A Concrete Estimate For The Weak Poincare Inequality On Loop Space (2009)
Chen, Xin, Li, Xue-Mei, Wu, Bo
The aim of the paper is to study the pinned Wiener measure on the loop space over a simply connected compact Riemannian manifold together with the Hilbert space structure induced by Mallianvin...
High level architecture evolved modular federation object model (2009)
Wang, Wenguang, Xu, Yongping, Chen, Xin, Li, Qun, Wang, Weiping
To improve the agility, dynamics, composability, reusability, and development efficiency restricted by monolithic Federation Object Model (FOM), a modular FOM was proposed by High Level Architecture...
Qiu, Zhibing, Chen, Xin, Xu, Ming, Jiang, Yingshuo, Xiao, Liqiong, Liu, LeLe, ...
Abstract Background The purpose of the present study was to evaluate the safety and the cost-effectiveness of using preoperative IABP as support compared with postoperative IABP treatment in coronary...
Game Characterizations of Process Equivalences (2009)
Abstract. In this paper we propose a hierarchy of games that allows us to make a systematic comparison of process equivalences by characterizing process equivalences as games. The well-known...
A Poincar\'e Inequality on Loop Spaces (2009)
Chen, Xin, Li, Xue-Mei, Wu, Bo
We investigate properties of measures in infinite dimensional spaces in terms of Poincar\'e inequalities. A Poincar\'e inequality states that the $L^2$ variance of an admissible function is...
W. Bowyer, Fellow Ieee, Kyong I. Chang, Patrick J. Flynn, Senior Member Ieee, Xin Chen
Use of multiple images of a face appears to improve recognition accuracy regardless of the type of images that are taken.
Chengcui Zhang, Xin Chen, Wei-bang Chen
The proposed system is a region based semantic image retrieval system. The retrieval is realized through mapping and solving a Multiple Instance Learning (MIL) problem [1]. MIL is a supervised...
PROFESSIONAL EXPERIENCE (2009)
To obtain a challenging position in Software Development, where I can utilize and enhance my
Yili Zhang, Xiaoyan Huang, Hongwen Du, Yun Zhang, Xin Chen, Peng Wang, ...
Abstract Background To define a threshold value of apparent diffusion coefficient (ADC) with which malignant breast lesions can be distinguished from benign lesions, and to evaluate the ADC change of...
Analytical Path to Improved RF Field Homogeneity for High Field MRI (2009)
The focus of this dissertation is on the finite RF (radio frequency) wavelength effect in high field MRI (magnetic resonance imaging). As the RF frequency increases proportionally with the main...
Analytical Path to Improved RF Field Homogeneity for High Field MRI (2009)
The focus of this dissertation is on the finite RF (radio frequency) wavelength effect in high field MRI (magnetic resonance imaging). As the RF frequency increases proportionally with the main...
Qing-An Qiao, Xiao-Min Sun, Jie Jing, Xin Chen, Hua-Yang Wang, Chuan-Lu Yang, ...
The acetylation mechanisms of several selected typical substrates from experiments, including arylamines and arylhydrazines, are investigated with the density functional theory in this paper. The...
Qing-An Qiao, Xiao-Min Sun, Jie Jing, Xin Chen, Hua-Yang Wang, Chuan-Lu Yang, ...
The acetylation mechanisms of several selected typical substrates from experiments, including arylamines and arylhydrazines, are investigated with the density functional theory in this paper. The...
Cheng, Min, Hua, Wei, Chen, Keping, Pu, Jielin, Ren, Xiaoqing, Zhao, Xinran, ...
Aims This study was to evaluate perioperative anticoagulation therapy in patients with mechanic heart valve(s) undergoing pacemaker implantation. Methods and resluts A total of 109 patients with...
Charles Michael Drain, Kenneth S. Suslick, R. Wasielewski, Xin Chen
A perspective on four new porphyrin-based functional
Li Ou, Xin Chen, Xubin (ben He, Christian Engelmann, Stephen L. Scott
Cluster computing has become one of the most popular platforms for high-performance computing today. The recent popularity of multicore processors provides a flexible way to increase the...
Maintaining Strong Cache Consistency for the Domain Name System (2008)
Xin Chen, Haining Wang, Shansi Ren, Student Member, Xiaodong Zhang
(DNS) is critical to its performance and scalability. Existing DNS only supports weak cache consistency by using the Time-To-Live (TTL) mechanism, which functions reasonably well in normal...
Xin Chen, R. Kimberley Cook, Peter A. Rubenstein
44-49) hypothesized that between subdomains 3 and 4 of actin is a loop of 10 amino acids including a four residue hydrophobic plug that inserts into a hydropho-bic pocket formed by two adjacent...
This paper presents a methodology for personalized knowledge discovery from text. It derives a user’s background knowledge from his/her background documents, and exploits such knowledge to evaluate...
DNScup: Strong Cache Consistency Protocol for DNS (2008)
Haining Wang 2 Effective caching in Domain Name System (DNS) is critical to its performance and scalability. Existing DNS only supports weak cache consistency by using the Time-To-Live (TTL)...
Automatic in vivo Microscopy Video Mining for Leukocytes (2008)
Chengcui Zhang, Wei-bang Chen, Lin Yang, Xin Chen, John K. Johnstone
Biological videos are very different from conventional videos. Automatic spatiotemporal mining of moving cells from in vivo microscopy videos is extremely difficult because of the severe noises,...
potential mechanisms of (2008)
Xin Chen, Choong Yong Ung, Yuzong Chen, Xin Chen, Yuzong Chen, Ung Choong Yong, ...
an in silico drug-target search method be used to probe
A Hybrid Classifier Approach for Web Retrieved Documents Classification Abstract (2008)
Razvan Stefan Bot, Xin Chen, Quanzhi Li
The paper presents a hybrid technique for the classification of web returned hits into concept hierarchies. The technique involves a combination of manual and automatic classifiers. At first, all web...
Quanzhi Li, Razvan Stefan Bot, Xin Chen
With the pervasion of digital textual data, text mining is becoming more and more important to deriving competitive advantages. One factor for successful text mining applications is the ability of...
This paper presents a methodology for personalized knowledge discovery from text. It derives a user’s background knowledge from his/her background documents, and exploits such knowledge to evaluate...
Research on distance learning and computer-aided grading has been developed in parallel. Little work has been done in the past to join the two areas to solve the problem of automated learning...
Quanzhi Li, Razvan Stefan Bot, Xin Chen
Effectiveness and efficiency of searching and returned results presentation is the key to a search engine. Before downloading and examining the document text, users usually first judge the relevance...
Kyong I. Chang, Kevin W. Bowyer, Patrick J. Flynn, Xin Chen
We present results of the first study to examine individual and multi-modal face recognition using 2D, 3D and infrared images of the same set of subjects. Each sensor captures different aspects of...
Duality Approaches to Economic Lot-Sizing Games ∗ (2008)
We consider the economic lot-sizing (ELS) game with general concave ordering cost. In this cooperative game, multiple retailers form a coalition by placing joint orders to a single supplier in order...
A Procedure Search Mechanism in OGSA-Based GridRPC Systems (2008)
Yue-zhuo Zhang, Yong-zhong Huang, Xin Chen, Zhengzhou Henan China
Abstract. This paper presents a way of searching remote procedures in OGSAbased GridRPC systems. GGF recommends a grid-enabled, remote procedure call mechanism (GridRPC) to provide a low barrier to...
