Yair Aharonowitz

Publication List Details

Period

1992 - 2008

Number

23

Co-Authors

and (2008)

Shaojie Zhang, Ilya Borovok, Yair Aharonowitz, Roded Sharan, Vineet Bafna

doi:10.1093/bioinformatics/btl232 A sequence-based filtering method for ncRNA identification

V.: A sequence-based filtering method for ncRNA identification and its application to searching for riboswitch elements (2006)

Shaojie Zhang, Ilya Borovok, Yair Aharonowitz, Roded Sharan, Vineet Bafna

Recent studies have uncovered an “RNA world”, in which non coding RNA (ncRNA) sequences play a central role in the regulation of gene expression. Computational studies on ncRNA have been directed...

A sequence-based filtering method for ncRNA identification and its application to searching for riboswitch elements (2006)

Zhang, Shaojie, Borovok, Ilya, Aharonowitz, Yair, Sharan, Roded, Bafna, Vineet

Motivation: Recent studies have uncovered an “RNA world”, in which non coding RNA (ncRNA) sequences play a central role in the regulation of gene expression. Computational studies on ncRNA have...

Analysis of Transcription of the Staphylococcus aureus Aerobic Class Ib and Anaerobic Class III Ribonucleotide Reductase Genes in Response to Oxygen

Masalha, Mahmud, Borovok, Ilya, Schreiber, Rachel, Aharonowitz, Yair, Cohen, Gerald

Staphylococcus aureus is a gram-positive facultative aerobe that can grow in the absence of oxygen by fermentation or by using an alternative electron acceptor. To investigate the mechanism by which...

Translocation in Bacillus subtilis: Irreversible Inactivation of Elongation Factor G and Viability of a Temperature-Sensitive Mutant

Aharonowitz, Yair, Ron, Eliora Z.

A temperature-sensitive mutant of Bacillus subtilis 168 lost its viability irreversibly when grown at temperatures higher than 50 C. It is suggested that this loss of viability is due to irreversible...

Transcriptional Regulation of the Staphylococcus aureus Thioredoxin and Thioredoxin Reductase Genes in Response to Oxygen and Disulfide Stress

Uziel, Orit, Borovok, Ilya, Schreiber, Rachel, Cohen, Gerald, Aharonowitz, Yair

In this report we describe the cloning, organization, and promoter analysis of the Staphylococcus aureus thioredoxin (trxA) and thioredoxin reductase (trxB) genes and their transcription in response...

Carbon Catabolite Regulation of Cephalosporin Production in Streptomyces clavuligerus

Aharonowitz, Yair, Demain, Arnold L.

Cephalosporin production by Streptomyces clavuligerus is regulated by some type of carbon catabolite control. Increasing concentrations of preferred carbon sources, such as glycerol and maltose,...

Role of a Cysteine Synthase in Staphylococcus aureus

Lithgow, James K., Hayhurst, Emma J., Cohen, Gerald, Aharonowitz, Yair, Foster, Simon J.

The gram-positive human pathogen Staphylococcus aureus is often isolated with media containing potassium tellurite, to which it has a higher level of resistance than Escherichia coli. The S. aureus...

A Multidomain Fusion Protein in Listeria monocytogenes Catalyzes the Two Primary Activities for Glutathione Biosynthesis

Gopal, Shubha, Borovok, Ilya, Ofer, Amos, Yanku, Michaela, Cohen, Gerald, Goebel, Werner, ...

Glutathione is the predominant low-molecular-weight peptide thiol present in living organisms and plays a key role in protecting cells against oxygen toxicity. Until now, glutathione synthesis was...

Coenzyme B12 Controls Transcription of the Streptomyces Class Ia Ribonucleotide Reductase nrdABS Operon via a Riboswitch Mechanism†

Borovok, Ilya, Gorovitz, Batia, Schreiber, Rachel, Aharonowitz, Yair, Cohen, Gerald

Ribonucleotide reductases (RNRs) catalyze the conversion of ribonucleotides to deoxyribonucleotides and are essential for de novo DNA synthesis and repair. Streptomycetes contain genes coding for two...

Analysis of Transcription of the Staphylococcus aureus Aerobic Class Ib and Anaerobic Class III Ribonucleotide Reductase Genes in Response to Oxygen

Masalha, Mahmud, Borovok, Ilya, Schreiber, Rachel, Aharonowitz, Yair, Cohen, Gerald

Staphylococcus aureus is a gram-positive facultative aerobe that can grow in the absence of oxygen by fermentation or by using an alternative electron acceptor. To investigate the mechanism by which...

