Y. Misumi

Publication List Details

Period

2000 - 2004

Number

34

Co-Authors

Nuclear factors interacting with an interleukin-6 responsive element of rat alpha 2-macroglobulin gene.

Ito, T, Tanahashi, H, Misumi, Y, Sakaki, Y

During acute inflammation, a group of liver-derived plasma proteins, acute phase proteins (APPs), increase in concentration. Interleukin-6 (IL-6) is responsible for this increase via the induction of...

Conversion of secretory proteins into membrane proteins by fusing with a glycosylphosphatidylinositol anchor signal of alkaline phosphatase.

Oda, K, Cheng, J, Saku, T, Takami, N, Sohda, M, Misumi, Y, ...

Placental alkaline phosphatase (PLAP) is initially synthesized as a precursor (proPLAP) with a C-terminal extension. We constructed a recombinant cDNA which encodes a chimeric protein (alpha GL-PLAP)...

Carbohydrate structures of the third component of rat complement. Presence of both high-mannose and complex type oligosaccharide chains.

Miki, K, Ogata, S, Misumi, Y, Ikehara, Y

We investigated the carbohydrate structure of the third component of complement (C3) newly synthesized by cultured rat hepatocytes. When the cells were incubated with [3H]mannose, [3H]galactose or...

Primary structure of rat liver alkaline phosphatase deduced from its cDNA.

Misumi, Y, Tashiro, K, Hattori, M, Sakaki, Y, Ikehara, Y

Rat liver alkaline phosphatase (ALP) was markedly induced by treatment of rats by bile-duct ligation and colchicine injection. Taking this advantage for enrichment of ALP mRNA, we constructed a...

Cloning, structure and expression of cDNA for mouse contrapsin and a related protein.

Ohkubo, K, Ogata, S, Misumi, Y, Takami, N, Sinohara, H, Ikehara, Y

A cDNA clone (lambda MC-2) for contrapsin, a serine-proteinase inhibitor, was isolated from a lambda ZAP mouse liver cDNA library. The 1.6 kb cDNA insert of lambda MC-2 contained an open reading...

A new inositol 1,4,5-trisphosphate binding protein similar to phospholipase C-delta 1.

Kanematsu, T, Misumi, Y, Watanabe, Y, Ozaki, S, Koga, T, Iwanaga, S, ...

We have reported that two inositol 1,4,5-trisphosphate binding proteins, with molecular masses of 85 and 130 kDa, were purified from rat brain; the former protein was found to be the delta...

Bip/GRP78 but not calnexin associates with a precursor of glycosylphosphatidylinositol-anchored protein.

Oda, K, Wada, I, Takami, N, Fujiwara, T, Misumi, Y, Ikehara, Y

When fused in-frame with a C-terminal propeptide of placental alkaline phosphatase (PLAP), rat alpha 2u-globulin (alpha GL), a nonglycosylated secretory protein, was expressed on the cell surface as...

Localization of a high-affinity inositol 1,4,5-trisphosphate/inositol 1,4,5,6-tetrakisphosphate binding domain to the pleckstrin homology module of a new 130 kDa protein: characterization of the determinants of structural specificity.

Takeuchi, H, Kanematsu, T, Misumi, Y, Yaakob, H B, Yagisawa, H, Ikehara, Y, ...

We have previously identified a novel 130 kDa protein (p130) which binds Ins(1,4,5)P3 and shares 38% sequence identity with phospholipase C-delta 1 [Kanematsu, Misumi, Watanabe, Ozaki, Koga, Iwanaga,...

Ca2+-dependent interaction of the growth-associated protein GAP-43 with the synaptic core complex.

Haruta, T, Takami, N, Ohmura, M, Misumi, Y, Ikehara, Y

The synaptic vesicle exocytosis occurs by a highly regulated mechanism: syntaxin and 25 kDa synaptosome-associated protein (SNAP-25) are assembled with vesicle-associated membrane protein (VAMP) to...

Intracellular cleavage of glycosylphosphatidylinositol by phospholipase D induces activation of protein kinase Calpha.

Tsujioka, H, Takami, N, Misumi, Y, Ikehara, Y

Many proteins are anchored to the cell membrane by glycosylphosphatidylinositol (GPI). One of the functions proposed for the GPI anchor is as a possible mediator in signal transduction through its...

