Runx2 induces acute myeloid leukemia in cooperation with Cbfbeta-SMMHC in mice (2009)
Kuo, Ya-Huei, Zaidi, Sayyed K., Gornostaeva, Svetlana, Komori, Toshihisa, Stein, Gary S., Castilla, Lucio H.
The core-binding factor (CBF) is a master regulator of developmental and differentiation programs, and CBF alterations are frequently associated with acute leukemia. The role of the CBF member RUNX2...
Kuo, Ya-Huei, Gerstein, Rachel M., Castilla, Lucio H.
The core-binding factor (CBF)-associated leukemia fusion protein CBFbeta-SMMHC impairs myeloid and lymphoid differentiation. By inhibiting RUNX function, the fusion oncoprotein predisposes...
Cbfbeta reduces Cbfbeta-SMMHC-associated acute myeloid leukemia in mice (2006)
Heilman, Susan Ann, Kuo, Ya-Huei, Goudswaard, Chantal S., Valk, Peter J., Castilla, Lucio H.
The gene encoding for core-binding factor beta (CBFbeta) is altered in acute myeloid leukemia samples with an inversion in chromosome 16, expressing the fusion protein CBFbeta-SMMHC. Previous studies...
Kuo, Ya-Huei, Landrette, Sean F., Heilman, Susan Ann, Perrat, Paola N., Garrett, Lisa, Liu, Pu P., ...
The acute myeloid leukemia (AML)-associated CBF beta-SMMHC fusion protein impairs hematopoietic differentiation and predisposes to leukemic transformation. The mechanism of leukemia progression,...
Kuo, Ya-Huei, Perrat, Paola N, ...
Recurrent chromosomal rearrangements are associated with the development of acute myeloid leukemia (AML). The frequent inversion of chromosome 16 creates the CBFB-MYH11 fusion gene that encodes the...
Landrette, Sean F., Kuo, Ya-Huei, Hensen, Karen, Perrat, Paola N., ...
Recurrent chromosomal rearrangements are associated with the development of acute myeloid leukemia (AML). The frequent inversion of chromosome 16 creates the CBFB-MYH11 fusion gene that encodes the...
A study on novel biological activities of pro-IGF-I E-peptides in human neuroblastoma cells (2001)
Insulin-like growth factors (IGFs) are mitogenic peptides that play important roles in development, growth and differentiation in vertebrates. Insulin-like growth factors (IGFs) are initially...
A study on novel biological activities of pro-IGF-I E-peptides in human neuroblastoma cells / (2001)
Abstract (2 leaves) bound with copy.
Kuo, Ya-Huei, Gerstein, Rachel M., Castilla, Lucio H.
The core-binding factor (CBF)–associated leukemia fusion protein CBFβ-SMMHC impairs myeloid and lymphoid differentiation. By inhibiting RUNX function, the fusion oncoprotein predisposes...