Translocation in Bacillus subtilis: Irreversible Inactivation of Elongation Factor G and Viability of a Temperature-Sensitive Mutant

Aharonowitz, Yair, Ron, Eliora Z.

A temperature-sensitive mutant of Bacillus subtilis 168 lost its viability irreversibly when grown at temperatures higher than 50 C. It is suggested that this loss of viability is due to irreversible...

Transcriptional Regulation of the Staphylococcus aureus Thioredoxin and Thioredoxin Reductase Genes in Response to Oxygen and Disulfide Stress

Uziel, Orit, Borovok, Ilya, Schreiber, Rachel, Cohen, Gerald, Aharonowitz, Yair

In this report we describe the cloning, organization, and promoter analysis of the Staphylococcus aureus thioredoxin (trxA) and thioredoxin reductase (trxB) genes and their transcription in response...

Carbon Catabolite Regulation of Cephalosporin Production in Streptomyces clavuligerus

Aharonowitz, Yair, Demain, Arnold L.

Cephalosporin production by Streptomyces clavuligerus is regulated by some type of carbon catabolite control. Increasing concentrations of preferred carbon sources, such as glycerol and maltose,...

Role of a Cysteine Synthase in Staphylococcus aureus

Lithgow, James K., Hayhurst, Emma J., Cohen, Gerald, Aharonowitz, Yair, Foster, Simon J.

The gram-positive human pathogen Staphylococcus aureus is often isolated with media containing potassium tellurite, to which it has a higher level of resistance than Escherichia coli. The S. aureus...

A Multidomain Fusion Protein in Listeria monocytogenes Catalyzes the Two Primary Activities for Glutathione Biosynthesis

Gopal, Shubha, Borovok, Ilya, Ofer, Amos, Yanku, Michaela, Cohen, Gerald, Goebel, Werner, ...

Glutathione is the predominant low-molecular-weight peptide thiol present in living organisms and plays a key role in protecting cells against oxygen toxicity. Until now, glutathione synthesis was...

Coenzyme B12 Controls Transcription of the Streptomyces Class Ia Ribonucleotide Reductase nrdABS Operon via a Riboswitch Mechanism†

Borovok, Ilya, Gorovitz, Batia, Schreiber, Rachel, Aharonowitz, Yair, Cohen, Gerald

Ribonucleotide reductases (RNRs) catalyze the conversion of ribonucleotides to deoxyribonucleotides and are essential for de novo DNA synthesis and repair. Streptomycetes contain genes coding for two...

The Streptomyces NrdR Transcriptional Regulator Is a Zn Ribbon/ATP Cone Protein That Binds to the Promoter Regions of Class Ia and Class II Ribonucleotide Reductase Operons▿

Grinberg, Inna, Shteinberg, Tanya, Gorovitz, Batia, Aharonowitz, Yair, Cohen, Gerald, Borovok, Ilya

Ribonucleotide reductases (RNRs) catalyze the conversion of ribonucleotides to deoxyribonucleotides and are essential for de novo DNA synthesis and repair. Streptomyces spp. contain genes coding for...

NrdR Controls Differential Expression of the Escherichia coli Ribonucleotide Reductase Genes▿ †

Torrents, Eduard, Grinberg, Inna, Gorovitz-Harris, Batia, Lundström, Hanna, Borovok, Ilya, Aharonowitz, Yair, ...

Escherichia coli possesses class Ia, class Ib, and class III ribonucleotide reductases (RNR). Under standard laboratory conditions, the aerobic class Ia nrdAB RNR genes are well expressed, whereas...

Staphylococcus aureus ArcR Controls Expression of the Arginine Deiminase Operon▿ †

Makhlin, Julia, Kofman, Tzili, Borovok, Ilya, Kohler, Christian, Engelmann, Susanne, Cohen, Gerald, ...

We identified a single open reading frame that is strongly similar to ArcR, a member of the Crp/Fnr family of bacterial transcriptional regulators, in all sequenced Staphylococcus aureus genomes. The...

Functional Analysis of the Streptomyces coelicolor NrdR ATP-Cone Domain: Role in Nucleotide Binding, Oligomerization, and DNA Interactions▿ †

Grinberg, Inna, Shteinberg, Tatyana, Hassan, A. Quamrul, Aharonowitz, Yair, Borovok, Ilya, Cohen, Gerald

Ribonucleotide reductases (RNRs) are essential enzymes in all living cells, providing the only known de novo pathway for the biosynthesis of deoxyribonucleotides (dNTPs), the immediate precursors of...