Uemura, Y. J., Aczel, A. A., Ajiro, Y., Carlo, J. P., Goko, T., Goldfeld, D. A., ...
We report muon spin relaxation ($\mu$SR) and magnetic susceptibility measurements on Cu(Cl,Br)La(Nb,Ta)$_{2}$O$_{7}$, which demonstrate: (a) the absence of static magnetism in (CuCl)LaNb$_{2}$O$_{7}$...
Observations of Oscillating Cavitation on a Flat Plate Hydrofoil (2001)
Sato, K., Tanada, M., Monden, S., Tsujimoto, Y.
An experimental investigation was made to clarify the characteristics of oscillating cavitation on a flat plate hydrofoil in a water tunnel. Dynamic the behavior of oscillating cavitation is...
Theoretical Study of Fluid Forces on a Centrifugal Impeller Rotating and Whirling in a Volute (1988)
Tsujimoto, Y., Acosta, A. J., Brennen, C. E.
Fluid forces on a rotating and whirling centrifugal impeller in a volute are analyzed with the assumption of a two-dimensional rotational, inviscid flow. For simplicity, the flow is assumed to be...
Emanuel, B.S., Cannizzaro, L.A., Magrath, I., Tsujimoto, Y., Nowell, P.C., Croce, C.M.
We have demonstrated that the chromosomal breakpoint at 22q11 of a Burkitt lymphoma cell line (PA682) with an 8;22 translocation interrupts the variable region of the lambda light chain locus. In...
Tsujimoto, Y., Acosta, A. J., Brennen, C. E.
Destabilizing fluid forces on a whirling centrifugal impeller rotating in a volute have been observed (Ref. 1). A quasisteady analysis neglecting shed vorticity (Ref. 2) or an unsteady analysis...
Molecular cloning of a human immunoglobulin {lambda} chain variable sequence (1984)
We have cloned a human Vλ cDNA sequence from an Igλ-producing human Burkitt lymphoma cell line (BL2) by taking advantage of a cloned constant region gene as a primer for cDNA synthesis instead of...
Dubois-Dauphin, M, Frankowski, H, Tsujimoto, Y, Huarte, J, Martinou, J C
In vitro, the overexpression of the bcl-2 protooncogene in cultured neurons has been shown to prevent apoptosis induced by neurotrophic factor deprivation. We have generated transgenic mice...
Differential effects of Bcl-2 on T and B cells in transgenic mice.
Katsumata, M, Siegel, R M, Louie, D C, Miyashita, T, Tsujimoto, Y, Nowell, P C, ...
We have produced bcl-2 transgenic mice by using a construct which mimics the t(14;18) translocation in human follicular lymphomas. Although lymphoid tissues from all transgenic mice contained high...
PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma.
Rosenberg, C L, Wong, E, Petty, E M, Bale, A E, Tsujimoto, Y, Harris, N L, ...
Rearrangement of the BCL1 (B-cell lymphoma 1) region on chromosome 11q13 appears to be highly characteristic of centrocytic lymphoma and also is found infrequently in other B-cell neoplasms....
A functional role for death proteases in s-Myc- and c-Myc-mediated apoptosis.
Kagaya, S, Kitanaka, C, Noguchi, K, Mochizuki, T, Sugiyama, A, Asai, A, ...
Upon activation, cell surface death receptors, Fas/APO-1/CD95 and tumor necrosis factor receptor-1 (TNFR-1), are attached to cytosolic adaptor proteins, which in turn recruit caspase-8...
Yamada, T, Yamaoka, S, Goto, T, Nakai, M, Tsujimoto, Y, Hatanaka, M
The Tax protein of human T-cell leukemia virus type I activates transcription of cellular and viral genes and can immortalize primary T lymphocytes. We have previously reported that the Tax protein...
Gauwerky, C E, Haluska, F G, Tsujimoto, Y, Nowell, P C, Croce, C M
We have analyzed the molecular genetics of the breakpoints involved in the t(8;14) and t(14;18) translocations of an acute pre-B-cell leukemia from a patient with a history of follicular lymphoma. In...
