「コラボレーション方式」による構成的エンカウンター・グループのファシリテーター養成の試み : を中心に (2007)
野島, 一彦, 桂木, 彩, 篠原, 光代, 二ノ宮, 英義, 原田, 絵美子, 吉田, 眞美, ...
This paper is a trial of the facilitator training for structured encounter group by using "Collaborative Method". Six facilitators facilitated a structured encounter group (8 sessions, 90 minutes,...
A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity. (2007)
Kim, Tae Whan, Staschke, Kirk, Bulek, Katarzyna, Yao, Jianhong, Peters, Kristi, Oh, Keun-Hee, ...
IRAK4 is a member of IL-1 receptor (IL-1R)-associated kinase (IRAK) family and has been shown to play an essential role in Toll-like receptor (TLR)-mediated signaling. We recently generated IRAK4...
LCI/MC INTERNATIONAL WORKSHOP ON “LOW-COST INSTRUMENTATION- (2002)
Xiaoxia Li, Yoshimasa Takahashi
As one of the FACS Projects, the major activities of Asian Chemical Information Network (ChIN) cab be summarized as: 1. Maintenance of the FACS Web Site Since the FACS Web site was officially...
Thesis (Ph. D.)--University of New Hampshire, 1993.
Li, Xiaoxia, Liao, Warren S.L.
Serum amyloid A (SAA) is a major acute-phase protein synthesized and secreted mainly by the liver. In response to inflammation, its expression is increased by 1000-fold, primarily because of a...
To understand how the serum amyloid A (SAA) genes are regulated, the cis-acting elements and trans-acting factors involved in the regulation of mouse SAA3 and rat SAA1 genes expression during...
Act1, an NF-κB-activating protein
Li, Xiaoxia, Commane, Mairead, Nie, Huiqin, Hua, Xianxin, Chatterjee-Kishore, Moitreyee, Wald, David, ...
Use of an NF-κB-dependent selectable marker facilitated the isolation of a cell line containing a cDNA encoding Act1, an NF-κB activator. Act1 associates with and activates IκB kinase (IKK),...
Li, Xiaoxia, Commane, Mairead, Jiang, Zhengfan, Stark, George R.
Mutant I1A cells, lacking IL-1 receptor-associated kinase (IRAK) mRNA and protein, have been used to study the involvement of IRAK in NFκB and c-Jun N-terminal kinase (JNK) activation. A series of...
Li, Xiaoxia, Commane, Mairead, Burns, Carmel, Vithalani, Kalpa, Cao, Zhaodan, Stark, George R.
Mutagenized human 293 cells containing an interleukin-1 (IL-1)-regulated herpes thymidine kinase gene, selected in IL-1 and gancyclovir, have yielded many independent clones that are unresponsive to...
Takaesu, Giichi, Ninomiya-Tsuji, Jun, Kishida, Satoshi, Li, Xiaoxia, Stark, George R., Matsumoto, Kunihiro
Interleukin-1 (IL-1) is a proinflammatory cytokine that recognizes a surface receptor complex and generates multiple cellular responses. IL-1 stimulation activates the mitogen-activated protein...
Jefferies, Caroline, Bowie, Andrew, Brady, Gareth, Cooke, Emma-Louise, Li, Xiaoxia, O'Neill, Luke A. J.
We have examined the involvement of components of the interleukin-1 (IL-1) signaling pathway in the transactivation of gene expression by the p65 subunit of NF-κB. Transient transfection of cells...
Role of NFκB activator Act1 in CD40-mediated signaling in epithelial cells
Qian, Youcun, Zhao, Zhendong, Jiang, Zhengfan, Li, Xiaoxia
CD40, a cell surface receptor in the tumor necrosis factor receptor family, first identified and functionally characterized on B lymphocytes, is also expressed on epithelial and other cells and is...
Jiang, Zhengfan, Ninomiya-Tsuji, Jun, Qian, Youcun, Matsumoto, Kunihiro, Li, Xiaoxia
Interleukin-1 (IL-1) receptor-associated kinase (IRAK) plays an important role in the sequential formation and activation of IL-1-induced signaling complexes. Previous studies showed that IRAK is...
