Yan Wang

Association of serum levels of lipid and its novel constituents with the different stages of esophageal carcinoma (2009)

Diao, Yutao, Li, Hao, Li, Huiqing, Zhou, Yingzhi, Ma, Qing, Wang, Yan, ...

Abstract Background The aim of the study was to evaluate the association of immunoglobulin G type of autoantibodies to oxidized low-density lipoprotein (oxLDL-lgG) and oxLDL-lgM with the progression...

Identification of tyrosine-phosphorylated proteins associated with metastasis and functional analysis of FER in human hepatocellular carcinoma cells (2009)

Li, Haiyu, Ren, Zhenggang, Kang, Xiaonan, Zhang, Lan, Li, Xuefei, Wang, Yan, ...

Abstract Background- Aberrant activity of tyrosine-phosphorylated proteins is commonly associated with HCC metastasis. Cell signaling events driven by these proteins are implicated in numerous...

Quantum Theory Approach for Neutron Single and Double-Slit Diffraction (2009)

Wu, Xiang-Yao, Hua, Zhong, Liu, Xiao-Jing, Wu, Yi-Heng, Tang, Hou-Li, Wang, Yan, ...

We provide a quantum approach description of neutron single and double-slit diffraction, with specific attention to the cold neutron diffraction ($\lambda \approx 20$\AA) carried out by Zeilinger et...

Nociception-induced spatial and temporal plasticity of synaptic connection and function in the hippocampal formation of rats: a multi-electrode array recording (2009)

Zhao, Xiao-Yan, Liu, Ming-Gang, Yuan, Dong-Liang, Wang, Yan, He, Ying, Wang, Dan-Dan, ...

Abstract Background Pain is known to be processed by a complex neural network (neuromatrix) in the brain. It is hypothesized that under pathological state, persistent or chronic pain can affect...

Schr\"odinger equation of general potential (2009)

Wu, Xiang-Yao, Liu, Xiao-Jing, Wu, Yi-Heng, Wang, Qing-Cai, Wang, Yan

It is well known that the Schr\"odinger equation is only suitable for the particle in common potential $V(\vec{r},t)$. In this paper, a general Quantum Mechanics is proposed, where the Lagrangian is...

Extending Special Relativity to Superluminal motion (2009)

Wu, Xiang-Yao, Liu, Xiao-Jing, Wu, Yi-Heng, Wang, Yan, Wang, Qing-Cai

Experiments done with single photon in the early 1990's produced a surprising result: that single photon pass through a photon tunnel barrier with a group velocity faster than the vacuum speed of...

Quantum wave equation of photon (2009)

Wu, Xiang-Yao, Liu, Xiao-Jing, Wu, Yi-Heng, Wang, Qing-Cai, Wang, Yan

In this paper, we give the quantum wave equations of single photon when it is in the free or medium space. With these equations, we can study light interference and diffraction with quantum approach....

Effect of ZnCdTe-Alloyed Nanocrystals on Polymer-Fullerene Bulk Heterojunction Solar Cells (2009)

Wang, Yan, Hou, Yanbing, Tang, Aiwei, Feng, Zhihui, Feng, Bin, Li, Yan, ...

The photovoltaic properties of solar cell based on the blends of poly[2-methoxy-5-(2-ethylhexoxy-1,4-phenylenevinylene) (MEH-PPV), fullerene (C60), and ZnCdTe-alloyed nanocrystals were investigated....

Design of packed-fiber solid-phase extraction device for analysis of the drug and its metabolite in plasma (2009)

Kang, Xue-Jun, Chen, Li-Qin, Wang, Yan, Zhang, Yi-Yun, Gu, Zhong-Ze

A mini-column packed with 1 mg electrospun polystyrene nanofibers (about 200∼400 nm in diameter) was designed for simple, fast extraction of drugs, diazepam and its major metabolite,...

Cytoplasmic Kaiso is associated with poor prognosis in non-small cell lung cancer (2009)

Dai, Shun-Dong, Wang, Yan, Miao, Yuan, Zhao, Yue, Zhang, Yong, Jiang, Gui-Yang, ...

Abstract Background Kaiso has been identified as a new member of the POZ-zinc finger family of transcription factors that are implicated in development and cancer. Although controversy still exists,...

Use of serial analysis of gene expression to reveal the specific regulation of gene expression profile in asthmatic rats treated by acupuncture (2009)

Yin, Lei-Miao, Jiang, Gong-Hao, Wang, Yu, Wang, Yan, Liu, Yan-Yan, Jin, Wei-Rong, ...

Abstract Background Asthma has become an important public health issue and approximately 300 million people have suffered from the disease worldwide. Nowadays, the use of acupuncture in asthma is...

Lack of association between polymorphisms of MASP2and susceptibility to SARS coronavirus infection (2009)

Wang, Yan, Yan, Jiangwei, Shi, Yuling, Li, Ping, Liu, Chuanxuan, Ma, Qingjun, ...

Abstract Background The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and...

Altered gene expression and miRNA expression associated with cancerous IEC-6 cell transformed by MNNG (2009)

Zhang, Bo, Wang, Xukai, Wang, Yan

Abstract Background Tumorigenesis is thought to be the consequence of gene mutation and disordered gene expression. However, the detailed molecular mechanism underlying the development and progress...

A hybrid material of graphene and poly (3,4-ethyldioxythiophene) with high conductivity, flexibility, and transparency (2009)

Xu, Yanfei, Wang, Yan, Liang, Jiajie, Huang, Yi, Ma, Yanfeng, Wan, Xiangjian, ...

A novel hybrid material prepared from graphene and poly (3,4-ethyldioxythiophene) (PEDOT) shows excellent transparency, electrical conductivity, and good flexibility, together with high thermal...

Detection of lymphangiogenesis in non-small cell lung cancer and its prognostic value (2009)

Sun, Jian-guo, Wang, Yan, Chen, Zheng-tang, Zhuo, Wen-lei, Zhu, Bo, Liao, Rong-xia, ...

Abstract Background Our aim was to detect lymphatic endothelial marker podoplanin, lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) and vascular endothelial growth factor receptor-3...

Decentralized Two-Sided Sequential Tests for A Normal Mean (2009)

Wang, Yan, Mei, Yajun

This article is concerned with decentralized sequential testing of a normal mean $\mu$ with two-sided alternatives. It is assumed that in a single-sensor network system with limited local memory,...

Common Solutions of an Iterative Scheme for Variational Inclusions, Equilibrium Problems, and Fixed Point Problems (2009)

Jian-Wen Peng, Yan Wang, David S. Shyu, Jen-Chih Yao

We introduce an iterative scheme by the viscosity approximate method for finding a common element of the set of solutions of a variational inclusion with set-valued maximal monotone mapping and...

Promotion of MAG-1 on Metastasis of Lung Cancer Cells in vitro and Its Expression in Lung Cancer Tissue of 24 Cases (2009)

Jinqiang ZHANG, Yuhong MENG, Huiyun LIN, Gang LIU, Yan WANG, Huihua CHEN, ...

Background and objective Tumor metastasis is a multistep process with many genes involved in. A novel gene MAG-1 , identified by suppression subtractive hybridization from lung cancer cells was found...

Time-Varying Myocardial Stress and Systolic Pressure-Stress Relationship. Role in Myocardial-Arterial Coupling in Hypertension (2009)

Chirinos, Julio, Segers, Patrick, Gupta, Amit, Swillens, Abigaïl, Rietzschel, Ernst, DE BUYZERE, MARC, ...

Background—Myocardial afterload depends on left ventricular (LV) cavity size, pressure, and wall thickness, all of which change markedly throughout ejection. We assessed the relationship between...

Existence and Asymptotic Behavior of Solutions for Weighted p(t)-Laplacian System Multipoint Boundary Value Problems in Half Line (2009)

Zhimei Qiu, Qihu Zhang, Yan Wang

This paper investigates the existence and asymptotic behavior of solutions for weighted p(t)-Laplacian system multipoint boundary value problems in half line. When the nonlinearity term...

VisANT 3.5: multi-scale network visualization, analysis and inference based on the gene ontology (2009)

Hu, Zhenjun, Hung, Jui-Hung, Wang, Yan, Chang, Yi-Chien, Huang, Chia-Ling, Huyck, Matt, ...

Despite its wide usage in biological databases and applications, the role of the gene ontology (GO) in network analysis is usually limited to functional annotation of genes or gene sets with...

Existence and Asymptotic Behavior of Solutions for Weighted p(t)-Laplacian System Multipoint Boundary Value Problems in Half Line (2009)

Zhimei Qiu, Qihu Zhang, Yan Wang

This paper investigates the existence and asymptotic behavior of solutions for weighted p(t)-Laplacian system multipoint boundary value problems in half line. When the nonlinearity term f(t,⋅,⋅)...

PARP-1 suppresses adiponectin expression through poly(ADP-ribosyl)ation of PPAR{gamma} in cardiac fibroblasts (2009)

Huang, Dan, Yang, Chongzhe, Wang, Yan, Liao, Yuhua, Huang, Kai

Aims Our aim was to explore the mechanism underlying the transcriptional regulation of adiponectin and its receptors (AdipoR) in cultured rat cardiac fibroblasts. Methods and results Using western...

The alternative oxidase of Candida albicans causes reduced fluconazole susceptibility (2009)

Yan, Lan, Li, Miaohai, Cao, Yongbing, Gao, Pinghui, Cao, Yingying, Wang, Yan, ...

Objectives To evaluate the effect of Candida albicans mitochondrial respiratory status on antifungal azole susceptibility. Methods The inhibitors cyanide and salicylhydroxamic acid (SHAM) were each...

Effects of intratumoral injection of microspheres containing cobra venom cytotoxin on transplanted human hepatoma in nude mice (2009)

Yan WANG, Li-wu LIN

Objective: To evaluate the safety and efficacy of intratumoral injection of polylactic-co-glycolic acid (PLGA) microspheres containing cobra venom cytotoxin in nude mice with transplanted human...

Differences in conformational dynamics of [Pt3(HPTAB)]6+-DNA adducts with various cross-linking modes (2009)

Zhu, Yanyan, Wang, Yan, Chen, Guangju

We present here molecular dynamics simulations and DNA conformational dynamics for a series of trinuclear platinum [Pt3(HPTAB)]6+-DNA adducts [HPTAB = N,N,N′,N′,N′′,N′′-hexakis...

(1S*,4aR*,5S*,6S*,8aR*)-3-Benzyl-1-methyl-5,6-diphenyl-3,4,4a,5,6,8a-hexahydro-1H-2,3-benzoxazin-4-one (2009)

Yan Wang, Jin-Long Wu

In the title compound, C28H27NO2, the oxazinone ring adopts a twist-boat conformation and the cyclohexene ring has a twisted envelope conformation. The crystal structure is stabilized by weak...

Expression and Significance of Nrf2 and Its Target Genes in Pulmonary Adenocarcinoma A549 Cells Resistant to Cisplatin (2009)

Kairu ZHANG, Huiqin YAN, Yan WANG, Li MA, Qinghua ZHOU

Background and objective Nuclear factor erythroid-2 related factor 2 (Nrf2) is a key transcription factor in oxidation-reduction reaction. It has been proved that Nrf2 is relevant to...

Silica Sulfuric Acid Promotes Aza-Michael Addition Reactions under Solvent-Free Condition as a Heterogeneous and Reusable Catalyst (2009)

Yan Wang, Yan-Qin Yuan, Sheng-Rong Guo

A highly efficient, inexpensive, recyclable, convenient, and green protocol for chemoselective aza-Michael addition reactions of amines/thiols to α,β-unsaturated compounds using silica sulfuric...

Departmento de Sistemas Informàticos y Computación, (2008)

Kieron Messer, Josef Kittler, Mohammad Sadeghi, Miroslav Hamouz, Alexey Kostyn, Sebastien Marcel, ...

This paper details the results of a Face Authentication Test (FAT2004) [2] held in conjunction with the 17th International Conference on Pattern Recognition. The contest was held on the publicly...

Pep-3D-Search: a method for B-cell epitope prediction based on mimotope analysis (2008)

Huang, Yan, Bao, Yong, Guo, Shu, Wang, Yan, Zhou, Chun, Li, Yu

Abstract Background The prediction of conformational B-cell epitopes is one of the most important goals in immunoinformatics. The solution to this problem, even if approximate, would help in...

Strong field effects on pulsar arrival times: circular orbits and equatorial beams (2008)

Wang, Yan, Jenet, Frederick A., Creighton, Teviet, Price, Richard H.

If a pulsar orbits a supermassive black hole, the timing of pulses that pass close to the hole will show a variety of strong field effects. To compute the intensity and timing of pulses that have...

SINGLE-TRIAL CLASSIFICATION OF ERPS USING SECOND-ORDER BLIND IDENTIFICATION (SOBI) (2008)

Yan Wang, Matthew T. Sutherland, Lori L. Sanfratello, Akaysha C. Tang

Single-trial classification of EEG signals has received increasing attention in both basic research and for the development of EEG based Brain Computer Interfaces (BCI). Typically, such...

