A limit for the mu -> e gamma decay from the MEG experiment (2009)
Adam, MEG Collaboration: J., Bai, X., Baldini, A., Baracchini, E., Barchiesi, A., Bemporad, C., ...
A search for the decay mu -> e gamma, performed at PSI and based on data from the initial three months of operation of the MEG experiment, yields an upper limit BR(mu -> e gamma) < 3.0 x 10**-11 (90%...
Architecture compliance checking at run-time (2009)
Ganesan, D., Keuler, T., Nishimura, Y.
In this paper, we report on our experiences with architecture compliance checking the process of checking whether the planned or specified software architecture is obeyed by the running system of an...
Architecture compliance checking at run-time (2009)
Ganesan, D., Keuler, T., Nishimura, Y.
In this paper, we report on our experiences with architecture compliance checking - the process of checking whether the planned or specified software architecture is obeyed by the running system - of...
Z. Lin, L. Chen, I. Holod, Y. Nishimura, H. Qu, S. Ethier, ...
This paper reports progress on gyrokinetic particle simulation of turbulence in fusion plasmas including: (1) Electron transport driven by short wavelength trapped electron mode turbulence; (2)...
The first linear global electromagnetic gyrokinetic particle simulation on the excitation of toroidicity induced Alfven eigenmode (TAE) by energetic particles is reported. With an increase in the...
Architecture compliance checking at runtime: An industry experience report (2008)
Ganesan, D., Keuler, T., Nishimura, Y.
In this paper, we report on our experiences we made with architecture compliance checking at run-time. To that end, we constructed hierarchical colored Petri nets (CP-nets), using existing general...
TIME-RESOLVED FOURIER TRANSFORM INFRARED EMISSION SPECTROSCOPY OF LASER ABLATION PRODUCTS (2008)
Kawaguchi, K., Sanechika, N., Nishimura, Y., Fujimori, R., Oka, T. N., Hirahara, Y., ...
K. Kawaguchi, O. Baskakov, Y. Hosaki, Y. Hama, and C. Kugimiya, J. Chem. Phys. LettersG. Nave, S. Johansson, R. C. M. Learner, A. P. Thorne, and J. W. Brault, Astrophy. J. Suppl. Ser.
Architecture compliance checking at runtime: An industry experience report (2008)
Ganesan, D., Keuler, T., Nishimura, Y.
In this paper, we report on our experiences we made with architecture compliance checking at run-time. To that end, we constructed hierarchical colored Petri nets (CP-nets), using existing general...
Biokinetics and dose estimation of 65Zn in the salivary gland and male reproductive organs (2007)
Matsumoto, M., Homma-Takeda, S., Nishimura, Y.
ICRP is revising its recommendations for radiological protection and has added salivary and secretory glands as new target organs. However, little information is available on the distributions of...
Up-regulation of adipogenin, an adipocyte plasma transmembrane protein, during adipogenesis (2005)
Hong, YH, Hishikawa, D, Miyahara, H, Tsuzuki, H, Nishimura, Y, Gotoh, C, ...
The original publication is available at www.springerlink.com.
Overview of ASDEX Upgrade results-development of integrated operating scenarios for ITER (2005)
Günter,S., Angioni,C., Apostoliceanu,M., Atanasiu,C., Balden,M., Becker,G., ...
This article based on the 2004 Fusion Energy Conference contribution (Vilamoura, Portugal, 1-6 November 2004)
Overview of ASDEX Upgrade Results (2005)
Günter,S., Angioni,C., Apostoliceanu,M., Atanasiu,C., Balden,M., Becker,G., ...
Overview of ASDEX Upgrade results-development of integrated operating scenarios for ITER (2005)
Günter, S., Angioni, C., Apostoliceanu, M., Atanasiu, C., Balden, M., Becker, G., ...
This article based on the 2004 Fusion Energy Conference contribution (Vilamoura, Portugal, 1-6 November 2004)
Overview of ASDEX Upgrade Results (2005)
Günter, S., Angioni, C., Apostoliceanu, M., Atanasiu, C., Balden, M., Becker, G., ...
Overview of ASDEX Upgrade results - development of integrated operating scenarios for ITER (2005)
GUNTER, S, ANGIONI, C, APOSTOLICEANU, M, ATANASIU, C, BALDEN, M, BECKER, G, ...
Porphyrin and fullerene-based artificial photosynthetic materials for photovoltaics (2004)
Imahori, H, Kashiwagi, Y, Hasobe, T, Kimura, M, Hanada, T, Nishimura, Y, ...
Imahori, H, Kimura, M, Hosomizu, K, Sato, T, Ahn, TK, Kim, SK, ...
Imahori, H, Hosomizu, K, Mori, Y, Sato, T, Ahn, TK, Kim, SK, ...
Further developments of the edge transport simulation package, SOLPS (2003)
Coster,D. P., Bonnin,X., Braams,B., Bürbaumer,H., Kaveeva,E., ...
The development of the SOLPS suite of codes (B2-Eirene + others) in the last two years is covered. Important issues are: the determination of the anomalous radial transport directly from the...
