Y. Ihara

Publication List Details

Period

2003 - 2008

Number

39

Co-Authors

Discovery of an Unusual Optical Transient with the Hubble Space Telescope (2008)

Barbary, K., Dawson, K. S., Tokita, K., Aldering, G., Amanullah, R., Connolly, N. V., ...

We present observations of SCP 06F6, an unusual optical transient discovered during the Hubble Space Telescope Cluster Supernova Survey. The transient brightened over a period of ~100 days, reached a...

Spin dynamics and spin freezing behavior in the two-dimensional antiferromagnet NiGa$_{2}$S$_{4}$ revealed by Ga-NMR, NQR and $\mu$SR measurements (2007)

Takeya, H., Ishida, K., Kitagawa, K., Ihara, Y., Onuma, K., Maeno, Y., ...

We have performed $^{69,71}$Ga nuclear magnetic resonance (NMR) and nuclear quadrupole resonance (NQR) and muon spin rotation/resonance on the quasi two-dimensional antiferromagnet (AFM)...

The Sloan Digital Sky Survey-II Supernova Survey: Technical Summary (2007)

Frieman, Joshua A., Bassett, B., Becker, A., Choi, C., Cinabro, D., DeJongh, F., ...

The Sloan Digital Sky Survey-II (SDSS-II) has embarked on a multi-year project to identify and measure light curves for intermediate-redshift (0.05 < z < 0.35) Type Ia supernovae (SNe Ia) using...

The Sloan Digital Sky Survey-II Supernova Survey: Search Algorithm and Follow-up Observations (2007)

Sako, Masao, Bassett, B., Becker, A., Cinabro, D., DeJongh, F., Depoy, D. L., ...

The Sloan Digital Sky Survey-II Supernova Survey has identified a large number of new transient sources in a 300 sq. deg. region along the celestial equator during its first two seasons of a...

Rest-Frame R-band Lightcurve of a z~1.3 Supernova Obtained with Keck Laser Adaptive Optics (2007)

Melbourne, J., Dawson, K. S., Koo, D. C., Max, C., Larkin, J. E., Wright, S. A., ...

We present Keck diffraction limited H-band photometry of a z~1.3 Type Ia supernova (SN) candidate, first identified in a Hubble Space Telescope (HST) search for SNe in massive high redshift galaxy...

Anisotropic Behavior of Knight Shift in Superconducting State of Na_xCoO_2yH_2O (2005)

Ihara, Y., Ishida, K., Takeya, H., Michioka, C., Kato, M., Itoh, Y., ...

The Co Knight shift was measured in an aligned powder sample of Na_xCoO_2yH_2O, which shows superconductivity at T_c \sim 4.6 K. The Knight-shift components parallel (K_c) and perpendicular to the...

Weak Magnetic Order in the Bilayered-hydrate Na$_{x}$CoO$_{2}\cdot y$H$_{2}$O Structure Probed by Co Nuclear Quadrupole Resonance - Proposed Phase Diagram in Superconducting Na$_x$CoO$_{2} \cdot$ $y$H$_2$O (2004)

Ihara, Y., Ishida, K., Michioka, C., Kato, M., Yoshimura, K., Takada, K., ...

A weak magnetic order was found in a non-superconducting bilayered-hydrate Na$_{x}$CoO$_{2}\cdot y$H$_{2}$O sample by a Co Nuclear Quadrupole Resonance (NQR) measurement. The nuclear spin-lattice...

Correlation between Superconducting Transition Temperature $T_c$ and Increase of Nuclear Spin-Lattice Relaxation Rate Devided by Temperature $1/T_1T$ at $T_c$ in the Hydrate Cobaltate Na$_{x}$CoO$_{2}\cdot y$H$_{2}$O (2004)

Ihara, Y., Ishida, K., Michioka, C., Kato, M., Yoshimura, K., Takada, K., ...