A Mobile Autonomous Agent-based Secure Payment Protocol Supporting Multiple Payments (2008)

Yan Wang

In agent based e-commerce applications, it is challengeable to employ one mobile agent to complete all transactions including payments due to the security consideration. In this paper, we propose a...

Identification of a differentially expressed gene, ACL, between Meishan × Large White and Large White × Meishan F1 hybrids and their parents (2008)

Ren, Zhu-Qing, Wang, Yan, Xu, Yong-Jie, Wang, Lin-Jie, Lei, Ming-Gang, Zuo, Bo, ...

Abstract ATP-citrate lyase (ACL), one of the lipogenic enzymes, catalyses the formation of acetyl-coenzyme A (CoA) involved in the synthesis of fatty acid and cholesterol. In pig, very little is...

Genetic characterization of Measles Viruses in China, 2004 (2008)

Zhang, Yan, Ji, Yixin, Jiang, Xiaohong, Xu, Songtao, Zhu, Zhen, Zheng, Lei, ...

Abstract Genetic characterization of wild-type measles virus was studied using nucleotide sequencing of the C-terminal region of the N protein gene and phylogenetic analysis on 59 isolates from 16...

Molecular cloning, characterization and expression of phenylalanine ammonia-lyase gene from Ginkgo biloba   (2008)

Xu, Feng, Cai, Rong, Cheng, Shuiyuan, Du, Hewei, Wang, Yan, Cheng, Shuhan

A full-length cDNA and genomic DNA of phenylalanine ammonia-lyase gene, which catalyzes the first step in the flavonoid biosynthetic pathway, were isolated from Ginkgo biloba   for the first time...

A class of Solvable Lie algebras (2008)

Wang, Yan, Cui, Ran, Deng, ShaoQiang

All finite-dimensional indecomposable solvable Lie algebras g, having the filiform Lie algebra Q_(2m+1) as the nilradical, are studied and classified. It turns out that the dimension of g is at most...

The Mock LISA data challenges: from challenge 1B to challenge 3 (2008)

Babak, Stanislav, Baker, John, Benacquista, Matthew, Cornish, Neil, Crowder, Jeff, Larson, Shane, ...

Also archived in arXiv:0806.2110 v1 Jun 12, 2008. Proceedings from the 12th Gravitational Wave Data Analysis Workshop, Cambridge MA, from 13-16 December 2007

The Mock LISA data challenges: from challenge 1B to challenge 3 (2008)

Babak, Stanislav, Baker, John G., Benacquista, Matthew J., Cornish, Neil J., Crowder, Jeff, Larson, Shane L., ...

The Mock LISA Data Challenges are a programme to demonstrate and encourage the development of LISA data-analysis capabilities, tools and techniques. At the time of this workshop, three rounds of...

Beijing 100084, P.R. China. (2008)

Kieron Messer, Josef Kittler, Mohammad Sadeghi, Miroslav Hamouz, Alexey Kostin, Fabien Cardinaux, ...

Carnegie Mellon University. This paper details the results of a Face Authentication Test (FAT2004) [5] held in conjunction with the 17th International Conference on Pattern Recognition. The contest...

The Journal of Cell Biology JCB Article (2008)

Yuri G. Strukov, Yan Wang, Andrew S. Belmont

Engineered chromosome regions with altered sequence composition demonstrate hierarchical large-scale folding within metaphase chromosomes

A spatially shifted beam approach to subwavelength focusing (2008)

Markley, Loic, Wong, Alex M. H., Wang, Yan, Eleftheriades, George V.

Although negative-refractive-index metamaterials have successfully achieved subwavelength focusing, image resolution is limited by the presence of losses. In this Letter, a metal transmission screen...

The Mock LISA Data Challenges: from Challenge 1B to Challenge 3 (2008)

Babak, Stanislav, Baker, John G., Benacquista, Matthew J., Cornish, Neil J., Crowder, Jeff, Larson, Shane L., ...

The Mock LISA Data Challenges are a programme to demonstrate and encourage the development of LISA data-analysis capabilities, tools and techniques. At the time of this workshop, three rounds of...

Adaptable Transaction Processing in the Web Services Domain (2008)

Yan Wang, Weihai Yu

The advent of Web Services technologies both demands interoperability and adaptability of various transaction processing models, and provides a solid basis for this goal. In this paper we first give...

To whom requests for proofs are to be addressed: (2008)

Makoto Kano, Shuichi Tsutsumi, Nobutaka Kawahara, Yan Wang, Akitake Mukasa, Takaaki Kirino, ...

A meta-clustering analysis indicates distinct pattern alteration between two series of Gene Expression profiles for induced ischemic tolerance in rats

A Security and Trust Framework for (2008)

Yan Wang, Vijay Varadharajan, Yan Wang, Vijay Varadharajan

P2P based e-commerce (EC) is becoming increasingly significant where security and trust are two of the most critical issues. This paper discusses and proposes a secure infrastructure with peer...

Semantic Tolerancing (2008)

G. Bayraksan, W. Lin, Y. Son, R. Wysk, Yan Wang

Recently we developed a new tolerance modeling scheme, semantic tolerance modeling, to enable interpretable and accurate tolerance analysis. In this paper, a new dimensioning and tolerancing...

A Novel Computational Based Method for Discovery of Sequence Motifs from Coexpressed Genes (2008)

Wengang Zhou, Hong Zhu, Guixia Liu, Yanxin Huang, Yan Wang, Dongbing Han, ...

The transcriptional regulation of gene expression is a key mechanism in the functioning of the cell. It is mostly affected through acting element binding to specific sequence motifs. In this paper,...

Periodic Loci Surface Reconstruction in Nano Material Design (2008)

G. Bayraksan, W. Lin, Y. Son, R. Wysk, Yan Wang

Recently we proposed a periodic surface (PS) model for computer aided nano design (CAND). This implicit surface model allows for parametric model construction at atomic, molecular, and meso scales....

Semantic Tolerancing with Generalized Intervals (2008)

Yan Wang

A new tolerance modeling scheme, semantic tolerance modeling, was recently developed to enable interpretable tolerance analysis. In this paper, a new dimensioning and tolerancing practice, semantic...

Modeling Total Cost of Ownership Utilizing Interval-Based Reliable Simulation Technique in Reverse Logistics Management (2008)

Heba Hamza, Yan Wang, Bopaya Bidanda

Reverse logistics involving closed-loop supply chains in various industry sectors has received growing attention throughout this decade. Reverse logistics considers several channels of reverse...

COST-EFFECTIVE PRODUCT RELIZATION: SERVICE-ORIENTED ARCHITECTURE FOR INTEGRATED PRODUCT LIFE-CYCLE MANAGEMENT (2008)

Bart O. Nnaji, Yan Wang, Kyoung-yun Kim

Abstract: The worldwide availability of technology, capital, information, and labor makes today’s manufacturing enterprises global. Information incompleteness, inconsistency, and improccessability...

Evolving Hierarchical RBF Neural Networks for Breast Cancer Detection (2008)

Yuehui Chen, Yan Wang, Bo Yang

Abstract. Hierarchical RBF networks consist of multiple RBF networks assembled in different level or cascade architecture. In this paper, an evolved hierarchical RBF network was employed to detect...

4D Geometry Compression based on Lifting Wavelet Transform (2008)

Yan Wang, Heba Hamza

3D geometry is one of the most extensively used data in military, engineering, and multimedia communication. In a distributed environment, efficient visual data exchange is desirable for real-time...

Intellectual Property Protection in Collaborative Design through Lean Information Modeling and Sharing (2008)

Yan Wang, Pamela N. Ajoku, José C. Brustoloni, Bartholomew O. Nnaji, William Kepler, Whiteford Professor, ...

Establishing efficient, effective, and trustworthy engineering collaboration while protecting intellectual property is vital to maintain organizational competence in today’s global business...

Multicolor up-conversion emissions of Tm3+/Er3+/Yb3+ tri-doped YF3 phosphors (2008)

Cao, Chunyan, Qin, Weiping, Zhang, Jisen, Zhang, Jishuang, Wang, Yan, Jin, Ye, ...

Tm3+/Er3+/Yb3+ tri-doped yttrium fluoride (YF3) phosphors were prepared by a facile hydrothermal method. X-ray topographic analysis found that the phosphors were crystallized products. Their sizes...

Synthesis and photophysical properties of core-shell Eu(DBM)(3)phen/TiO2 nanohybrids (2008)

Qin, Weiping, Zhao, Dan, Zhang, Jisen, Zhang, Jishuang, Wang, Yan, Cao, Chunyan, ...

The core-shell titania (TiO2) hybrid spheres embedded with tris(dibenzoylmethanato)phenanthroline [Eu-(DBM)(3)phen] complex clusters were fabricated by a modified Stober method. Under ultraviolet...

Declaration (2008)

Yan Wang, C Yan Wang

I hereby declare that I am the sole author of this thesis. This is a true copy of the thesis, including any required final revisions, as accepted by my examiners. I understand that my thesis may be...

A novel method to quantify local CpG methylation density by regional methylation elongation assay on microarray (2008)

Zhang, Dingdong, Wang, Yan, Bai, Yunfei, Ge, Qinyu, Qiao, Yingjuan, Luo, Junfeng, ...

Abstract Background DNA methylation based techniques are important tools in both clinical diagnostics and therapeutics. But most of these methods only analyze a few CpG sites in a target region....

Clinic outcome of gefitinib in sixty-nine elderly patients with lung adenocarcinoma (2008)

Yan WANG, Xiangru ZHANG, Bin WANG, Ziping WANG, Datong CHU, Yan SUN

Background and Objective To evaluate the efficacy and safety of gefitinib, an orally active epidermal growth factor receptor tyrosine kinase inhibitor(EGFR-TKI), in elderly patients with other types...

Expression and significance of p120ctn isoforms in lung squamous cell carcinomas (2008)

Yuan MIAO, Yang LIU, Yan WANG, Enhua WANG

Background and Objective It has been proven that p120ctn plaied an important role in cell adhesion and correlates with tumorigenesis significantly, the aim of this work is to investigate the...

High Expression of TCF-4 Positively Correlated with Lung Cancer Progression (2008)

Lianhe YANG, Hongtao XU, Yan WANG, Yang LIU, Yue ZHAO, Shundong DAI, ...

Background and objective TCF-4 is an important downstream molecule of Wnt signaling pathway, but studies on the expression level and significance of TCF-4 in lung cancer were still limited. The aim...

The proliferation promoting effects of MAG-2 on human lung cancer cell PLA801 (2008)

Jinqiang ZHANG, Yuhong MENG, Gang LIU, Huihua CHEN, Yan WANG, Yuanji XU, ...

Background and objective Both tumor proliferation and metastasis are multistep processes with many genes involved. A novel gene MAG-2, which may have close correlation with lung cancer metastasis,...

The Mock LISA Data Challenges: from Challenge 1B to Challenge 3 (2008)

Babak, Stanislav, Baker, John G., Benacquista, Matthew J., Cornish, Neil J., Crowder, Jeff, Larson, Shane L., ...

The Mock LISA Data Challenges are a programme to demonstrate and encourage the development of LISA data-analysis capabilities, tools and techniques. At the time of this workshop, three rounds of...

Subacute Oral Exposure to Dibromoacetic Acid Induced Immunotoxicity and Apoptosis in the Spleen and Thymus of the mice (2008)

Gao, Shuying, Wang, Yan, Zhang, Ping, Dong, Yucui, Li, Baixiang

Dibromoacetic acid (DBA) is a haloacetic acid that is present in drinking water as a by-product of chlorinated disinfection. To evaluate its potential adverse health effects, the immunotoxicological...

Multiple Random Beams Selection Exploiting Chordal Distances (2008)

TANG, Lan, ZHU, Pengcheng, YOU, Xiaohu, WANG, Yan

We consider a time-division multiple access (TDMA) transmission scheme in MIMO broadcast channels. To cope with the fairness issue in heterogeneous networks with slow fading, an opportunistic...

A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women (2008)

Wang, Yan, Hu, Zhibin, Liang, Jie, Wang, Zhanwei, Tang, Jinhai, Wang, Shui, ...

Telomerase reactivation, which prevents telomere shortening and maintains cell viability, is crucial for the continued growth or progression of cancer cells. A minisatellite tandem repeat, MNS16A,...

Common Solutions of an Iterative Scheme for Variational Inclusions, Equilibrium Problems, and Fixed Point Problems (2008)

Jian-Wen Peng, Yan Wang, David S. Shyu, Jen-Chih Yao

We introduce an iterative scheme by the viscosity approximate method for finding a common element of the set of solutions of a variational inclusion with set-valued maximal monotone mapping and...

Genetic variants in fibroblast growth factor receptor 2 (FGFR2) contribute to susceptibility of breast cancer in Chinese women (2008)

Liang, Jie, Chen, Peizhan, Hu, Zhibin, Zhou, Xiaoyi, Chen, Lu, Li, Mian, ...