Overview of ASDEX Upgrade results (2003)
Zohm,H., Angioni,C., Arslanbekov,R., Atanasiu,C., Becker,G., Becker,W., ...
Recent results from the ASDEX Upgrade experimental campaigns 2001 and 2002 are presented. An improved understanding of energy and particle transport emerges in terms of a 'critical gradient' model...
Further developments of the edge transport simulation package, SOLPS (2003)
Coster, D. P., Bonnin, X., Braams, B., Bürbaumer, H., Kaveeva, E., ...
The development of the SOLPS suite of codes (B2-Eirene + others) in the last two years is covered. Important issues are: the determination of the anomalous radial transport directly from the...
Overview of ASDEX Upgrade results (2003)
Zohm, H., Angioni, C., Arslanbekov, R., Atanasiu, C., Becker, G., Becker, W., ...
Recent results from the ASDEX Upgrade experimental campaigns 2001 and 2002 are presented. An improved understanding of energy and particle transport emerges in terms of a 'critical gradient' model...
Yamada, H, Imahori, H, Nishimura, Y, Yamazaki, I, Ahn, TK, Kim, SK, ...
Hasobe, T, Imahori, H, Ohkubo, K, Yamada, H, Sato, T, Nishimura, Y, ...
Overview of ASDEX upgrade results (2003)
Zohm, H., Angioni, C., Arslanbekov, R., Atanasiu, C., Becker, G., Becker, W., ...
Recent results from the ASDEX Upgrade experimental campaigns 2001 and 2002 are presented. An improved understanding of energy and particle transport emerges in terms of a 'critical gradient' model...
Biokinetics of radiotellurium in rats (2003)
Nishimura, Y., K. Sahoo, S., Homma-Takeda, S., Watanabe, Y., Inaba, J.
Radiotellurium is present in the environment primarily due to its release during nuclear reactor accidents. Little is known of tellurium metabolism in juveniles, although the element is relatively...
Tokamak edge model validation and improvement (2002)
Coster,D. P., Kim,J. W., Nishimura,Y., Schneider,R., Bonnin,X., Rozhansky,V., ...
Because of the complexity of the physics in the edge of divertor tokamaks, extrapolation from present-day machines to future reactor or reactor-type devices is done using two- dimensional-edge codes....
Coupling of perpendicular transport in turbulence and divertor codes (2002)
Nishimura,Y., Coster,D. P., Kim,J. W., Scott,B. D.
Edge plasma transport in ASDEX Upgrade is studied employing both turbulence and divertor transport codes. The two codes are coupled. The turbulence code is applied to the inner region of the divertor...
Tokamak edge model validation and improvement (2002)
Coster, D. P., Kim, J. W., Nishimura, Y., Schneider, R., Bonnin, X., Rozhansky, V., ...
Because of the complexity of the physics in the edge of divertor tokamaks, extrapolation from present-day machines to future reactor or reactor-type devices is done using two- dimensional-edge codes....
Coupling of perpendicular transport in turbulence and divertor codes (2002)
Nishimura, Y., Coster, D. P., Kim, J. W., Scott, B. D.
Edge plasma transport in ASDEX Upgrade is studied employing both turbulence and divertor transport codes. The two codes are coupled. The turbulence code is applied to the inner region of the divertor...
Nishimura, Y, ...
OBJECTIVE: The No-React process for biomaterials was suggested to prevent calcification and degeneration. We examined in vivo in a chronic sheep model the performance of a Biocor bovine internal...
Development of an artificial dermis preparation capable of silver sulfadiazine release (2001)
Kawai, K, Suzuki, S, Tabata, Y, Taira, T, Ikada, Y, Nishimura, Y
Nishimura, Y, Jashari, R, Racz, R, Leunens, V H
BACKGROUND: The ICS-Supracor (Abiomed, Danvers, MA) is a preshaped ascending aorta balloon pump. We compared the effects of this catheter with the classical descending intraaortic balloon pump...
The intra-aortic cannula pump: A novel assist device for the acutely failing heart (1999)
Porat, E, Nishimura, Y, Ozaki, S, Racz, R, ...
OBJECTIVE: The intra-aortic cannula pump is a catheter pump designed to support the acutely failing heart. It expels blood from the left ventricle into the ascending aorta in a pulsatile flow...
Chronic heart failure model induced by coronary embolization in sheep (1999)
Perek, B, Dispersyn, G, Nishimura, Y, ...
OBJECTIVE: To create a model of chronic heart failure in a large animal. METHODS: Heart failure was induced in sheep by single intracoronary injection of polymer macrobeads, which were administered...
Onset of high-n ballooning modes during tokamak sawtooth crashes (1999)
Nishimura, Y., Callen, J.D., Hegna, C.C.
This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying...
Circulatory support during minimally invasive coronary surgery (1998)
Department of Cardiac Surgery, University of Leuven, Belgium.
Siess, T, Nishimura, Y, Racz, R, Reul, H, Rau, G, ...
The purpose of this study was to test the pump performance of a miniaturized, newly developed, implantable rotary blood pump (the diagonal pump). In a series of six sheep, the pump was interposed in...
Tearing mode analysis in tokamaks, revisited (1998)
Nishimura, Y., Callen, J.D., Hegna, C.C.
