Avian Metapneumovirus Subtype A in China and Subtypes A and B in Nigeria (2008)
A.A. Owoade, M.F. Ducatez, J.M. Hübschen, A. Sausy, H. Chen, Y. Guan, ...
Avian Metapneumovirus Subtype A in China and Subtypes A and B in Nigeria (2008)
A.A. Owoade, M.F. Ducatez, J.M. Hübschen, A. Sausy, H. Chen, Y. Guan, ...
In order to detect and characterize avian metapneumovirus, organs or swabs were collected from 697 chicken and 110 turkeys from commercial farms in Southwestern Nigeria and from 107 chickens from...
Aquino, Wilkins, Connelly, Robert, Earls, Christopher J., Ewert, Eduard, Guan, Y., Guggenberger, Werner, ...
IASS-IACM 2008 Session: Structural Stability -- Session Organizer: Herbert MANG (Technical University of Vienna) -- Plenary Lecture: Abstract, Slides and Video: "Answers to three not quite...
M.F. Ducatez, H. Chen, Y. Guan, C.P. Muller
Between January 2004 and December 2005, cloacal swabs from essentially healthy chickens and silky chickens from live birds markets in Guangdong and Hunan provinces in southeastern China were screened...
A model to control the epidemic of H5N1 influenza at the source (2007)
Guan, Y, Chen, H, Li, KS, Riley, S, Leung, GM, Webster, R, ...
Abstract Background No country is fully prepared for a 1918-like pandemic influenza. Averting a pandemic of H5N1 influenza virus depends on the successful control of its endemicity, outbreaks in...
Changing Epidemiology and Ecology of Highly Pathogenic Avian H5N1 Influenza Viruses (2007)
R. G. Webster, Y. Guan, M. Peiris, G. Smith, ...
CHANGING EPIDEMIOLOGY AND ECOLOGY OF HIGHLY PATHOGENIC AVIAN H5N1 INFLUENZA VIRUSES (2007)
R.G. Webster, Y. Guan, M. Peiris, G. Smith, ...
HCLP Based Service Composition (2006)
A key impediment to the widespread adoption of web services is the relatively limited set of tools available to deal with Quality-of-Service (QoS) factors. QoS factors pose several difficult...
HCLP Based Service Composition (2006)
A key impediment to the widespread adoption of web services is the relatively limited set of tools available to deal with Quality-of-Service (QoS) factors. QoS factors pose several difficult...
Co-evolution of i* Models and 3APL Agents (2006)
Krishna, A., Guan, Y., Ghose, A.
Agent-Oriented Conceptual Modelling (AOCM), as exemplified by the i* notation [9], represents an interesting approach to modelling early phase requirements that is particularly effective in capturing...
Co-evolution of i* Models and 3APL Agents (2006)
Krishna, A., Guan, Y., Ghose, A.
Agent-Oriented Conceptual Modelling (AOCM), as exemplified by the i* notation [9], represents an interesting approach to modelling early phase requirements that is particularly effective in capturing...
Using constraint hierarchies to support QoS-guided service composition (2006)
A key impediment to the widespread adoption of web services is the is the relatively limited set of tools available to deal with Quality-of-Service (QoS) factors [12]. QoS factors pose several...
Using Assumptions in Service Composition Context (2006)
Lu, Z., Ghose, A., Hyland, P., Guan, Y.
Service composition aims to provide the efficient and accurate model of a service, based on which the global service oriented architecture (SOA) can be realized, allowing the value-added services to...
Using constraint hierarchies to support QoS-guided service composition (2006)
A key impediment to the widespread adoption of web services is the is the relatively limited set of tools available to deal with Quality-of-Service (QoS) factors [12]. QoS factors pose several...
Using Assumptions in Service Composition Context (2006)
Lu, Z., Ghose, A., Hyland, P., Guan, Y.
Service composition aims to provide the efficient and accurate model of a service, based on which the global service oriented architecture (SOA) can be realized, allowing the value-added services to...
Weakly Coupled Motion of Individual Layers in Ferromagnetic Resonance (2006)
Arena, D. A., Vescovo, E., Guan, Y., Bailey, W. E.
We demonstrate a layer- and time-resolved measurement of ferromagnetic resonance (FMR) in a Ni81Fe19 / Cu / Co93Zr7 trilayer structure. Time-resolved x-ray magnetic circular dichroism has been...
