Xinwei She

Definition, conservation and epigenetics of housekeeping and tissue-enriched genes (2009)

She, Xinwei, Rohl, Carol A, Castle, John C, Kulkarni, Amit V, Johnson, Jason M, Chen, Ronghua

Abstract Background Housekeeping genes (HKG) are constitutively expressed in all tissues while tissue-enriched genes (TEG) are expressed at a much higher level in a single tissue type than in others....

The genomic distribution of intraspecific and interspecific sequence divergence of human segmental duplications relative to human/chimpanzee chromosomal rearrangements (2008)

Marques-Bonet, Tomàs, Cheng, Ze, She, Xinwei, Eichler, Evan E, Navarro, Arcadi

Abstract Background It has been suggested that chromosomal rearrangements harbor the molecular footprint of the biological phenomena which they induce, in the form, for instance, of changes in the...

Islands of euchromatin-like sequence and expressed polymorphic sequences within the short arm of human chromosome 21 (2007)

Lyle, Robert, Prandini, Paola, Osoegawa, Kazutoyo, Ten Hallers, Boudewijn, Humphray, Sean, Zhu, Baoli, ...

The goals of the human genome project did not include sequencing of the heterochromatic regions. We describe here an initial sequence of 1.1 Mb of the short arm of human chromosome 21 (HSA21p),...

Independent centromere formation in a capricious, gene-free domain of chromosome 13q21 in Old World monkeys and pigs (2006)

Cardone, Maria, Alonso, Alicia, Pazienza, Michele, Ventura, Mario, Montemurro, Gabriella, Carbone, Lucia, ...

Abstract Background Evolutionary centromere repositioning and human analphoid neocentromeres occurring in clinical cases are, very likely, two stages of the same phenomenon whose properties still...

A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications. (2006)

She, Xinwei, Liu, Ge, Ventura, Mario, Zhao, Shaying, Misceo, Doriana, Roberto, Roberta, ...

Compared with other sequenced animal genomes, human segmental duplications appear larger, more interspersed, and disproportionately represented as high-sequence identity alignments. Global sequence...

A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications (2006)

She, Xinwei, Liu, Ge, Ventura, Mario, Zhao, Shaying, Misceo, Doriana, Roberto, Roberta, ...

Compared with other sequenced animal genomes, human segmental duplications appear larger, more interspersed, and disproportionately represented as high-sequence identity alignments. Global sequence...

A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications (2006)

She, Xinwei, Liu, Ge, Ventura, Mario, Zhao, Shaying, Misceo, Doriana, Roberto, Roberta, ...

Compared with other sequenced animal genomes, human segmental duplications appear larger, more interspersed, and disproportionately represented as high-sequence identity alignments. Global sequence...

The sequence and analysis of duplication rich human chromosome 16 (2004)

Martin, Joel, Han, Cliff, Gordon, Laurie A., Terry, Astrid, Prabhakar, Shyam, She, Xinwei, ...

We report here the 78,884,754 base pairs of finished human chromosome 16 sequence, representing over 99.9 percent of its euchromatin. Manual annotation revealed 880 protein coding genes confirmed by...

The complete sequence of human chromosome 5 (2004)

Schmutz, Jeremy, Martin, Joel, Terry, Astrid, Couronne, Olivier, Grimwood, Jane, Lowry, State, ...

Chromosome 5 is one of the largest human chromosomes yet has one of the lowest gene densities. This is partially explained by numerous gene-poor regions that display a remarkable degree of noncoding...

Recurrent sites for new centromere seeding. (2004)

Ventura, Mario, Weigl, Stefania, Carbone, Lucia, Cardone, Maria Francesca, Misceo, Doriana, Teti, Mariagrazia, ...

Using comparative FISH and genomics, we have studied and compared the evolution of chromosome 3 in primates and two human neocentromere cases on the long arm of this chromosome. Our results show that...

