Impaired Balance of Mitochondria Fission and Fusion in Alzheimer Disease (2009)
Alzheimer's disease (AD) is the leading cause of dementia in the elderly, characterized by neurofibrillary tangles, senile plaques and a progressive loss of neuronal cells in selective brain regions....
Impaired Balance of Mitochondria Fission and Fusion in Alzheimer Disease (2009)
Alzheimer's disease (AD) is the leading cause of dementia in the elderly, characterized by neurofibrillary tangles, senile plaques and a progressive loss of neuronal cells in selective brain regions....
Su, Bo, Liu, Haihua, Wang, Xinglong, Chen, Shu G, Siedlak, Sandra L, Kondo, Eisaku, ...
ABSTRACT: Lewy bodies and Lewy neurites constitute the cardinal neuropathological features of both Parkinson's disease (PD) and Lewy body dementia (LBD). Whereas alpha-synuclein has been found to be...
Distinguishing the species of biomedical named entities for term identification (2008)
Wang, Xinglong, Matthews, Michael
Abstract Background Term identification is the task of grounding ambiguous mentions of biomedical named entities in text to unique database identifiers. Previous work on term identification has...
Automating curation using a natural language processing pipeline (2008)
Alex, Beatrice, Grover, Claire, Haddow, Barry, Kabadjov, Mijail, Klein, Ewan, Matthews, Michael, ...
Abstract Background: The tasks in BioCreative II were designed to approximate some of the laborious work involved in curating biomedical research papers. The approach to these tasks taken by the...
Introducing meta-services for biomedical information extraction (2008)
Leitner, Florian, Krallinger, Martin, Rodriguez-Penagos, Carlos, Hakenberg, Jörg, Plake, Conrad, Kuo, Cheng-Ju, ...
Abstract We introduce the first meta-service for information extraction in molecular biology, the BioCreative MetaServer (BCMS; http://bcms.bioinfo.cnio.es/ ). This prototype platform is a joint...
Overview of BioCreative II gene normalization (2008)
Morgan, Alexander A, Lu, Zhiyong, Wang, Xinglong, Cohen, Aaron M, Fluck, Juliane, Ruch, Patrick, ...
Abstract Background: The goal of the gene normalization task is to link genes or gene products mentioned in the literature to biological databases. This is a key step in an accurate search of the...
Introducing meta-services for biomedical information extraction (2008)
Leitner, Florian, Krallinger, Martin, Rodriguez-Penagos, Carlos, Hakenberg, Jorg, Plake, Conrad, Kuo, Cheng-Ju, ...
We introduce the first meta-service for information extraction in molecular biology, the BioCreative MetaServer (BCMS; http://bcms.bioinfo.cnio.es/). This prototype platform is a joint effort of 13...
We present a novel almost-unsupervised approach to the task of Word Sense Disambiguation (WSD). We build sense examples automatically, using large quantities of Chinese text, and English-Chinese and...
T6 System Description 1 Adapting a Relation Extraction Pipeline for the BioCreAtIvE II Tasks (2008)
Claire Grover, Barry Haddow, Ewan Klein, Michael Matthews, Leif Arda Neilsen, Richard Tobin, ...
The Second BioCreAtIvE Challenge provided an ideal opportunity to evaluate biomedical nlp techniques. Prior to the Challenge, an information extraction pipeline was developed to extract entities and...
We present a novel almost-unsupervised approach to the task of Word Sense Disambiguation (WSD). We build sense examples automatically, using large quantities of Chinese text, and English-Chinese and...
Wang, Xinglong, Su, Bo, Fujioka, Hisashi, Zhu, Xiongwei
Mitochondrial function relies heavily on its morphology and distribution, alterations of which have been increasingly implicated in neurodegenerative diseases, such as Alzheimer's disease (AD). In...
Assisted curation: does text mining really help (2008)
Beatrice Alex, Claire Grover, Barry Haddow, Mijail Kabadjov, Ewan Klein, Xinglong Wang
Although text mining shows considerable promise as a tool for supporting the curation of biomedical text, there is little concrete evidence as to its effectiveness. We report on three experiments...
Comparing usability of matching techniques for normalising biomedical named entities (2008)
Xinglong Wang, Michael Matthews
String matching plays an important role in biomedical Term Normalisation, the task of linking mentions of biomedical entities to identifiers in reference databases. This paper evaluates exact,...
Wang, Xinglong, Su, Bo, Siedlak, Sandra L., Moreira, Paula I., Fujioka, Hisashi, Wang, Yang, ...
Mitochondrial dysfunction is a prominent feature of Alzheimer disease but the underlying mechanism is unclear. In this study, we investigated the effect of amyloid precursor protein (APP) and amyloid...
Rule-based protein term identification with help from automatic species tagging (2007)
Abstract. In biomedical articles, terms often refer to different protein entities. For example, an arbitrary occurrence of term p53 might denote thousands of proteins across a number of species. A...
Word Relatives in Context for Word Sense Disambiguation (2006)
Martinez, David, Agirre, Eneko, Wang, Xinglong
The current situation for Word Sense Disambiguation (WSD) is somewhat stuck due to lack of training data. We present in this paper a novel disambiguation algorithm that improves previous systems...