Time-domain measurement of driven ferromagnetic resonance (2006)
Guan, Y., Bailey, W. E., Vescovo, E., Arena, D. A.
We present a time-resolved measurement of magnetization dynamics during ferromagnetic resonance (FMR) in a single layer of Ni81Fe19. Small-angle (
Research article - Comet 81P/Wild 2 under a microscope (2006)
Brownlee, D., Tsou, P., Aleon, J., Alexander, C. M. O., Araki, T., Bajt, S., ...
HCLP Based Service Composition (2006)
A key impediment to the widespread adoption of web services is the relatively limited set of tools available to deal with Quality-of-Service (QoS) factors. QoS factors pose several difficult...
Co-evolution of i* Models and 3APL Agents (2006)
Krishna, A., Guan, Y., Ghose, A.
Agent-Oriented Conceptual Modelling (AOCM), as exemplified by the i* notation [9], represents an interesting approach to modelling early phase requirements that is particularly effective in capturing...
Using constraint hierarchies to support QoS-guided service composition (2006)
A key impediment to the widespread adoption of web services is the is the relatively limited set of tools available to deal with Quality-of-Service (QoS) factors [12]. QoS factors pose several...
Using Assumptions in Service Composition Context (2006)
Lu, Z., Ghose, A., Hyland, P., Guan, Y.
Service composition aims to provide the efficient and accurate model of a service, based on which the global service oriented architecture (SOA) can be realized, allowing the value-added services to...
Distribution of amantadine-resistant H5N1 avian influenza variants in Asia (2006)
Cheung, CL, Rayner, JM, Smith, GJ, Wang, P, Naipospos, TS, Zhang, J, ...
We examined the distribution of genetic mutations associated with resistance to the M2 ion channel-blocking adamantane derivatives, amantadine and rimantadine, among H5N1 viruses isolated in Vietnam,...
Three Indonesian clusters of H5N1 virus infection in 2005 (2006)
Kandun, IN, Wibisono, H, Sedyaningsih, ER, Hadisoedarsuno, W, Purba, W, ...
BACKGROUND: Since 2003, the widespread ongoing epizootic of avian influenza A (H5N1) among poultry and birds has resulted in human H5N1 cases in 10 countries. The first case of H5N1 virus infection...
Zheng, BJ, Guan, Y, Huang, J, He, ML
The present invention provides methods for locating critical portions or sites on the spike protein (S protein) of SARS-associated coronavirus (SARS-CoV) responsible for the viral infection that...
Kung, HF, He, ML, Zheng, BJ, Guan, Y, Lin, MCM, Peng, Y
The present invention relates to therapeutic agents useful for the treatment of Severe Acute Respiratory Syndrome (SARS) in humans. In particular, the present invention relates to RNA interference...
Comet 81P/Wild 2 under a microscope (2006)
Brownlee, D., Tsou, P., Aleon, J., Alexander, C. M. O., Araki, T., Bajt, S., ...
Chan, MCW, Cheung, CY, Chui, WH, Tsao, SW, Nicholls, JM, Chan, YO, ...
Abstract Background Fatal human respiratory disease associated with influenza A subtype H5N1 has been documented in Hong Kong, and more recently in Vietnam, Thailand and Cambodia. We previously...
Executable specifications for agent oriented conceptual modelling (2005)
Agent-oriented conceptual modelling (AoCM) notations such as i* have received considerable recent attention as a useful approach to early-phase requirements engineering. AoCM notations are useful in...
Executable specifications for agent oriented conceptual modelling (2005)
Agent-oriented conceptual modelling (AoCM) notations such as i* have received considerable recent attention as a useful approach to early-phase requirements engineering. AoCM notations are useful in...
Synthesis of supramolecular polymers by ionic self-assembly of oppositely charged dyes (2005)
Guan, Y., Yu, S. H., Antonietti, M., Bottcher, C., Faul, C. F. J.
Executable specifications for agent oriented conceptual modelling (2005)
Agent-oriented conceptual modelling (AoCM) notations such as i* have received considerable recent attention as a useful approach to early-phase requirements engineering. AoCM notations are useful in...
Chiu, SSS, Chan, KH, Chu, KW, Kwan, SW, Guan, Y, Poon, LLM, ...