Regional patterns of gene expression in human and chimpanzee brains. (2004)

Khaitovich, Philipp, Muetzel, Bjoern, She, Xinwei, Lachmann, Michael, Hellmann, Ines, Dietzsch, Janko, ...

We have analyzed gene expression in various brain regions of humans and chimpanzees. Within both human and chimpanzee individuals, the transcriptomes of the cerebral cortex are very similar to each...

Regional Patterns of Gene Expression in Human and Chimpanzee Brains (2004)

Khaitovich, Philipp, Muetzel, Bjoern, She, Xinwei, Lachmann, Michael, Hellmann, Ines, Dietzsch, Janko, ...

We have analyzed gene expression in various brain regions of humans and chimpanzees. Within both human and chimpanzee individuals, the transcriptomes of the cerebral cortex are very similar to each...

Regional Patterns of Gene Expression in Human and Chimpanzee Brains

Khaitovich, Philipp, Muetzel, Bjoern, She, Xinwei, Lachmann, Michael, Hellmann, Ines, Dietzsch, Janko, ...

We have analyzed gene expression in various brain regions of humans and chimpanzees. Within both human and chimpanzee individuals, the transcriptomes of the cerebral cortex are very similar to each...

Recurrent Sites for New Centromere Seeding

Ventura, Mario, Weigl, Stefania, Carbone, Lucia, Cardone, Maria Francesca, Misceo, Doriana, Teti, Mariagrazia, ...

Using comparative FISH and genomics, we have studied and compared the evolution of chromosome 3 in primates and two human neocentromere cases on the long arm of this chromosome. Our results show that...

A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications

She, Xinwei, Liu, Ge, Ventura, Mario, Zhao, Shaying, Misceo, Doriana, Roberto, Roberta, ...

Compared with other sequenced animal genomes, human segmental duplications appear larger, more interspersed, and disproportionately represented as high-sequence identity alignments. Global sequence...

Regional Patterns of Gene Expression in Human and Chimpanzee Brains

Khaitovich, Philipp, Muetzel, Bjoern, She, Xinwei, Lachmann, Michael, Hellmann, Ines, Dietzsch, Janko, ...

We have analyzed gene expression in various brain regions of humans and chimpanzees. Within both human and chimpanzee individuals, the transcriptomes of the cerebral cortex are very similar to each...

Recurrent Sites for New Centromere Seeding

Ventura, Mario, Weigl, Stefania, Carbone, Lucia, Cardone, Maria Francesca, Misceo, Doriana, Teti, Mariagrazia, ...

Using comparative FISH and genomics, we have studied and compared the evolution of chromosome 3 in primates and two human neocentromere cases on the long arm of this chromosome. Our results show that...

A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications

She, Xinwei, Liu, Ge, Ventura, Mario, Zhao, Shaying, Misceo, Doriana, Roberto, Roberta, ...

Compared with other sequenced animal genomes, human segmental duplications appear larger, more interspersed, and disproportionately represented as high-sequence identity alignments. Global sequence...

Independent centromere formation in a capricious, gene-free domain of chromosome 13q21 in Old World monkeys and pigs

Cardone, Maria Francesca, Alonso, Alicia, Pazienza, Michele, Ventura, Mario, Montemurro, Gabriella, Carbone, Lucia, ...

The mammalian evolutionary history of chromosome 13 was characterized and evolutionary-new centromeres compared to two human neocentromeres at 13q21 using chromatin immunoprecipitation and genomic...

Islands of euchromatin-like sequence and expressed polymorphic sequences within the short arm of human chromosome 21

Lyle, Robert, Prandini, Paola, Osoegawa, Kazutoyo, Ten Hallers, Boudewijn, Humphray, Sean, Zhu, Baoli, ...

The goals of the human genome project did not include sequencing of the heterochromatic regions. We describe here an initial sequence of 1.1 Mb of the short arm of human chromosome 21 (HSA21p),...