the $CD4_i$ Epitope in Human Immunodeficiency Virus Vaccine Design (2005)

Varadarajan, Raghavan, Sharma, Deepak, Chakraborty, Kausik, Patel, Mayuri, Citron, Michael, Sinha, Prem, ...

Single-chain derivatives of JRFL gp120 linked to the first two domains of human CD4 $(gp120-CD4_D_1_2)$ or to the CD4 miniprotein analog CD4M9 (gp120-M9), have been constructed. Biacore studies...

Mamu-A∗01 Allele-Mediated Attenuation of Disease Progression in Simian-Human Immunodeficiency Virus Infection

Zhang, Zhi-Qiang, Fu, Tong-Ming, Casimiro, Danilo R., Davies, Mary-Ellen, Liang, Xiaoping, Schleif, William A., ...

Expression of several major histocompatibility complex (MHC) class I alleles is associated with a protective effect against disease progression in both human immunodeficiency virus type 1 and simian...

Characterization of gp120 and Its Single-Chain Derivatives, gp120-CD4D12 and gp120-M9: Implications for Targeting the CD4i Epitope in Human Immunodeficiency Virus Vaccine Design

Varadarajan, Raghavan, Sharma, Deepak, Chakraborty, Kausik, Patel, Mayuri, Citron, Michael, Sinha, Prem, ...

Single-chain derivatives of JRFL gp120 linked to the first two domains of human CD4 (gp120-CD4D12) or to the CD4 miniprotein analog CD4M9 (gp120-M9), have been constructed. Biacore studies revealed...

Universal Influenza B Vaccine Based on the Maturational Cleavage Site of the Hemagglutinin Precursor

Bianchi, Elisabetta, Liang, Xiaoping, Ingallinella, Paolo, Finotto, Marco, Chastain, Michael A., Fan, Jiang, ...

Conventional influenza vaccines can prevent infection, but their efficacy depends on the degree of antigenic “match” between the strains used for vaccine preparation and those circulating in the...

Vectored Gag and Env but Not Tat Show Efficacy against Simian-Human Immunodeficiency Virus 89.6P Challenge in Mamu-A*01-Negative Rhesus Monkeys

Liang, Xiaoping, Casimiro, Danilo R., Schleif, William A., Wang, Fubao, Davies, Mary-Ellen, Zhang, Zhi-Qiang, ...

Simian-human immunodeficiency virus (SHIV) challenge studies in rhesus macaques were conducted to evaluate the efficacy of adenovirus-based vaccines in the context of different major...

Attenuation of Simian Immunodeficiency Virus SIVmac239 Infection by Prophylactic Immunization with DNA and Recombinant Adenoviral Vaccine Vectors Expressing Gag

Casimiro, Danilo R., Wang, Fubao, Schleif, William A., Liang, Xiaoping, Zhang, Zhi-Qiang, Tobery, Timothy W., ...

The prophylactic efficacy of DNA and replication-incompetent adenovirus serotype 5 (Ad5) vaccine vectors expressing simian immunodeficiency virus (SIV) Gag was examined in rhesus macaques using an...

Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag Gene

Casimiro, Danilo R., Chen, Ling, Fu, Tong-Ming, Evans, Robert K., Caulfield, Michael J., Davies, Mary-Ellen, ...

Cellular immune responses, particularly those associated with CD3+ CD8+ cytotoxic T lymphocytes (CTL), play a primary role in controlling viral infection, including persistent infection with human...

Vaccine-Induced Cellular Immune Responses Reduce Plasma Viral Concentrations after Repeated Low-Dose Challenge with Pathogenic Simian Immunodeficiency Virus SIVmac239

Wilson, Nancy A., Reed, Jason, Napoe, Gnankang S., Piaskowski, Shari, Szymanski, Andy, Furlott, Jessica, ...

The goal of an AIDS vaccine regimen designed to induce cellular immune responses should be to reduce the viral set point and preserve memory CD4 lymphocytes. Here we investigated whether...