Fibroblast growth factor receptor 2 (FGFR2) belongs to the FGFR family, which plays an important role in cell growth, invasiveness, motility and angiogenesis. In human breast cancer, expression of...

Novel needle immersed vitrification: a practical and convenient method with potential advantages in mouse and human ovarian tissue cryopreservation (2008)

Wang, Yan, Xiao, Zhun, Li, Lei, Fan, Wei, Li, Shang-Wei

BACKGROUND Ovarian tissue cryopreservation may be a potential method of preserving fertility in women who have experienced gonadotoxic treatments. To improve the efficiency of existing...

BioMed Central (2008)

Bmc Bioinformatics, Yan Xin Huang, Yong Li Bao, Shu Yan Guo, Yan Wang, Chun Guang Zhou, ...

Software Pep-3D-Search: a method for B-cell epitope prediction based on mimotope analysis

Histopathology of Corneal Wound Healing after . . . (2007)

Yan Wang

ere used during the laser procedure. A 193 nm argon-fluoride excimer laser (Nidek EC-5000, Nidek, Japan) was used. This system incorporates an innovative scanning method for excimer laser delivery....

Bayesian Sample Size Computations in Complex Models with Application to Repeated Measures Random Effects Model Design (2007)

Robert Weiss, Yan Wang

Bayesian methodology is developed to chose the sample size in complex problems where testing a null hypothesis is of interest. The approach permits propagation of uncertainty in quantities which are...

Dispatching Mobile Agents with Secure Routes in Parallel (2007)

Yan Wang, Kian-lee Tan

Abstract. In a distributed environment like the Internet, mobile agents can be employed to perform autonomous tasks such as searching and negotiating. However, for mobile agents to be widely...

1 Measuring Education Inequality: Gini Coefficients of Education (2007)

Vinod Thomas, Vinod Thomas, Yan Wang, Yan Wang, Xibo Fan, Xibo Fan

comments and suggestions, and the Bank’s Research Committee for providing a part of the funding. The findings, interpretations and conclusions expressed here are those of the authors. They do not...

* Senior economist and consultant, The World Bank Institute. The authors thank Vinod Thomas (2007)

Yan Wang, Yudong Yao, Pierre-richard Agénor, Mansoor Dailami, Bill Easterly, ...

Output collapses and crises are a fact of life. In this paper we propose a new measurement for economic downside risk and severity: Growth at Risk. It is similar to the concept of Value at Risk in...

Shaohua Chen and Yan Wang* The World Bank (2007)

Shaohua Chen, Yan Wang

This paper investigates the recent trends in poverty and inequality since the 1990s, and decomposes poverty reduction to see who has benefited most from China’s economic growth. We find that first,...

1,2 (2007)

Yan Wang, Xin Gui Fang, D. Frank Hsu

A G-Frobenius graph, as defined recently by Fang, Li, and Praeger, is a connected orbital graph of a Frobenius group G = K:H with Frobenius kernel K and Frobenius complement H. # is also shown to be...

Web Mining and Knowledge Discovery of Usage Patterns CS 748T Project (Part I) (2007)

Yan Wang

Web mining is a very hot research topic which combines two of the activated research areas:

Unilateral pedicle screws asymmetric tethering: an innovative method to create idiopathic deformity (2007)

Zhang, Yonggang, Wang, Yan, Zheng, Guoquan, Zhang, Xuesong, Zhang, Ruyi, Zhang, Wei

Abstract Objective To evaluate the feasibility of the method that unilateral pedicle screws asymmetric tethering in concave side in combination with convex rib resection for creating idiopathic...

Proteome analysis of human gastric cardia adenocarcinoma by laser capture microdissection (2007)

Cheng, Yan, Zhang, Jun, Li, Yang, Wang, Yan, Gong, Jun

Abstract Background The incidence of gastric cardiac adenocarcinoma (GCA) has been increasing in the past two decades in China, but the molecular changes relating to carcinogenesis have not been well...

Downregulation of Rap1GAP contributes to Ras transformation. (2007)

Tsygankova, Oxana, Prendergast, Gregory V, Puttaswamy, Kanchan, Wang, Yan, Feldman, Michael D, Wang, Hongbin, ...

Although abundant in well-differentiated rat thyroid cells, Rap1GAP expression was extinguished in a subset of human thyroid tumor-derived cell lines. Intriguingly, Rap1GAP was downregulated...

Drug-Induced Epigenetic Changes Produce Drug Tolerance (2007)

Yan Wang, Harish R. Krishnan, Alfredo Ghezzi, Nigel S. Atkinson

Tolerance to drugs that affect neural activity is mediated, in part, by adaptive mechanisms that attempt to restore normal neural excitability. Changes in the expression of ion channel genes are...

Impact of Feedback Error on Transmit Beamforming with Finite Rate Feedback (2007)

ZHU, Pengcheng, TANG, Lan, WANG, Yan, YOU, Xiaohu

In this letter, we study the impact of feedback error on transmit beamforming systems with finite rate feedback. The feedback channel is modeled as a uniform symmetric channel. The outage...

Electronic and Vibrational Properties of gamma-AlH3 (2007)

Wang, Yan, Yan, Jia-An, Chou, M. Y.

Aluminum hydride (alane) AlH_3 is an important material in hydrogen storage applications. It is known that AlH_3 exists in multiply forms of polymorphs, where $\alpha$-AlH_3 is found to be the most...

Secure quantum key distribution network with Bell states and local unitary operations (2007)

Li, Chun-Yan, Zhou, Hong-Yu, Wang, Yan, Deng, Fu-Guo

We propose a theoretical scheme for secure quantum key distribution network following the ideas in quantum dense coding. In this scheme, the server of the network provides the service for preparing...

Urban health insurance reform and coverage in China using data from National Health Services Surveys in 1998 and 2003 (2007)

Xu, Ling, Wang, Yan, Collins, Charles D, Tang, Shenglan

Abstract Background In 1997 there was a major reform of the government run urban health insurance system in China. The principal aims of the reform were to widen coverage of health insurance for the...

Prostaglandin E2receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated α-synuclein (2007)

Jin, Jinghua, Shie, Feng-Shiun, Liu, Jun, Wang, Yan, Davis, Jeanne, Schantz, Aimee M, ...

Abstract Background The pathogenesis of idiopathic Parkinson's disease (PD) remains elusive, although evidence has suggested that neuroinflammation characterized by activation of resident microglia...

Exploring multiple-perspective learning and its impact on problem diagnosis and perspective preference (2007)

Wang, Yan

Researchers have argued that using multiple perspectives in learning can increase learners' cognitive flexibility, critical thinking and problem solving abilities. There is no common understanding,...

Docetaxel weekly regimen in conjunction with RF hyperthermia for pretreated locally advanced non-small cell lung cancer: a preliminary study (2007)

Jiang Zhu, Yan Wang, Ming Jiang, Yu Yang

Abstract Background To evaluate the feasibility and therapeutic effect of chemotherapy combined with regional radio frequency hyperthermia for pretreated locally advanced non-small cell lung cancer....

The Design of a rule-based and event-driven trust management framework (2007)

Wang, Yan, Lin, Kwei-Jay, Wong, Duncan S, Varadharajan, Vijay

In both e-commerce (EC) and service-oriented computing (SOC) environments, sellers or service providers interact with customers or service clients for services or transactions. From the point view of...

Role-based recommendation and trust evaluation (2007)

Wang, Yan, Varadharajan, Vijay

In general, in most trust evaluation systems, the evaluation of a target party under investigation relies on the trust ratings from responding peers/parties who have direct interactions with the...

Mobile agent and web service integration security architecture (2007)

Zhang, Junqi, Wang, Yan, Varadharajan, Vijay

Mobile agent technology and Web service technology compensate each other and play very important roles in e-service applications. The mechanism of Web services technology naturally provides a...

A New security scheme for integration of mobile agents and web services (2007)

Zhang, Junqi, Wang, Yan, Varadharajan, Vijay

Web services specification provides an open standard for the distributed service oriented architecture. It is widely used in Internet and pervasive networks supporting wireless mobile devices. A...

A Dynamic Voltage Scaling Algorithm for Dynamic Workloads* (2007)

Albert Mo, Kim Cheng, Yan Wang, Albert Mo, Kim Cheng, Yan Wang

Dynamic Voltage Scaling (DVS) is a promising method to achieve energy saving by slowing down the processor into multiple frequency levels in battery-operated embedded systems. However, the worst case...

Exploring multiple-perspective learning and its impact on problem diagnosis and perspective preference. (2007)

Wang, Yan

Source: Dissertation Abstracts International, Volume: 68-11, Section: A, page: 4678.

Phase II trial of sequential gefitinib after minor response or partial response to chemotherapy in Chinese patients with advanced non-small-cell lung cancer (2006)

Xu, Jian, Han, Yu, Li, Yue, Zhao, Chuan, Wang, Yan, Paradiso, Angelo

Abstract Background Basic research of gefitinib (Iressa, ZD1839) has demonstrated the combination effects of gefitinib and chemotherapy were sequence-dependent. To evaluate the efficacy of sequential...

Clinical report of cervical arthroplasty in management of spondylotic myelopathy in Chinese (2006)

Wang, Yan, Zhang, Xuesong, Xiao, Songhua, Lu, Ning, Wang, Zheng, Zhou, Mi

Abstract Objectives To investigate clinical effects and manual operational point of Bryan cervical disc prosthesis in Chinese, to observe the stability and range of movement (ROM) post-operatively....

Isolation and characterization of a carotenoid oxygenase gene from Chlorella zofingiensis (Chlorophyta) (2006)

Wang, Yan, Sandmann, Gerhard

The green alga Chlorella zofingiensis produces large amounts of the valuable ketocarotenoid astaxanthin under dark, heterotrophic growth conditions, making it potentially employable for commercial...

Induction of the HIV-1 Tat co-factor cyclin T1 during monocyte differentiation is required for the regulated expression of a large portion of cellular mRNAs (2006)

Yu, Wendong, Wang, Yan, Shaw, Chad A, Qin, Xiao-Feng, Rice, Andrew P

Abstract Background P-TEFb, a general RNA polymerase II elongation factor, is composed of CDK9 (cyclin-dependent kinase 9) as a catalytic unit and either cyclin T1, T2 or K as a regulatory subunit....

Characterization of Caking and Cake Strength in a Potash Bed (2006)

Wang, Yan

When a water soluble granular fertilizer, such as potash, is wetted and then dried during storage and transportation processes, clumps or cakes often form in the material even when the maximum...

Characterization of Caking and Cake Strength in a Potash Bed (2006)

Wang, Yan

When a water soluble granular fertilizer, such as potash, is wetted and then dried during storage and transportation processes, clumps or cakes often form in the material even when the maximum...

Characterization of Caking and Cake Strength in a Potash Bed (2006)

Wang, Yan

When a water soluble granular fertilizer, such as potash, is wetted and then dried during storage and transportation processes, clumps or cakes often form in the material even when the maximum...

Laser Desorption Solid Phase Microextraction (2006)

Wang, Yan

The use of laser desorption as a sample introduction method for solid phase microextraction (SPME) has been investigated in this research project. Three different types of analytical instruments,...

Laser Desorption Solid Phase Microextraction (2006)

Wang, Yan

The use of laser desorption as a sample introduction method for solid phase microextraction (SPME) has been investigated in this research project. Three different types of analytical instruments,...

Laser Desorption Solid Phase Microextraction (2006)

Wang, Yan

The use of laser desorption as a sample introduction method for solid phase microextraction (SPME) has been investigated in this research project. Three different types of analytical instruments,...

Laser Desorption Solid Phase Microextraction (2006)

Wang, Yan

The use of laser desorption as a sample introduction method for solid phase microextraction (SPME) has been investigated in this research project. Three different types of analytical instruments,...

Multipattern Consensus Regions in Multiple Aligned Protein Sequences and Their Segmentation (2006)

Yan Wang

Decomposing a biological sequence into its functional regions is an important prerequisite to understand the molecule. Using the multiple alignments of the sequences, we evaluate a segmentation based...

Trust and risk evaluation of transactions with different amounts in peer-to-peer e-commerce environments (2006)

Wang, Yan, Lin, Fu-ren

As peer-to-peer (P2P) e-commerce environments lack central management, prior to new transactions with an unknown peer, the trust evaluation becomes a very important concern, which relies on the...

DynamicTrust : the trust development in peer-to-peer environments (2006)

Wang, Yan, Varadharajan, Vijay

In peer-to-peer (P2P) environment, trust is a very important issue when transactions/interactions occur between peers. In general, the trust evaluation on transactions/interactions relies on the...

Trust and risk evaluation of transactions with different amounts in peer-to-peer e-commerce environments (2006)

Wang, Yan, Lin, Fu-ren

As peer-to-peer (P2P) e-commerce environments lack central management, prior to new transactions with an unknown peer, the trust evaluation becomes a very important concern, which relies on the...