Heuristics for Image Retrieval Using Spatial Configurations ⋆ (2008)
W. F. Smyth, C. P. Lam, Xin Chen, Valerie Maxville
Abstract. This paper describes a strategy for content-based image retrieval via spatial configuration of objects within an image. The proposed strategy locates “pattern ” images within “text...
DOI 10.1007/s00894-007-0178-7 (2008)
Xin Chen, Yuefan Deng, X. Chen
Long-time molecular dynamics simulations of botulinum biotoxin type-A at different pH values and temperatures
Li Ou, Xin Chen, Xubin (ben He, Christian Engelmann, Stephen L. Scott
Cluster computing has become one of the most popular platforms for high-performance computing today. The recent popularity of multicore processors provides a flexible way to increase the...
Simulations of a specific inhibitor of the disheveled PDZ domain (2008)
The Dishevelled (Dvl) PDZ domain is believed to play an essential roles in the canonical and noncanonical Wnt signaling pathways, which are involved in embryo development as well as in tumorigenesis....
Maintaining Strong Cache Consistency for the Domain Name System (2008)
Xin Chen, Haining Wang, Shansi Ren, Student Member, Xiaodong Zhang, Senior Member
Abstract—Effective caching in the Domain Name System (DNS) is critical to its performance and scalability. Existing DNS only supports weak cache consistency by using the Time-to-Live (TTL)...
Xin Chen, Chengcui Zhang, Shu-ching Chen, Min Chen
Relevance Feedback (RF) is a widely used technique in incorporating user’s knowledge with the learning process for Content-Based Image Retrieval (CBIR). As a supervised learning technique, it has...
DNScup: Strong Cache Consistency Protocol for DNS (2008)
Xin Chen Ask, Xin Chen, Shansi Ren
Effective caching in Domain Name System (DNS) is critical to its performance and scalability. Existing DNS only supports weak cache consistency by using the Time-To-Live (TTL) mechanism, which...
This dissertation studies the competition between two e-auction marketplaces using computer simulations. The simulation answers questions of whether the evolution of the market converges to market...
An Antenna-Theory Method for Modeling High-Frequency RF Coils: A Segmented Birdcage Example (2008)
Xin Chen, Victor Taracila, Timothy Eagan, Hiroyuki Fujita, Xingxian Shou, Tanvir Baig, ...
We suggest that center-fed dipole antenna analytics can be employed in the optimized design of high-frequency MRI RF coil applications. The method is illustrated in the design of a single-segmented...
3-Methoxy-4-(4-nitrobenzyloxy)benzaldehyde (2008)
In the title compound, C15H13NO5, the vanillin group makes a dihedral angle of 4.95 (8)° with the benzene ring of the nitrobenzene group. The packing is stabilized by weak, non-classical...
In the title compound, C24H20BrN3O4S, the central benzene ring makes dihedral angles of 24.55 (8), 49.52 (12) and 59.65 (7)°, respectively, with the pyrazolone ring, the...
Abstract The dishevelled (Dvl) PDZ domain is believed to play an essential role in the canonical and noncanonical Wnt signaling pathways, which are involved in embryo development as well as in...
An Antenna-Theory Method for Modeling High-Frequency RF Coils: A Segmented Birdcage Example (2008)
Xin Chen, Victor Taracila, Timothy Eagan, Hiroyuki Fujita, Xingxian Shou, Tanvir Baig, ...
We suggest that center-fed dipole antenna analytics can be employed in the optimized design of high-frequency MRI RF coil applications. The method is illustrated in the design of a single-segmented...
PlantTFDB: a comprehensive plant transcription factor database (2008)
Guo, An-Yuan, Chen, Xin, Gao, Ge, Zhang, He, Zhu, Qi-Hui, Liu, Xiao-Chuan, ...
Transcription factors (TFs) play key roles in controlling gene expression. Systematic identification and annotation of TFs, followed by construction of TF databases may serve as useful resources for...
Chen, Xin, Guo, Lingqiong, Fan, Zhaocheng, Jiang, Tao
Motivation: Position weight matrices (PWMs) are widely used to depict the DNA binding preferences of transcription factors (TFs) in computational molecular biology and regulatory genomics. Thus,...
Functional Organization of Temporal Frequency Selectivity in Primate Visual Cortex (2008)
Khaytin, Ilya, Chen, Xin, Royal, David W., Ruiz, Octavio, Jermakowicz, Walter J., Siegel, Ralph M., ...
Several studies have shown that neurons with similar response properties are arranged together in domains across primary visual cortex (V1). An orderly pattern of domains has been described for...
A Novel Fast-Lock-in Digitally Controlled Phase-Locked Loop (2008)
CHEN, Xin, YANG, Jun, SHI, Long-xing
A novel fast lock-in digitally controlled phase-locked loop (DCPLL) is proposed in this letter. This DCPLL adopts a novel frequency search algorithm to reduce the lock-in time. Furthermore, to reduce...
Construction of larger Riemannian metrics with bounded sectional curvatures and applications (2008)
For any (not necessarily complete) Riemannian manifold, we construct a larger Riemannian metric which is complete and with bounded sectional curvatures. As an application, log-Sobolev inequalities...
We present a lossless compression algorithm, GenCompress, for genetic sequences, based on searching for approximate repeats. Our algorithm achieves the best compression ratios for benchmark DNA...
Existing prefetching techniques rely on server-based, proxybased, or client-based reference access information. Although Web servers may provide accurate access information, our studies show that...
A Stochastic Programming Duality Approach to Inventory Centralization Games (2007)
In this paper, we present a unified approach to study a class of cooperative games arising from inventory centralization. The optimization problems corresponding to the inventory games are formulated...
A Stochastic Programming Duality Approach to Inventory Centralization Games (2007)
In this paper, we present a unified approach to study a class of cooperative games arising from inventory centralization. The optimization problems corresponding to the inventory games are formulated...
Duality Approaches to Economic Lot-Sizing Games (2007)
We consider the economic lot-sizing (ELS) game with general concave ordering cost. In this cooperative game, multiple retailers form a coalition by placing joint orders to a single supplier in order...
Duality Approaches to Economic Lot-Sizing Games (2007)
We consider the economic lot-sizing (ELS) game with general concave ordering cost. In this cooperative game, multiple retailers form a coalition by placing joint orders to a single supplier in order...
MRI MONITORING AND MODEL PREDICTION OF THERMAL ABLATION DYNAMICS IN TISSUE (2007)
This research is motivated by the need for more effective and efficient clinical application of minimally invasive thermal ablation of solid tumors. During the ablation procedure, it is important to...
MRI MONITORING AND MODEL PREDICTION OF THERMAL ABLATION DYNAMICS IN TISSUE (2007)
This research is motivated by the need for more effective and efficient clinical application of minimally invasive thermal ablation of solid tumors. During the ablation procedure, it is important to...
DEVELOPMENT AND ACHIEVEMENTS OF CHINA'S INTELLECTUAL PROPERTY PROTECTION UNDER GLOBALIZATION (2007)
With China's open door policy in the late of 1978 and accession to the World Trade Organization in 2001, the progress of globalization has accelerated the comprehensive development of China's...
Zhi Qun Tang, Hong Huang Lin, Hai Lei Zhang, Lian Yi Han, Xin Chen, Yu Zong Chen
Various computational methods have been used for the prediction of protein and peptide function based on their sequences. A particular challenge is to derive functional properties from sequences that...
