Myxoma Virus M11L Prevents Apoptosis through Constitutive Interaction with Bak
Wang, Gen, Barrett, John W., Nazarian, Steven H., Everett, Helen, Gao, Xiujuan, Bleackley, Chris, ...
M11L, a 166-amino-acid antiapoptotic protein of myxoma virus, was previously shown to bind to the peripheral benzodiazepine receptor by hydrophobic interactions at the outer mitochondrial membrane....
Su, Jin, Wang, Gen, Barrett, John W., Irvine, Timothy S., Gao, Xiujuan, McFadden, Grant
Many viruses inhibit or retard apoptosis, a strategy that subverts one of the most ancient antiviral mechanisms. M11L, a myxoma virus-encoded antiapoptotic protein, has been previously shown to...
Wang, Gen, Barrett, John W., Stanford, Marianne, Werden, Steven J., Johnston, James B., Gao, Xiujuan, ...
We demonstrate that the susceptibility of human cancer cells to be infected and killed by an oncolytic poxvirus, myxoma virus (MV), is related to the basal level of endogenous phosphorylated Akt. We...
Myxoma Virus M11L Prevents Apoptosis through Constitutive Interaction with Bak
Wang, Gen, Barrett, John W., Nazarian, Steven H., Everett, Helen, Gao, Xiujuan, Bleackley, Chris, ...
M11L, a 166-amino-acid antiapoptotic protein of myxoma virus, was previously shown to bind to the peripheral benzodiazepine receptor by hydrophobic interactions at the outer mitochondrial membrane....
Su, Jin, Wang, Gen, Barrett, John W., Irvine, Timothy S., Gao, Xiujuan, McFadden, Grant
Many viruses inhibit or retard apoptosis, a strategy that subverts one of the most ancient antiviral mechanisms. M11L, a myxoma virus-encoded antiapoptotic protein, has been previously shown to...
Wang, Gen, Barrett, John W., Stanford, Marianne, Werden, Steven J., Johnston, James B., Gao, Xiujuan, ...
We demonstrate that the susceptibility of human cancer cells to be infected and killed by an oncolytic poxvirus, myxoma virus (MV), is related to the basal level of endogenous phosphorylated Akt. We...
M135R Is a Novel Cell Surface Virulence Factor of Myxoma Virus▿
Barrett, John W., Sypula, Joanna, Wang, Fuan, Alston, Lindsay R., Shao, Zhuhong, Gao, Xiujuan, ...
Myxoma virus (MV) encodes a cell surface protein (M135R) that is predicted to mimic the host alpha/beta interferon receptor (IFN-α/β-R) and thus prevent IFN-α/β from triggering a host antiviral...
Wang, Fuan, Gao, Xiujuan, Barrett, John W., Shao, Qing, Bartee, Eric, Mohamed, Mohamed R., ...
The sensing of pathogen infection and subsequent triggering of innate immunity are key to controlling zoonotic infections. Myxoma virus (MV) is a cytoplasmic DNA poxvirus that in nature infects only...