DynamicTrust : the trust development in peer-to-peer environments (2006)

Wang, Yan, Varadharajan, Vijay

In peer-to-peer (P2P) environment, trust is a very important issue when transactions/interactions occur between peers. In general, the trust evaluation on transactions/interactions relies on the...

Trust and risk evaluation of transactions with different amounts in peer-to-peer e-commerce environments (2006)

Wang, Yan, Lin, Fu-ren

As peer-to-peer (P2P) e-commerce environments lack central management, prior to new transactions with an unknown peer, the trust evaluation becomes a very important concern, which relies on the...

DynamicTrust : the trust development in peer-to-peer environments (2006)

Wang, Yan, Varadharajan, Vijay

In peer-to-peer (P2P) environment, trust is a very important issue when transactions/interactions occur between peers. In general, the trust evaluation on transactions/interactions relies on the...

Semantic tolerance modeling – An overview (2006)

Yan Wang

A significant amount of research efforts has been given to explore the mathematical basis for 3D dimensional and geometric tolerance representation, analysis, and synthesis. However, engineering...

Nonclassical symmetries and group invariant solutions of Burgers-Fisher equations ∗ (2006)

Guoliang Cai, Yan Wang, Fengyun Zhang

Abstract. In this paper, the symmetries and group invariant solutions of Burgers-Fisher equation are obtained by using the nonclassical method. Keywords: Burgers-Fisher equation, nonclassical method,...

Multipattern Consensus Regions in Multiple Aligned Protein Sequences and Their Segmentation (2006)

Yan Wang

Decomposing a biological sequence into its functional regions is an important prerequisite to understand the molecule. Using the multiple alignments of the sequences, we evaluate a segmentation based...

Identification of surface-exposed components of MOMP of Chlamydia trachomatis serovar F (2006)

Wang, Yan, Berg, Eric A., Feng, Xiaogeng, Shen, Li, Smith, Temple, Costello, Catherine E., ...

The identification of surface-exposed components of the major outer membrane protein (MOMP) of Chlamydia is critical for modeling its three-dimensional structure, as well as for understanding the...

Attributable risk function in the proportional hazards model for censored time-to-event (2006)

Chen, Ying Qing, Hu, Chengcheng, Wang, Yan

Time-to-event endpoints are often used in clinical and epidemiological studies to evaluate disease association with hazardous exposures. In the statistical literature of time-to-event analysis, such...

Attributable risk function in the proportional hazards model for censored time-to-event (2006)

Chen, Ying Qing, Hu, Chengcheng, Wang, Yan

Time-to-event endpoints are often used in clinical and epidemiological studies to evaluate disease association with hazardous exposures. In the statistical literature of time-to-event analysis, such...

Laser Desorption Solid Phase Microextraction (2006)

Wang, Yan

The use of laser desorption as a sample introduction method for solid phase microextraction (SPME) has been investigated in this research project. Three different types of analytical instruments,...

Respiratory Viruses Augment the Adhesion of Bacterial Pathogens to Respiratory Epithelium in a Viral Species- and Cell Type-Dependent Manner (2006)

Avadhanula, Vasanthi, Rodriguez, Carina A., DeVincenzo, John P., Wang, Yan, Webby, Richard J., Ulett, Glen Charles, ...

Secondary bacterial infections often complicate respiratory viral infections, but the mechanisms whereby viruses predispose to bacterial disease are not completely understood. We determined the...

Respiratory Viruses Augment the Adhesion of Bacterial Pathogens to Respiratory Epithelium in a Viral Species- and Cell Type-Dependent Manner (2006)

Avadhanula, Vasanthi, Rodriguez, Carina A., DeVincenzo, John P., Wang, Yan, Webby, Richard J., Ulett, Glen Charles, ...

Secondary bacterial infections often complicate respiratory viral infections, but the mechanisms whereby viruses predispose to bacterial disease are not completely understood. We determined the...

High resolution genomic analysis of sporadic breast cancer using array-based comparative genomic hybridization (2005)

Naylor, Tara L, Greshock, Joel, Wang, Yan, Colligon, Theresa, Yu, QC, Clemmer, Virginia, ...

Abstract Introduction Genomic aberrations in the form of subchromosomal DNA copy number changes are a hallmark of epithelial cancers, including breast cancer. The goal of the present study was to...

A Fine-Scale Linkage Disequilibrium Measure Based on Length of Haplotype Sharing (2005)

Wang, Yan, Zhao, Lue Ping, Dudoit, Sandrine

High-throughput genotyping technologies for single nucleotide polymorphisms (SNP) have enabled the recent completion of the International HapMap Project (Phase I), which has stimulated much interest...

A Fine-Scale Linkage Disequilibrium Measure Based on Length of Haplotype Sharing (2005)

Wang, Yan, Zhao, Lue Ping, Dudoit, Sandrine

High-throughput genotyping technologies for single nucleotide polymorphisms (SNP) have enabled the recent completion of the International HapMap Project (Phase I), which has stimulated much interest...

A Fine-Scale Linkage Disequilibrium Measure Based on Length of Haplotype Sharing (2005)

Wang, Yan, Zhao, Lue Ping, Dudoit, Sandrine

High-throughput genotyping technologies for single nucleotide polymorphisms (SNP) have enabled the recent completion of the International HapMap Project (Phase I), which has stimulated much interest...

A Fine-Scale Linkage Disequilibrium Measure Based on Length of Haplotype Sharing (2005)

Wang, Yan, Zhao, Lue Ping, Dudoit, Sandrine

High-throughput genotyping technologies for single nucleotide polymorphisms (SNP) have enabled the recent completion of the International HapMap Project (Phase I), which has stimulated much interest...

Linear Regression of Censored Length-biased Lifetimes (2005)

Chen, Ying Qing, Wang, Yan

Length-biased lifetimes may be collected in observational studies or sample surveys due to biased sampling scheme. In this article, we use a linear regression model, namely, the accelerated failure...

Linear Regression of Censored Length-biased Lifetimes (2005)

Chen, Ying Qing, Wang, Yan

Length-biased lifetimes may be collected in observational studies or sample surveys due to biased sampling scheme. In this article, we use a linear regression model, namely, the accelerated failure...

Linear Regression of Censored Length-biased Lifetimes (2005)

Chen, Ying Qing, Wang, Yan

Length-biased lifetimes may be collected in observational studies or sample surveys due to biased sampling scheme. In this article, we use a linear regression model, namely, the accelerated failure...

Linear Regression of Censored Length-biased Lifetimes (2005)

Chen, Ying Qing, Wang, Yan

Length-biased lifetimes may be collected in observational studies or sample surveys due to biased sampling scheme. In this article, we use a linear regression model, namely, the accelerated failure...

Attributable Risk Function in the Proportional Hazards Model (2005)

Chen, Ying Qing, Hu, Chengcheng, Wang, Yan

As an epidemiological parameter, the population attributable fraction is an important measure to quantify the public health attributable risk of an exposure to morbidity and mortality. In this...

Attributable Risk Function in the Proportional Hazards Model (2005)

Chen, Ying Qing, Hu, Chengcheng, Wang, Yan

As an epidemiological parameter, the population attributable fraction is an important measure to quantify the public health attributable risk of an exposure to morbidity and mortality. In this...

Attributable Risk Function in the Proportional Hazards Model (2005)

Chen, Ying Qing, Hu, Chengcheng, Wang, Yan

As an epidemiological parameter, the population attributable fraction is an important measure to quantify the public health attributable risk of an exposure to morbidity and mortality. In this...

Attributable Risk Function in the Proportional Hazards Model (2005)

Chen, Ying Qing, Hu, Chengcheng, Wang, Yan

As an epidemiological parameter, the population attributable fraction is an important measure to quantify the public health attributable risk of an exposure to morbidity and mortality. In this...

Symmetric multiparty-controlled teleportation of an arbitrary two-particle entanglement (2005)

Deng, Fu-Guo, Li, Chun-Yan, Li, Yan-Song, Zhou, Hong-Yu, Wang, Yan

We present a way for symmetric multiparty-controlled teleportation of an arbitrary two-particle entangled state based on Bell-basis measurements by using two Greenberger-Horne-Zeilinger states, i.e.,...

Emissions trading and the aviation industry: A case study of Britannia Airways under the EU emissions trading scheme (2005)

Wang, Yan

This thesis is submitted in partial fulfilment of the requirements for the degree of Master of Science. The thesis sets out the results of a structured programme of research or design, development or...

Acquisition numbers and competition acquisition numbers : a dissertation / (2005)

Wang, Yan.

Thesis (Ph.D.) -- University of Alabama in Huntsville, 2005.

Applying Drop-On-Demand inkjet printing method to maskless lithography / (2005)

Wang, Yan.

Thesis (Ph.D. in Engineering-Electrical Engineering and Computer Sciences)--University of California, Berkeley, Fall 2005.

Towards autonomous and automatic evaluation and negotiation in agent-mediated internet marketplaces (2005)

Wang, Yan, Tan, Kian-Lee, Ren, Jian

In an agent-mediated B2C Internet marketplace, agents, mobile or stationary, can act on behalf of customers to complete tasks involved in buying and selling products. In this paper, we first present...

Receivers and CQI Measures for MIMO-CDMA Systems in Frequency-Selective Channels (2005)

Jianzhong (Charlie) Zhang, Balaji Raghothaman, Yan Wang, Giridhar Mandyam

We investigate receiver designs and CQI (channel quality indicator) measures for the jointly encoded (JE) and separately encoded (SE) types of MIMO transmission. For the JE transmission, we develop a...

Towards autonomous and automatic evaluation and negotiation in agent-mediated internet marketplaces (2005)

Wang, Yan, Tan, Kian-Lee, Ren, Jian

In an agent-mediated B2C Internet marketplace, agents, mobile or stationary, can act on behalf of customers to complete tasks involved in buying and selling products. In this paper, we first present...

Trust² : developing trust in peer-to-peer environments (2005)

Wang, Yan, Varadharajan, Vijay

In peer-to-peer (P2P) environments, a peer needs to interact with unknown peers for the services provided. This requires the trust evaluation prior to and posterior to interactions. This paper...

Trust² : developing trust in peer-to-peer environments (2005)

Wang, Yan, Varadharajan, Vijay

In peer-to-peer (P2P) environments, a peer needs to interact with unknown peers for the services provided. This requires the trust evaluation prior to and posterior to interactions. This paper...

Towards autonomous and automatic evaluation and negotiation in agent-mediated internet marketplaces (2005)

Wang, Yan, Tan, Kian-Lee, Ren, Jian

In an agent-mediated B2C Internet marketplace, agents, mobile or stationary, can act on behalf of customers to complete tasks involved in buying and selling products. In this paper, we first present...

Trust² : developing trust in peer-to-peer environments (2005)

Wang, Yan, Varadharajan, Vijay

In peer-to-peer (P2P) environments, a peer needs to interact with unknown peers for the services provided. This requires the trust evaluation prior to and posterior to interactions. This paper...

Simulating the Long-term Effects of China’s Expansionary Fiscal Policy in an overlapping generations model (2005)

Shuanglin Lin, Yan Wang, Fan Zhai

China’s public debt has risen rapidly since the adoption of expansionary fiscal policies seven years ago. This paper simulates the effects of China’s expansionary fiscal policy in a computable...

Receivers and CQI Measures for MIMO-CDMA Systems in Frequency-Selective Channels (2005)

Jianzhong (Charlie) Zhang, Balaji Raghothaman, Yan Wang, Giridhar Mandyam

We investigate receiver designs and CQI (channel quality indicator) measures for the jointly encoded (JE) and separately encoded (SE) types of MIMO transmission. For the JE transmission, we develop a...

Gravity Signal Transduction in Primary Roots (2005)

PERRIN, ROBYN M., YOUNG, LI-SEN, U. M., NARAYANA MURTHY, HARRISON, BENJAMIN R., WANG, YAN, WILL, JESSICA L., ...

• Aims The molecular mechanisms that correlate with gravity perception and signal transduction in the tip of angiosperm primary roots are discussed. • Scope Gravity provides a cue for downward...

Gravity Signal Transduction in Primary Roots (2005)

PERRIN, ROBYN M., YOUNG, LI-SEN, NARAYANA MURTHY, U.M., HARRISON, BENJAMIN R., WANG, YAN, WILL, JESSICA L., ...

• Aims The molecular mechanisms that correlate with gravity perception and signal transduction in the tip of angiosperm primary roots are discussed. • Scope Gravity provides a cue for downward...

Structure-Activity Relationship of Polyphenols That Inhibit Fatty Acid Synthase (2005)

Li, Bing-Hui, Ma, Xiao-Feng, Wang, Yan, Tian, Wei-Xi

Many flavone derivatives inhibit FAS, and their A and B rings play an important role, but is the C ring necessary for the inhibition of FAS? Here, using nordihydroguaiaretic acid (NDGA), with two...

