Tanaka, Y, Koyanagi, Y, Tanaka, R, Kumazawa, Y, Nishimura, T, Yamamoto, N
It is generally recognized that macrophage-tropic human immunodeficiency virus type 1 (HIV-1) is the predominant population during the acute and asymptomatic phases of HIV-1 infection. Here, we...
Koyanagi, Y, Tanaka, Y, Kira, J, Ito, M, Hioki, K, Misawa, N, ...
We established four new mouse strains with defective T and B cells as well as defects in innate immunological reactions using an NK cell depletion antibody and showed that all mutant mouse strains...
Gamma interferon production in endotoxin-responder and -nonresponder mice during infection.
Freudenberg, M A, Kumazawa, Y, Meding, S, Langhorne, J, Galanos, C
The production of gamma interferon (IFN-gamma) in response to infection and to a number of other agents was compared in Lpsn (C3H/HeN and C57BL/10ScSn) and Lpsd (C3H/HeJ and C57BL/10ScCr) mouse...
Kumazawa, Y, Nakatsuka, M, Takimoto, H, Furuya, T, Nagumo, T, Yamamoto, A, ...
The immunopharmacological activities of chemically synthesized lipid A-subunit analogs, 4-O-phosphono-D-glucosamine derivatives carrying different N- and 3-O-linked acyl groups, were investigated....
Furuya, T, Kumazawa, Y, Takimoto, H, Nagumo, T, Watanabe, M, Aizawa, C, ...
The adjuvant activity of chemically synthesized 6-O-acylated muramyl dipeptides (MDP) was tested in aqueous form. The activity was assessed by determining immunoglobulin G (IgG) titers in sera of...
Kumazawa, Y, Matsuura, M, Homma, J Y, Furuya, T, Takimoto, H, Inagaki, K, ...
The immunopharmacological activities of 2-keto-3-deoxyoctonic acid (KDO)-(alpha 2----6)-linked lipid A-subunit analogs, 4-O-phosphono-D-glucosamine derivatives carrying N- and 3-O-acyl substituents,...
Yokogawa, T, Kumazawa, Y, Miura, K, Watanabe, K
For large scale preparation of mitochondrial tRNAs, a new hybridization assay method using synthetic oligodeoxyribonucleotide probes (16-17mer) complementary to individual tRNA sequences was...
A novel cloverleaf structure found in mammalian mitochondrial tRNA(Ser) (UCN).
Yokogawa, T, Watanabe, Y, Kumazawa, Y, Ueda, T, Hirao, I, Miura, K, ...
Bovine mitochondrial tRNA(Ser) (UCN) has been thought to have two U-U mismatches at the top of the acceptor stem, as inferred from its gene sequence. However, this unusual structure has not been...
Watanabe, Y, Kawai, G, Yokogawa, T, Hayashi, N, Kumazawa, Y, Ueda, T, ...
On the basis of enzymatic probing and phylogenetic comparison, we have previously proposed that mammalian mitochondrial tRNA(sSer) (anticodon UGA) possess a slightly altered cloverleaf structure in...
Wakita, K, Watanabe, Y, Yokogawa, T, Kumazawa, Y, Nakamura, S, Ueda, T, ...
Bovine mitochondrial (mt) phenylalanine tRNA (tRNA(Phe)), which lacks the 'conserved' GG and T psi YCG sequences, was efficiently purified by the selective hybridization method using a solid phase...
Kumazawa, Y, Maeda, K, Ito, M, Yamakawa, M, Hino, T, Nakamura, C, ...
This report describes a case of pulmonary epithelioid haemangioendothelioma in which the tumour cells expressed the glucocorticoid receptor and 11β-hydroxysteroid dehydrogenase. The patient, a 15...
Kumazawa, Y, Yokogawa, T, Tsurui, H, Miura, K, Watanabe, K
In the course of developing a method to purify a single tRNA species efficiently, we have examined hybridization efficiencies between some tRNAs and short oligodeoxyribonucleotide probes both by the...
Kumazawa, Y, Ota, H, Nishida, M, Ozawa, T
The 17,191-bp mitochondrial DNA (mtDNA) of a Japanese colubrid snake, akamata (Dinodon semicarinatus), was cloned and sequenced. The snake mtDNA has some peculiar features that were found in our...
Tanaka, Y, Koyanagi, Y, Tanaka, R, Kumazawa, Y, Nishimura, T, Yamamoto, N
It is generally recognized that macrophage-tropic human immunodeficiency virus type 1 (HIV-1) is the predominant population during the acute and asymptomatic phases of HIV-1 infection. Here, we...
Koyanagi, Y, Tanaka, Y, Kira, J, Ito, M, Hioki, K, Misawa, N, ...
We established four new mouse strains with defective T and B cells as well as defects in innate immunological reactions using an NK cell depletion antibody and showed that all mutant mouse strains...
Gamma interferon production in endotoxin-responder and -nonresponder mice during infection.