Background. Human coronavirus NL63 (HCoV-NL63) is a recently discovered human coronavirus found to cause respiratory illness in children and adults that is distinct from the severe acute respiratory...
Chan, MC, Cheung, CY, Chui, WH, Tsao, GSW, Nicholls, JM, Chan, YO, ...
BACKGROUND: Fatal human respiratory disease associated with influenza A subtype H5N1 has been documented in Hong Kong, and more recently in Vietnam, Thailand and Cambodia. We previously demonstrated...
Woo, PCY, Lau, SKP, Tsoi, HW, Huang, Y, Poon, RW, Chu, CM, ...
BACKGROUND: Recently, we described the discovery of a novel group 2 coronavirus, coronavirus HKU1 (CoV-HKU1), from a patient with pneumonia. However, the clinical and molecular epidemiological...
Oseltamivir resistance during treatment of influenza A (H5N1) infection (2005)
De Jong, MD, Thanh, TT, Khanh, TH, Hien, VM, Smith, GJD, Chau, NV, ...
Influenza A (H5N1) virus with an amino acid substitution in neuraminidase conferring high-level resistance to oseltamivir was isolated from two of eight Vietnamese patients during oseltamivir...
Oseltamivir Resistance during Treatment of Influenza A (H5N1) Infection (2005)
De Jong, MD, Thanh, TT, Khanh, TH, Hien, VM, Smith, GJD, Chau, NV, ...
Influenza A (H5N1) virus with an amino acid substitution in neuraminidase conferring high-level resistance to oseltamivir was isolated from two of eight Vietnamese patients during oseltamivir...
Cheung, TKW, Guan, Y, Ng, SSF, Chen, H, Wong, CHK, Peiris, JSM, ...
The aim of this study was to inhibit influenza virus M2 protein expression by mutating the splicing signal of the M gene. Mutations were introduced into the GU dinucleotide sequence at the...
Woo, PCY, Lau, SKP, Chu, CM, Chan, KH, Tsoi, HW, Huang, Y, ...
Despite extensive laboratory investigations in patients with respiratory tract infections, no microbiological cause can be identified in a significant proportion of patients. In the past 3 years,...
Cheung, CY, Poon, LLM, Ng, IHY, Luk, W, Sia, SF, Wu, MHS, ...
The pathogenesis of severe acute respiratory syndrome (SARS) remains unclear. Macrophages are key sentinel cells in the respiratory system, and it is therefore relevant to compare the responses of...
Lethality to ferrets of H5N1 influenza viruses isolated from humans and poultry in 2004 (2005)
Govorkova, EA, Rehg, JE, Krauss, S, Yen, HL, Guan, Y, Peiris, M, ...
Erratum in: Journal of Virology 2006 Jun;80(12):6195
Identification of a novel coronavirus in bats (2005)
Poon, LLM, Chu, DKW, Chan, KH, Wong, OK, Ellis, TM, Leung, YHC, ...
Exotic wildlife can act as reservoirs of diseases that are endemic in the area or can be the source of new emerging diseases through interspecies transmission. The recent emergence of severe acute...
Detection of human influenza A viruses by loop-mediated isothermal amplification (2005)
Poon, LLM, Leung, CSW, Chan, KH, Lee, JHC, Yuen, KY, Guan, Y, ...
Here we describe the use of the loop-mediated isothermal amplification (LAMP) method to detect human influenza viruses (H1 to H3). Our results were correlated 100% with results deduced from routine...
Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2 (2005)
Li, WS, Zhang, C, Sui, J, Kuhn, JH, Moore, MJ, Luo, S, ...
Human angiotensin-converting enzyme 2 (ACE2) is a functional receptor for SARS coronavirus (SARS-CoV). Here we identify the SARS-CoV spike (S)-protein-binding site on ACE2. We also compare S proteins...
Poon, LLM, Wong, BWY, Chan, KH, Ng, SSF, Yuen, KY, Guan, Y, ...
We compared the performance of a recently established real-time loop-mediated amplification (LAMP) assay with the one from a highly sensitive quantitative PCR assay. None of these assays produced...
Kan, B, Wang, M, Jing, H, Xu, H, Jiang, X, Yan, M, ...
Erratum in: Journal of Virology 2006 Aug;80(15):7786
Are ducks contributing to the endemicity of highly pathogenic H5N1 influenza virus in Asia? (2005)
Sturm-Ramirez, KM, Hulse-Post, DJ, Govorkova, EA, Humberd, J, Seiler, P, Puthavathana, P, ...