This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying...
Biokinetics and Dose Estimation of Radiocarbon in Rats (1998)
Takeda, H., Fuma, S., Miyamoto, K., Nishimura, Y., Inaba, J.
The biokinetics of 14C in rats ingested in the form of organic compounds (amino acid, fatty acid, monosaccharide and nucleoside), or as an inorganic compound (bicarbonate), were examined and the...
Placental Transfer of 110Agm in Rats (1998)
Nishimura, Y., Takeda, H., Watanabe, Y., Yukawa, M., Inaba, J., Sato, I., ...
Wistar strain pregnant rats were used to determine the uptake of 110Agm by the conceptus in relation to its gestational stages, measuring retention in the placenta, fetal membranes and fetus. The...
Triple strategy to improve early graft function after heart transplantation (1997)
UZ Gasthuisberg, Leuven, Belgium.
Organ perfusion with Hemopump device assistance with and without intraaortic balloon pumping (1997)
Nishimura, Y, Racz, R, Jashari, R
OBJECTIVE: Our objective was to analyze the potential advantage of combining an intraaortic balloon pump with a transthoracic Hemopump device (Medtronic, Inc., Minneapolis, Minn.) (Nimbus Medical,...
Acute-pancreatitis after orthotopic liver transplantation (1997)
Gunson, B, Nishimura, Y, Mirza, D F, Patapis, P, ...
Liver and Hepatobiliary Unit, Queen Elizabeth University Hospital, Edgbaston, Birmingham, UK.
Wakitani, S, Murata, N, Toda, Y, Ogawa, R, Kaneshige, T, Nishimura, Y, ...
Oda, M, Furukawa, K, Ogata, K, Sarai, A, Ishii, S, Nishimura, Y, ...
Clinical usefulness of determining the rate of thermal clearance within heated tumors (1996)
Masunaga, S, Ono, K, Mitsumori, M, Nishimura, Y, Hiraoka, M, Akuta, K, ...
Takeda, H., Nishimura, Y., Inaba, J.
The transfer of tritium through the placenta or milk was investigated to estimate the radiation dose to the fetus and newborn. Female rats at gestational stages or after delivery were exposed to...
Effect of Natural Chelating Agents on the Intestinal Absorption of Radiostrontium in Rats (1994)
Nishimura, Y., Kakuta, I., Takeda, H., Inaba, J., Imai, K., Watari, K., ...
Chitin is a cellulose-like biopolymer distributed widely in nature, especially in crustaceans, insects, fungi and yeast. Its derivative, chitosan is known to be a natural chelating agent. The purpose...
Placental Transfer of Cerium in the Rat with Special Reference to Route of Administration (1992)
Inaba, J., Nishimura, Y., Takeda, H., Takahashi, S.
The transfer of radiocerium to the fetus in the rat was studied to provide quantitative information for the assessment of radiation doses to members of the public in connection with environmental...
Optical rotatory properties of stereoregular asymmetric polyamides (1969)
Overberger, C. G., Montaudo, G., Nishimura, Y., Šebenda, Jan, Veneski, R. A.
No Abstract.
Overview of ASDEX Upgrade Results
Günter,S., Angioni,C., Apostoliceanu,M., Atanasiu,C., Balden,M., Becker,G., ...
Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.
Hanabuchi, S, Koyanagi, M, Kawasaki, A, Shinohara, N, Matsuzawa, A, Nishimura, Y, ...
To investigate the mechanisms of T-cell-mediated cytotoxicity, we estimated the involvement of apoptosis-inducing Fas molecule on the target cells and its ligand on the effector cells. When...
Tanikawa, J, Yasukawa, T, Enari, M, Ogata, K, Nishimura, Y, Ishii, S, ...
The DNA-binding domain of c-Myb consists of three homologous tandem repeats of 52 amino acids. The structure of the third (C-terminal) repeat obtained by NMR analysis has a conformation related to...
Ogata, K, Hojo, H, Aimoto, S, Nakai, T, Nakamura, H, Sarai, A, ...
The DNA-binding domain of the c-myb protooncogene product consists of three imperfect tandem repeats of 51 or 52 amino acids, each of which contains three conserved tryptophans, spaced 18 or 19 amino...
Nojiri, H., Sugimori, M., Yamane, H., Nishimura, Y., Yamada, A., Shibuya, N., ...
It has been suggested that jasmonic acid (JA) could be an integral part of a general signal transduction system regulating inducible defense genes in plants. It was reported that treatment with an...
Nakakuma, H, Hidaka, M, Nagakura, S, Nishimura, Y, Iwamoto, N, Horikawa, K, ...
Paroxysmal nocturnal hemoglobinuria (PNH) erythrocytes lack complement regulatory membrane proteins and are susceptible to complement. Although the critical role of complement in intravascular...
Esaki, Y, Fukui, Y, Sudo, T, Yamamoto, K, Inamitsu, T, Nishimura, Y, ...
Antigenicity of peptic extract from type 12 group A streptococci (PEAST12) for T cells was examined in major histocompatibility complex (MHC) class II transgenic mice. PEAST12 was mitogenic for...
