Y. Ron

A murine model for B-lymphocyte somatic cell gene therapy.

Sutkowski, N, Kuo, M L, Varela-Echavarria, A, Dougherty, J P, Ron, Y

Mature primary B lymphocytes represent a potentially important cellular target for somatic cell gene therapy, which could prove advantageous for the treatment of certain metabolic and immunologic...

Genetic rearrangements occurring during a single cycle of murine leukemia virus vector replication: characterization and implications.

Parthasarathi, S, Varela-Echavarría, A, Ron, Y, Preston, B D, Dougherty, J P

Retroviruses evolve at rapid rates, which is presumably advantageous for responding to selective pressures. Understanding the basic mutational processes involved during retroviral replication is...

Inducible human immunodeficiency virus type 1 packaging cell lines.

Yu, H, Rabson, A B, Kaul, M, Ron, Y, Dougherty, J P

Packaging cell lines are important tools for transferring genes into eukaryotic cells. Human immunodeficiency virus type 1 (HIV-1)-based packaging cell lines are difficult to obtain, in part owing to...

High rate of genetic rearrangement during replication of a Moloney murine leukemia virus-based vector.

Varela-Echavarría, A, Prorock, C M, Ron, Y, Dougherty, J P

A protocol was designed to measure the forward mutation rate over an entire gene replicated as part of a Moloney murine leukemia virus-based vector. For these studies, the herpes simplex virus...

Reticuloendotheliosis type C and primate type D oncoretroviruses are members of the same receptor interference group.

Koo, H M, Gu, J, Varela-Echavarria, A, Ron, Y, Dougherty, J P

The reticuloendotheliosis viruses (REVs), originally isolated from avian species, constitute a group of retroviruses which are more closely related to mammalian retroviruses than to other avian...

Spleen necrosis virus, an avian retrovirus, can infect primate cells.

Koo, H M, Brown, A M, Ron, Y, Dougherty, J P

Spleen necrosis virus (SNV) is an avian retrovirus that can infect some mammalian cells such as dog cells as well as all avian cells tested to date. We were interested in testing whether SNV could...

Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors.

Bash, J, Zong, W X, Banga, S, Rivera, A, Ballard, D W, Ron, Y, ...

Jagged1 belongs to the DSL family of ligands for Notch receptors that control the proliferation and differentiation of various cell lineages. However, little is known about the transcription factors...

A murine model for B-lymphocyte somatic cell gene therapy.

Sutkowski, N, Kuo, M L, Varela-Echavarria, A, Dougherty, J P, Ron, Y

Mature primary B lymphocytes represent a potentially important cellular target for somatic cell gene therapy, which could prove advantageous for the treatment of certain metabolic and immunologic...

Genetic rearrangements occurring during a single cycle of murine leukemia virus vector replication: characterization and implications.

Parthasarathi, S, Varela-Echavarría, A, Ron, Y, Preston, B D, Dougherty, J P

Retroviruses evolve at rapid rates, which is presumably advantageous for responding to selective pressures. Understanding the basic mutational processes involved during retroviral replication is...

Inducible human immunodeficiency virus type 1 packaging cell lines.

Yu, H, Rabson, A B, Kaul, M, Ron, Y, Dougherty, J P

Packaging cell lines are important tools for transferring genes into eukaryotic cells. Human immunodeficiency virus type 1 (HIV-1)-based packaging cell lines are difficult to obtain, in part owing to...

High rate of genetic rearrangement during replication of a Moloney murine leukemia virus-based vector.

Varela-Echavarría, A, Prorock, C M, Ron, Y, Dougherty, J P

A protocol was designed to measure the forward mutation rate over an entire gene replicated as part of a Moloney murine leukemia virus-based vector. For these studies, the herpes simplex virus...

Reticuloendotheliosis type C and primate type D oncoretroviruses are members of the same receptor interference group.

Koo, H M, Gu, J, Varela-Echavarria, A, Ron, Y, Dougherty, J P

The reticuloendotheliosis viruses (REVs), originally isolated from avian species, constitute a group of retroviruses which are more closely related to mammalian retroviruses than to other avian...

Spleen necrosis virus, an avian retrovirus, can infect primate cells.

Koo, H M, Brown, A M, Ron, Y, Dougherty, J P

Spleen necrosis virus (SNV) is an avian retrovirus that can infect some mammalian cells such as dog cells as well as all avian cells tested to date. We were interested in testing whether SNV could...

Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors.

Bash, J, Zong, W X, Banga, S, Rivera, A, Ballard, D W, Ron, Y, ...

Jagged1 belongs to the DSL family of ligands for Notch receptors that control the proliferation and differentiation of various cell lineages. However, little is known about the transcription factors...

Antigen-induced proliferation assay for rabbit T lymphocytes. I. Characteristics of the response.

De Baetselier, P, Vaeck, M, De Smet, W, Ron, Y

An in vitro assay which measures specific antigen-induced proliferation of primed rabbit lymph node and peripheral blood cells is described. This response was found to be mediated by T cells, since...

Analgesic effect of topical sodium diclofenac 0.1% drops during retinal laser photocoagulation

Weinberger, D., Ron, Y., Lichter, H., Rosenblat, I., Axer-Siegel, R., Yassur, Y.

AIMS—To evaluate the analgesic effect of topical sodium diclofenac 0.1% during retinal laser photocoagulation.
METHODS—87 patients, 45 with proliferative diabetic retinopathy treated with two...