The Grid Resource Discovery Method Based on Hierarchical Model (2007)
Yulan Yin, Huanqing Cui, Xin Chen
Grid is considered as next generation network and resource discovery is a basic component of Grid resource management. This study presents a hierarchical resource discovery method to make use of...
Separation of Concerns and Consistent Integration in Requirements Modelling (2007)
Xin Chen, Zhiming Liu, Vladimir Mencl
Abstract. Due to their increasing complexity, design of software systems is not becoming easier. Furthermore, modern applications ranging from enterprise to embedded systems require very high levels...
Shansi Ren, Student Member, Qun Li, Haining Wang, Xin Chen, Xiaodong Zhang, ...
Abstract—Object detection quality and network lifetime are two conflicting aspects of a sensor network, but both are critical to many sensor applications such as military surveillance. Partial...
Symmetric active/active metadata service for highly available cluster storage systems (2007)
Li Ou, Christian Engelmann, Xubin He, Xin Chen, Stephen Scott
In a typical distributed storage system, metadata is stored and managed by dedicated metadata servers. One way to improve the availability of distributed storage systems is to deploy multiple...
Small Covers over Prisms (2006)
Cai, Mingzhong, Chen, Xin, Lü, Zhi
In this paper we calculate the number of equivariant diffeomorphism classes of small covers over a prism.
Cartesian P-property and its applications to the semidefinite linear complementarity problem (2006)
We introduce a Cartesian P-property for linear transformations between the space of symmetric matrices and present its applications to the semidefinite linear complementarity problem (SDLCP). With...
Spatially extended nature of resistive switching in perovskite oxide thin films (2006)
Chen, Xin, Wu, NaiJuan, Strozier, John, Ignatiev, Alex
We report the direct observation of the electric pulse induced resistance-change (EPIR) effect at the nano scale on La1-xSrxMnO3 (LSMO) thin films by the current measurement AFM technique. After a...
Ordered arrays of mesoporous microrods from recyclable macroporous silicon templates (2006)
Chen, Xin, Steinhart, Martin, Hess, Christian, Gösele, Ulrich
Dependence and the copula approach (2006)
Project (M.A.) - Faculty of Business Administration - Simon Fraser University
A Spatio-temporal Database Model for (2006)
Transportation Surveillance Videos, Xin Chen, Chengcui Zhang
� There is a proliferation of transportation surveillance videos. � With object tracking techniques, trajectories of vehicles can be extracted. Analysis focuses on the spatiotemporal
International Institute for Software Technology Component Coordination in rCOS (2006)
Xin Chen, Jifeng He, Zhiming Liu
Republic of China and Portugal through a contribution to the UNU Endownment Fund. As well as providing twothirds of the endownment fund, the Macau authorities also supply UNU-IIST with its office...
International Institute for Software Technology A Model of Component-Based Programming (2006)
Xin Chen, He Jifeng, Zhiming Liu, Naijun Zhan
Centre of the United Nations University (UNU). It is based in Macao, and was founded in 1991. It started operations in July 1992. UNU-IIST is jointly funded by the government of Macao and the...
ANALYSIS OF FACIAL RECOGNITION OVER MULTIPLE MODALITIES (2006)
Xin Chen, Patrick J. Flynn, Kevin W. Bowyer
typeset with nddiss2ε v1.0 (2004/06/15) on July 26, 2006 for
c ○ Imperial College Press A GENERAL FRAMEWORK FOR BICLUSTERING GENE EXPRESSION DATA (2006)
Haifeng Li, Xin Chen, Keshu Zhang, Tao Jiang
A large number of biclustering methods have been proposed to detect patterns in gene expression data. All these methods try to find some type of biclusters but no one can discover all the types of...
Krishnamoorthy, Thanuja, Chen, Xin, Govin, Jerome, Cheung, Wang L., Dorsey, Jean, Schindler, Karen, ...
Sporulation in Saccharomyces cerevisiae is a highly regulated process wherein a diploid cell gives rise to four haploid gametes. In this study we show that histone H4 Ser1 is phosphorylated (H4 S1ph)...
Optimal Integrability Condition for the log-Sobolev inequality (2006)
Let M denote a connected complete Riemannian manifold (possibly with a convex boundary), ρ the Riemannian distance function from a fixed point and V ∈ C2(M) such that dµV ≔ eV dx is a...
Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours (2006)
Guo, Dong Li, Zhang, Ji, Yuen, Siu Tsan, Tsui, Wai Yin, Chan, Annie S.Y., Ho, Coral, ...
EphB2, a receptor tyrosine kinase regulated by the β-catenin/Tcf4 complex, is expressed in the proliferative compartment of mouse intestine and regulates bidirectional migration of intestinal...
TiProD: the Tissue-specific Promoter Database (2006)
Chen, Xin, Wu, Jian-min, Hornischer, Klaus, Kel, Alexander, Wingender, Edgar
TiProD is a database of human promoter sequences for which some functional features are known. It allows a user to query individual promoters and the expression pattern they mediate, gene expression...
Buffer-Enhanced Electrical-Pulse-Induced-Resistive Memory Effect in Thin Film Perovskites (2005)
Chen, Xin, Wu, Naijuan, Ignatiev, Alex, Chen, Qing, Zhang, Yue
A multilayer perovskite thin film resistive memory device has been developed comprised of: a Pr0.7Ca0.3MnO3 (PCMO) perovskite oxide epitaxial layer on a YBCO bottom thin film electrode; a thin yttria...
Furge, Kyle A, Dykema, Karl J, Ho, Coral, Chen, Xin
Abstract Background Regional expression biases (REBs) are genetic intervals where gene expression is coordinately changed. For example, if a region of the genome is amplified, often the majority of...
Mutations of PIK3CAin gastric adenocarcinoma (2005)
Li, Vivian, Wong, Chi, Chan, Tsun, Chan, Agnes, Zhao, Wei, Chu, Kent-Man, ...
Abstract Background Activation of the phosphatidylinositol 3-kinase (PI3K) through mutational inactivation of PTEN tumour suppressor gene is common in diverse cancer types, but rarely reported in...
Development of vocal protest from 3 to 18 months (2005)
Cry sounds change in both form and function during infancy. The present study investigated how cry sounds are used, not to request care, but to protest maternal behaviors. Infants' vocal protests of...
Surface composition of a series of segmented poly(siloxane urea urethane)'s have been determined by angle- and energy-dependent ESCA. The polymers are based on aminopropyl end-capped dimethylsiloxane...
Therodynamics, kinectics of ion-molecule reactions and solvation effects / (2005)
Chen, Xin., Brauman, John I. Advisor
Submitted to the Department of Chemistry.
A Robust Optimization Perspective Of Stochastic Programming (2005)
Xin Chen, Melvyn Sim, Peng Sun
In this paper, we introduce an approach for constructing uncertainty sets for robust optimization using new deviation measures for bounded random variables known as the forward and backward...
The role of top-down and bottom-up processes in guiding eye movements during visual search (2005)
Gregory J. Zelinsky, Wei Zhang, Bing Yu, Xin Chen, Dimitris Samaras
To investigate how top-down (TD) and bottom-up (BU) information is weighted in the guidance of human search behavior, we manipulated the proportions of BU and TD components in a saliency-based model....
Analyzing object detection quality under probabilistic coverage in sensor networks (2005)
Shansi Ren, Qun Li, Haining Wang, Xin Chen, Xiaodong Zhang
Abstract. Object detection quality and network lifetime are two conflicting aspects of a sensor network, but both are critical to many sensor applications such as military surveillance. Probabilistic...
