Bao-zhu Yang, Henry R. Kranzler, Hongyu Zhao, Jeffrey R. Gruen, Xingguang Luo, Joel Gelernter
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Luo, Xingguang, Zuo, Lingjun, Kranzler, Henry R, Wang, Shuang, Anton, Raymond F, Gelernter, Joel
Abstract Background In our previous studies, we reported positive associations between seven ADH4 polymorphisms and substance dependence [i.e., alcohol dependence (AD) and/or drug dependence (DD)] in...
Yang, Bao-Zhu, Kranzler, Henry R., Zhao, Hongyu, Gruen, Jeffrey R., Luo, Xingguang, Gelernter, Joel
There have been many conflicting reports concerning the association of the DRD2 locus with alcohol dependence (AD). To investigate whether these findings could be reconciled by considering the...
CHRM2 variation predisposes to personality traits of agreeableness and conscientiousness (2007)
Luo, Xingguang, Kranzler, Henry R., Zuo, Lingjun, Zhang, Huiping, Wang, Shuang, Gelernter, Joel
Personality traits are among the most complex quantitative traits. Certain personality traits have been postulated to be part of the inherited component of substance dependence (SD) risk. Association...
Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans (2007)
Luo, Xingguang, Kranzler, Henry R., Zuo, Lingjun, Wang, Shuang, Schork, Nicholas J., Gelernter, Joel
Drug dependence (DD) is commonly co-morbid with alcohol dependence (AD). Many studies have also shown common genetic risk factors for these disorders. We previously reported associations of AD with...
Variation at APOE and STH loci and Alzheimer's disease. (2006)
Zuo, Lingjun, Van Dyck, Christopher, Luo, Xingguang, Kranzler, Henry, Yang, Bao-Zhu, Gelernter, Joel
ABSTRACT: BACKGROUND: The apolipoprotein E (APOE) and tau proteins play important roles in the pathological development of Alzheimer's disease (AD). Many studies have shown an association between the...
Variation at APOEand STHloci and Alzheimer's disease (2006)
Zuo, Lingjun, Van Dyck, Christopher H, Luo, Xingguang, Kranzler, Henry R, Yang, Bao-zhu, Gelernter, Joel
Abstract Background The apolipoprotein E (APOE) and tau proteins play important roles in the pathological development of Alzheimer's disease (AD). Many studies have shown an association between the...
Zhang, Huiping, Luo, Xingguang, Kranzler, Henry R., Lappalainen, Jaakko, Yang, Bao-Zhu, Krupitsky, Evgeny, ...
We examined 13 single nucleotide polymorphisms (SNPs) spanning the coding region of the µ-opioid receptor gene (OPRM1), among 382 European Americans (EAs) affected with substance dependence [alcohol...
Zhang, Huiping, Luo, Xingguang, Kranzler, Henry R., Lappalainen, Jaakko, Yang, Bao-Zhu, Krupitsky, Evgeny, ...
We examined 13 single nucleotide polymorphisms (SNPs) spanning the coding region of the µ-opioid receptor gene (OPRM1), among 382 European Americans (EAs) affected with substance dependence [alcohol...
Multiple ADH genes modulate risk for drug dependence (2006)
Luo, Xingguang, Kranzler, Henry R., Zuo, Lingjun, Wang, Shuang, Schork, Nicholas J., Gelernter, Joel
Drug dependence (DD) is commonly co-morbid with alcohol dependence (AD). Many studies have also shown common genetic risk factors for these disorders. We previously reported associations of AD with...
Luo, Xingguang, Kranzler, Henry R., Zuo, Lingjun, Wang, Shuang, Blumberg, Hilary P., Gelernter, Joel
Cholinergic muscarinic 2 receptor (CHRM2) is implicated in memory and cognition, functions impaired in many neuropsychiatric disorders. Wang et al. (2004) reported that variation in CHRM2 gene...
Luo, Xingguang, Kranzler, Henry R., Zuo, Lingjun, Wang, Shuang, Blumberg, Hilary P., Gelernter, Joel
Cholinergic muscarinic 2 receptor (CHRM2) is implicated in memory and cognition, functions impaired in many neuropsychiatric disorders. Wang et al. [Wang, J.C., Hinrichs, A.L., Stock, H., Budde, J.,...
Variation at APOE and STH loci and Alzheimer's disease
Zuo, Lingjun, Van Dyck, Christopher H, Luo, Xingguang, Kranzler, Henry R, Yang, Bao-zhu, Gelernter, Joel
Luo, Xingguang, Kranzler, Henry R., Zuo, Lingjun, Wang, Shuang, Schork, Nicholas J., Gelernter, Joel
The set of alcohol-metabolizing enzymes has considerable genetic and functional complexity. The relationships between some alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) genes and...
Luo, Xingguang, Kranzler, Henry R., Zuo, Lingjun, Wang, Shuang, Schork, Nicholas J., Gelernter, Joel
The set of alcohol-metabolizing enzymes has considerable genetic and functional complexity. The relationships between some alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) genes and...
Variation at APOE and STH loci and Alzheimer's disease
Zuo, Lingjun, Van Dyck, Christopher H, Luo, Xingguang, Kranzler, Henry R, Yang, Bao-zhu, Gelernter, Joel