Xu-guang Zhu

Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein (2008)

Liaw, Wen-Jinn, Zhu, Xu-Guang, Yaster, Myron, Johns, Roger A, Gauda, Estelle B, Tao, Yuan-Xiang

Abstract Postsynaptic density (PSD)-93, a neuronal scaffolding protein, binds to and clusters N -methyl-D-aspartate receptor (NMDAR) subunits NR2A and NR2B at cellular membranes in vitro . However,...

Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms (2007)

Hishimoto, Akitoyo, Liu, Qing-Rong, Drgon, Tomas, Pletnikova, Olga, Walther, Donna, Zhu, Xu-Guang, ...

Neurexins are cell adhesion molecules that help to specify and stabilize synapses and provide receptors for neuroligins, neurexophilins, dystroglycans and α-latrotoxins. We previously reported...

Mice with a targeted mutation in the thyroid hormone β receptor gene exhibit impaired growth and resistance to thyroid hormone

Kaneshige, Masahiro, Kaneshige, Kumiko, Zhu, Xu-guang, Dace, Alexandra, Garrett, Lisa, Carter, Todd A., ...

Patients with mutations in the thyroid hormone receptor β (TRβ) gene manifest resistance to thyroid hormone (RTH), resulting in a constellation of variable phenotypic abnormalities. To understand...

The Orphan Nuclear Receptor Ear-2 Is a Negative Coregulator for Thyroid Hormone Nuclear Receptor Function

Zhu, Xu-guang, Park, Kyung Soo, Kaneshige, Masahiro, Bhat, Manoj K., Zhu, Qihong, Mariash, Cary N., ...

Thyroid hormone (T3) nuclear receptors (TR) are ligand-dependent transcription factors which regulate growth, differentiation, and development. One emerging hypothesis suggests that TR mediate these...

Mice with a targeted mutation in the thyroid hormone β receptor gene exhibit impaired growth and resistance to thyroid hormone

Kaneshige, Masahiro, Kaneshige, Kumiko, Zhu, Xu-guang, Dace, Alexandra, Garrett, Lisa, Carter, Todd A., ...

Patients with mutations in the thyroid hormone receptor β (TRβ) gene manifest resistance to thyroid hormone (RTH), resulting in a constellation of variable phenotypic abnormalities. To understand...

The Orphan Nuclear Receptor Ear-2 Is a Negative Coregulator for Thyroid Hormone Nuclear Receptor Function

Zhu, Xu-guang, Park, Kyung Soo, Kaneshige, Masahiro, Bhat, Manoj K., Zhu, Qihong, Mariash, Cary N., ...

Thyroid hormone (T3) nuclear receptors (TR) are ligand-dependent transcription factors which regulate growth, differentiation, and development. One emerging hypothesis suggests that TR mediate these...

Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein

Liaw, Wen-Jinn, Zhu, Xu-Guang, Yaster, Myron, Johns, Roger A, Gauda, Estelle B, Tao, Yuan-Xiang

Postsynaptic density (PSD)-93, a neuronal scaffolding protein, binds to and clusters N-methyl-D-aspartate receptor (NMDAR) subunits NR2A and NR2B at cellular membranes in vitro. However, the roles of...