Gravity Signal Transduction in Primary Roots (2005)

PERRIN, ROBYN M., YOUNG, LI-SEN, U. M., NARAYANA MURTHY, HARRISON, BENJAMIN R., WANG, YAN, WILL, JESSICA L., ...

• Aims The molecular mechanisms that correlate with gravity perception and signal transduction in the tip of angiosperm primary roots are discussed. • Scope Gravity provides a cue for downward...

Prenatal Estrogen Exposure Differentially Affects Estrogen Receptor-Associated Proteins in Rat Testis Gonocytes1 (2004)

Yan Wang, Raphael Thuillier, Martine Culty

We previously reported that gonocytes from 3-day-old rat testes proliferate in response to estradiol. In the present study, we found that purified gonocytes contained the mRNAs of estrogen receptor...

Quantification and Visualization of LD Patterns and Identification of Haplotype Blocks (2004)

Wang, Yan, Dudoit, Sandrine

Classical measures of linkage disequilibrium (LD) between two loci, based only on the joint distribution of alleles at these loci, present noisy patterns. In this paper, we propose a new...

Quantification and Visualization of LD Patterns and Identification of Haplotype Blocks (2004)

Wang, Yan, Dudoit, Sandrine

Classical measures of linkage disequilibrium (LD) between two loci, based only on the joint distribution of alleles at these loci, present noisy patterns. In this paper, we propose a new...

Quantification and Visualization of LD Patterns and Identification of Haplotype Blocks (2004)

Wang, Yan, Dudoit, Sandrine

Classical measures of linkage disequilibrium (LD) between two loci, based only on the joint distribution of alleles at these loci, present noisy patterns. In this paper, we propose a new...

Quantification and Visualization of LD Patterns and Identification of Haplotype Blocks (2004)

Wang, Yan, Dudoit, Sandrine

Classical measures of linkage disequilibrium (LD) between two loci, based only on the joint distribution of alleles at these loci, present noisy patterns. In this paper, we propose a new...

Chromosome Walking in the Petunia Inflata Self-Incompatibility ( S -) Locus and Gene Identification in an 881-kb Contig Containing S 2 -RNase (2004)

Wang, Xi, Wang, Yan, Tsukamoto, Tatsuya, Yi, Ki-wan, Huang, Shihshieh, McCubbin, Andrew G., ...

Self-incompatibility (SI) in the Solanaceae, Rosaceae and Scrophulariaceae is controlled by the polymorphic S locus, which contains two separate genes encoding pollen and pistil determinants in SI...

Grayscale image matting and colorization (2004)

Tongbo Chen, Yan Wang, Volker Schillings, Christoph Meinel

Fig. 1. Grayscale image matting and colorization results. A and B are the input grayscale images to our algorithm, while A ′

A Dynamic Two-Phase Commit Protocol for Self-Adapting Services (2004)

Weihai Yu, Yan Wang

Next-generation applications based on Web services impose additional requirements on the use of coordination protocols with various optimizations, such as the two-phase commit protocol (2PC). This...

Maskless Lithography Using Drop-On-Demand Inkjet Printing Method,” Emerging Lithographic Technologies (2004)

Yan Wang, Jeffrey Bokor, Arthur Lee

Writing process patterns directly on a substrate with small liquid droplets generated by Drop-On-Demand (DOD) inkjet devices offers a low cost, non-contact, low temperature, flexible, and data driven...

Downloaded from physiolgenomics.physiology.org (2004)

Makoto Kano, Shuichi Tsutsumi, Nobutaka Kawahara, Yan Wang, Takaaki Kirino, Hiroyuki Aburatani, ...

doi:10.1152/physiolgenomics.00107.2004 You might find this additional information useful... Supplemental material for this article can be found at:

Three-Dimensional Culture of Hybridoma Cells Secreting Anti-Human Chorionic Gonadotropin by a New Rolling Culture System (2004)

Yan Wang, Hong-Li Jiao, Jin-Zhu Zhang, Rong-Qiao He

Cell growth rate and production of monoclonal antibody (MAb) of hybridoma cells producing anti-human chorionic gonadotropin (hCG) MAb have been used as investigation criteria in double-mouthed...

A novel strategy to engineer DNA polymerases for enhanced processivity and improved performance in vitro (2004)

Wang, Yan, Prosen, Dennis E., Mei, Li, Sullivan, John C., Finney, Michael, Vander Horn, Peter B.

Mechanisms that allow replicative DNA polymerases to attain high processivity are often specific to a given polymerase and cannot be generalized to others. Here we report a protein...

Genetic mapping and molecular characterization of the self-incompatibility ( S ) locus in Petunia inflata (2003)

Kao, Teh-hui, Wang, Yan, Wang, Xi, McCubbin, Andrew G.

Gametophytic self-incompatibility (SI) possessed by the Solanaceae is controlled by a highly polymorphic locus called the S locus. The S locus contains two linked genes, S-RNase , which determines...

Progress in the development of a recombinant vaccine for human hookworm disease: The Human Hookworm Vaccine Initiative (2003)

Hotez, Peter J., Zhan, Bin, Bethony, Jeffrey M., Loukas, Alex, Williamson, Angela, Goud, Gaddam Narsa, ...

Hookworm infection is one of the most important parasitic infections of humans, possibly outranked only by malaria as a cause of misery and suffering. An estimated 1.2 billion people are infected...

Constraint-Enabled Design Information Representation for Mechanical Products Over the Internet (2003)

Wang, Yan

Global economy has made manufacturing industry become more distributed than ever before. Product design requires more involvement from various technical disciplines at different locations. In such a...

Constraint-Enabled Design Information Representation for Mechanical Products Over the Internet (2003)

Wang, Yan

Global economy has made manufacturing industry become more distributed than ever before. Product design requires more involvement from various technical disciplines at different locations. In such a...

Prenatal Exposure to Estrogenic Compounds Alters the Expression Pattern of Platelet-Derived Growth Factor Receptors α and β in Neonatal Rat Testis: Identification of Gonocytes as Targets of Estrogen Exposure1 (2003)

Raphael Thuillier, Yan Wang, Martine Culty

We examined the effects of maternal exposure to estrogens on platelet-derived growth factor (PDGF) receptor (PDGFR) expression in newborn rat testis. Pregnant rats were treated from gestation Day 14...

Integration eines Workflow-Systems in das Grid (2003)

Wang, Yan

Die Kernidee von Grid-Computing ist, einen Pool von Computern zu einervirtuellen Computingeinheit zusammenzufuegen. Anforderungen von Anwendungen anComputing-Resourcen werden dynamisch aus diesem...

Low power design for wireless communication system / (2003)

Wang, Yan.

Thesis (Ph. D.)--Hong Kong University of Science and Technology, 2003.

Low power design for wireless communication system (2003)

Wang, Yan

Thesis (Ph.D.)--Hong Kong University of Science and Technology, 2003

Social responsibility and intellectual development as outcomes of service-learning courses (2003)

Wang, Yan

This study focuses the following: (1) the development of social responsibility and intellectual complexity as outcomes of service-learning courses, (2) the relationship between these two outcomes,...

Integration eines Workflow-Systems in das Grid (2003)

Wang, Yan

Die Kernidee von Grid-Computing ist, einen Pool von Computern zu einer virtuellen Computingeinheit zusammenzufuegen. Anforderungen von Anwendungen an Computing-Resourcen werden dynamisch aus diesem...

Low power design for wireless communication system / (2003)

Wang, Yan.

Thesis (Ph. D.)--Hong Kong University of Science and Technology, 2003.

The fast neural networks digital beamformer based on slow genetic algorithm solutions / (2003)

Wang, Yan.

Thesis (M. Eng.)--Nanyang Technological University, School of Electrical and Electronic Engineering, 2003.

Low power design for wireless communication system / (2003)

Wang, Yan.

Thesis (Ph. D.)--Hong Kong University of Science and Technology, 2003.

Mobile Networks and Applications 8, 413--423, 2003 (2003)

Security And Robustness, Yan Wang, Xiaolin Pang

In this paper, we present a parallel dispatch model with secure route structures for protecting the dispatch route information of mobile agents. This model facilitates efficient dispatching of agents...

A secure agent-mediated payment protocol (2002)

Xiaolin Pang, Yan Wang, Jian Ren

Abstract. While software agents have been employed in payment protocols, they are largely passive entities, i.e., they participate in the payment protocol but do not make decision. In this paper, we...

Modelica Applications for Camless Engine Valvetrain Development (2002)

Christopher Puchalsky, Thomas Megli, Michael Tiller, Nate Trask, Yan Wang, Eric Curtis

Several variable valvetrain technologies are being aggressively pursued to increase vehicle fuel economy and reduce engine exhaust emission levels. Electromechanical Valve Actuation (EMVA) is a...

A Study of Building Internet Marketplaces on the Basis of Mobile Agents for Parallel Processing (2002)

Yan Wang, Jian Ren

In this paper, we propose a framework of Internet marketplaces on the basis of mobile agent. It not only simulates real commercial activities by consumers, agents and merchants, but also provides an...

Image-based indexing and retrieval of trademark logos / (2002)

Wang, Yan.

Thesis (M. Eng.)--Nanyang Technological University, School of Computer Engineering, 2002.

The Role of the Homeobox Gene ATHB16 in Development Regulation in Arabidopsis thaliana (2001)

Wang, Yan

There are 42 members of the homeodomain-leucine zipper (HDZip) family of transcription factors in Arabidopsis thaliana. This thesis focuses on the functional analysis of one member of this family,...

The Role of the Homeobox Gene ATHB16 in Development Regulation in Arabidopsis thaliana (2001)

Wang, Yan

There are 42 members of the homeodomain-leucine zipper (HDZip) family of transcription factors in Arabidopsis thaliana. This thesis focuses on the functional analysis of one member of this family,...

Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication (2001)

Wang, Yan, Michikawa, Yuichi, Mallidis, Con, Bai, Yan, Woodhouse, Linda, Yarasheski, Kevin E., ...

The recently discovered aging-dependent large accumulation of point mutations in the human fibroblast mtDNA control region raised the question of their occurrence in postmitotic tissues. In the...

Design and creation of e-commerce website for Count-on-us Ltd / (2001)

Wang, Yan.

Thesis (M. Sc.)--University of Leeds (School of Computing), 2001.

Camless engine valvetrain : enabling technology and control techniques / (2001)

Wang, Yan.

Thesis (Ph. D.)--University of California, Santa Barbara, 2001.

Design and creation of e-commerce website for Count-on-us Ltd / (2001)

Wang, Yan.

Thesis (M. Sc.)--University of Leeds (School of Computing), 2001.

2001. “Sources of China’s Economic Growth. 1952–99: Incorporating Human Capital Accumulation (2001)

Yan Wang, Yan Wang, Yudong Yao, Yudong Yao

China’s performance in economic growth and poverty reduction has been remarkable. There is an on-going debate about whether this growth is mainly driven by productivity or factor accumulation. Few...

Implicit Pension Debt, Transition Cost, Options and Impact of China’s Pension Reform: A computable General Equilibrium Analysis.” Policy Research Working Paper 2555. The World (2001)

Yan Wang, Dianqing Xu, Zhi Wang, Fan Zhai, Louise Fox, E. C. Hwa, ...

for comments and suggestions; as well as to participants at a NBER-CCER seminar held in July 1999, and a World Bank-MOF seminar on Managing Fiscal Risk held on June 12-15, 2000. Support from the...

Design and creation of e-commerce website for Count-on-us Ltd / (2001)

Wang, Yan.

Thesis (M. Sc.)--University of Leeds (School of Computing), 2001.

Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis (2001)

Wang, Yan, Tan, Jenny, Sutton-Smith, Mark, Ditto, David, Panico, Maria, Campbell, Robert M., ...

The congenital disorders of glycosylation (CDGs) are recent additions to the repertoire of inherited human genetic diseases. Frequency of CDGs is unknown since most cases are believed to be...

Signaling pathways for regulation ofc-fos expression and the ER stress response (2000)

Wang, Yan

In order to understand the transcriptional regulation of c-fos, the pathways for induction of the c-fos promoter by serum, EGF (epidermal growth factor) and TPA (12-O-tetradecanoyl phorbol-13...

A liquid chromatography-mass spectrometry method for the quantification of bioavailability and bioconversion of beta-carotene to retinol in humans (2000)

Yan Wang, Xiaoying Xu, West, C.E., Lugtenburg, J., Verhoeven, M.A., ...

A method based on high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry (APCI LC-MS) was developed for the quantification of the bioavailability of retinyl...

Networked collaborative design / (2000)

Wang, Yan.

These (M.Eng.)--Nanyang Technological University, School of Mechanical and Production Engineering, 2000.

ThesisPR (2000)

Wang, Yan

Department: Biological Sciences.

Lactation Reduces Breast Cancer Risk in Shandong Province, China (2000)

Zheng, Tongzhang, Duan, Li, Liu, Yi, Zhang, Bing, Wang, Yan, Chen, Yongxiang, ...

Results from studies of western populations investigating lactation and breast cancer risk have been inconsistent. To examine this issue, the authors conducted a hospital-based case-control study in...