The biological activity of the human BCL-2 gene product was analyzed in an Epstein-Barr virus (EBV)-infected human lymphoblastoid B-cell line transfected with BCL-2 sequences driven by the simian...
Adachi, M, Cossman, J, Longo, D, Croce, C M, Tsujimoto, Y
The bcl-2 gene has been identified as a gene directly involved in the consistent chromosome translocation t(14;18), which is found in approximately 90% of human follicular lymphoma cases, and is a...
Yamada, M, Hudson, S, Tournay, O, Bittenbender, S, Shane, S S, Lange, B, ...
Approximately 80% of hematopoietic malignancies of the B-cell lineage carry only one or two immunoglobulin heavy chain gene rearrangements indicating their clonal origin. These rearrangements due to...
Haluska, F G, Tsujimoto, Y, Croce, C M
Recent molecular analyses of Burkitt lymphomas carrying the t(8;14) chromosome translocation have indicated that a dichotomy exists regarding the molecular mechanisms by which the translocations...
Tsujimoto, Y, Bashir, M M, Givol, I, Cossman, J, Jaffe, E, Croce, C M
In most human follicular lymphomas, the chromosome translocation t(14;18) occurs within two breakpoint clustering regions on chromosome 18, the major one at the 3' untranslated region of the bcl-2...
Promoter sequence of fibroin gene assigned by in vitro transcription system.
Tsujimoto, Y, Hirose, S, Tsuda, M, Suzuki, Y
We have shown that the silk fibroin gene from Bombyx mori is faithfully transcribed in an in vitro transcription system of the HeLa cell extract prepared by the method of Manley et al. [Manley, J....
Molecular cloning of a human immunoglobulin lambda chain variable sequence.
We have cloned a human V lambda cDNA sequence from an Ig lambda-producing human Burkitt lymphoma cell line (BL2) by taking advantage of a cloned constant region gene as a primer for cDNA synthesis...
Nagarajan, L, Louie, E, Tsujimoto, Y, Ar-Rushdi, A, Huebner, K, Croce, C M
The human homolog, hpim, of the murine pim-1 gene, which is activated in murine T-cell lymphomas by insertion of retrovirus proviral genomes in the pim-1 region, has been molecularly cloned; the...
We have determined that the bcl-2 (B-cell leukemia/lymphoma 2) gene is transcribed into three overlapping mRNAs, and we have cloned bcl-2 cDNA sequences. Sequence analysis of the bcl-2 cDNA clones...
Eguchi, Y, Ewert, D L, Tsujimoto, Y
The expression of human bcl-2 gene is de-regulated by t(14;18) translocation in most of follicular lymphoma. Recent studies indicated that the bcl-2 gene product has an ability to block apoptosis of...
Haluska, F G, Tsujimoto, Y, Croce, C M
One of the best analyzed tumor-specific cytogenetic abnormalities is the t(8;14) chromosomal translocation observed in cases of Burkitt's and undifferentiated lymphomas (ULs), and acute lymphoblastic...
Chromosomal orientation of the lambda light chain locus: V lambda is proximal to C lambda in 22q11.
Emanuel, B S, Cannizzaro, L A, Magrath, I, Tsujimoto, Y, Nowell, P C, Croce, C M
We have demonstrated that the chromosomal breakpoint at 22q11 of a Burkitt lymphoma cell line (PA682) with an 8;22 translocation interrupts the variable region of the lambda light chain locus. In...
Natural fibroin genes were purified from total DNA extracted from the fibroin-producer cells (posterior silk gland) and -nonproducer cells (middle silk gland or pupa) by two cycles of...
Erikson, J, Finan, J, Tsujimoto, Y, Nowell, P C, Croce, C M
We hybridized neoplastic cells from a patient with chromic lymphocytic leukemia of the B-cell type, which carried a reciprocal chromosomal translocation between chromosomes 11 (q13) and 14 (q32) with...
The human c-ros gene (ROS) is located at chromosome region 6q16----6q22.