Mamu-A∗01 Allele-Mediated Attenuation of Disease Progression in Simian-Human Immunodeficiency Virus Infection

Zhang, Zhi-Qiang, Fu, Tong-Ming, Casimiro, Danilo R., Davies, Mary-Ellen, Liang, Xiaoping, Schleif, William A., ...

Expression of several major histocompatibility complex (MHC) class I alleles is associated with a protective effect against disease progression in both human immunodeficiency virus type 1 and simian...

Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag Gene

Casimiro, Danilo R., Chen, Ling, Fu, Tong-Ming, Evans, Robert K., Caulfield, Michael J., Davies, Mary-Ellen, ...

Cellular immune responses, particularly those associated with CD3+ CD8+ cytotoxic T lymphocytes (CTL), play a primary role in controlling viral infection, including persistent infection with human...

Characterization of gp120 and Its Single-Chain Derivatives, gp120-CD4D12 and gp120-M9: Implications for Targeting the CD4i Epitope in Human Immunodeficiency Virus Vaccine Design

Varadarajan, Raghavan, Sharma, Deepak, Chakraborty, Kausik, Patel, Mayuri, Citron, Michael, Sinha, Prem, ...

Single-chain derivatives of JRFL gp120 linked to the first two domains of human CD4 (gp120-CD4D12) or to the CD4 miniprotein analog CD4M9 (gp120-M9), have been constructed. Biacore studies revealed...

Universal Influenza B Vaccine Based on the Maturational Cleavage Site of the Hemagglutinin Precursor

Bianchi, Elisabetta, Liang, Xiaoping, Ingallinella, Paolo, Finotto, Marco, Chastain, Michael A., Fan, Jiang, ...

Conventional influenza vaccines can prevent infection, but their efficacy depends on the degree of antigenic “match” between the strains used for vaccine preparation and those circulating in the...

Vectored Gag and Env but Not Tat Show Efficacy against Simian-Human Immunodeficiency Virus 89.6P Challenge in Mamu-A*01-Negative Rhesus Monkeys

Liang, Xiaoping, Casimiro, Danilo R., Schleif, William A., Wang, Fubao, Davies, Mary-Ellen, Zhang, Zhi-Qiang, ...

Simian-human immunodeficiency virus (SHIV) challenge studies in rhesus macaques were conducted to evaluate the efficacy of adenovirus-based vaccines in the context of different major...

Attenuation of Simian Immunodeficiency Virus SIVmac239 Infection by Prophylactic Immunization with DNA and Recombinant Adenoviral Vaccine Vectors Expressing Gag

Casimiro, Danilo R., Wang, Fubao, Schleif, William A., Liang, Xiaoping, Zhang, Zhi-Qiang, Tobery, Timothy W., ...

The prophylactic efficacy of DNA and replication-incompetent adenovirus serotype 5 (Ad5) vaccine vectors expressing simian immunodeficiency virus (SIV) Gag was examined in rhesus macaques using an...

Vaccine-Induced Cellular Immune Responses Reduce Plasma Viral Concentrations after Repeated Low-Dose Challenge with Pathogenic Simian Immunodeficiency Virus SIVmac239

Wilson, Nancy A., Reed, Jason, Napoe, Gnankang S., Piaskowski, Shari, Szymanski, Andy, Furlott, Jessica, ...

The goal of an AIDS vaccine regimen designed to induce cellular immune responses should be to reduce the viral set point and preserve memory CD4 lymphocytes. Here we investigated whether...

Design of immunogens that present the crown of the HIV-1 V3 loop in a conformation competent to generate 447-52D-like antibodies

Chakraborty, Kausik, Durani, Venuka, Miranda, Edward Roshan, Citron, Michael, Liang, Xiaoping, Schleif, William, ...

gp120 is a subunit of the envelope glycoprotein of HIV-1. The third variable loop region of gp120 (V3 loop) contains multiple immunodominant epitopes and is also functionally important for deciding...