Assignment of orthologous genes via genome rearrangement (2005)
Xin Chen, Jie Zheng, Zheng Fu, Peng Nan, Yang Zhong, Stefano Lonardi, ...
Abstract—The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics. Existing methods that assign orthologs based on the...
Bowyer: Fully Automated Facial Symmetry Axis Detection (2005)
Xin Chen, Patrick J. Flynn, Kevin W. Bowyer
In this paper, we consider the problem of automatically detecting a facial symmetry axis in what we will call a standard human face image (acquired when the subject is looking directly into the...
IR and visible light face recognition (2005)
Xin Chen, Patrick J. Flynn, Kevin W. Bowyer
This paper presents the results of several large-scale studies of face recognition employing visible-light and infrared (IR) imagery in the context of principal component analysis. We find that in a...
Coordinated data prefetching for web contents (2005)
With the development of active proxy, the functions of a proxy have been enhanced beyond simply storing Web contents. Web prefetching activity in proxy is such an example to reduce client-perceived...
A Study on Object Tracking Quality under Probabilistic Coverage in Sensor Networks (2005)
Shansi Ren Qun, Qun Li, Haining Wang, Xin Chen, Xiaodong Zhang
Introduction Sensor networks are used for a wide range of object tracking applications, such as vehicle tracking in military surveillance and wild animal tracking in habitat monitoring [1]. These...
Analyzing Object Detection Quality Under (2005)
Probabilistic Coverage In, Shansi Ren, Qun Li, Haining Wang, Xin Chen, Xiaodong Zhang
Object detection quality and network lifetime are two conflicting aspects of a sensor network, but both are critical to many sensor applications such as military surveillance. Probabilistic coverage...
Assignment of orthologous genes via genome rearrangement (2005)
Xin Chen, Jie Zheng, Zheng Fu, Peng Nan, Yang Zhong, Stefano Lonardi, ...
Abstract—The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics. Existing methods that assign orthologs based on the...
The role of top-down and bottom-up processes in guiding eye movements during visual search (2005)
Gregory J. Zelinsky, Wei Zhang, Bing Yu, Xin Chen, Dimitris Samaras
To investigate how top-down (TD) and bottom-up (BU) information is weighted in the guidance of human search behavior, we manipulated the proportions of BU and TD components in a saliency-based model....
Chengcui Zhang, Xin Chen, Min Chen, Shu-ching Chen, Mei-ling Shyu
Multiple Instance Learning (MIL) is a special kind of supervised learning problem that has been studied actively in recent years. In this paper, we propose an approach based on One-Class Support...
SCOPE: Scalable Consistency Maintenance in Structured P2P Systems (2005)
Xin Chen, Shansi Ren, Haining Wang, Xiaodong Zhang
While current Peer-to-Peer (P2P) systems facilitate static file sharing, newly-developed applications demand that P2P systems be able to manage dynamically-changing files. Maintaining consistency...
Analyzing object detection quality under probabilistic coverage in sensor networks (2005)
Shansi Ren, Qun Li, Haining Wang, Xin Chen, Xiaodong Zhang
Abstract. Object detection quality and network lifetime are two conflicting aspects of a sensor network, but both are critical to many sensor applications such as military surveillance. Probabilistic...
IR and visible light face recognition (2005)
Xin Chen, Patrick J. Flynn, Kevin W. Bowyer
This paper presents the results of several large-scale studies of face recognition employing visible light and infra-red (IR) imagery in the context of principal component analysis. We find that in a...
doi:10.1093/nar/gkj113 TiProD: the Tissue-specific Promoter Database (2005)
Xin Chen, Jian-min Wu, Klaus Hornischer, Er Kel, Edgar Wingender
TiProD is a database of human promoter sequences for which some functional features are known. It allows a user to query individual promoters and the expression pattern they mediate, gene expression...
"A dissertation submitted to the Graduate Faculty in Biochemistry ..."
Patil, Mohini A., Gütgemann, Ines, Zhang, Ji, Ho, Coral, Cheung, Siu-Tim, Ginzinger, David, ...
Hepatocellular carcinoma (HCC) is one of the major malignancies worldwide. We have previously characterized global gene expression patterns in HCC using microarrays. Here, we report the analysis of...
Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumors (2005)
Guo, Dong Li, Zhang, Ji, Yuen, Siu Tsan, Tsui, Wai Yin, Chan, Annie S. Y., Ho, Coral, ...
EphB2, a receptor tyrosine kinase regulated by the β-catenin/Tcf4 complex, is expressed in the proliferative compartment of mouse intestine and regulates bidirectional migration of intestinal...
Patil, Mohini A., Gütgemann, Ines, Zhang, Ji, Ho, Coral, Cheung, Siu-Tim, Ginzinger, David, ...
Hepatocellular carcinoma (HCC) is one of the major malignancies worldwide. We have previously characterized global gene expression patterns in HCC using microarrays. Here, we report the analysis of...
We analyze a finite horizon, single product, periodic review model in which pricing and production/inventory decisions are made simultaneously. Demands in different periods are random variables that...
We analyze an infinite horizon, single product, periodic review model in which pricing and production/inventory decisions are made simultaneously. Demands in different periods are identically...
Risk Aversion in Inventory Management (2004)
Chen, Xin, Sim, Melvyn, Simchi-Levi, David, Sun, Peng
Traditional inventory models focus on risk-neutral decision makers, i.e., characterizing replenishment strategies that maximize expected total profit, or equivalently, minimize expected total cost...
Risk Aversion in Inventory Management (2004)
Chen, Xin, Sim, Melvyn, Simchi-Levi, David, Sun, Peng
Traditional inventory models focus on risk-neutral decision makers, i.e., characterizing replenishment strategies that maximize expected total profit, or equivalently, minimize expected total cost...
We analyze an infinite horizon, single product, periodic review model in which pricing and production/inventory decisions are made simultaneously. Demands in different periods are identically...
We analyze a finite horizon, single product, periodic review model in which pricing and production/inventory decisions are made simultaneously. Demands in different periods are random variables that...
Smooth convex approximation to the maximum eigenvalue function (2004)
Chen, Xin, Qi, Houduo, Qi, Liqun, Teo, Kok-Lay
In this paper, we consider smooth convex approximations to the maximum eigenvalue function. To make it applicable to a wide class of applications, the study is conducted on the composite function of...
Li, Ming, Chen, Xin, Li, Xin, Ma, Bin, Vitanyi, Paul M.B.
A new class of metrics appropriate for measuring effective similarity relations between sequences, say one type of similarity per metric, is studied. We propose a new ``normalized information...
Shared Information and Program Plagiarism Detection (2004)
Xin Chen, Brent Francia, Ming Li, Brian Mckinnon, Amit Seker
A fundamental question in information theory and in computer science is how to measure similarity or the amount of shared information between two sequences. We have proposed a metric, based on...
Computational Prediction of Operons in Synechococcus sp. WH8102 (2004)
Synechococcus Sp. Wh, Xin Chen, Zhengchang Su, Ying Xu, Tao Jiang
We computationally predict operons in the Synechococcus sp. WH8102 genome based on three types of genomic data: intergenic distances, COG gene functions and phylogenetic profiles. In the proposed...
PROP: a Scalable and Reliable P2P Assisted Proxy Streaming System (2004)
Lei Guo Songqing, Lei Guo, Songqing Chen, Shansi Ren, Xin Chen, Song Jiang
The demand of delivering streaming media content in the Internet has become increasingly high for scientific, educational, and commercial applications. Three representative technologies have been...