Word Relatives in Context for Word Sense Disambiguation (2006)
Martinez, David, Agirre, Eneko, Wang, Xinglong
The current situation for Word Sense Disambiguation (WSD) is somewhat stuck due to lack of training data. We present in this paper a novel disambiguation algorithm that improves previous systems...
Word Relatives in Context for Word Sense Disambiguation (2006)
Martinez, David, Agirre, Eneko, Wang, Xinglong
The current situation for Word Sense Disambiguation (WSD) is somewhat stuck due to lack of training data. We present in this paper a novel disambiguation algorithm that improves previous systems...
Dongli Zhao, Qian Wang, Guoyin Kai, Xinglong Wang, Juan Lin, Yan Pi, ...
By RACE-PCR cloning, a cDNA encoding taxane 2α-O-benzoyltransferase (designated as TmTBT) was isolated from Taxus media, which catalyzes the conversion of 2-debenzoyl-7,13-diacetylbaccatin III,...
Word Relatives in Context for Word Sense Disambiguation (2006)
Martinez, David, Agirre, Eneko, Wang, Xinglong
The current situation for Word Sense Disambiguation (WSD) is somewhat stuck due to lack of training data. We present in this paper a novel disambiguation algorithm that improves previous systems...
Word Relatives in Context for Word Sense Disambiguation (2006)
Martinez, David, Agirre, Eneko, Wang, Xinglong
The current situation for Word Sense Disambiguation (WSD) is somewhat stuck due to lack of training data. We present in this paper a novel disambiguation algorithm that improves previous systems...
Word Relatives in Context for Word Sense Disambiguation (2006)
Martinez, David, Agirre, Eneko, Wang, Xinglong
The current situation for Word Sense Disambiguation (WSD) is somewhat stuck due to lack of training data. We present in this paper a novel disambiguation algorithm that improves previous systems...
Dongli Zhao, Qian Wang, Guoyin Kai, Xinglong Wang, Juan Lin, Yan Pi, ...
By RACE-PCR cloning, a cDNA encoding taxane 2α-O-benzoyltransferase (designated as TmTBT) was isolated from Taxus media, which catalyzes the conversion of 2-debenzoyl-7,13-diacetylbaccatin...
Word Relatives in Context for Word Sense Disambiguation (2006)
Martinez, David, Agirre, Eneko, Wang, Xinglong
The current situation for Word Sense Disambiguation (WSD) is somewhat stuck due to lack of training data. We present in this paper a novel disambiguation algorithm that improves previous systems...
Word sense disambiguation using automatically translated sense examples (2006)
We present an unsupervised approach to Word Sense Disambiguation (WSD). We automatically acquire English sense examples using an English-Chinese bilingual dictionary, Chinese monolingual corpora and...
Word Relatives in Context for Word Sense Disambiguation (2006)
Martinez, David, Agirre, Eneko, Wang, Xinglong
The current situation for Word Sense Disambiguation (WSD) is somewhat stuck due to lack of training data. We present in this paper a novel disambiguation algorithm that improves previous systems...
Word Relatives in Context for Word Sense Disambiguation (2006)
Martinez, David, Agirre, Eneko, Wang, Xinglong
The current situation for Word Sense Disambiguation (WSD) is somewhat stuck due to lack of training data. We present in this paper a novel disambiguation algorithm that improves previous systems...
Göttingen, Universität, Thesis (doctoral), 2002.
Automating curation using a natural language processing pipeline
Alex, Beatrice, Grover, Claire, Haddow, Barry, Kabadjov, Mijail, Klein, Ewan, Matthews, Michael, ...
Overview of BioCreative II gene normalization
Morgan, Alexander A, Lu, Zhiyong, Wang, Xinglong, Cohen, Aaron M, Fluck, Juliane, Ruch, Patrick, ...
Introducing meta-services for biomedical information extraction
Leitner, Florian, Krallinger, Martin, Rodriguez-Penagos, Carlos, Hakenberg, Jörg, Plake, Conrad, Kuo, Cheng-Ju, ...
We introduce the first meta-service for information extraction in molecular biology, the BioCreative MetaServer (BCMS; ). This prototype platform is a joint effort of 13 research groups and provides...
Wang, Xinglong, Su, Bo, Fujioka, Hisashi, Zhu, Xiongwei
Mitochondrial function relies heavily on its morphology and distribution, alterations of which have been increasingly implicated in neurodegenerative diseases, such as Alzheimer’s disease (AD). In...
Wang, Xinglong, Su, Bo, Siedlak, Sandra L., Moreira, Paula I., Fujioka, Hisashi, Wang, Yang, ...
Mitochondrial dysfunction is a prominent feature of Alzheimer disease but the underlying mechanism is unclear. In this study, we investigated the effect of amyloid precursor protein (APP) and amyloid...
Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease
Su, Bo, Liu, Haihua, Wang, Xinglong, Chen, Shu G, Siedlak, Sandra L, Kondo, Eisaku, ...
Lewy bodies and Lewy neurites constitute the cardinal neuropathological features of both Parkinson's disease (PD) and Lewy body dementia (LBD). Whereas α-synuclein has been found to be the major...