Wild waterfowl are the natural reservoir of all influenza A viruses, and these viruses are usually nonpathogenic in these birds. However, since late 2002, H5N1 outbreaks in Asia have resulted in...
Choi, YK, Nguyen, TD, Ozaki, H, Webby, RJ, Puthavathana, P, Buranathal, C, ...
To determine whether avian H5N1 influenza viruses associated with human infections in Vietnam had transmitted to pigs, we investigated serologic evidence of exposure to H5N1 influenza virus in...
Characterization of a human H5N1 influenza A virus isolated in 2003 (2005)
Shinya, K, Hatta, M, Yamada, S, Takada, A, Watanabe, S, Halfmann, P, ...
In 2003, H5N1 avian influenza virus infections were diagnosed in two Hong Kong residents who had visited the Fujian province in mainland China, affording us the opportunity to characterize one of the...
Chan, KH, Cheng, VCC, Woo, PCY, Lau, SKP, Poon, LLM, Guan, Y, ...
The serological response profile of severe acute respiratory syndrome (SARS) coronavirus (CoV) infection was defined by neutralization tests and subclass-specific immunofluorescent (IF) tests using...
Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003 (2005)
Butt, KM, Smith, GJD, Chen, H, Zhang, LJ, Leung, CYH, Xu, KM, ...
Avian H9N2 influenza A virus has caused repeated human infections in Asia since 1998. Here we report that an H9N2 influenza virus infected a 5-year-old child in Hong Kong in 2003. To identify the...
Zakrevskyy, Y., Faul, C.F.J., Guan, Y., Stumpe, J.
The thermotropic and lyotropic liquid-crystalline (LC) phases of the ionic self-assembled complex N,N',-bis(2-(trimethylammonium)...
Chu, CM, Cheng, VCC, Hung, IFN, Wong, MML, Chan, KH, Chan, KS, ...
Background: The clinical response of patients with severe acute respiratory syndrome (SARS) to a combination of lopinavir/ritonavir and ribavirin was examined after establishing the in vitro...
H5N1 influenza: a protein pandemic threat (2004)
Guan, Y, Poon, LLM, Cheung, CY, Ellis, TM, Lim, W, Lipatov, AS, ...
Infection with avian influenza A virus of the H5N1 subtype (isolates A/HK/212/03 and A/HK/213/03) was fatal to one of two members of a family in southern China in 2003. This incident was preceded by...
Reemerging H5N1 influenza viruses in Hong Kong in 2002 are highly pathogenic to ducks (2004)
Sturm-Ramirez, KM, Ellis, T, Bousfield, B, Bissett, L, Dyrting, K, Rehg, JE, ...
Waterfowl are the natural reservoir of all influenza A viruses, which are usually nonpathogenic in wild aquatic birds. However, in late 2002, outbreaks of highly pathogenic H5N1 influenza virus...
Influenza: emergence and control (2004)
Lipatov, AS, Govorkova, EA, Webby, RJ, Ozaki, H, Peiris, M, Guan, Y, ...
Confronting SARS: a view from Hong Kong (2004)
Severe acute respiratory syndrome (SARS) emerged as a new disease in Guangdong Province, People's Republic of China in late 2002. Within weeks it had spread to Hong Kong and thence globally to affect...
Continuing evolution of H9N2 influenza viruses in southeastern China (2004)
Choi, YK, Ozaki, H, Webby, RJ, Webster, RG, Peiris, JS, Poon, L, ...
H9N2 influenza viruses are panzootic in domestic poultry in Eurasia and since 1999 have caused transient infections in humans and pigs. To investigate the zoonotic potential of H9N2 viruses, we...
Guan, Y., Zakrevskyy, Y., Stumpe, J., Antonietti, M., Faul, C.F.J.
In this communication we present the facile preparation and characterisation of thermotropic liquid-crystalline materials from the ionic self-assembly of a charged perylenediimide derivative and...
Li, KS, Xu, KM, Peiris, JSM, Poon, LLM, Yu, KZ, Yuen, KY, ...
A current view of the emergence of pandemic influenza viruses envisages a gene flow from the aquatic avian reservoir to humans via reassortment in pigs, the hypothetical 'mixing vessel.'...