Tsuchimoto, S, Nishimura, Y, Ohtsubo, E
We constructed plasmids carrying heat-inducible pemI and pemK genes, which were fused with the collagen-lacZ sequence in frame. The PemK-collagen-LacZ (PemK*) protein produced from the fusion gene...
Masuda, Y, Miyakawa, K, Nishimura, Y, Ohtsubo, E
The pem locus is responsible for stable maintenance of plasmid R100 and consists of two genes, pemI and pemK. The pemK gene product is a growth inhibitor, while the pemI gene product is a suppressor...
Hara, H, Yamamoto, Y, Higashitani, A, Suzuki, H, Nishimura, Y
The prc gene, which is involved in cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 (PBP 3) of Escherichia coli, was cloned and mapped at 40.4 min on the...
Construction of an ordered cosmid collection of the Escherichia coli K-12 W3110 chromosome.
Tabata, S, Higashitani, A, Takanami, M, Akiyama, K, Kohara, Y, Nishimura, Y, ...
A cosmid library of the Escherichia coli K-12 W3110 chromosome was constructed in which clones were assigned to locations on the chromosome map by hybridization and genetic marker complementation...
Fujisaki, S, Nishino, T, Katsuki, H, Hara, H, Nishimura, Y, Hirota, Y
The screening of a collection of highly mutagenized strains of Escherichia coli for defects in isoprenoid synthesis led to the isolation of a mutant that had temperature-sensitive farnesyl...
Hara, H, Nishimura, Y, Kato, J, Suzuki, H, Nagasawa, H, Suzuki, A, ...
The processing of Escherichia coli penicillin-binding protein 3 (PBP 3) was investigated by gene manipulation for producing hybrid and truncated PBP 3 molecules. The hybrid PBP 3 was processed when...
Kato, J, Nishimura, Y, Yamada, M, Suzuki, H, Hirota, Y
A new mutation, parC, causing abnormal chromosome segregation was identified in two thermosensitive mutants of Escherichia coli. The thermosensitive growth of the mutants was corrected by pLC4-14 in...
Amino acid replacement in a mutant lipoprotein of the Escherichia coli outer membrane.
Inouye, S, Lee, N, Inouye, M, Wu, H C, Suzuki, H, Nishimura, Y, ...
The primary structure of a mutant lipoprotein of the outer membrane of Escherichia coli was investigated. This mutant was previously described as a mutant that forms a dimer of the lipoprotein by an...
Suzuki, H, Nishimura, Y, Iketani, H, Campisi, J, Hirashima, A
A novel mutation which caused a structural change in a lipoprotein in the outer-membrane has been found in Escherichia coli K-12. The lipoprotein of the wild-type strain is known to have a peculiar...
Novel gelatin particle agglutination test for serodiagnosis of leprosy in the field.
Izumi, S, Fujiwara, T, Ikeda, M, Nishimura, Y, Sugiyama, K, Kawatsu, K
We developed a novel gelatin particle agglutination test (MLPA) for the serodiagnosis of leprosy; this test is especially useful for clinical practice and epidemiological surveys of leprosy in...
Oshita, M, Takei, Y, Kawano, S, Yoshihara, H, Hijioka, T, Fukui, H, ...
This study was designed to investigate the mechanism for ethanol-induced hepatic vasoconstriction in isolated perfused rat liver. Upon initiation of ethanol infusion into the portal vein at...
Nishimura, Y, Suzuki, H, Hirota, Y, Park, J T
A mutant of Escherichia coli defective in penicillin-binding protein 5 activity was isolated. The mutation (pfv) was shown to be located at 14.0 min on the E. coli chromosome map. Loss of...
Hirao, I, Kawai, G, Yoshizawa, S, Nishimura, Y, Ishido, Y, Watanabe, K, ...
The three-dimensional structure of a short DNA fragment, d(GCGAAGC) exhibiting an extraordinarily stable hairpin structure was determined by nuclear magnetic resonance spectroscopy. Two possible...
Hirao, I, Nishimura, Y, Naraoka, T, Watanabe, K, Arata, Y, Miura, K
Short single-stranded DNA fragments carrying a GCGAAAGC sequence were found to move unexpectedly faster than other fragments of the same length in electrophoresis on a polyacrylamide gel containing a...
Sternglanz, R, DiNardo, S, Voelkel, K A, Nishimura, Y, Hirota, Y, Becherer, K, ...
Mutations in top, the structural gene for Escherichia coli DNA topoisomerase I, have been identified and mapped at 28 min on the chromosome, near cysB. Strains carrying deletions of the top gene are...
Nishimura, Y, Tsuboi, M, Sato, T
Raman spectra of nine crystals of known structures which involve guanosine moieties with various conformations have been observed. It has been established that a guanosine residue with the...
On the base-stacking in the 5'-terminal cap structure of mRNA: a fluorescence study.
Nishimura, Y, Takahashi, S, Yamamoto, T, Tsuboi, M, Hattori, M, Miura, K, ...
The fluorescence at 370 nm of the 7-methylguanosine residue (m7G) is found to be quenched when the base residue is involved in a stacking interaction with the adenosine residue in the cap structure...