Risk aversion in inventory management (2004)
Xin Chen, Melvyn Sim, David Simchi-levi, Peng Sun
Traditional inventory models focus on risk-neutral decision makers, i.e., characterizing replenishment strategies that maximize expected total profit, or equivalently, minimize expected total cost...
CHEN, XIN, MOHR, GEORG, LAMBOWITZ, ALAN M.
The Neurospora crassa mitochondrial tyrosyl-tRNA synthetase (CYT-18 protein) promotes the splicing of group I introns by stabilizing the catalytically active RNA structure. To accomplish this, CYT-18...
Detection of bone fragments and other physical contaminations in deboned poultry meat has become increasingly important to ensure food quality and safety. Traditional X-ray imaging detection...
Detection of bone fragments and other physical contaminations in deboned poultry meat has become increasingly important to ensure food quality and safety. Traditional X-ray imaging detection...
Chen, Xin, Qi, Houduo, Tseng, Paul
For any function f from $\mathbb R$ to $\mathbb R$, one can define a corresponding function on the space of n × n (block-diagonal) real symmetric matrices by applying f to the eigenvalues of the...
The patentability of computer programs / (2003)
Thesis (LL. M.) Information Technology, Media, and E-Commerce, Dept. of Law -- University of Essex, 2003.
PCA-based face recognition in infrared imagery : baseline and comparative studies / (2003)
Thesis (M.S.C.S.E.)--University of Notre Dame, 2003.
Zugl.: Aachen, Techn. Hochsch., Diss., 2003.
Ming Li, Xin Chen, Xin Li, Bin Ma
Abstract — A new class of distances appropriate for measuring similarity relations between sequences, say one type of similarity per distance, is studied. We propose a new “normalized information...
Ming Li, Xin Chen, Xin Li, Bin Ma
Abstract—A new class of distances appropriate for measuring similarity relations between sequences, say one type of similarity per distance, is studied. We propose a new “normalized information...
Zhengchang Su, Phuongan Dam, Xin Chen, Victor Olman, Tao Jiang, Brian Palenik, ...
We present a computational protocol for inference of regulatory and signaling pathways in a microbial cell, through literature search, mining "high-throughput" biological data of various...
Accurately Modeling Workload Interactions for Deploying Prefetching in Web Servers (2003)
Although Web prefetching is regarded as an effective method to improve client access performance, the associated overhead prevents it from being widely deployed. Specifically, a major weakness in...
Variation in gene expression patterns in human gastric cancers (2003)
Xin Chen, Suet Y. Leung, Siu T. Yuen, Kent-man Chu, Jiafu Ji, Rui Li, ...
‡ These authors contributed equally to this work Correspondence should be addressed to: P.O.B
Thesis (Ph. D.)--University of Texas at Austin, 2002.
The ontogeny of vocal protest in the second half year / (2002)
Chen, Xin., Gustafson, Gwen E.
Thesis (M.A.)--University of Connecticut, 2003.
Targeting model drug carriers to irradiated endothelium / (2002)
Thesis (Ph. D.)--University of Tennessee, Memphis, 2002.
Thesis (Ph. D.)--University of Texas at Austin, 2002.
Thesis (Ph. D.)--University of Texas at Austin, 2002.
Analysis of Nonsmooth Vector-Valued Functions Associated with Second-Order Cones (2002)
Jein-shan Chen, Xin Chen, Paul Tseng
Let K be the Lorentz/second-order cone in IR . For any function f from IR to IR, one can de ne a corresponding function f (x) on IR by applying f to the spectral values of the spectral decomposition...
A Theory of Uncheatable Program Plagiarism Detection and Its Practical Implementation (2002)
Xin Chen, Ming Li, Brian Mckinnon, Amit Seker
This paper introduces a metric to measure the degree to which two computer programs are similar for plagiarism detection. This similarity metric is based on Kolmogorov complexity [8] and measures the...
DNACompress: fast and effective DNA sequence compression (2002)
Chen, Xin, Li, Ming, Ma, Bin, Tromp, John
Summary: While achieving the best compression ratios for DNA sequences, our new DNACompress program significantly improves the running time of all previous DNA compression programs. Availability:...
Li, Ming, Chen, Xin, Li, Xin, Ma, Bin, Vitanyi, Paul
A new class of distances appropriate for measuring similarity relations between sequences, say one type of similarity per distance, is studied. We propose a new ``normalized information distance'',...
Effect of uracil incorporation on the precision of HIV-1 (+)-strand DNA initiation. (2001)
Retroviruses have means to limit the accumulation of uracil in DNA strands, suggesting that uracil affects one or more steps in the viral life cycle. In this work, the effects of uracilated DNA were...
Effect of uracil incorporation on the precision of HIV-1 (+)-strand DNA initiation. (2001)
Retroviruses have means to limit the accumulation of uracil in DNA strands, suggesting that uracil affects one or more steps in the viral life cycle. In this work, the effects of uracilated DNA were...
Thesis (M.S.)--Dept. of Biochemistry, University of Utah, 2001.
Thesis (Ph. D.)--University of Texas at Austin, 2001.
Thesis (Ph. D.)--University of Texas at Austin, 2001.
Thesis (M.Sc.) -- McMaster University, 2001.
Thesis (Ph. D.)--University of Texas at Austin, 2001.
Smooth Convex Approximation to the Maximum Eigenvalue Function (2001)
Xin Chen, Houduo Qi, Liqun Qi, Kok-lay Teo
In this paper, we consider smooth convex approximations to the maximum eigenvalue function. To make it applicable to a wide class of applications, the study is conducted on the composite function of...
Li, Ming, Badger, Jonathan H., Chen, Xin, Kwong, Sam, Kearney, Paul, Zhang, Haoyong
Motivation: Traditional sequence distances require an alignment and therefore are not directly applicable to the problem of whole genome phylogeny where events such as rearrangements make full length...
Typescript.
Advanced oxide thin film fabrication and its application to fuel cells / (2000)
Thesis (Ph. D.)--University of Houston, 2000.
Xin Chen, Houduo Qi, Paul Tseng
For any function f from R to R, one can define a corresponding function on the space of n × n (block-diagonal) real symmetric matrices by applying f to the eigenvalues of the spectral...
Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 1999.
A compression algorithm for DNA sequences and its applications in genome comparison (1999)
We present a lossless compression algorithm, GenCompress, for genetic sequences, based on searching for approximate repeats. Our algorithm achieves the best compression ratios for benchmark DNA...
Non-Interior Continuation Methods For Solving Semidefinite Complementarity Problems (1999)
There recently has been much interest in non-interior continuation/smoothing methods for solving linear/nonlinear complementarity problems. We describe extensions of such methods to complementarity...
Krakauer, Teresa, Chen, Xin, Howard, O. M., Young, Howard A.
Proinflammatory cytokines mediate the toxic effects of superantigenic staphylococcal exotoxins (SE) and bacterial lipopolysaccharide (LPS). Triptolide, an oxygenated diterpene derived from a...
The objective of this thesis is to conduct research on high-precision, continuous GPS monitoring of the crustal deformation in the northern Cascadia subduction zone, which is located in southwestern...
Photocopy of typescript.
Towards an integrated methodology for the development of hybrid information systems. (1998)
Thesis (Ph. D.)--University of Sunderland, 1998.