Automated variational method for computer vision [microform] / (1999)

Wang, Yan.

Thesis (M.S.)--University of Kansas, Electrical Engineering and Computer Science, 1999.

Automatic Target Recognition with Dynamic Reconfiguration (1999)

Jack Jean, Xuejun Liang, Brian Drozd, Karen Tomko, Yan Wang

. This paper describes the acceleration of an infrared automatic target recognition (IR ATR) application with a co-processor board that contains multiple field programmable gate array (FPGA) chips....

The power of women : a comparison of two Latin American novels / (1998)

Wang, Yan.

Thesis (M.A.)--Midwestern State University, Wichita Falls, Tex., 1998.

The identification of agouti gene exon 2 in porcine genomic DNA /--by Yan Wang. (1997)

Wang, Yan.

Thesis (M.S.)--Biology and Microbiology Dept., South Dakota State University, 1997.

An Application Concept of an Underwater Robot Society (1996)

Mika Vainio, Aarne Halme, Pekka Appelqvist, Pekka Kähkönen, Peter Jakubik, Torsten Schönberg, ...

Cooperation as a mean to adapt to dynamic environments is well known in animal world from the social insects up to primates. But similar behavior seems to exist also in simple unicellular microbes....

Motion Control Of A Spherical Mobile Robot (1996)

Aarne Halme, Torsten Schönberg, Yan Wang

: The paper deals with dynamics and control of a special type of mobile robot designed to act as a small platform to carry sensing devices or actuators in an environment where stability of the...

Serologic Association Between Human Papillomavirus Type 16 Infection and Esophageal Cancer in Shaanxi Province, China (1996)

Han, Chenglong, Qiao, Guibin, Hubbert, Nancy L., Li, Liangshou, Sun, Changsheng, Wang, Yan, ...

Background: The existence of large geographic variations in the prevalence of esophageal cancer in some countries, such as China, indicates that environmental risk factors may be important in the...

Laser confocal immunofluorescent studies of Troponin T in embryonic hearts of normal and cardiac mutant axolotls /--Yan Wang (1995)

Wang, Yan

Ph. D. dissertation -- State University of New York, Health Science Center at Syracuse, 1995

Effect of an ATP sensitive potassium channel opener, levcromakalim, on coronary arterial microvessels in the beating canine heart (1994)

Sato, Kouichi, Kanatsuka, Hiroshi, Sekiguchi, Nobuyo, Akai, Kenjiro, Wang, Yan, Sugimura, Akihiko, ...

Objective: The aim was to clarify the site in the coronary microcirculation that is dilated by an ATP sensitive potassium channel opener, levcromakalim, and to examine whether the magnitude of...

Optimal hydropower generation scheduling for a cascade (1993)

BROUGHAN, KEVIN, MCKENZIE, CAROLYN, SNEYD, ALFRED, WANG, YAN

This paper presents a method for short-term generation scheduling in a multiplereservoir river system. The reservoir dynamics are described using the network flow balance equations, taking into...

Effects of {alpha} and {beta} adrenergic blockade on coronary arterial microvessels in the beating canine heart (1992)

Sekiguchi, Nobuyo, Kanatsuka, Hiroshi, Komaru, Tatsuya, Akai, Kenjiro, Sato, Kouichi, Wang, Yan, ...

Objective: The aim was to clarify the effects of and β adrenergic blockade on coronary arterial microvessels and to assess the role of and β adrenergic tone in normally beating hearts. Methods:...

Inequality and Poverty in China: Institutional Change and Public Policy, 1978 to 1988 (1991)

Ahmad, Ehtisham, Wang, Yan

There is considerable uncertainty and debate about changes in poverty and living standards that are likely to occur in an economy in transition from centrally planned allocations to a more...

Analysis of Mobile Commerce Value Chain (1970)

Yan Wang, Tingjie Lu

The opportunities offered by the Internet have already fuelled immense growth of E-commerce. In recent years, due to the rapid evolution of wireless and mobile communication technologies, mobile...

Secure Production of Farm Produce-oriented Management and Spatial Decision-making System for Producing Area (1970)

Yan Wang, Yuchun Pan, Bojie Yan, Anyun Li, Jihua Wang

To address security of farm produces quality, using object-oriented technologies to build multi-purpose database, it meets the current and future data needs of a variety of operational systems....

Measuring education inequality - Gini coefficients of education

Thomas, Vinod, Wang, Yan, Fan, Xibo

The authors use a Gini index to measure inequality in educational attainment. They present two methods (direct and indirect) for calculating an education Gini index, and generate a quinquennial data...

Brain drain or brain gain: A revisit

Donald Lien, Yan Wang

Recent literature has turned to the brain gain effect, instead of the brain drain effect, that emigration may bring to a source country. This paper, however, suggests brain drain remains a likely...

Sources of China's economic growth, 1952-99 : incorporating human capital accumulation

Yan Wang, Yudong Yao

China's performance in economic growth, and poverty reduction has been remarkable. There is an ongoing debate about whether this growth is mainly driven by productivity, or factor accumulation. But...

Social responsibility and intellectual development as outcomes of service-learning courses

Wang, Yan

This study focuses the following: (1) the development of social responsibility and intellectual complexity as outcomes of service-learning courses, (2) the relationship between these two outcomes,...

Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication

Wang, Yan, Michikawa, Yuichi, Mallidis, Con, Bai, Yan, Woodhouse, Linda, Yarasheski, Kevin E., ...

The recently discovered aging-dependent large accumulation of point mutations in the human fibroblast mtDNA control region raised the question of their occurrence in postmitotic tissues. In the...

Baculovirus p33 Binds Human p53 and Enhances p53-Mediated Apoptosis

Prikhod’ko, Grigori G., Wang, Yan, Freulich, Ella, Prives, Carol, Miller, Lois K.

In vertebrates, p53 participates in numerous biological processes including cell cycle regulation, apoptosis, differentiation, and oncogenic transformation. When insect SF-21 cells were infected with...

Identification and Topological Arrangement of Drosophila Proximal Sequence Element (PSE)-Binding Protein Subunits That Contact the PSEs of U1 and U6 Small Nuclear RNA Genes

Wang, Yan, Stumph, William E.

Most small nuclear RNAs (snRNAs) are synthesized by RNA polymerase II, but U6 and a few others are synthesized by RNA polymerase III. Transcription of snRNA genes by either polymerase is dependent on...

Limited Genetic Diversity of Recent Invasive Isolates of Non-Serotype b Encapsulated Haemophilus influenzae

Omikunle, Adebomi, Takahashi, Shinji, Ogilvie, Chrishana L., Wang, Yan, Rodriguez, Carina A., St. Geme, Joseph W., ...

Invasive infections caused by non-type b encapsulated Haemophilus influenzae have increased in frequency in the last decade. This change prompted us to characterize the genetic relationships of 48...

Kaposi's Sarcoma-Associated Herpesvirus Lytic Origin (ori-Lyt)-Dependent DNA Replication: Identification of the ori-Lyt and Association of K8 bZip Protein with the Origin

Lin, Cui Li, Li, Hong, Wang, Yan, Zhu, Fan Xiu, Kudchodkar, Sagar, Yuan, Yan

Herpesviruses utilize different origins of replication during lytic versus latent infection. Latent DNA replication depends on host cellular DNA replication machinery, whereas lytic cycle DNA...

Subtractive Hybridization Identifies a Novel Predicted Protein Mediating Epithelial Cell Invasion by Virulent Serotype III Group B Streptococcus agalactiae

Adderson, Elisabeth E., Takahashi, Shinji, Wang, Yan, Armstrong, Jianling, Miller, Dylan V., Bohnsack, John F.

Group B Streptococcus agalactiae bacteria (group B streptococci [GBS]) are the most common cause of serious bacterial infection in newborn infants. The majority of serotype III-related cases of...

A novel strategy to engineer DNA polymerases for enhanced processivity and improved performance in vitro

Wang, Yan, Prosen, Dennis E., Mei, Li, Sullivan, John C., Finney, Michael, Vander Horn, Peter B.

Mechanisms that allow replicative DNA polymerases to attain high processivity are often specific to a given polymerase and cannot be generalized to others. Here we report a protein engineering-based...

Kaposi's Sarcoma-Associated Herpesvirus ori-Lyt-Dependent DNA Replication: cis-Acting Requirements for Replication and ori-Lyt-Associated RNA Transcription

Wang, Yan, Li, Hong, Chan, Man Yee, Zhu, Fan Xiu, Lukac, David M., Yuan, Yan

Herpesvirus lytic DNA replication requires both the cis-acting element, the origin, and trans-acting factors such as virally encoded origin-binding protein and DNA replication enzymes. Recently, the...

Impaired up-regulation of CD25 on CD4+ T cells in IFN-γ knockout mice is associated with progression of myocarditis to heart failure

Afanasyeva, Marina, Georgakopoulos, Dimitrios, Belardi, Diego F., Bedja, Djahida, Fairweather, DeLisa, Wang, Yan, ...

Inflammation has been recognized increasingly as a critical pathologic component of a number of heart diseases. A mouse model of autoimmune myocarditis was developed to study the role of immune...

Three-Dimensional Culture of Hybridoma Cells Secreting Anti-Human Chorionic Gonadotropin by a New Rolling Culture System

Wang, Yan, Jiao, Hong-Li, Zhang, Jin-Zhu, He, Rong-Qiao

Cell growth rate and production of monoclonal antibody (MAb) of hybridoma cells producing anti-human chorionic gonadotropin (hCG) MAb have been used as investigation criteria in double-mouthed...

Transcriptional regulation of phagocytosis-induced membrane biogenesis by sterol regulatory element binding proteins

Castoreno, Adam B., Wang, Yan, Stockinger, Walter, Jarzylo, Larissa A., Du, Hong, Pagnon, Joanne C., ...

In the process of membrane biogenesis several dozen proteins must operate in precise concert to generate ≈100 lipids at appropriate concentrations. To study the regulation of bilayer assembly in a...

Biochemical Characterization and Vaccine Potential of a Heme-Binding Glutathione Transferase from the Adult Hookworm Ancylostoma caninum

Zhan, Bin, Liu, Sen, Perally, Samirah, Xue, Jian, Fujiwara, Ricardo, Brophy, Peter, ...

We report the cloning and expression of Ac-GST-1, a novel glutathione S-transferase from the adult hookworm Ancylostoma caninum, and its possible role in parasite blood feeding and as a vaccine...

A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3β/FBW7 loss of function

Rottmann, Sabine, Wang, Yan, Nasoff, Marc, Deveraux, Quinn L., Quon, Kim C.

The MYC protooncogene is frequently deregulated in human cancers. Here, by screening a kinase-directed library of small inhibitory RNAs, we identify glycogen synthase kinase 3β (GSK3β) as a gene...

Respiratory Viruses Augment the Adhesion of Bacterial Pathogens to Respiratory Epithelium in a Viral Species- and Cell Type-Dependent Manner

Avadhanula, Vasanthi, Rodriguez, Carina A., DeVincenzo, John P., Wang, Yan, Webby, Richard J., Ulett, Glen C., ...

Secondary bacterial infections often complicate respiratory viral infections, but the mechanisms whereby viruses predispose to bacterial disease are not completely understood. We determined the...

Gene expression profiling differentiates germ cell tumors from other cancers and defines subtype-specific signatures

Juric, Dejan, Sale, Sanja, Hromas, Robert A., Yu, Ron, Wang, Yan, Duran, George E., ...

Germ cell tumors (GCTs) of the testis are the predominant cancer among young men. We analyzed gene expression profiles of 50 GCTs of various subtypes, and we compared them with 443 other common...

A Fine-Scale Linkage-Disequilibrium Measure Based on Length of Haplotype Sharing

Wang, Yan, Zhao, Lue Ping, Dudoit, Sandrine

High-throughput genotyping technologies for SNPs have enabled the recent completion of the International HapMap Project (phase I), which has stimulated much interest in studying genomewide...

Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication

Wang, Yan, Michikawa, Yuichi, Mallidis, Con, Bai, Yan, Woodhouse, Linda, Yarasheski, Kevin E., ...

The recently discovered aging-dependent large accumulation of point mutations in the human fibroblast mtDNA control region raised the question of their occurrence in postmitotic tissues. In the...

Baculovirus p33 Binds Human p53 and Enhances p53-Mediated Apoptosis

Prikhod’ko, Grigori G., Wang, Yan, Freulich, Ella, Prives, Carol, Miller, Lois K.

In vertebrates, p53 participates in numerous biological processes including cell cycle regulation, apoptosis, differentiation, and oncogenic transformation. When insect SF-21 cells were infected with...

Identification and Topological Arrangement of Drosophila Proximal Sequence Element (PSE)-Binding Protein Subunits That Contact the PSEs of U1 and U6 Small Nuclear RNA Genes

Wang, Yan, Stumph, William E.

