Y. Patel

Publication List Details

Period

1995 - 2008

Number

41

Co-Authors

Laparoscopic management of an ovarian entopic pregnancy: Case report (2008)

Patel, Y, Wanyonyi, S Z, Rana, FS

No Abstract. East African Medical Journal Vol. 85 (4) 2008: pp. 201-204

Actue puerperal uterine inversion: Case report (2008)

Sequeria, E, Patel, Y

No Abstract. East African Medical Journal Vol. 84 (4) 2007: pp. 194-196

Right ectopic gestation following in vitro fertilisation: case report (2006)

Parkar, RB, Patel, Y

The management of ectopic gestation has in recent years transformed from the normally accepted laparotomy to the laparoscopic approach. The objective of this case report is to describe a rare...

Analyse des potentialités des associations M.O.S thyristors : conception et réalisation d'un Thyristor M.O.S haute tension (1995)

Berriane, R., Patel, Y., Jalade, J.

Nous présentons dans cet article la conception et la réalisation d'un thyristor commandé à la fermeture par une grille M.O.S afin d'étudier et d'analyser les potentialités apportées par...

Analyse des potentialités des associations M.O.S thyristors : conception et réalisation d'un Thyristor M.O.S haute tension (1995)

Berriane, R., Patel, Y., Jalade, J.

Nous présentons dans cet article la conception et la réalisation d'un thyristor commandé à la fermeture par une grille M.O.S afin d'étudier et d'analyser les potentialités apportées par...

Analyse des potentialités des associations M.O.S thyristors : conception et réalisation d'un Thyristor M.O.S haute tension (1995)

Berriane, R., Patel, Y., Jalade, J.

Nous présentons dans cet article la conception et la réalisation d'un thyristor commandé à la fermeture par une grille M.O.S afin d'étudier et d'analyser les potentialités apportées par...

STRUCTURE AND FUNCTION OF 14-3-3 ISOFORMS (1995)

Aitken, A., Patel, Y., Martin, H., Jones, D., Robinson, K., Madrazo, J.

ESMS of 14-3-3 proteins gave results which are in very close agreement to the theoretical values and verified the presence of N-acetylation. Two sets of sheep and chicken brain isoforms differ in...

STRUCTURE AND FUNCTION OF 14-3-3 ISOFORMS (1995)

Aitken, A., Patel, Y., Martin, H., Jones, D., Robinson, K., Madrazo, J.

ESMS of 14-3-3 proteins gave results which are in very close agreement to the theoretical values and verified the presence of N-acetylation. Two sets of sheep and chicken brain isoforms differ in...

Structure and function of 14-3-3 isoforms (1995)

Aitken, A., Patel, Y., Martin, H., Jones, D., Robinson, K., Madrazo, J.

ESMS of 14-3-3 proteins gave results which are in very close agreement to the theoretical values and verified the presence of N-acetylation. Two sets of sheep and chicken brain isoforms differ in...

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.

McCabe, N R, Gill, H J, Espinosa, R, Patel, Y, Harden, A, ...

Recurring chromosomal translocations involving chromosome 11, band q23, have been observed in acute lymphoid leukemias and especially in acute myeloid leukemias. We recently showed that breakpoints...

Restriction endonucleases for pulsed field mapping of bacterial genomes.

McClelland, M, Jones, R, Patel, Y, Nelson, M

Fundamental to many bacterial genome mapping strategies currently under development is the need to cleave the genome into a few large DNA fragments that can be resolved by pulsed field gel...

Cleavage at the twelve-base-pair sequence 5'-TCTAGATCTAGA-3' using M.Xbal (TCTAGm6A) methylation and DpnI (Gm6A/TC) cleavage.

Patel, Y, Van Cott, E, Wilson, G G, McClelland, M

The DNA methylase M.Xbal was isolated from an E. coli recombinant clone. We deduce that the enzyme methylates at the sequence 5'-TCTAGm6A-3'. In combination with the methylation-dependent restriction...

Receptor- and phorbol-ester-mediated redistribution of protein kinase C in human platelets. Evidence that aggregation promotes degradation of protein kinase C.