Strong Duality for a Trust-Region Type Relaxation of the Quadratic Assignment Problem (1998)
Kurt Anstreicher, Xin Chen, Henry Wolkowicz
Lagrangian duality underlies many efficient algorithms for convex minimization problems. A key ingredient is strong duality. Lagrangian relaxation also provides lower bounds for nonconvex problems,...
Strong Duality for a Trust-Region Type Relaxation of QAP (1998)
Kurt Anstreicher, Xin Chen, Henry Wolkowicz, Ya-Xiang Yuan
Lagrangian duality lies behind efficient algorithms for convex minimization problems; in particular, when strong duality holds. It also provides lower bounds for nonconvex problems, where the quality...
Strong Duality for a Trust-Region Type Relaxation of the Quadratic Assignment Problem (1998)
Kurt Anstreicher, Xin Chen, Henry Wolkowicz, Ya-Xiang Yuan
Lagrangian duality underlies many efficient algorithms for convex minimization problems. A key ingredient is strong duality. Lagrangian relaxation also provides lower bounds for nonconvex problems,...
Performance analysis of persistent hypertext transfer protocol (HTTP) over satellite links. (1997)
Thesis (M.S.)--Ohio University, November, 1997.
Thesis (Ph. D.)--Harvard University, 1997.
Performance analysis of persistent hypertext transfer protocol (HTTP) over satellite links (1997)
HTTP/1.0 uses one request/response per TCP connection. Due to the TCP con- nection overhead and the TCP congestion control, this scheme works inefficiently. Persistent HTTP (HTTP/1.1) improves the...
Performance analysis of persistent hypertext transfer protocol (HTTP) over satellite links (1997)
HTTP/1.0 uses one request/response per TCP connection. Due to the TCP con- nection overhead and the TCP congestion control, this scheme works inefficiently. Persistent HTTP (HTTP/1.1) improves the...
Performance Analysis of Persistent HTTP over Satellite Links (1997)
Xin Chen, Shawn D. Ostermann, Warren K. Wray, Fritz J, Fritz J, Dolores H. Russ, ...
iv LIST OF TABLES Table Page 3.1 Web Page Setup . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 3.2 General Performance Comparison for CNN Web Page . . . . . . . . . . 17 3.3...
A Note on Quadratic Forms (1997)
We extend an interesting theorem of Yuan [12] for two quadratic forms to three matrices. Let C 1 ; C 2 ; C 3 be three symmetric matrices in ! n\Thetan , if maxfx T C 1 x; x T C 2 x; x T C 3 xg 0 for...
Thesis (Ph. D.)--University of Hawaii at Manoa, 1996.
Anaytical solution of non-resonant multiphoton Janes-Cumings model with dissipation (1995)
Kuang, L. M., Chen, Xin, Chen, G. H., Ge, M. L.
A new master equation is derived for the Janes-Cummings model.
An alternative approach to Jaynes-Cummings model with dissipation at finite temperature (1995)
Kuang, Le-man, Chen, Guang-hong, Ge, Mo-lin, Chen, Xin
An alternative approach to the Jaynes-Cummings model (JCM) with dissipation at a finite enviromental temperature is presented in terms of a new master equation under Born-Markovian approximations. An...
Thesis (M.S.)--University of Connecticut, 1996.
Synthesis and Allylic Oxidation of 2,3-Dehydro-9β-benzoyloxy-β-agarofuran (1995)
Chen, Xin, Nan, Fajun, Xiong, Zhaoming, Shao, Sichang, Li, Tongshuang, Li, Yulin
2,3-Dehydro-9β-benzoyloxy-β-agarofuran (VI), possible precursor of (+/-)-triptogelin G-2 (I), has been synthesized through a twelve-step procedure, allylic oxidation of which with various oxidative...
A temperature sensitive actin mutation (S14A) in an ATP binding loop of S. cerevisiae actin / (1994)
Typescript (photocopy).
Abstract.
Photocopy of typescript.
Development of an urban roadway management system--[microform] /--by Xin Chen. (1993)
"December 1993."
Modeling and control of a commercial downdraft wood gasifier /--by Xin Chen. (1992)
Thesis (M.S.)--Kansas State University, 1992.
Vita.
Thesis (Ph. D.)--Columbia University, 1990.
Thesis (Ph. D.)--Columbia University, 1990.
Using biased estimates to improve the robot inaccuracy model with ill-conditioned data / (1989)
Thesis (M.S.)--Brigham Young University. Dept. of Statistics.
Object-oriented manipulator design exerciser (OOMANEX) / (1987)
Thesis (M.S.)--University of Maryland, College Park, 1987.
Object-Oriented Manipulator Design Exerciser (OOMANEX). (1987)
The design of-a robotic manipulator system involves complex computations for solving nonlinear, coupled dynamical equations. Our goal to resolve the design difficulties was to have a general program...
Object-Oriented Manipulator Design Exerciser (1987)
Abstract's technical formulas were not compatible with the database used to create this booklet. To obtain a copy, please contact Maggie Virkus at (301) 454-6167, maggie@ra.src.umd.edu or write at to...
Research and Design of Online Declaration and Approval System Based on Mvc (1970)
Wanlin Gao, Hongqiang Yang, Xin Chen, Yang Ping, Zhen Li, Xinlan Jiang, ...
This paper presents a development program of the online declaration and approval system. The system is against the governments functional departments-oriented online community to declaration and...
Crystal structure of ERA: A GTPase-dependent cell cycle regulator containing an RNA binding motif
Chen, Xin, Court, Donald L., Ji, Xinhua
ERA forms a unique family of GTPase. It is widely conserved and essential in bacteria. ERA functions in cell cycle control by coupling cell division with growth rate. ERA homologues also are found in...
Two major forms of DNA (cytosine-5) methyltransferase in human somatic tissues
Hsu, Duen-Wei, Lin, Meng-Jau, Lee, Tai-Lin, Wen, Shau-Ching, Chen, Xin, Shen, C.-K. James
Thus far, only one major form of vertebrate DNA (cytosine-5) methyltransferase (CpG MTase, EC 2.1.1.37) has been identified, cloned, and extensively studied. This enzyme, dnmt1, has been hypothesized...
Gene Expression Patterns in Human Liver Cancers
Chen, Xin, Cheung, Siu Tim, So, Samuel, Fan, Sheung Tat, Barry, Christopher, Higgins, John, ...
Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Using cDNA microarrays to characterize patterns of gene expression in HCC, we found consistent differences between the expression...
Liu, Hong, Kang, Hyeog, Liu, Rui, Chen, Xin, Zhao, Keji
The mammalian SWI/SNF-like chromatin-remodeling BAF complex plays several important roles in controlling cell proliferation and differentiation. Interferons (IFNs) are key mediators of cellular...
High incidence of epithelial cancers in mice deficient for DNA polymerase δ proofreading
Goldsby, Robert E., Hays, Laura E., Chen, Xin, Olmsted, Elise A., Slayton, William B., Spangrude, Gerry J., ...
Mutations are a hallmark of cancer. Normal cells minimize spontaneous mutations through the combined actions of polymerase base selectivity, 3′ → 5′ exonucleolytic proofreading, mismatch...
Leung, Suet Y., Chen, Xin, Chu, Kent M., Yuen, Siu T., Mathy, Jonathan, Ji, Jiafu, ...
We analyzed gene expression patterns in human gastric cancers by using cDNA microarrays representing ≈30,300 genes. Expression of PLA2G2A, a gene previously implicated as a modifier of the ApcMin/+...