Nishimura, Y, Tsuboi, M, Nakano, T, Higuchi, S, Sato, T, Shida, T, ...
Observations of Raman spectra of various nucleic acids indicate that the guanine ring breathing frequency is sensitive to the internal rotation angle around the glycosidic bond and to the...
Hirao, I, Nishimura, Y, Tagawa, Y, Watanabe, K, Miura, K
A small DNA fragment having a characteristic sequence d(GCGAAAGC) has been shown to form an extraordinarily stable mini-hairpin structure and to have an unusually rapid mobility in polyacrylamide gel...
The structure of nucleosome core particles as revealed by difference Raman spectroscopy.
Hayashi, H, Nishimura, Y, Katahira, M, Tsuboi, M
Raman spectra have been observed of nucleosome core particles (I) prepared from chicken erythrocyte chromatin, its isolated 146 bp DNA (II), and its isolated histone octamer (H2A+H2B+H3+H4)2 (III)....
Nishimura, Y, Torigoe, C, Tsuboi, M
Raman spectra of poly(dG).poly(dC) have been observed in aqueous solutions at various ionic strengths, [NaCl] = 0.03 to 4 M, and at different temperatures, 10 to 60 degrees C. At 30 degrees C, and at...
Noguchi, S, Yamaizumi, Z, Ohgi, T, Goto, T, Nishimura, Y, Hirota, Y, ...
One of the E. coli mutants selected for deficiency of modified nucleoside Q was found to contain an analogue of Q and normal guanosine in place of Q. The analogue of Q, designated as preQo, was...
Tamura, T, Suzuki, H, Nishimura, Y, Mizoguchi, J, Hirota, Y
Multiple mutants of Escherichia coli defective in penicillin-binding proteins (PBPs) were constructed, and into these strains Co1E1 plasmids carrying the genes for PBP-1a, -1b, or -3 were introduced....
Nishimura, Y, Rosenfeld, M G, Kreibich, G, Gubler, U, Sabatini, D D, Adesnik, M, ...
We have selected the rat preputial gland beta-glucuronidase as a model protein to study the sorting of newly synthesized lysosomal hydrolases to the lysosome. The complete coding sequence of...
Matsuhashi, M, Maruyama, I N, Takagaki, Y, Tamaki, S, Nishimura, Y, Hirota, Y
A mutant of Escherichia coli that is deficient in D-alanine carboxypeptidase IA has been isolated. The enzyme is membrane bound and moderately sensitive to penicillin. It catalyzes in vitro both...
Suzuki, H, Nishimura, Y, Hirota, Y
A series of mutants defective in penicillin-binding components (or protein) (PBCs) was isolated from a collection of thermosensitive mutants of Escherichia coli. The mutants included mutations for...
Hirota, Y, Suzuki, H, Nishimura, Y, Yasuda, S
A mutant of E. coli lacking a specific outer membrane lipoprotein was found. Both the free and the bound form have been lost in this mutant. No material that cross-reacted with antiserum against...
Matsuhashi, M, Takagaki, Y, Maruyama, I N, Tamaki, S, Nishimura, Y, Suzuki, H, ...
Mutants of Escherichia coli lacking in the highly penicillin-sensitive enzyme activities of D-carboxy-peptidase, transpeptidase, and endopeptidase, and with the concomitant absence of...
Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5.
Bierer, B E, Nishimura, Y, Burakoff, S J, Smith, B R
Although the CD5 (T1) antigen was initially described as a pan-T cell membrane glycoprotein, we report that 14 of 40 normal individuals were found to have 5% or greater of their blood mononuclear...
Yamaguchi, K, Matutes, E, Kiyokawa, T, Nishimura, Y, Ishii, T, Takatsuki, K, ...
Serum antibodies against human T cell leukaemia virus type I (HTLV-I) were investigated in 12 patients by four methods: indirect immunoperoxidase staining, indirect immunofluorescence, enzyme linked...
Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.
Hanabuchi, S, Koyanagi, M, Kawasaki, A, Shinohara, N, Matsuzawa, A, Nishimura, Y, ...
To investigate the mechanisms of T-cell-mediated cytotoxicity, we estimated the involvement of apoptosis-inducing Fas molecule on the target cells and its ligand on the effector cells. When...
Tanikawa, J, Yasukawa, T, Enari, M, Ogata, K, Nishimura, Y, Ishii, S, ...
The DNA-binding domain of c-Myb consists of three homologous tandem repeats of 52 amino acids. The structure of the third (C-terminal) repeat obtained by NMR analysis has a conformation related to...
Ogata, K, Hojo, H, Aimoto, S, Nakai, T, Nakamura, H, Sarai, A, ...
The DNA-binding domain of the c-myb protooncogene product consists of three imperfect tandem repeats of 51 or 52 amino acids, each of which contains three conserved tryptophans, spaced 18 or 19 amino...
Nojiri, H., Sugimori, M., Yamane, H., Nishimura, Y., Yamada, A., Shibuya, N., ...
It has been suggested that jasmonic acid (JA) could be an integral part of a general signal transduction system regulating inducible defense genes in plants. It was reported that treatment with an...