Wheeler-Jones, C P, Patel, Y, Kakkar, V V, Krishnamurthi, S

Translocation of Ca2+/phospholipid-dependent protein kinase (PKC) activity from cytosolic to membrane fractions was assessed in washed human platelet suspensions. Phorbol myristate acetate (PMA)...

Ca2+ release from platelet intracellular stores by thapsigargin and 2,5-di-(t-butyl)-1,4-benzohydroquinone: relationship to Ca2+ pools and relevance in platelet activation.

Authi, K S, Bokkala, S, Patel, Y, Kakkar, V V, Munkonge, F

The effects of the Ca(2+)-ATPase inhibitors thapsigargin (Tg) and 2,5-di-(t-butyl)-1,4-benzohydroquinone (tBuBHQ) were examined by using Ca(2+)-regulatory systems of platelet mixed membranes,...

Specific binding sites for inositol 1,3,4,5-tetrakisphosphate are located predominantly in the plasma membranes of human platelets.

Cullen, P J, Patel, Y, Kakkar, V V, Irvine, R F, Authi, K S

In the present study we describe the characterization and localization of Ins(1,3,4,5)P4-binding sites in human platelet membranes. Specific binding sites for Ins(1,3,4,5)P4 have been identified on...

Mechanism of inhibition of protein kinase C by 14-3-3 isoforms. 14-3-3 isoforms do not have phospholipase A2 activity.

Robinson, K, Jones, D, Patel, Y, Martin, H, Madrazo, J, Martin, S, ...

The ability of individual members of the 14-3-3 protein family to inhibit protein kinase C (PKC) has been studied by using a synthetic peptide based on the specific 80 kDa substrate for PKC (MARCKS...

Inhibition of agonist-induced platelet aggregation, Ca2+ mobilization and granule secretion by guanosine 5'-[beta-thio]diphosphate and GDP in intact platelets. Evidence for an inhibitory mechanism unrelated to the inhibition of G-protein-GTP interaction.

Krishnamurthi, S, Patel, Y, Kakkar, V V

The effect of guanosine 5'-[beta-thio]diphosphate (GDP[beta S]), reported to be an antagonist of GTP at the G-protein-binding site, on human platelet activation was examined. GDP[beta S] (0.3-3 mM)...

Differential recognition of snake venom proteins expressing specific Arg-Gly-Asp (RGD) sequence motifs by wild-type and variant integrin alphaIIbbeta3: further evidence for distinct sites of RGD ligand recognition exhibiting negative allostery.

Rahman, S, Flynn, G, Aitken, A, Patel, Y, Hussain, F, Lu, X, ...

Several studies have demonstrated that the amino acid residues flanking the Arg-Gly-Asp (RGD) sequence of high-affinity ligands modulate their specificity of interaction with integrin complexes....

Serine protease inhibitors suppress cytochrome c-mediatedcaspase-9 activation and apoptosis during hypoxia-reoxygenation.

Dong, Z, Saikumar, P, Patel, Y, Weinberg, J M, Venkatachalam, M A

We have shown that reoxygenation of hypoxic rat kidney proximaltubule cells leads to apoptosis. This is mediated by translocation ofBax from the cytosol to mitochondria, accompanied by release...

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.

McCabe, N R, Gill, H J, Espinosa, R, Patel, Y, Harden, A, ...

Recurring chromosomal translocations involving chromosome 11, band q23, have been observed in acute lymphoid leukemias and especially in acute myeloid leukemias. We recently showed that breakpoints...

Restriction endonucleases for pulsed field mapping of bacterial genomes.

McClelland, M, Jones, R, Patel, Y, Nelson, M

Fundamental to many bacterial genome mapping strategies currently under development is the need to cleave the genome into a few large DNA fragments that can be resolved by pulsed field gel...

Cleavage at the twelve-base-pair sequence 5'-TCTAGATCTAGA-3' using M.Xbal (TCTAGm6A) methylation and DpnI (Gm6A/TC) cleavage.

Patel, Y, Van Cott, E, Wilson, G G, McClelland, M

The DNA methylase M.Xbal was isolated from an E. coli recombinant clone. We deduce that the enzyme methylates at the sequence 5'-TCTAGm6A-3'. In combination with the methylation-dependent restriction...