Nagarajan, L, Louie, E, Tsujimoto, Y, Balduzzi, P C, Huebner, K, Croce, C M
The human homolog, c-ros, of the transforming gene, v-ros, of the avian sarcoma virus, UR2, has been isolated from a human genomic library. A single-copy fragment from the human c-ros genomic clone...
Involvement of Fas in regression of vaginal epithelia after ovariectomy and during an estrous cycle.
Suzuki, A, Enari, M, Eguchi, Y, Matsuzawa, A, Nagata, S, Tsujimoto, Y, ...
Fas, also called APO-1, belongs to the tumor necrosis factor/nerve growth factor receptor family and transmits an apoptotic signal within the cell by binding to the Fas ligand. Fas has been...
Inhibition of apoptosis by the actin-regulatory protein gelsolin.
Ohtsu, M, Sakai, N, Fujita, H, Kashiwagi, M, Gasa, S, Shimizu, S, ...
Gelsolin is an actin-regulatory protein that modulates actin assembly and disassembly, and is believed to regulate cell motility in vivo through modulation of the actin network. In addition to its...
Dubois-Dauphin, M, Frankowski, H, Tsujimoto, Y, Huarte, J, Martinou, J C
In vitro, the overexpression of the bcl-2 protooncogene in cultured neurons has been shown to prevent apoptosis induced by neurotrophic factor deprivation. We have generated transgenic mice...
Differential effects of Bcl-2 on T and B cells in transgenic mice.
Katsumata, M, Siegel, R M, Louie, D C, Miyashita, T, Tsujimoto, Y, Nowell, P C, ...
We have produced bcl-2 transgenic mice by using a construct which mimics the t(14;18) translocation in human follicular lymphomas. Although lymphoid tissues from all transgenic mice contained high...
PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma.
Rosenberg, C L, Wong, E, Petty, E M, Bale, A E, Tsujimoto, Y, Harris, N L, ...
Rearrangement of the BCL1 (B-cell lymphoma 1) region on chromosome 11q13 appears to be highly characteristic of centrocytic lymphoma and also is found infrequently in other B-cell neoplasms....
A functional role for death proteases in s-Myc- and c-Myc-mediated apoptosis.
Kagaya, S, Kitanaka, C, Noguchi, K, Mochizuki, T, Sugiyama, A, Asai, A, ...
Upon activation, cell surface death receptors, Fas/APO-1/CD95 and tumor necrosis factor receptor-1 (TNFR-1), are attached to cytosolic adaptor proteins, which in turn recruit caspase-8...
Yamada, T, Yamaoka, S, Goto, T, Nakai, M, Tsujimoto, Y, Hatanaka, M
The Tax protein of human T-cell leukemia virus type I activates transcription of cellular and viral genes and can immortalize primary T lymphocytes. We have previously reported that the Tax protein...
Gauwerky, C E, Haluska, F G, Tsujimoto, Y, Nowell, P C, Croce, C M
We have analyzed the molecular genetics of the breakpoints involved in the t(8;14) and t(14;18) translocations of an acute pre-B-cell leukemia from a patient with a history of follicular lymphoma. In...
The biological activity of the human BCL-2 gene product was analyzed in an Epstein-Barr virus (EBV)-infected human lymphoblastoid B-cell line transfected with BCL-2 sequences driven by the simian...
Adachi, M, Cossman, J, Longo, D, Croce, C M, Tsujimoto, Y
The bcl-2 gene has been identified as a gene directly involved in the consistent chromosome translocation t(14;18), which is found in approximately 90% of human follicular lymphoma cases, and is a...
Yamada, M, Hudson, S, Tournay, O, Bittenbender, S, Shane, S S, Lange, B, ...
Approximately 80% of hematopoietic malignancies of the B-cell lineage carry only one or two immunoglobulin heavy chain gene rearrangements indicating their clonal origin. These rearrangements due to...
Haluska, F G, Tsujimoto, Y, Croce, C M
Recent molecular analyses of Burkitt lymphomas carrying the t(8;14) chromosome translocation have indicated that a dichotomy exists regarding the molecular mechanisms by which the translocations...