Most small nuclear RNAs (snRNAs) are synthesized by RNA polymerase II, but U6 and a few others are synthesized by RNA polymerase III. Transcription of snRNA genes by either polymerase is dependent on...

Limited Genetic Diversity of Recent Invasive Isolates of Non-Serotype b Encapsulated Haemophilus influenzae

Omikunle, Adebomi, Takahashi, Shinji, Ogilvie, Chrishana L., Wang, Yan, Rodriguez, Carina A., St. Geme, Joseph W., ...

Invasive infections caused by non-type b encapsulated Haemophilus influenzae have increased in frequency in the last decade. This change prompted us to characterize the genetic relationships of 48...

Kaposi's Sarcoma-Associated Herpesvirus Lytic Origin (ori-Lyt)-Dependent DNA Replication: Identification of the ori-Lyt and Association of K8 bZip Protein with the Origin

Lin, Cui Li, Li, Hong, Wang, Yan, Zhu, Fan Xiu, Kudchodkar, Sagar, Yuan, Yan

Herpesviruses utilize different origins of replication during lytic versus latent infection. Latent DNA replication depends on host cellular DNA replication machinery, whereas lytic cycle DNA...

Subtractive Hybridization Identifies a Novel Predicted Protein Mediating Epithelial Cell Invasion by Virulent Serotype III Group B Streptococcus agalactiae

Adderson, Elisabeth E., Takahashi, Shinji, Wang, Yan, Armstrong, Jianling, Miller, Dylan V., Bohnsack, John F.

Group B Streptococcus agalactiae bacteria (group B streptococci [GBS]) are the most common cause of serious bacterial infection in newborn infants. The majority of serotype III-related cases of...

A novel strategy to engineer DNA polymerases for enhanced processivity and improved performance in vitro

Wang, Yan, Prosen, Dennis E., Mei, Li, Sullivan, John C., Finney, Michael, Vander Horn, Peter B.

Mechanisms that allow replicative DNA polymerases to attain high processivity are often specific to a given polymerase and cannot be generalized to others. Here we report a protein engineering-based...

Kaposi's Sarcoma-Associated Herpesvirus ori-Lyt-Dependent DNA Replication: cis-Acting Requirements for Replication and ori-Lyt-Associated RNA Transcription

Wang, Yan, Li, Hong, Chan, Man Yee, Zhu, Fan Xiu, Lukac, David M., Yuan, Yan

Herpesvirus lytic DNA replication requires both the cis-acting element, the origin, and trans-acting factors such as virally encoded origin-binding protein and DNA replication enzymes. Recently, the...

Impaired up-regulation of CD25 on CD4+ T cells in IFN-γ knockout mice is associated with progression of myocarditis to heart failure

Afanasyeva, Marina, Georgakopoulos, Dimitrios, Belardi, Diego F., Bedja, Djahida, Fairweather, DeLisa, Wang, Yan, ...

Inflammation has been recognized increasingly as a critical pathologic component of a number of heart diseases. A mouse model of autoimmune myocarditis was developed to study the role of immune...

Three-Dimensional Culture of Hybridoma Cells Secreting Anti-Human Chorionic Gonadotropin by a New Rolling Culture System

Wang, Yan, Jiao, Hong-Li, Zhang, Jin-Zhu, He, Rong-Qiao

Cell growth rate and production of monoclonal antibody (MAb) of hybridoma cells producing anti-human chorionic gonadotropin (hCG) MAb have been used as investigation criteria in double-mouthed...

Transcriptional regulation of phagocytosis-induced membrane biogenesis by sterol regulatory element binding proteins

Castoreno, Adam B., Wang, Yan, Stockinger, Walter, Jarzylo, Larissa A., Du, Hong, Pagnon, Joanne C., ...

In the process of membrane biogenesis several dozen proteins must operate in precise concert to generate ≈100 lipids at appropriate concentrations. To study the regulation of bilayer assembly in a...

Biochemical Characterization and Vaccine Potential of a Heme-Binding Glutathione Transferase from the Adult Hookworm Ancylostoma caninum

Zhan, Bin, Liu, Sen, Perally, Samirah, Xue, Jian, Fujiwara, Ricardo, Brophy, Peter, ...

We report the cloning and expression of Ac-GST-1, a novel glutathione S-transferase from the adult hookworm Ancylostoma caninum, and its possible role in parasite blood feeding and as a vaccine...

A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3β/FBW7 loss of function

Rottmann, Sabine, Wang, Yan, Nasoff, Marc, Deveraux, Quinn L., Quon, Kim C.

The MYC protooncogene is frequently deregulated in human cancers. Here, by screening a kinase-directed library of small inhibitory RNAs, we identify glycogen synthase kinase 3β (GSK3β) as a gene...

Gene expression profiling differentiates germ cell tumors from other cancers and defines subtype-specific signatures

Juric, Dejan, Sale, Sanja, Hromas, Robert A., Yu, Ron, Wang, Yan, Duran, George E., ...

Germ cell tumors (GCTs) of the testis are the predominant cancer among young men. We analyzed gene expression profiles of 50 GCTs of various subtypes, and we compared them with 443 other common...

Respiratory Viruses Augment the Adhesion of Bacterial Pathogens to Respiratory Epithelium in a Viral Species- and Cell Type-Dependent Manner

Avadhanula, Vasanthi, Rodriguez, Carina A., DeVincenzo, John P., Wang, Yan, Webby, Richard J., Ulett, Glen C., ...

Secondary bacterial infections often complicate respiratory viral infections, but the mechanisms whereby viruses predispose to bacterial disease are not completely understood. We determined the...

A Fine-Scale Linkage-Disequilibrium Measure Based on Length of Haplotype Sharing

Wang, Yan, Zhao, Lue Ping, Dudoit, Sandrine

High-throughput genotyping technologies for SNPs have enabled the recent completion of the International HapMap Project (phase I), which has stimulated much interest in studying genomewide...

Measuring downside risk and severity for global output

Yudong Yao, Yan Wang

This paper attempts to provide a critical measure of downside risk and severity for global output by applying the Value at Risk approach to four country groups in the world as a 'portfolio'. Global...

Kaposi's Sarcoma-Associated Herpesvirus ori-Lyt-Dependent DNA Replication: Dual Role of Replication and Transcription Activator▿

Wang, Yan, Tang, Qiyi, Maul, Gerd G., Yuan, Yan

Lytic replication of Kaposi's sarcoma-associated herpesvirus (KSHV) is essential for viral propagation and pathogenicity. In Kaposi's sarcoma lesions, constant lytic replication plays a role in...

Genome-wide functional analysis of human cell-cycle regulators

Mukherji, Mridul, Bell, Russell, Supekova, Lubica, Wang, Yan, Orth, Anthony P., Batalov, Serge, ...

Human cells have evolved complex signaling networks to coordinate the cell cycle. A detailed understanding of the global regulation of this fundamental process requires comprehensive identification...

A Semiparametric Model for Recapture Experiments

Yan Wang

A two-step procedure based on the conditional likelihood is proposed to estimate the population size of a closed population using a semiparametric model for recapture studies. An asymptotic variance...

Regulation of αA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin

Yang, Ying, Stopka, Tomáš, Golestaneh, Nady, Wang, Yan, Wu, Kongming, Li, Anping, ...

Pax6 and c-Maf regulate multiple stages of mammalian lens development. Here, we identified novel distal control regions (DCRs) of the αA-crystallin gene, a marker of lens fiber cell differentiation...

Fragile X mental retardation protein controls trailer hitch expression and cleavage furrow formation in Drosophila embryos

Monzo, Kate, Papoulas, Ophelia, Cantin, Greg T., Wang, Yan, Yates, John R., Sisson, John C.

During the cleavage stage of animal embryogenesis, cell numbers increase dramatically without growth, and a shift from maternal to zygotic genetic control occurs called the midblastula transition....

Experimental Autoimmune Myocarditis in A/J mice Is an Interleukin-4-Dependent Disease with a Th2 Phenotype

Afanasyeva, Marina, Wang, Yan, Kaya, Ziya, Park, Sung, Zilliox, Michael J., Schofield, Brian H., ...

Myocarditis in humans is often associated with an autoimmune process in which cardiac myosin (CM) is a major autoantigen. Experimental autoimmune myocarditis (EAM) is induced in mice by immunization...

Reduction of Worm Fecundity and Canine Host Blood Loss Mediates Protection against Hookworm Infection Elicited by Vaccination with Recombinant Ac-16▿

Fujiwara, Ricardo T., Zhan, Bin, Mendez, Susana, Loukas, Alex, Bueno, Lilian L., Wang, Yan, ...

Hookworm infection is one of most important parasitic infection of humans, occurring in 740 million people. Here we report the protective vaccination of dogs with Ac-16, an immunodominant surface...

Genomic identification and in vitro reconstitution of a complete biosynthetic pathway for the osmolyte di-myo-inositol-phosphate

Rodionov, Dmitry A., Kurnasov, Oleg V., Stec, Boguslaw, Wang, Yan, Roberts, Mary F., Osterman, Andrei L.

Di-myo-inositol 1,1′-phosphate (DIP) is a major osmoprotecting metabolite in a number of hyperthermophilic species of archaea and bacteria. Although the DIP biosynthesis pathway was previously...

The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription

Zhang, Hua, Sun, Luyang, Liang, Jing, Yu, Wenhua, Zhang, Ying, Wang, Yan, ...

The ubiquitin–proteasome system plays an important role in a variety of cellular functions by means of its proteolytic activity. Interestingly, recent studies have indicated that the proteasome...

Rapid Detection of Hepatitis B Virus Surface Antigen by an Agglutination Assay Mediated by a Bispecific Diabody against Both Human Erythrocytes and Hepatitis B Virus Surface Antigen▿

Chen, Yu-Ping, Qiao, Yuan-Yuan, Zhao, Xiao-Hang, Chen, Hong-Song, Wang, Yan, Wang, Zhuozhi

Bispecific antibodies have immense potential for use in clinical applications. In the present study, a bispecific diabody against human red blood cells (RBCs) and hepatitis B virus surface antigen...

Drug-Induced Epigenetic Changes Produce Drug Tolerance

Wang, Yan, Krishnan, Harish R, Ghezzi, Alfredo, Yin, Jerry C. P, Atkinson, Nigel S

Tolerance to drugs that affect neural activity is mediated, in part, by adaptive mechanisms that attempt to restore normal neural excitability. Changes in the expression of ion channel genes are...

Integration of Estrogen and Wnt Signaling Circuits by the Polycomb Group Protein EZH2 in Breast Cancer Cells▿

Shi, Bin, Liang, Jing, Yang, Xiaohan, Wang, Yan, Zhao, Youna, Wu, Huijian, ...

Essential for embryonic development, the polycomb group protein enhancer of zeste homolog 2 (EZH2) is overexpressed in breast and prostate cancers and is implicated in the growth and aggression of...

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity

Yang, Wu, Guastella, John, Huang, Jin-Cheng, Wang, Yan, Zhang, Li, Xue, Dong, ...

Caspases play a critical role in apoptosis, and are considered to be key targets for the design of cytoprotective drugs. As part of our antiapoptotic drug-discovery effort, we have synthesized and...

Downregulation of Rap1GAP Contributes to Ras Transformation▿

Tsygankova, Oxana M., Prendergast, Gregory V., Puttaswamy, Kanchan, Wang, Yan, Feldman, Michael D., Wang, Hongbin, ...

Although abundant in well-differentiated rat thyroid cells, Rap1GAP expression was extinguished in a subset of human thyroid tumor-derived cell lines. Intriguingly, Rap1GAP was downregulated...

Quantitative Proteomics Identifies Surfactant-Resistant α-Synuclein in Cerebral Cortex of Parkinsonism-Dementia Complex of Guam but Not Alzheimer’s Disease or Progressive Supranuclear Palsy

Yang, Wan, Woltjer, Randall L., Sokal, Izabela, Pan, Catherine, Wang, Yan, Brodey, Mary, ...

Parkinsonism-dementia complex (PDC) remains a significant health burden to the Chamorro population. We tested the hypothesis that quantitative proteomics might provide fresh insight into this...

Identification of surface-exposed components of MOMP of Chlamydia trachomatis serovar F

Wang, Yan, Berg, Eric A., Feng, Xiaogeng, Shen, Li, Smith, Temple, Costello, Catherine E., ...

The identification of surface-exposed components of the major outer membrane protein (MOMP) of Chlamydia is critical for modeling its three-dimensional structure, as well as for understanding the...

Trade remedies and non-market economies : economic implications of the first US countervailing duty case on China

Zhao, Longyue, Wang, Yan

In 2007, the United States Department of Commerce altered a 23-year old policy of not applying the countervailing duty law to non-market economies, and initiated eight countervailing and antidumping...

Multipattern Consensus Regions in Multiple Aligned Protein Sequences and Their Segmentation

Chiu, David K. Y., Wang, Yan

Decomposing a biological sequence into its functional regions is an important prerequisite to understand the molecule. Using the multiple alignments of the sequences, we evaluate a segmentation based...