Variation in Gene Expression Patterns in Human Gastric Cancers
Chen, Xin, Leung, Suet Y., Yuen, Siu T., Chu, Kent-Man, Ji, Jiafu, Li, Rui, ...
Gastric cancer is the world's second most common cause of cancer death. We analyzed gene expression patterns in 90 primary gastric cancers, 14 metastatic gastric cancers, and 22 nonneoplastic gastric...
Chen, Xin, Yang, Lu, Zhang, Ning, Turpin, Jim A., Buckheit, Robert W., Osterling, Clay, ...
Shikonin is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities, including inhibition of human...
Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors
Sperger, Jamie M., Chen, Xin, Draper, Jonathan S., Antosiewicz, Jessica E., Chon, Chris H., Jones, Sunita B., ...
Remarkably little is known about the transcriptional profiles of human embryonic stem (ES) cells or the molecular mechanisms that underlie their pluripotency. To identify commonalties among the...
The Chromatin-Remodeling BAF Complex Mediates Cellular Antiviral Activities by Promoter Priming
Cui, Kairong, Tailor, Prafullakumar, Liu, Hong, Chen, Xin, Ozato, Keiko, Zhao, Keji
The elicitation of cellular antiviral activities is dependent on the rapid transcriptional activation of interferon (IFN) target genes. It is not clear how the interferon target promoters, which are...
Mutations of PIK3CA in gastric adenocarcinoma
Li, Vivian Sze Wing, Wong, Chi Wai, Chan, Tsun Leung, Chan, Agnes Sze Wah, Zhao, Wei, Chu, Kent-Man, ...
TiProD: the Tissue-specific Promoter Database
Chen, Xin, Wu, Jian-min, Hornischer, Klaus, Kel, Alexander, Wingender, Edgar
TiProD is a database of human promoter sequences for which some functional features are known. It allows a user to query individual promoters and the expression pattern they mediate, gene expression...
CHEN, XIN, MOHR, GEORG, LAMBOWITZ, ALAN M.
The Neurospora crassa mitochondrial tyrosyl-tRNA synthetase (CYT-18 protein) promotes the splicing of group I introns by stabilizing the catalytically active RNA structure. To accomplish this, CYT-18...
Chen, Xin, Yang, Yi-song, Tang, Jian-jun
Naturally occurring plants in agroecosystem evidently play an important role in ecosystem stability. Field studies on the ecological effects of native plants conserved in orchard and their resistance...
Chen, Xin, Zhang, Bing, Fischer, Janice A.
Eukaryotic genomes encode large families of deubiquitinating enzymes (DUBs). Genetic data suggest that Fat facets (Faf), a Drosophila DUB essential for patterning the compound eye, might have a novel...
Chen, Xin, Shevtsov, Sergei P., Hsich, Eileen, Cui, Lei, Haq, Syed, Aronovitz, Mark, ...
In cells capable of entering the cell cycle, including cancer cells, β-catenin has been termed a master switch, driving proliferation over differentiation. However, its role as a transcriptional...
Crystal structure of ERA: A GTPase-dependent cell cycle regulator containing an RNA binding motif
Chen, Xin, Court, Donald L., Ji, Xinhua
ERA forms a unique family of GTPase. It is widely conserved and essential in bacteria. ERA functions in cell cycle control by coupling cell division with growth rate. ERA homologues also are found in...
Two major forms of DNA (cytosine-5) methyltransferase in human somatic tissues
Hsu, Duen-Wei, Lin, Meng-Jau, Lee, Tai-Lin, Wen, Shau-Ching, Chen, Xin, Shen, C.-K. James
Thus far, only one major form of vertebrate DNA (cytosine-5) methyltransferase (CpG MTase, EC 2.1.1.37) has been identified, cloned, and extensively studied. This enzyme, dnmt1, has been hypothesized...
Gene Expression Patterns in Human Liver Cancers
Chen, Xin, Cheung, Siu Tim, So, Samuel, Fan, Sheung Tat, Barry, Christopher, Higgins, John, ...
Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Using cDNA microarrays to characterize patterns of gene expression in HCC, we found consistent differences between the expression...
Liu, Hong, Kang, Hyeog, Liu, Rui, Chen, Xin, Zhao, Keji
The mammalian SWI/SNF-like chromatin-remodeling BAF complex plays several important roles in controlling cell proliferation and differentiation. Interferons (IFNs) are key mediators of cellular...
High incidence of epithelial cancers in mice deficient for DNA polymerase δ proofreading
Goldsby, Robert E., Hays, Laura E., Chen, Xin, Olmsted, Elise A., Slayton, William B., Spangrude, Gerry J., ...
Mutations are a hallmark of cancer. Normal cells minimize spontaneous mutations through the combined actions of polymerase base selectivity, 3′ → 5′ exonucleolytic proofreading, mismatch...
Leung, Suet Y., Chen, Xin, Chu, Kent M., Yuen, Siu T., Mathy, Jonathan, Ji, Jiafu, ...
We analyzed gene expression patterns in human gastric cancers by using cDNA microarrays representing ≈30,300 genes. Expression of PLA2G2A, a gene previously implicated as a modifier of the ApcMin/+...
Chen, Xin, Zhang, Bing, Fischer, Janice A.
Eukaryotic genomes encode large families of deubiquitinating enzymes (DUBs). Genetic data suggest that Fat facets (Faf), a Drosophila DUB essential for patterning the compound eye, might have a novel...
Variation in Gene Expression Patterns in Human Gastric Cancers
Chen, Xin, Leung, Suet Y., Yuen, Siu T., Chu, Kent-Man, Ji, Jiafu, Li, Rui, ...
Gastric cancer is the world's second most common cause of cancer death. We analyzed gene expression patterns in 90 primary gastric cancers, 14 metastatic gastric cancers, and 22 nonneoplastic gastric...
Chen, Xin, Yang, Lu, Zhang, Ning, Turpin, Jim A., Buckheit, Robert W., Osterling, Clay, ...
Shikonin is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities, including inhibition of human...
Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors
Sperger, Jamie M., Chen, Xin, Draper, Jonathan S., Antosiewicz, Jessica E., Chon, Chris H., Jones, Sunita B., ...
Remarkably little is known about the transcriptional profiles of human embryonic stem (ES) cells or the molecular mechanisms that underlie their pluripotency. To identify commonalties among the...
The Chromatin-Remodeling BAF Complex Mediates Cellular Antiviral Activities by Promoter Priming
Cui, Kairong, Tailor, Prafullakumar, Liu, Hong, Chen, Xin, Ozato, Keiko, Zhao, Keji
The elicitation of cellular antiviral activities is dependent on the rapid transcriptional activation of interferon (IFN) target genes. It is not clear how the interferon target promoters, which are...
Mutations of PIK3CA in gastric adenocarcinoma
Li, Vivian Sze Wing, Wong, Chi Wai, Chan, Tsun Leung, Chan, Agnes Sze Wah, Zhao, Wei, Chu, Kent-Man, ...
TiProD: the Tissue-specific Promoter Database
Chen, Xin, Wu, Jian-min, Hornischer, Klaus, Kel, Alexander, Wingender, Edgar
TiProD is a database of human promoter sequences for which some functional features are known. It allows a user to query individual promoters and the expression pattern they mediate, gene expression...
CHEN, XIN, MOHR, GEORG, LAMBOWITZ, ALAN M.
The Neurospora crassa mitochondrial tyrosyl-tRNA synthetase (CYT-18 protein) promotes the splicing of group I introns by stabilizing the catalytically active RNA structure. To accomplish this, CYT-18...