Epstein–Barr virus latent membrane protein 1 activation of NF-κB through IRAK1 and TRAF6
Luftig, Micah, Prinarakis, Efthimios, Yasui, Teruhito, Tsichritzis, Theodore, Cahir-McFarland, Ellen, Inoue, Jun-Ichiro, ...
Epstein–Barr virus latent membrane protein 1 (LMP1) activation of NF-κB is critical for Epstein–Barr virus-infected B lymphocyte survival. LMP1 activates the IκB kinase complex and NF-κB...
Mutant human cells with constitutive activation of NF-κB
Sathe, Swati S., Sizemore, Nywana, Li, Xiaoxia, Vithalani, Kalpa, Commane, Mairead, Swiatkowski, Shannon M., ...
We have used a genetic approach to generate eight different mutant human cell lines in which NF-κB is constitutively activated. These independent clones have different phenotypes and belong to...
Identification of a human NF-κB-activating protein, TAB3
Jin, Ge, Klika, Alison, Callahan, Michelle, Faga, Ben, Danzig, Joel, Jiang, Zhengfan, ...
The NF-κB pathway plays a critical role in regulating cellular processes such as immune responses, stress responses, apoptosis, proliferation and differentiation, whereas dysfunction of this pathway...
Jiang, Zhengfan, Mak, Tak W., Sen, Ganes, Li, Xiaoxia
We have previously shown that double-stranded RNA-triggered, Toll-like receptor 3 (TLR3)-mediated signaling is independent of MyD88, IRAK4, and IRAK. Instead, TRAF6, TAK1, and TAB2 are recruited to...
Differential Role for TLR3 in Respiratory Syncytial Virus-Induced Chemokine Expression
Rudd, Brian D., Burstein, Ezra, Duckett, Colin S., Li, Xiaoxia, Lukacs, Nicholas W.
Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection in young infants worldwide. Previous studies have reported that the induction of interleukin-8/CXCL8 and...
CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri
Girardin, Stephen E., Tournebize, Régis, Mavris, Maria, Page, Anne-Laure, Li, Xiaoxia, Stark, George R., ...
Epithelial cells are refractory to extracellular lipopolysaccharide (LPS), yet when presented inside the cell, it is capable of initiating an inflammatory response. Using invasive Shigella flexneri...
Act1, an NF-κB-activating protein
Li, Xiaoxia, Commane, Mairead, Nie, Huiqin, Hua, Xianxin, Chatterjee-Kishore, Moitreyee, Wald, David, ...
Use of an NF-κB-dependent selectable marker facilitated the isolation of a cell line containing a cDNA encoding Act1, an NF-κB activator. Act1 associates with and activates IκB kinase (IKK),...
Li, Xiaoxia, Commane, Mairead, Jiang, Zhengfan, Stark, George R.
Mutant I1A cells, lacking IL-1 receptor-associated kinase (IRAK) mRNA and protein, have been used to study the involvement of IRAK in NFκB and c-Jun N-terminal kinase (JNK) activation. A series of...
Li, Xiaoxia, Commane, Mairead, Burns, Carmel, Vithalani, Kalpa, Cao, Zhaodan, Stark, George R.
Mutagenized human 293 cells containing an interleukin-1 (IL-1)-regulated herpes thymidine kinase gene, selected in IL-1 and gancyclovir, have yielded many independent clones that are unresponsive to...
Takaesu, Giichi, Ninomiya-Tsuji, Jun, Kishida, Satoshi, Li, Xiaoxia, Stark, George R., Matsumoto, Kunihiro
Interleukin-1 (IL-1) is a proinflammatory cytokine that recognizes a surface receptor complex and generates multiple cellular responses. IL-1 stimulation activates the mitogen-activated protein...
Jefferies, Caroline, Bowie, Andrew, Brady, Gareth, Cooke, Emma-Louise, Li, Xiaoxia, O'Neill, Luke A. J.
We have examined the involvement of components of the interleukin-1 (IL-1) signaling pathway in the transactivation of gene expression by the p65 subunit of NF-κB. Transient transfection of cells...
Role of NFκB activator Act1 in CD40-mediated signaling in epithelial cells
Qian, Youcun, Zhao, Zhendong, Jiang, Zhengfan, Li, Xiaoxia
CD40, a cell surface receptor in the tumor necrosis factor receptor family, first identified and functionally characterized on B lymphocytes, is also expressed on epithelial and other cells and is...