Ownership structure, corporate governance, and corporate performance : the case of Chinese stock companies

Xiaonian Xu, Yan Wang

The authors investigate whether ownership structure significantly affects the performance of publicly listed firms in China and if so, in what way. With publicly listed stocks, one can quantify the...

Addressing the education puzzle : the distribution of education and economic reform

Lopez, Ramon, Thomas, Vinod, Yan Wang

No country has achieved sustained economic development without substantially investing in human capital. Previous studies have shown the handsome returns to various forms of basic education,...

Implicit pension debt, transition cost, options, and impact of China's pension reform : a computable general equilibrium analysis

Yan Wang, Dianqing Xu, Zhi Wang

The main problems with China's pension system--the pension burdens of state enterprises and the agency of the population--have deepened in recent years. Using a new computable general equilibrium...

China's growth and poverty reduction - trends between 1990 and 1999

Shaohua Chen, Yan Wang

The authors investigate recent rends in poverty, and inequality in China, decomposing data on poverty reduction to see who has benefited most from China's economic growth. They find that, by several...

Measuring economic downside risk and severity - Growth at Risk

Yan Wang, Yudong Yao

Output collapses, and crises are a fact of life. Severe economic downturns occur periodically, and have grave consequences on the poor. The authors propose a new measurement for economic downside...

Foreign bank entry, performance of domestic banks, and sequence of financial liberalization

Bayraktar, Nihal, Yan Wang

The openness or internationalization of financial services is a complex issue because it is closely related to structural reforms in the domestic financial sector with some perceived implications for...

Banking sector openness and economic growth

Bayraktar, Nihal, Wang, Yan

Banking sector openness may directly affect growth by improving the access to financial services and indirectly by improving the efficiency of financial intermediaries, both of which reduce the cost...

How macroeconomic policies affect project performance in the social sectors

Kaufman, Daniel, Yan Wang

The main objective of this study is to explore the realationship between a country's overall economic policy environment and the performance of investment projects in the social sectors. The authors...

Sequential Procedure For Fixed Accuracy Estimation of the Population Size in Recapture Sampling

Xiangzhong Fang, Yong Zhou, Yan Wang

A sequential procedure is constructed to provide a fixed-accuracy estimator for the number of faults in a system. This paper focuses on the case when faults are homogeneous. However, the method can...

Engineered chromosome regions with altered sequence composition demonstrate hierarchical large-scale folding within metaphase chromosomes

Strukov, Yuri G., Wang, Yan, Belmont, Andrew S.

Mitotic chromosome structure and DNA sequence requirements for normal chromosomal condensation remain unknown. We engineered labeled chromosome regions with altered scaffold-associated region (SAR)...

Market returns, transfers and demand for schooling in Malaysia, 1976-89

Kathryn Anderson, Elizabeth King, Yan Wang

If parents expect higher market returns to schooling or additional transfers from their children, they invest more in their children's schooling. Results from models of schooling demand using data...

Inequality and Poverty in China: Institutional Change and Public Policy, 1978 to 1988.

Ahmad, Ehtisham, Wang, Yan

There is considerable uncertainty and debate about changes in poverty and living standards that are likely to occur in an economy in transition from centrally planned allocations to a more...

Quantification and Visualization of LD Patterns and Identification of Haplotype Blocks

Yan Wang, Sandrine Dudoit

Classical measures of linkage disequilibrium (LD) between two loci, based only on the joint distribution of alleles at these loci, present noisy patterns. In this paper, we propose a new...

Kaposi's Sarcoma-Associated Herpesvirus ori-Lyt-Dependent DNA Replication: Involvement of Host Cellular Factors▿

Wang, Yan, Li, Hong, Tang, Qiyi, Maul, Gerd G., Yuan, Yan

Herpesvirus lytic DNA replication requires both the cis-acting element, the origin, and trans-acting factors, including virally encoded origin-binding protein, DNA replication enzymes, and auxiliary...

Effects of different types of palatal lateral excisions on growth and development of maxilla and dental arch

Wu, Jun, Zheng, Qian, Shi, Bing, Meng, Tian, Wang, Yan, Li, Sheng, ...

Objective: This study aimed to explore the effects of different types of palatal lateral excisions on the growth and development of the maxilla and dental arch, and to investigate the underlying...

A NEW METHOD TO PREPARE THE NOVEL ANATASE TiO2

GUANJUN CUI, ZHANXIA XU, YAN WANG, MIN ZHANG, JIANJUN YANG

In this paper, a kind of novel anatase TiO2 nanoparticle with single-electron-trapped oxygen vacancies was prepared by hydrothermal treated nanotube titanic acid. The morphology, structure, and...

Cyclin T1-Dependent Genes in Activated CD4+ T and Macrophage Cell Lines Appear Enriched in HIV-1 Co-Factors

Yu, Wendong, Ramakrishnan, Rajesh, Wang, Yan, Chiang, Karen, Sung, Tzu-Ling, Rice, Andrew P.

HIV-1 is dependent upon cellular co-factors to mediate its replication cycle in CD4+ T cells and macrophages, the two major cell types infected by the virus in vivo. One critical co-factor is Cyclin...

Genetic characterization of Measles Viruses in China, 2004

Zhang, Yan, Ji, Yixin, Jiang, Xiaohong, Xu, Songtao, Zhu, Zhen, Zheng, Lei, ...

Genetic characterization of wild-type measles virus was studied using nucleotide sequencing of the C-terminal region of the N protein gene and phylogenetic analysis on 59 isolates from 16 provinces...

Circulating blood cells function as a surveillance system for damaged tissue in Drosophila larvae

Babcock, Daniel T., Brock, Amanda R., Fish, Greg S., Wang, Yan, Perrin, Laurent, Krasnow, Mark A., ...

Insects have an open circulatory system in which the heart pumps blood (hemolymph) into the body cavity, where it directly bathes the internal organs and epidermis. The blood contains free and...

China's Integration with the World: Development as a Process of Learning and Industrial Upgrading

Yifu, Justin, Wang, Yan

The process of development is full of uncertainties, especially if it is a process of transition from a planned economy to a market oriented one. Because of uncertainties and country specificity,...

Transgenic Mice Overexpressing Peroxiredoxin 6 Show Increased Resistance to Lung Injury in Hyperoxia

Wang, Yan, Phelan, Shelley A., Manevich, Yefim, Feinstein, Sheldon I., Fisher, Aron B.

Peroxiredoxin 6 (Prdx6) is a novel peroxidase enzyme that is expressed at a high level in the lung. We tested the hypothesis that transgenic (Tg) mice overexpressing Prdx6 would exhibit increased...

A single posterior approach for multilevel modified vertebral column resection in adults with severe rigid congenital kyphoscoliosis: a retrospective study of 13 cases

Wang, Yan, Zhang, Yonggang, Zhang, Xuesong, Huang, Peng, Xiao, Songhua, Wang, Zheng, ...

We report a multilevel modified vertebral column resection (MVCR) through a single posterior approach and clinical outcomes for treatment of severe congenital rigid kyphoscoliosis in adults....

Ultrastructure and melatonin 1a receptor distribution in the ovaries of African ostrich chicks

Wang, Yan, Peng, Ke-Mei, Li, Jian-Li, Song, Hui, Li, Sheng-He, Wei, Lan, ...

Healthy 90-day-old ostrich chicks were used in the present study. The ultrastructure and melatonin 1a receptor (MT1) distribution in the ovaries of ostrich chicks was observed by transmission...

Efficient reproduction of cynomolgus monkey using pronuclear embryo transfer technique

Sun, Qiang, Dong, Juan, Yang, Wenting, Jin, Yujuan, Yang, Mingying, Wang, Yan, ...

One of the technical bottlenecks in producing nonhuman primate models is that current assisted reproductive techniques, such as in vitro culture and frozen conservation of multicell-stage embryos,...

Role of color Doppler flow imaging in applicable anatomy of spleen vessels

Xu, Wei-Li, Li, Suo-Lin, Wang, Yan, Li, Meng, Niu, Ai-Guo

AIM: To explore the role of color Doppler flow imaging (CDFI) in visualization of spleen vessels and to define its value for spleen micro-invasive operation.

Direct Quantification of Fusion Rate Reveals a Distal Role for AS160 in Insulin-stimulated Fusion of GLUT4 Storage Vesicles*S⃞

Jiang, Li, Fan, Junmei, Bai, Li, Wang, Yan, Chen, Yu, Yang, Lu, ...

Insulin-stimulated GLUT4 translocation to the plasma membrane constitutes a key process for blood glucose control. However, convenient and robust assays to monitor this dynamic process in real time...

Identification of a differentially expressed gene, ACL, between Meishan × Large White and Large White × Meishan F1 hybrids and their parents

Ren, Zhu-Qing, Wang, Yan, Xu, Yong-Jie, Wang, Lin-Jie, Lei, Ming-Gang, Zuo, Bo, ...

ATP-citrate lyase (ACL), one of the lipogenic enzymes, catalyses the formation of acetyl-coenzyme A (CoA) involved in the synthesis of fatty acid and cholesterol. In pig, very little is known about...

A latent variable regression model for capture-recapture data

Thandrayen, Joanne, Wang, Yan

Capture-recapture methods are used to estimate the prevalence of diseases in the field of epidemiology. The information used for estimation purposes are available from multiple lists, whereby giving...

Characterization of Proteins Associated with Polyglutamine Aggregates: A Novel Approach Towards Isolation of Aggregates from Protein Conformation Disorders

Wang, Yan, Meriin, Anatoli B, Costello, Catherine E, Sherman, Michael Y

The common feature of many neurodegenerative diseases is emergence of protein aggregates. Identifying their composition can provide valuable insights into the cellular mechanisms of protein...

A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates

Chan, Joyce C. Y., Piper, Derek E., Cao, Qiong, Liu, Dongming, King, Chadwick, Wang, Wei, ...

Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates serum LDL cholesterol (LDL-C) by interacting with the LDL receptor (LDLR) and is an attractive therapeutic target for LDL-C lowering....

The Subcellular Localization of TRPP2 Modulates Its Function

Fu, Xiao, Wang, Yan, Schetle, Nelli, Gao, Hongyu, Pütz, Michael, Von Gersdorff, Gero, ...

TRPP2, also known as polycystin-2, is a calcium permeable nonselective cation channel that is mutated in autosomal dominant polycystic kidney disease but has also been implicated in the regulation of...

VisANT 3.5: multi-scale network visualization, analysis and inference based on the gene ontology

Hu, Zhenjun, Hung, Jui-Hung, Wang, Yan, Chang, Yi-Chien, Huang, Chia-Ling, Huyck, Matt, ...

Despite its wide usage in biological databases and applications, the role of the gene ontology (GO) in network analysis is usually limited to functional annotation of genes or gene sets with...

Construction and expression of eukaryotic plasmids containing lamivudine-resistant or wild-type strains of Hepatitis B Virus genotype C

Xu, Wei-Zhen, Fang, Yong, Li, Di, Wang, Yan, Shang, Qing-Long, Li, Gui-Qiu, ...

AIM: To construct eukaryotic expression plasmids of full-length Hepatitis B Virus (HBV) genotype C genome, which contain lamivudine-resistant mutants (YIDD, YVDD) or wild-type strain (YMDD), and to...

Phosphatidylinositol 3-kinase/Akt pathway regulates hepatic stellate cell apoptosis

Wang, Yan, Jiang, Xiao-Yu, Liu, Li, Jiang, Hui-Qing

AIM: To investigate the role of phosphatidylinositol 3-kinase (PI 3-K)/Akt signaling pathway in the balance of HSC activation and apoptosis in rat hepatic stellate cells (HSC).

Baseline predictors of virological response for chronic hepatitis B patients

Wu, Xue-Jie, Wang, Yan, Chen, Ji, Wang, Gui-Qiang

AIM: To determine which baseline factors of chronic hepatitis B patients are predictive of virological response to Peginterferon α-2b therapy.

China's pattern of trade and growth after WTO accession: Lessons for other developing countries

Longyue Zhao, Yan Wang

Purpose – World Trade Organization (WTO) accession marked a new beginning for China's economic, legal and institutional reforms and rapid integration with the rest of the world. The purpose of this...

Differences in conformational dynamics of [Pt3(HPTAB)]6+–DNA adducts with various cross-linking modes

Zhu, Yanyan, Wang, Yan, Chen, Guangju

We present here molecular dynamics simulations and DNA conformational dynamics for a series of trinuclear platinum [Pt3(HPTAB)]6+-DNA adducts [HPTAB = N,N,N′,N′,N′′,N′′-hexakis...

Improving rhizome yield and quality of Paris polyphylla through gibberellic acid-induced retardation of senescence of aerial parts

Yu, Kun, Wang, Yan, Wei, Jianrong, Ma, Qing, Yu, Dan, Li, Jiaru

Senescence in perennials has not been extensively studied compared to that in annual plants, and the effects of delaying senescence on plant biomass and metabolic features in herbaceous perennials...