We have performed Co-nuclear quadrupole resonance (NQR) studies on Na$_{x}$CoO$_{2}\cdot y$H$_{2}$O compounds with different Na ($x$) and hydrate ($y$) contents. Two samples with different Na...

Magnetic Fluctuations in the Metallic State of Na$_{0.7}$CoO$_2$ Revealed by $^{23}$Na NMR (2004)

Ihara, Y., Ishida, K., Michioka, C., Kato, M., Yoshimura, K., Sakurai, H., ...

Nuclear-magnetic-resonance (NMR) studies were performed in Na$_{0.7}$CoO$_2$ to investigate its magnetic properties from the microscopic point of view. Na$_{0.7}$CoO$_2$ is a starting compound of the...

Unconventional Superconductivity and Nearly Ferromagnetic Spin Fluctuations in Na$_x$CoO$_2$$\cdot y$H$_2$O (2003)

Ishida, K., Ihara, Y., Maeno, Y., Michioka, C., Kato, M., Yoshimura, K., ...

Co NQR studies were performed in recently discovered superconductor Na$_x$CoO$_2$$\cdot y$H$_2$O to investigate physical properties in the superconducting (SC) and normal states. Two samples from the...

Suppression of lung metastasis of B16 mouse melanoma by N-acetylglucosaminyltransferase III gene transfection.

Yoshimura, M, Nishikawa, A, Ihara, Y, Taniguchi, S, Taniguchi, N

The beta 1-6 structure of N-linked oligosaccharides, formed by beta-1,6-N-acetylglucosaminyltransferase (GnT-V), is associated with metastatic potential. We established a highly metastatic subclone,...

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.

Uéda, K, Fukushima, H, Masliah, E, Xia, Y, Iwai, A, Yoshimoto, M, ...

A neuropathological hallmark of Alzheimer disease (AD) is a widespread amyloid deposition. We analyzed the entire amino acid sequences in an amyloid preparation and found, in addition to the major...

Recovery of active beta-lactamases from Proteus vulgaris and RTEM-1 hybrid by random mutagenesis by using a dnaQ strain of Escherichia coli.

Hosseini-Mazinani, S M, Nakajima, E, Ihara, Y, Kameyama, K Z, Sugimoto, K

Proteus vulgaris and RTEM-1 beta-lactamases that belong to molecular class A with 37% amino acid similarity were examined to find the relationship between amino acid residues and activity of enzymes....

Brain transglutaminase: in vitro crosslinking of human neurofilament proteins into insoluble polymers.

Selkoe, D J, Abraham, C, Ihara, Y

The accumulation in aged human neurons of insoluble, high molecular weight filamentous polymers apparently linked by nondisulfide covalent bonds led us to examine human brain for the presence of...

Mucinous cystadenoma of the appendix with raised serum carcinoembryonic antigen concentration: clinical and pathological features.

Shimizu, T, Shimizu, M, Kawaguchi, K, Yomura, W, Ihara, Y, Matsumoto, T

A case of mucinous cystadenoma mimicking ovarian cancer is reported. Serum carcinoembryonic antigen (CEA) concentration was raised, and computed tomography of the abdomen and pelvis demonstrated a...

Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease.

Tsuji, S, Kobayashi, H, Uchida, Y, Ihara, Y, Miyatake, T

In previous studies, we discovered a growth inhibitory factor (GIF) that was abundant in normal human brain, but greatly reduced in Alzheimer's disease (AD) brain. Molecular cloning of a full-length...

Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins.

Saito, Y, Ihara, Y, Leach, M R, Cohen-Doyle, M F, Williams, D B

Calreticulin (CRT) is thought to be a molecular chaperone that interacts with glycoproteins exclusively through a lectin site specific for monoglucosylated oligosaccharides. However, this chaperone...

Bisecting GlcNAc structure is implicated in suppression of stroma-dependent haemopoiesis in transgenic mice expressing N-acetylglucosaminyltransferase III.

Yoshimura, M, Ihara, Y, Nishiura, T, Okajima, Y, Ogawa, M, Yoshida, H, ...