Tsujimoto, Y, Bashir, M M, Givol, I, Cossman, J, Jaffe, E, Croce, C M
In most human follicular lymphomas, the chromosome translocation t(14;18) occurs within two breakpoint clustering regions on chromosome 18, the major one at the 3' untranslated region of the bcl-2...
Promoter sequence of fibroin gene assigned by in vitro transcription system.
Tsujimoto, Y, Hirose, S, Tsuda, M, Suzuki, Y
We have shown that the silk fibroin gene from Bombyx mori is faithfully transcribed in an in vitro transcription system of the HeLa cell extract prepared by the method of Manley et al. [Manley, J....
Molecular cloning of a human immunoglobulin lambda chain variable sequence.
We have cloned a human V lambda cDNA sequence from an Ig lambda-producing human Burkitt lymphoma cell line (BL2) by taking advantage of a cloned constant region gene as a primer for cDNA synthesis...
Nagarajan, L, Louie, E, Tsujimoto, Y, Ar-Rushdi, A, Huebner, K, Croce, C M
The human homolog, hpim, of the murine pim-1 gene, which is activated in murine T-cell lymphomas by insertion of retrovirus proviral genomes in the pim-1 region, has been molecularly cloned; the...
We have determined that the bcl-2 (B-cell leukemia/lymphoma 2) gene is transcribed into three overlapping mRNAs, and we have cloned bcl-2 cDNA sequences. Sequence analysis of the bcl-2 cDNA clones...
Eguchi, Y, Ewert, D L, Tsujimoto, Y
The expression of human bcl-2 gene is de-regulated by t(14;18) translocation in most of follicular lymphoma. Recent studies indicated that the bcl-2 gene product has an ability to block apoptosis of...
Haluska, F G, Tsujimoto, Y, Croce, C M
One of the best analyzed tumor-specific cytogenetic abnormalities is the t(8;14) chromosomal translocation observed in cases of Burkitt's and undifferentiated lymphomas (ULs), and acute lymphoblastic...
Chromosomal orientation of the lambda light chain locus: V lambda is proximal to C lambda in 22q11.
Emanuel, B S, Cannizzaro, L A, Magrath, I, Tsujimoto, Y, Nowell, P C, Croce, C M
We have demonstrated that the chromosomal breakpoint at 22q11 of a Burkitt lymphoma cell line (PA682) with an 8;22 translocation interrupts the variable region of the lambda light chain locus. In...
Natural fibroin genes were purified from total DNA extracted from the fibroin-producer cells (posterior silk gland) and -nonproducer cells (middle silk gland or pupa) by two cycles of...
Erikson, J, Finan, J, Tsujimoto, Y, Nowell, P C, Croce, C M
We hybridized neoplastic cells from a patient with chromic lymphocytic leukemia of the B-cell type, which carried a reciprocal chromosomal translocation between chromosomes 11 (q13) and 14 (q32) with...
The human c-ros gene (ROS) is located at chromosome region 6q16----6q22.
Nagarajan, L, Louie, E, Tsujimoto, Y, Balduzzi, P C, Huebner, K, Croce, C M
The human homolog, c-ros, of the transforming gene, v-ros, of the avian sarcoma virus, UR2, has been isolated from a human genomic library. A single-copy fragment from the human c-ros genomic clone...
Involvement of Fas in regression of vaginal epithelia after ovariectomy and during an estrous cycle.
Suzuki, A, Enari, M, Eguchi, Y, Matsuzawa, A, Nagata, S, Tsujimoto, Y, ...
Fas, also called APO-1, belongs to the tumor necrosis factor/nerve growth factor receptor family and transmits an apoptotic signal within the cell by binding to the Fas ligand. Fas has been...
Inhibition of apoptosis by the actin-regulatory protein gelsolin.
Ohtsu, M, Sakai, N, Fujita, H, Kashiwagi, M, Gasa, S, Shimizu, S, ...
Gelsolin is an actin-regulatory protein that modulates actin assembly and disassembly, and is believed to regulate cell motility in vivo through modulation of the actin network. In addition to its...