Nakakuma, H, Hidaka, M, Nagakura, S, Nishimura, Y, Iwamoto, N, Horikawa, K, ...
Paroxysmal nocturnal hemoglobinuria (PNH) erythrocytes lack complement regulatory membrane proteins and are susceptible to complement. Although the critical role of complement in intravascular...
Esaki, Y, Fukui, Y, Sudo, T, Yamamoto, K, Inamitsu, T, Nishimura, Y, ...
Antigenicity of peptic extract from type 12 group A streptococci (PEAST12) for T cells was examined in major histocompatibility complex (MHC) class II transgenic mice. PEAST12 was mitogenic for...
Tsuchimoto, S, Nishimura, Y, Ohtsubo, E
We constructed plasmids carrying heat-inducible pemI and pemK genes, which were fused with the collagen-lacZ sequence in frame. The PemK-collagen-LacZ (PemK*) protein produced from the fusion gene...
Masuda, Y, Miyakawa, K, Nishimura, Y, Ohtsubo, E
The pem locus is responsible for stable maintenance of plasmid R100 and consists of two genes, pemI and pemK. The pemK gene product is a growth inhibitor, while the pemI gene product is a suppressor...
Hara, H, Yamamoto, Y, Higashitani, A, Suzuki, H, Nishimura, Y
The prc gene, which is involved in cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 (PBP 3) of Escherichia coli, was cloned and mapped at 40.4 min on the...
Construction of an ordered cosmid collection of the Escherichia coli K-12 W3110 chromosome.
Tabata, S, Higashitani, A, Takanami, M, Akiyama, K, Kohara, Y, Nishimura, Y, ...
A cosmid library of the Escherichia coli K-12 W3110 chromosome was constructed in which clones were assigned to locations on the chromosome map by hybridization and genetic marker complementation...
Fujisaki, S, Nishino, T, Katsuki, H, Hara, H, Nishimura, Y, Hirota, Y
The screening of a collection of highly mutagenized strains of Escherichia coli for defects in isoprenoid synthesis led to the isolation of a mutant that had temperature-sensitive farnesyl...
Hara, H, Nishimura, Y, Kato, J, Suzuki, H, Nagasawa, H, Suzuki, A, ...
The processing of Escherichia coli penicillin-binding protein 3 (PBP 3) was investigated by gene manipulation for producing hybrid and truncated PBP 3 molecules. The hybrid PBP 3 was processed when...
Kato, J, Nishimura, Y, Yamada, M, Suzuki, H, Hirota, Y
A new mutation, parC, causing abnormal chromosome segregation was identified in two thermosensitive mutants of Escherichia coli. The thermosensitive growth of the mutants was corrected by pLC4-14 in...
Amino acid replacement in a mutant lipoprotein of the Escherichia coli outer membrane.
Inouye, S, Lee, N, Inouye, M, Wu, H C, Suzuki, H, Nishimura, Y, ...
The primary structure of a mutant lipoprotein of the outer membrane of Escherichia coli was investigated. This mutant was previously described as a mutant that forms a dimer of the lipoprotein by an...
Suzuki, H, Nishimura, Y, Iketani, H, Campisi, J, Hirashima, A
A novel mutation which caused a structural change in a lipoprotein in the outer-membrane has been found in Escherichia coli K-12. The lipoprotein of the wild-type strain is known to have a peculiar...
Novel gelatin particle agglutination test for serodiagnosis of leprosy in the field.
Izumi, S, Fujiwara, T, Ikeda, M, Nishimura, Y, Sugiyama, K, Kawatsu, K
We developed a novel gelatin particle agglutination test (MLPA) for the serodiagnosis of leprosy; this test is especially useful for clinical practice and epidemiological surveys of leprosy in...
Oshita, M, Takei, Y, Kawano, S, Yoshihara, H, Hijioka, T, Fukui, H, ...
This study was designed to investigate the mechanism for ethanol-induced hepatic vasoconstriction in isolated perfused rat liver. Upon initiation of ethanol infusion into the portal vein at...
Nishimura, Y, Suzuki, H, Hirota, Y, Park, J T
A mutant of Escherichia coli defective in penicillin-binding protein 5 activity was isolated. The mutation (pfv) was shown to be located at 14.0 min on the E. coli chromosome map. Loss of...
Hirao, I, Kawai, G, Yoshizawa, S, Nishimura, Y, Ishido, Y, Watanabe, K, ...
The three-dimensional structure of a short DNA fragment, d(GCGAAGC) exhibiting an extraordinarily stable hairpin structure was determined by nuclear magnetic resonance spectroscopy. Two possible...
Hirao, I, Nishimura, Y, Naraoka, T, Watanabe, K, Arata, Y, Miura, K
Short single-stranded DNA fragments carrying a GCGAAAGC sequence were found to move unexpectedly faster than other fragments of the same length in electrophoresis on a polyacrylamide gel containing a...
Sternglanz, R, DiNardo, S, Voelkel, K A, Nishimura, Y, Hirota, Y, Becherer, K, ...
Mutations in top, the structural gene for Escherichia coli DNA topoisomerase I, have been identified and mapped at 28 min on the chromosome, near cysB. Strains carrying deletions of the top gene are...