Chen, Xin, Yang, Yi-song, Tang, Jian-jun
Naturally occurring plants in agroecosystem evidently play an important role in ecosystem stability. Field studies on the ecological effects of native plants conserved in orchard and their resistance...
Chen, Xin, Shevtsov, Sergei P., Hsich, Eileen, Cui, Lei, Haq, Syed, Aronovitz, Mark, ...
In cells capable of entering the cell cycle, including cancer cells, β-catenin has been termed a master switch, driving proliferation over differentiation. However, its role as a transcriptional...
Krishnamoorthy, Thanuja, Chen, Xin, Govin, Jerome, Cheung, Wang L., Dorsey, Jean, Schindler, Karen, ...
Sporulation in Saccharomyces cerevisiae is a highly regulated process wherein a diploid cell gives rise to four haploid gametes. In this study we show that histone H4 Ser1 is phosphorylated (H4 S1ph)...
West, Robert B., Corless, Christopher L., Chen, Xin, Rubin, Brian P., Subramanian, Subbaya, Montgomery, Kelli, ...
We recently characterized gene expression patterns in gastrointestinal stromal tumors (GISTs) using cDNA microarrays, and found that the gene FLJ10261 (DOG1, discovered on GIST-1), encoding a...
Gene Expression Patterns in Pancreatic Tumors, Cells and Tissues
Lowe, Anson W., Olsen, Mari, Hao, Ying, Lee, Sum P., Taek Lee, Kyu, Chen, Xin, ...
Chen, Xin, Murakami, Takaya, Oppenheim, Joost J., Howard, O. M. Zack
Triptolide (TPT) is a chemically defined, potent immunosuppressive compound isolated from an anti-inflammatory Chinese herbal medicine. TPT has been reported to inhibit autoimmunity, allograft...
Howard, O. M. Zack, Dong, Hui Fang, Su, Shao Bo, Caspi, Rachel R., Chen, Xin, Plotz, Paul, ...
We tested the hypothesis that interaction between autoantigens and chemoattractant receptors may be an important step in the development of autoimmunity. The retinal autoantigens S-antigen (S-Ag) and...
Subcellular Transport of EKLF and Switch-On of Murine Adult βmaj Globin Gene Transcription▿
Shyu, Yu-Chiau, Lee, Tung-Liang, Wen, Shau-Ching, Chen, Hsin, Hsiao, Wei-Yuan, Chen, Xin, ...
Erythroid Krüppel-like factor (EKLF) is an essential transcription factor for mammalian β-like globin gene switching, and it specifically activates transcription of the adult β globin gene through...
Sääf, Annika M., Halbleib, Jennifer M., Chen, Xin, Yuen, Siu Tsan, Leung, Suet Yi, Nelson, W. James, ...
Posttranslational mechanisms are implicated in the development of epithelial cell polarity, but little is known about the patterns of gene expression and transcriptional regulation during this...
PlantTFDB: a comprehensive plant transcription factor database
Guo, An-Yuan, Chen, Xin, Gao, Ge, Zhang, He, Zhu, Qi-Hui, Liu, Xiao-Chuan, ...
Transcription factors (TFs) play key roles in controlling gene expression. Systematic identification and annotation of TFs, followed by construction of TF databases may serve as useful resources for...
Curcumin prevents and reverses murine cardiac hypertrophy
Li, Hong-Liang, Liu, Chen, De Couto, Geoffrey, Ouzounian, Maral, Sun, Mei, Wang, Ai-Bing, ...
Chromatin remodeling, particularly histone acetylation, plays a critical role in the progression of pathological cardiac hypertrophy and heart failure. We hypothesized that curcumin, a natural...
Distinct pathways of genomic progression to benign and malignant tumors of the liver
Tward, Aaron D., Jones, Kirk D., Yant, Stephen, Cheung, Siu Tim, Fan, Sheung Tat, Chen, Xin, ...
We used several of the genetic lesions commonly associated with human liver tumors to reconstruct genetic progression to hepatocellular carcinoma and adenoma in mouse models. We initiated...
Kosinski, Cynthia, Li, Vivian S. W., Chan, Annie S. Y., Zhang, Ji, Ho, Coral, Tsui, Wai Yin, ...
Human colonic epithelial cell renewal, proliferation, and differentiation are stringently controlled by numerous regulatory pathways. To identify genetic programs of human colonic epithelial cell...
Activation of Interleukin-32 Pro-Inflammatory Pathway in Response to Influenza A Virus Infection
Li, Wei, Liu, Yan, Mukhtar, Muhammad Mahmood, Gong, Rui, Pan, Ying, Rasool, Sahibzada T., ...
Cunningham, Malcolm A., Rondeau, Eric, Chen, Xin, Coughlin, Shaun R., Holdsworth, Stephen R., Tipping, Peter G.
Protease-activated receptor (PAR)-1 is a cellular receptor for thrombin that is activated after proteolytic cleavage. The contribution of PAR-1 to inflammatory cell–mediated renal injury was...
Splenic CD19−CD35+B220+ cells function as an inducer of follicular dendritic cell network formation
Murakami, Takaya, Chen, Xin, Hase, Koji, Sakamoto, Ayako, Nishigaki, Chie, Ohno, Hiroshi
Follicular dendritic cells (FDCs) form a reticular FDC network in the lymphoid follicle that is essential for the retention and presentation of native antigens in the form of antigen-antibody immune...
EFFECTS OF ANNEALING AND Ar INTERCALATION ON GLASS TRANSITION IN C60 FILMS
JIAN WU, MIN GU, LILI ZHANG, YAO YU, XIN CHEN, TONG B. TANG
C60 films were fabricated by vacuum sublimation and studied with dielectric spectroscopy regarding glass transition. With annealing, the dielectric loss peaks decreased in height, and the apparent...
Policy burdens, firm performance, and management turnover
Liao, Guanmin, Chen, Xin, Jing, Xin, Sun, Jianfei
Lin, Cai, and Li [Lin, Y., Cai, F., Li, Z., 1998. Competition, policy burdens, and state-owned enterprise reform. American Economic Review 88, 422-327] argue that under information asymmetry, SOE...
Curcumin prevents and reverses murine cardiac hypertrophy
Li, Hong-Liang, Liu, Chen, De Couto, Geoffrey, Ouzounian, Maral, Sun, Mei, Wang, Ai-Bing, ...
Li, Yan, Peng, Quan, Selimi, Dija, Wang, Qi, Charkowski, Amy O., Chen, Xin, ...
The type III secretion system (T3SS) is a major virulence factor in many gram-negative bacterial pathogens. This secretion system translocates effectors directly into the cytosol of eukaryotic host...
Development of regulatory T cells requires IL-7Rα stimulation by IL-7 or TSLP
Mazzucchelli, Renata, Hixon, Julie A., Spolski, Rosanne, Chen, Xin, Li, Wen Qing, Hall, Veronica L., ...
Interleukin-7 (IL-7), a cytokine produced by stromal cells, is required for thymic development and peripheral homeostasis of most major subsets of T cells. We examined whether regulatory T (Treg)...
Weiss, Jonathan M., Back, Timothy C., Scarzello, Anthony J., Subleski, Jeff J., Hall, Veronica L., Stauffer, Jimmy K., ...
Treatment of mice bearing orthotopic, metastatic tumors with anti-CD40 antibody resulted in only partial, transient anti-tumor effects whereas combined treatment with IL-2/anti-CD40, induced tumor...