Several sugar structures have been reported to be necessary for haemopoiesis. We analysed the haematological phenotypes of transgenic mice expressing beta-1,4 N-acetylglucosaminyltransferase III...

Suppression of lung metastasis of B16 mouse melanoma by N-acetylglucosaminyltransferase III gene transfection.

Yoshimura, M, Nishikawa, A, Ihara, Y, Taniguchi, S, Taniguchi, N

The beta 1-6 structure of N-linked oligosaccharides, formed by beta-1,6-N-acetylglucosaminyltransferase (GnT-V), is associated with metastatic potential. We established a highly metastatic subclone,...

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.

Uéda, K, Fukushima, H, Masliah, E, Xia, Y, Iwai, A, Yoshimoto, M, ...

A neuropathological hallmark of Alzheimer disease (AD) is a widespread amyloid deposition. We analyzed the entire amino acid sequences in an amyloid preparation and found, in addition to the major...

Recovery of active beta-lactamases from Proteus vulgaris and RTEM-1 hybrid by random mutagenesis by using a dnaQ strain of Escherichia coli.

Hosseini-Mazinani, S M, Nakajima, E, Ihara, Y, Kameyama, K Z, Sugimoto, K

Proteus vulgaris and RTEM-1 beta-lactamases that belong to molecular class A with 37% amino acid similarity were examined to find the relationship between amino acid residues and activity of enzymes....

Brain transglutaminase: in vitro crosslinking of human neurofilament proteins into insoluble polymers.

Selkoe, D J, Abraham, C, Ihara, Y

The accumulation in aged human neurons of insoluble, high molecular weight filamentous polymers apparently linked by nondisulfide covalent bonds led us to examine human brain for the presence of...

Mucinous cystadenoma of the appendix with raised serum carcinoembryonic antigen concentration: clinical and pathological features.

Shimizu, T, Shimizu, M, Kawaguchi, K, Yomura, W, Ihara, Y, Matsumoto, T

A case of mucinous cystadenoma mimicking ovarian cancer is reported. Serum carcinoembryonic antigen (CEA) concentration was raised, and computed tomography of the abdomen and pelvis demonstrated a...

Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease.

Tsuji, S, Kobayashi, H, Uchida, Y, Ihara, Y, Miyatake, T

In previous studies, we discovered a growth inhibitory factor (GIF) that was abundant in normal human brain, but greatly reduced in Alzheimer's disease (AD) brain. Molecular cloning of a full-length...

Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins.

Saito, Y, Ihara, Y, Leach, M R, Cohen-Doyle, M F, Williams, D B

Calreticulin (CRT) is thought to be a molecular chaperone that interacts with glycoproteins exclusively through a lectin site specific for monoglucosylated oligosaccharides. However, this chaperone...

Bisecting GlcNAc structure is implicated in suppression of stroma-dependent haemopoiesis in transgenic mice expressing N-acetylglucosaminyltransferase III.

Yoshimura, M, Ihara, Y, Nishiura, T, Okajima, Y, Ogawa, M, Yoshida, H, ...

Several sugar structures have been reported to be necessary for haemopoiesis. We analysed the haematological phenotypes of transgenic mice expressing beta-1,4 N-acetylglucosaminyltransferase III...

Astrocytes containing amyloid beta-protein (Abeta)-positive granules are associated with Abeta40-positive diffuse plaques in the aged human brain.

Funato, H., Yoshimura, M., Yamazaki, T., Saido, T. C., Ito, Y., Yokofujita, J., ...

Amyloid beta-protein (Abeta) is the major component of senile plaques that emerge in the cortex during aging and appear most abundantly in Alzheimer's disease. In the course of our immunocytochemical...

Quantitation of amyloid beta-protein (A beta) in the cortex during aging and in Alzheimer's disease.

Funato, H., Yoshimura, M., Kusui, K., Tamaoka, A., Ishikawa, K., Ohkoshi, N., ...