Nuclear factors interacting with an interleukin-6 responsive element of rat alpha 2-macroglobulin gene.

Ito, T, Tanahashi, H, Misumi, Y, Sakaki, Y

During acute inflammation, a group of liver-derived plasma proteins, acute phase proteins (APPs), increase in concentration. Interleukin-6 (IL-6) is responsible for this increase via the induction of...

Conversion of secretory proteins into membrane proteins by fusing with a glycosylphosphatidylinositol anchor signal of alkaline phosphatase.

Oda, K, Cheng, J, Saku, T, Takami, N, Sohda, M, Misumi, Y, ...

Placental alkaline phosphatase (PLAP) is initially synthesized as a precursor (proPLAP) with a C-terminal extension. We constructed a recombinant cDNA which encodes a chimeric protein (alpha GL-PLAP)...

Carbohydrate structures of the third component of rat complement. Presence of both high-mannose and complex type oligosaccharide chains.

Miki, K, Ogata, S, Misumi, Y, Ikehara, Y

We investigated the carbohydrate structure of the third component of complement (C3) newly synthesized by cultured rat hepatocytes. When the cells were incubated with [3H]mannose, [3H]galactose or...

Primary structure of rat liver alkaline phosphatase deduced from its cDNA.

Misumi, Y, Tashiro, K, Hattori, M, Sakaki, Y, Ikehara, Y

Rat liver alkaline phosphatase (ALP) was markedly induced by treatment of rats by bile-duct ligation and colchicine injection. Taking this advantage for enrichment of ALP mRNA, we constructed a...

Cloning, structure and expression of cDNA for mouse contrapsin and a related protein.

Ohkubo, K, Ogata, S, Misumi, Y, Takami, N, Sinohara, H, Ikehara, Y

A cDNA clone (lambda MC-2) for contrapsin, a serine-proteinase inhibitor, was isolated from a lambda ZAP mouse liver cDNA library. The 1.6 kb cDNA insert of lambda MC-2 contained an open reading...

A new inositol 1,4,5-trisphosphate binding protein similar to phospholipase C-delta 1.

Kanematsu, T, Misumi, Y, Watanabe, Y, Ozaki, S, Koga, T, Iwanaga, S, ...

We have reported that two inositol 1,4,5-trisphosphate binding proteins, with molecular masses of 85 and 130 kDa, were purified from rat brain; the former protein was found to be the delta...

Bip/GRP78 but not calnexin associates with a precursor of glycosylphosphatidylinositol-anchored protein.

Oda, K, Wada, I, Takami, N, Fujiwara, T, Misumi, Y, Ikehara, Y

When fused in-frame with a C-terminal propeptide of placental alkaline phosphatase (PLAP), rat alpha 2u-globulin (alpha GL), a nonglycosylated secretory protein, was expressed on the cell surface as...

Localization of a high-affinity inositol 1,4,5-trisphosphate/inositol 1,4,5,6-tetrakisphosphate binding domain to the pleckstrin homology module of a new 130 kDa protein: characterization of the determinants of structural specificity.

Takeuchi, H, Kanematsu, T, Misumi, Y, Yaakob, H B, Yagisawa, H, Ikehara, Y, ...

We have previously identified a novel 130 kDa protein (p130) which binds Ins(1,4,5)P3 and shares 38% sequence identity with phospholipase C-delta 1 [Kanematsu, Misumi, Watanabe, Ozaki, Koga, Iwanaga,...

Ca2+-dependent interaction of the growth-associated protein GAP-43 with the synaptic core complex.

Haruta, T, Takami, N, Ohmura, M, Misumi, Y, Ikehara, Y

The synaptic vesicle exocytosis occurs by a highly regulated mechanism: syntaxin and 25 kDa synaptosome-associated protein (SNAP-25) are assembled with vesicle-associated membrane protein (VAMP) to...

Intracellular cleavage of glycosylphosphatidylinositol by phospholipase D induces activation of protein kinase Calpha.

Tsujioka, H, Takami, N, Misumi, Y, Ikehara, Y

Many proteins are anchored to the cell membrane by glycosylphosphatidylinositol (GPI). One of the functions proposed for the GPI anchor is as a possible mediator in signal transduction through its...