Freudenberg, M A, Kumazawa, Y, Meding, S, Langhorne, J, Galanos, C
The production of gamma interferon (IFN-gamma) in response to infection and to a number of other agents was compared in Lpsn (C3H/HeN and C57BL/10ScSn) and Lpsd (C3H/HeJ and C57BL/10ScCr) mouse...
Kumazawa, Y, Nakatsuka, M, Takimoto, H, Furuya, T, Nagumo, T, Yamamoto, A, ...
The immunopharmacological activities of chemically synthesized lipid A-subunit analogs, 4-O-phosphono-D-glucosamine derivatives carrying different N- and 3-O-linked acyl groups, were investigated....
Kumazawa, Y, Yokogawa, T, Tsurui, H, Miura, K, Watanabe, K
In the course of developing a method to purify a single tRNA species efficiently, we have examined hybridization efficiencies between some tRNAs and short oligodeoxyribonucleotide probes both by the...
Furuya, T., Kumazawa, Y., Takimoto, H., Nagumo, T., Watanabe, M., Aizawa, C., ...
The adjuvant activity of chemically synthesized 6-O-acylated muramyl dipeptides (MDP) was tested in aqueous form. The activity was assessed by determining immunoglobulin G (IgG) titers in sera of...
Kumazawa, Y., Matsuura, M., Homma, J. Y., Furuya, T., Takimoto, H., Inagaki, K., ...
The immunopharmacological activities of 2-keto-3-deoxyoctonic acid (KDO)-(alpha 2----6)-linked lipid A-subunit analogs, 4-O-phosphono-D-glucosamine derivatives carrying N- and 3-O-acyl substituents,...
Yokogawa, T, Kumazawa, Y, Miura, K, Watanabe, K
For large scale preparation of mitochondrial tRNAs, a new hybridization assay method using synthetic oligodeoxyribonucleotide probes (16-17mer) complementary to individual tRNA sequences was...
A novel cloverleaf structure found in mammalian mitochondrial tRNA(Ser) (UCN).
Yokogawa, T, Watanabe, Y, Kumazawa, Y, Ueda, T, Hirao, I, Miura, K, ...
Bovine mitochondrial tRNA(Ser) (UCN) has been thought to have two U-U mismatches at the top of the acceptor stem, as inferred from its gene sequence. However, this unusual structure has not been...
Watanabe, Y, Kawai, G, Yokogawa, T, Hayashi, N, Kumazawa, Y, Ueda, T, ...
On the basis of enzymatic probing and phylogenetic comparison, we have previously proposed that mammalian mitochondrial tRNA(sSer) (anticodon UGA) possess a slightly altered cloverleaf structure in...
Wakita, K, Watanabe, Y, Yokogawa, T, Kumazawa, Y, Nakamura, S, Ueda, T, ...
Bovine mitochondrial (mt) phenylalanine tRNA (tRNA(Phe)), which lacks the 'conserved' GG and T psi YCG sequences, was efficiently purified by the selective hybridization method using a solid phase...
Kumazawa, Y, Maeda, K, Ito, M, Yamakawa, M, Hino, T, Nakamura, C, ...
This report describes a case of pulmonary epithelioid haemangioendothelioma in which the tumour cells expressed the glucocorticoid receptor and 11β-hydroxysteroid dehydrogenase. The patient, a 15...
Kumazawa, Y, Ota, H, Nishida, M, Ozawa, T
The 17,191-bp mitochondrial DNA (mtDNA) of a Japanese colubrid snake, akamata (Dinodon semicarinatus), was cloned and sequenced. The snake mtDNA has some peculiar features that were found in our...
Machida, A., Kumazawa, Y., Mizunoe, K.
The i.p. immunization with chemically modified antigen (dodecanoyl-bovine serum albumin, d-BSA) emulsified in Freund's incomplete adjuvant (FIA) of CBA mice provoked delayed-type hypersensitivity...
High frequency detection of different T-cell subsets in mice by a modified virus plaque assay.
Fujisawa, H, Kumazawa, Y, Ohtani, A, Nishimura, C
Different T-cell subsets participating in immune responses were detected at a high frequency by a modified virus plaque assay (VPA). By using the modified VPA, different activated T-cell subsets...
Kumazawa, Y, Mizunoe, K, Otsuka, Y
Separation of immunostimulating polysaccharide (ATP) from Angelica and its biological activities were investigated. AIP was separated as an acetone-insoluble and non-dialysable fraction from hot...
NAGAYAMA, Y, SAITOH, O, MCLACHLAN, S M, RAPOPORT, B, KANO, H, KUMAZAWA, Y
The role of the Th1/Th2 balance in the pathogenesis of murine Graves' hyperthyroidism is controversial. In BALB/c mice injected with adenovirus expressing TSH receptor (TSHR-adeno model), we found...
Takimoto, H, Maruyama, H, Shimada, K-I, Yakabe, R, Yano, I, Kumazawa, Y
The mechanisms by which pulmonary granuloma formation is caused by administration of mycobacterial glycolipids such as trehalose dimycolate (TDM), lipoarabinomannan (LAM) and phosphatidylinositol...