Receptor- and phorbol-ester-mediated redistribution of protein kinase C in human platelets. Evidence that aggregation promotes degradation of protein kinase C.

Wheeler-Jones, C P, Patel, Y, Kakkar, V V, Krishnamurthi, S

Translocation of Ca2+/phospholipid-dependent protein kinase (PKC) activity from cytosolic to membrane fractions was assessed in washed human platelet suspensions. Phorbol myristate acetate (PMA)...

Ca2+ release from platelet intracellular stores by thapsigargin and 2,5-di-(t-butyl)-1,4-benzohydroquinone: relationship to Ca2+ pools and relevance in platelet activation.

Authi, K S, Bokkala, S, Patel, Y, Kakkar, V V, Munkonge, F

The effects of the Ca(2+)-ATPase inhibitors thapsigargin (Tg) and 2,5-di-(t-butyl)-1,4-benzohydroquinone (tBuBHQ) were examined by using Ca(2+)-regulatory systems of platelet mixed membranes,...

Specific binding sites for inositol 1,3,4,5-tetrakisphosphate are located predominantly in the plasma membranes of human platelets.

Cullen, P J, Patel, Y, Kakkar, V V, Irvine, R F, Authi, K S

In the present study we describe the characterization and localization of Ins(1,3,4,5)P4-binding sites in human platelet membranes. Specific binding sites for Ins(1,3,4,5)P4 have been identified on...

Mechanism of inhibition of protein kinase C by 14-3-3 isoforms. 14-3-3 isoforms do not have phospholipase A2 activity.

Robinson, K, Jones, D, Patel, Y, Martin, H, Madrazo, J, Martin, S, ...

The ability of individual members of the 14-3-3 protein family to inhibit protein kinase C (PKC) has been studied by using a synthetic peptide based on the specific 80 kDa substrate for PKC (MARCKS...

Inhibition of agonist-induced platelet aggregation, Ca2+ mobilization and granule secretion by guanosine 5'-[beta-thio]diphosphate and GDP in intact platelets. Evidence for an inhibitory mechanism unrelated to the inhibition of G-protein-GTP interaction.

Krishnamurthi, S, Patel, Y, Kakkar, V V

The effect of guanosine 5'-[beta-thio]diphosphate (GDP[beta S]), reported to be an antagonist of GTP at the G-protein-binding site, on human platelet activation was examined. GDP[beta S] (0.3-3 mM)...

Differential recognition of snake venom proteins expressing specific Arg-Gly-Asp (RGD) sequence motifs by wild-type and variant integrin alphaIIbbeta3: further evidence for distinct sites of RGD ligand recognition exhibiting negative allostery.

Rahman, S, Flynn, G, Aitken, A, Patel, Y, Hussain, F, Lu, X, ...

Several studies have demonstrated that the amino acid residues flanking the Arg-Gly-Asp (RGD) sequence of high-affinity ligands modulate their specificity of interaction with integrin complexes....

Serine protease inhibitors suppress cytochrome c-mediatedcaspase-9 activation and apoptosis during hypoxia-reoxygenation.

Dong, Z, Saikumar, P, Patel, Y, Weinberg, J M, Venkatachalam, M A

We have shown that reoxygenation of hypoxic rat kidney proximaltubule cells leads to apoptosis. This is mediated by translocation ofBax from the cytosol to mitochondria, accompanied by release...

Effects of antigen presentation on superantigen-induced apoptosis mediated by Fas/Fas ligand interactions in human T cells.

Boshell, M, McLeod, J, Walker, L, Hall, N, Patel, Y, Sansom, D

Stimulation of T cells with bacterial superantigens has several distinct functional outcomes including proliferation, anergy and apoptosis. At present however, the mechanisms that dictate whether...

Clinical and serological associations with anti-RNA polymerase antibodies in systemic sclerosis

Harvey, G R, Butts, S, Rands, A L, Patel, Y, McHugh, N J

There are three classes of RNA polymerase enzyme (RNAPs I, II and III). In systemic sclerosis (SSc), three main groups of anti-RNAP sera have been characterized by radioimmunoprecipitation...