Nishimura, Y, Tsuboi, M, Sato, T
Raman spectra of nine crystals of known structures which involve guanosine moieties with various conformations have been observed. It has been established that a guanosine residue with the...
On the base-stacking in the 5'-terminal cap structure of mRNA: a fluorescence study.
Nishimura, Y, Takahashi, S, Yamamoto, T, Tsuboi, M, Hattori, M, Miura, K, ...
The fluorescence at 370 nm of the 7-methylguanosine residue (m7G) is found to be quenched when the base residue is involved in a stacking interaction with the adenosine residue in the cap structure...
Nishimura, Y, Tsuboi, M, Nakano, T, Higuchi, S, Sato, T, Shida, T, ...
Observations of Raman spectra of various nucleic acids indicate that the guanine ring breathing frequency is sensitive to the internal rotation angle around the glycosidic bond and to the...
Hirao, I, Nishimura, Y, Tagawa, Y, Watanabe, K, Miura, K
A small DNA fragment having a characteristic sequence d(GCGAAAGC) has been shown to form an extraordinarily stable mini-hairpin structure and to have an unusually rapid mobility in polyacrylamide gel...
The structure of nucleosome core particles as revealed by difference Raman spectroscopy.
Hayashi, H, Nishimura, Y, Katahira, M, Tsuboi, M
Raman spectra have been observed of nucleosome core particles (I) prepared from chicken erythrocyte chromatin, its isolated 146 bp DNA (II), and its isolated histone octamer (H2A+H2B+H3+H4)2 (III)....
Nishimura, Y, Torigoe, C, Tsuboi, M
Raman spectra of poly(dG).poly(dC) have been observed in aqueous solutions at various ionic strengths, [NaCl] = 0.03 to 4 M, and at different temperatures, 10 to 60 degrees C. At 30 degrees C, and at...
Noguchi, S, Yamaizumi, Z, Ohgi, T, Goto, T, Nishimura, Y, Hirota, Y, ...
One of the E. coli mutants selected for deficiency of modified nucleoside Q was found to contain an analogue of Q and normal guanosine in place of Q. The analogue of Q, designated as preQo, was...
Tamura, T, Suzuki, H, Nishimura, Y, Mizoguchi, J, Hirota, Y
Multiple mutants of Escherichia coli defective in penicillin-binding proteins (PBPs) were constructed, and into these strains Co1E1 plasmids carrying the genes for PBP-1a, -1b, or -3 were introduced....
Nishimura, Y, Rosenfeld, M G, Kreibich, G, Gubler, U, Sabatini, D D, Adesnik, M, ...
We have selected the rat preputial gland beta-glucuronidase as a model protein to study the sorting of newly synthesized lysosomal hydrolases to the lysosome. The complete coding sequence of...
Matsuhashi, M, Maruyama, I N, Takagaki, Y, Tamaki, S, Nishimura, Y, Hirota, Y
A mutant of Escherichia coli that is deficient in D-alanine carboxypeptidase IA has been isolated. The enzyme is membrane bound and moderately sensitive to penicillin. It catalyzes in vitro both...
Suzuki, H, Nishimura, Y, Hirota, Y
A series of mutants defective in penicillin-binding components (or protein) (PBCs) was isolated from a collection of thermosensitive mutants of Escherichia coli. The mutants included mutations for...
Hirota, Y, Suzuki, H, Nishimura, Y, Yasuda, S
A mutant of E. coli lacking a specific outer membrane lipoprotein was found. Both the free and the bound form have been lost in this mutant. No material that cross-reacted with antiserum against...
Matsuhashi, M, Takagaki, Y, Maruyama, I N, Tamaki, S, Nishimura, Y, Suzuki, H, ...
Mutants of Escherichia coli lacking in the highly penicillin-sensitive enzyme activities of D-carboxy-peptidase, transpeptidase, and endopeptidase, and with the concomitant absence of...
Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5.
Bierer, B E, Nishimura, Y, Burakoff, S J, Smith, B R
Although the CD5 (T1) antigen was initially described as a pan-T cell membrane glycoprotein, we report that 14 of 40 normal individuals were found to have 5% or greater of their blood mononuclear...
Yamaguchi, K, Matutes, E, Kiyokawa, T, Nishimura, Y, Ishii, T, Takatsuki, K, ...
Serum antibodies against human T cell leukaemia virus type I (HTLV-I) were investigated in 12 patients by four methods: indirect immunoperoxidase staining, indirect immunofluorescence, enzyme linked...
Overview of ASDEX Upgrade Results
Günter, S., Angioni, C., Apostoliceanu, M., Atanasiu, C., Balden, M., Becker, G., ...
Murakami, Y, Kong, Y Y, Nishimura, Y, Nomoto, K, Umesue, M, Omoto, K, ...
Anti-T-cell receptor (TCR)alpha beta monoclonal antibody (mAb; H57-597) injection in mice caused cytokine (tumour necrosis factor and interferon-gamma) release and clinical side-effects such as...