Jiang, Zhengfan, Ninomiya-Tsuji, Jun, Qian, Youcun, Matsumoto, Kunihiro, Li, Xiaoxia
Interleukin-1 (IL-1) receptor-associated kinase (IRAK) plays an important role in the sequential formation and activation of IL-1-induced signaling complexes. Previous studies showed that IRAK is...
Epstein–Barr virus latent membrane protein 1 activation of NF-κB through IRAK1 and TRAF6
Luftig, Micah, Prinarakis, Efthimios, Yasui, Teruhito, Tsichritzis, Theodore, Cahir-McFarland, Ellen, Inoue, Jun-Ichiro, ...
Epstein–Barr virus latent membrane protein 1 (LMP1) activation of NF-κB is critical for Epstein–Barr virus-infected B lymphocyte survival. LMP1 activates the IκB kinase complex and NF-κB...
Mutant human cells with constitutive activation of NF-κB
Sathe, Swati S., Sizemore, Nywana, Li, Xiaoxia, Vithalani, Kalpa, Commane, Mairead, Swiatkowski, Shannon M., ...
We have used a genetic approach to generate eight different mutant human cell lines in which NF-κB is constitutively activated. These independent clones have different phenotypes and belong to...
Identification of a human NF-κB-activating protein, TAB3
Jin, Ge, Klika, Alison, Callahan, Michelle, Faga, Ben, Danzig, Joel, Jiang, Zhengfan, ...
The NF-κB pathway plays a critical role in regulating cellular processes such as immune responses, stress responses, apoptosis, proliferation and differentiation, whereas dysfunction of this pathway...
Jiang, Zhengfan, Mak, Tak W., Sen, Ganes, Li, Xiaoxia
We have previously shown that double-stranded RNA-triggered, Toll-like receptor 3 (TLR3)-mediated signaling is independent of MyD88, IRAK4, and IRAK. Instead, TRAF6, TAK1, and TAB2 are recruited to...
Differential Role for TLR3 in Respiratory Syncytial Virus-Induced Chemokine Expression
Rudd, Brian D., Burstein, Ezra, Duckett, Colin S., Li, Xiaoxia, Lukacs, Nicholas W.
Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection in young infants worldwide. Previous studies have reported that the induction of interleukin-8/CXCL8 and...
CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri
Girardin, Stephen E., Tournebize, Régis, Mavris, Maria, Page, Anne-Laure, Li, Xiaoxia, Stark, George R., ...
Epithelial cells are refractory to extracellular lipopolysaccharide (LPS), yet when presented inside the cell, it is capable of initiating an inflammatory response. Using invasive Shigella flexneri...
A critical role for IRAK4 kinase activity in Toll-like receptor–mediated innate immunity
Kim, Tae Whan, Staschke, Kirk, Bulek, Katarzyna, Yao, Jianhong, Peters, Kristi, Oh, Keun-Hee, ...
IRAK4 is a member of IL-1 receptor (IL-1R)–associated kinase (IRAK) family and has been shown to play an essential role in Toll-like receptor (TLR)–mediated signaling. We recently generated IRAK4...
Ku, Cheng-Lung, Von Bernuth, Horst, Picard, Capucine, Zhang, Shen-Ying, Chang, Huey-Hsuan, Yang, Kun, ...
Human interleukin (IL) 1 receptor–associated kinase 4 (IRAK-4) deficiency is a recently discovered primary immunodeficiency that impairs Toll/IL-1R immunity, except for the Toll-like receptor (TLR)...
Pellino 3b Negatively Regulates Interleukin-1-induced TAK1-dependent NFκB Activation*S⃞
Xiao, Hui, Qian, Wen, Staschke, Kirk, Qian, Youcun, Cui, Grace, Deng, Li, ...
IL-1 receptor-associated kinase (IRAK) is phosphorylated, ubiquitinated, and degraded upon interleukin-1 (IL-1) stimulation. In this study, we showed that IRAK can be ubiquitinated through both...
Frączek, Jerzy, Kim, Tae Whan, Xiao, Hui, Yao, Jianhong, Wen, Qian, Li, Yali, ...
Two parallel interleukin-1 (IL-1)-mediated signaling pathways have been uncovered for IL-1R-TLR-mediated NFκB activation: TAK1-dependent and MEKK3-dependent pathways, respectively. The...