Dou, Yali, Gorovsky, Martin A.
In Tetrahymena cells, constitutive phosphorylation of histone H1 phenocopies the loss of H1 from chromatin. Regulation of transcription by H1 phosphorylation is achieved by altering the overall...
Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors
Milne, Thomas A., Hughes, Christina M., Lloyd, Ricardo, Yang, Zhaohai, Rozenblatt-Rosen, Orit, Dou, Yali, ...
Mutations in the MEN1 gene are associated with the multiple endocrine neoplasia syndrome type 1 (MEN1), which is characterized by parathyroid hyperplasia and tumors of the pituitary and pancreatic...
Dou, Yali, Song, Xiaoyuan, Liu, Yifan, Gorovsky, Martin A.
In Tetrahymena thermophila, highly phosphorylated histone H1 of growing cells becomes partially dephosphorylated when cells are starved in preparation for conjugation. To determine the effects of H1...
MLL associates specifically with a subset of transcriptionally active target genes
Milne, Thomas A., Dou, Yali, Martin, Mary Ellen, Brock, Hugh W., Roeder, Robert G., Hess, Jay L.
MLL (mixed-lineage leukemia) is a histone H3 Lys-4 specific methyltransferase that is a positive regulator of Hox expression. MLL rearrangements and amplification are common in acute lymphoid and...
Dou, Yali, Gorovsky, Martin A.
In Tetrahymena cells, constitutive phosphorylation of histone H1 phenocopies the loss of H1 from chromatin. Regulation of transcription by H1 phosphorylation is achieved by altering the overall...
Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors
Milne, Thomas A., Hughes, Christina M., Lloyd, Ricardo, Yang, Zhaohai, Rozenblatt-Rosen, Orit, Dou, Yali, ...
Mutations in the MEN1 gene are associated with the multiple endocrine neoplasia syndrome type 1 (MEN1), which is characterized by parathyroid hyperplasia and tumors of the pituitary and pancreatic...
Dou, Yali, Song, Xiaoyuan, Liu, Yifan, Gorovsky, Martin A.
In Tetrahymena thermophila, highly phosphorylated histone H1 of growing cells becomes partially dephosphorylated when cells are starved in preparation for conjugation. To determine the effects of H1...
MLL associates specifically with a subset of transcriptionally active target genes
Milne, Thomas A., Dou, Yali, Martin, Mary Ellen, Brock, Hugh W., Roeder, Robert G., Hess, Jay L.
MLL (mixed-lineage leukemia) is a histone H3 Lys-4 specific methyltransferase that is a positive regulator of Hox expression. MLL rearrangements and amplification are common in acute lymphoid and...
Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases
Lee, Seunghee, Lee, Dong-Kee, Dou, Yali, Lee, Jeongkyung, Lee, Bora, Kwak, Eunyee, ...
Activating signal cointegrator-2 (ASC-2), a coactivator of multiple transcription factors that include retinoic acid receptor (RAR), associates with histone H3-K4 methyltranferases (H3K4MTs) MLL3 and...
Phosphorylation and an ATP-dependent process increase the dynamic exchange of H1 in chromatin
Dou, Yali, Bowen, Josephine, Liu, Yifan, Gorovsky, Martin A.
In Tetrahymena cells, phosphorylation of linker histone H1 regulates transcription of specific genes. Phosphorylation acts by creating a localized negative charge patch and phenocopies the loss of H1...
PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation
Hyllus, Dawin, Stein, Claudia, Schnabel, Kristin, Schiltz, Emile, Imhof, Axel, Dou, Yali, ...
The arginine methyltransferase PRMT6 (protein arginine methyltransferase 6) has been shown recently to regulate DNA repair and gene expression. As arginine methylation of histones is an important...