In this study we sought to learn about when and how amyloid beta-protein (A beta) accumulates in the cortex of normal individuals and about the difference in the A beta accumulation between normal...

Predominant deposition of amyloid-beta 42(43) in plaques in cases of Alzheimer's disease and hereditary cerebral hemorrhage associated with mutations in the amyloid precursor protein gene.

Mann, D. M., Iwatsubo, T., Ihara, Y., Cairns, N. J., Lantos, P. L., Bogdanovic, N., ...

Amyloid (A beta) deposition was investigated in cases of Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis, Dutch type, due to mutations in the amyloid precursor protein (APP)...

Purification and characterization of Lewy bodies from the brains of patients with diffuse Lewy body disease.

Iwatsubo, T., Yamaguchi, H., Fujimuro, M., Yokosawa, H., Ihara, Y., Trojanowski, J. Q., ...

Lewy bodies (LBs) are the pathological hallmarks of degenerating neurons in the brains of patients with Parkinson's disease and diffuse Lewy body disease. We developed a novel purification procedure...

Transient ischemia depletes free ubiquitin in the gerbil hippocampal CA1 neurons.

Morimoto, T., Ide, T., Ihara, Y., Tamura, A., Kirino, T.

We investigated ubiquitin immunoreactivity in the post-ischemic gerbil hippocampus using a panel of ubiquitin antibodies. Immunostaining for ubiquitin in the hippocampus was strongly dependent on the...

Amyloid beta protein deposition in normal aging has the same characteristics as that in Alzheimer's disease. Predominance of A beta 42(43) and association of A beta 40 with cored plaques.

Fukumoto, H., Asami-Odaka, A., Suzuki, N., Shimada, H., Ihara, Y., Iwatsubo, T.

Two distinct species of amyloid beta protein (A beta) with different C-termini, A beta 42(43) and A beta 40, are deposited in senile plaques (SP) of Alzheimer's disease (AD), with the former being...

The presence of a novel protein in calf serum that recognizes beta amyloid in the formalin-fixed section.

Kanemaru, K., Hasegawa, M., Shimada, H., Ihara, Y.

Here we report on a monoclonal antibody, H6-33, that labels various beta-amyloid plaques, including diffuse plaques in the formalin-fixed, paraffin-embedded section from the brain affected with...

Secondary deposition of beta amyloid within extracellular neurofibrillary tangles in Alzheimer-type dementia.

Yamaguchi, H., Nakazato, Y., Shoji, M., Okamoto, K., Ihara, Y., Morimatsu, M., ...

The hippocampal areas of 34 autopsy specimen brains from aged demented and nondemented subjects were examined using double staining of Bodian and beta protein. In 18 cases (75.5 +/- 7.4 years old),...

Lack of ubiquitin immunoreactivities at both ends of neuropil threads. Possible bidirectional growth of neuropil threads.

Iwatsubo, T., Hasegawa, M., Esaki, Y., Ihara, Y.

Immunocytochemically, neuropil threads (curly fibers) were investigated in the Alzheimer's disease brain using a confocal laser scanning fluorescence microscope by double labeling with tau/ubiquitin...

High tissue content of soluble beta 1-40 is linked to cerebral amyloid angiopathy.

Suzuki, N., Iwatsubo, T., Odaka, A., Ishibashi, Y., Kitada, C., Ihara, Y.

We developed two highly sensitive enzyme immunoassays for beta-protein with different specificities. One is specific for beta 1-40, while the other is equally sensitive to beta 1-38, beta 1-39, beta...

Expression of neurofilament triplet proteins in human neural tumors. An immunohistochemical study of paraganglioma, ganglioneuroma, ganglioneuroblastoma, and neuroblastoma.

Mukai, M., Torikata, C., Iri, H., Morikawa, Y., Shimizu, K., Shimoda, T., ...

Intermediate filaments which are specific to neural cells, ie, neurofilaments, consist of three subcomponents--68, 150, and 200 kd. Thirty human neural tumors were examined for the presence of these...