HLA-linked immune suppression in humans
Sasazuki, T., Kikuchi, I., Hirayama, K., Matsushita, S., Ohta, N., Nishimura, Y.
There is no doubt that HLA-DR molecules are acting as the products of HLA-linked immune response genes (Ir-genes), because (i) HLA-DR molecules are the restriction elements in the interaction between...
Nishimura, Y, Eto, M, Maeda, T, Hiromatsu, K, Kobayashi, N, Nomoto, K, ...
We compared the effects of in vivo administration of the anti-T-cell receptor (TCR) alpha beta monoclonal antibody (mAb) (H57-597) to those of the anti-CD3 mAb (145-2C11), with or without anti-NK1.1...
Maeda, T, Eto, M, Nishimura, Y, Nomoto, K, Kong, Y Y, Nomoto, K
It has previously been reported that a single i.p. injection of 200 mg/kg cyclophosphamide (CP) 2 days after priming with 10(8) donor spleen cells (SC) leads to donor-specific skin allograft...
Eto, M, Yoshikai, Y, Nishimura, Y, Hiromatsu, K, Maeda, T, Nomoto, K, ...
Anti-CD3 monoclonal antibody (mAb) has been administered in clinical organ transplantation to reverse acute allograft rejection; however, severe immunodeficiency can result from such mAb treatment...
Kawabata, A., Nishimura, Y., Takagi, H.
1. Intraplantar injection of carrageenin into the mouse hind paw produced hyperalgesia when measured by the paw pressure test (Randall & Selitto method). 2. Subcutaneous administration of L-arginine...
1. The 5-hydroxytryptamine (5-HT) induced-contraction in ring preparations of basilar arteries from Wistar-Kyoto rats (WKY) and stroke-prone spontaneously hypertensive rats (SHRSP) was...
Neuropathological studies of the spinal cord in early stage HTLV-I-associated myelopathy (HAM).
Yoshioka, A, Hirose, G, Ueda, Y, Nishimura, Y, Sakai, K
Necropsy findings for a patient with HTLV-I-associated myelopathy (HAM) of 9 months clinical duration are reported. Loss of myelin sheaths and axons together with perivascular lymphocytic...
Cerebrospinal fluid lactate in patients with diabetes mellitus and hypoglycaemic coma.
Yao, H, Sadoshima, S, Nishimura, Y, Fujii, K, Oshima, M, Ishitsuka, T, ...
Cerebrospinal fluid (CSF) lactate and pyruvate concentrations were determined in 20 patients with diabetes mellitus but without disturbance of consciousness and five who recovered from hypoglycaemic...
Mizoguchi, K, Hase, A, Obi, T, Matsuoka, H, Takatsu, M, Nishimura, Y, ...
A patient with a pharyngeal-cervical-brachial variant of Guillain-Barré syndrome had anti-GT1a and anti-GD1a antibodies (IgG) in the serum. The activities of anti-GT1a antibodies were stronger than...
Yanagihara, C, Yasuda, M, Maeda, K, Miyoshi, K, Nishimura, Y
Background: Genetic prion diseases are associated with point or insertional mutations in the PrP gene. The insertional mutations described so far consist of one to nine extra octapeptide repeats,...
Long-term follow up in type A insulin resistant syndrome treated by insulin-like growth factor I.
Ishihama, H, Suzuki, Y, Muramatsu, K, Nagai, M, Kokubo, M, Shiraya, H, ...
Insulin-like growth factor I (IGF-I) is a useful therapeutic agent in insulin resistant diabetes mellitus due to insulin receptor disease because of its hypoglycaemic effects through the IGF-I...
Kondo, A, Isaji, S, Nishimura, Y, Tanaka, T
Monocyte chemoattractant protein‐3 (MCP‐3) is one of the most broadly active chemokines, potentially inducing chemotaxis of all leucocytic cells. In the present study, we examined the regulation...
Combined effects of an angiogenesis inhibitor (TNP-470) and hyperthermia.
Nishimura, Y., Murata, R., Hiraoka, M.
TNP-470, a synthetic analogue of fumagillin first isolated from Aspergillus fumigatus, is known to be a potent anti-angiogenic compound. The combined effects on tumour growth and tumour angiogenesis...
Masunaga, S., Ono, K., Akaboshi, M., Nishimura, Y., Suzuki, M., Kinashi, Y., ...
C3H/He mice bearing SCC VII tumours received 5-bromo-2'-deoxyuridine (BrdU) continuously for 5 days via implanted mini-osmotic pumps in order to label all proliferating (P) cells. The tumours were...
Shibamoto, Y., Ohshio, G., Hosotani, R., Nishimura, Y., Manabe, T., Imamura, M., ...
A fluorinated 2-nitroimidazole radiosensitizer KU-2285 was given before intraoperative radiotherapy (IORT) to 30 patients with unresectable, unresected or macroscopic residual tumours. Twenty-three...
Yamada, M, Kudoh, S, Fukuda, H, Nakagawa, K, Yamamoto, N, Nishimura, Y, ...
Dose-escalation study was performed to evaluate the maximum tolerated dose, recommended dose and toxicity profile of weekly irinotecan with daily carboplatin and concurrent thoracic radiotherapy in...