Weighted-Set Graph Colorings (2009)
We study a weighted-set graph coloring problem in which one assigns $q$ colors to the vertices of a graph such that adjacent vertices have different colors, with a vertex weighting $w$ that either...
A Revisit of the Masuda Flare (2009)
Liu, Rui, Xu, Yan, Wang, Haimin
We revisit the flare on 1992 January 13, which is now universally termed the "Masuda flare". The revisit is motivated not only by its supposed uniqueness despite accumulating observations of hard...
Strategic Disclosure and Stock Returns: Theory and Evidence from US Cross-Listing (2009)
Goto, Shingo, Watanabe, Masahiro, Xu, Yan
When a firm exercises discretion to disclose or withhold information (strategic disclosure), risk-averse investors command higher expected returns when expected cash flows decrease, producing a...
Jin, Guangfu, Xu, Lin, Shu, Yongqian, Tian, Tian, Liang, Jie, Xu, Yan, ...
Chromosome 5p15.33, containing TERT and CLPTM1L genes, was recently identified as one of the susceptible regions for lung cancer in Caucasian populations. We hypothesized that single-nucleotide...
Maryam Mirzaei, Yan Xu, Cynthia B. Elias, Satya Prakash
Human interleukin-7 (hIL-7) is a cytokine secreted by the stromal cells of the red marrow. It is important for proliferation during certain stages of B-cell maturation and for T and NK cell survival,...
Molecular basis of human telomere DNA/RNA structure and its potential application (2009)
Xu, Yan, Suzuki, Yuta, Kaminaga, Kuniyuki, Komiyama, Makoto
Telomeric repeat-containing RNA is a non-coding RNA molecule newly found in mammalian cells. However, structure and function of the telomeric RNA in chromosome ends have not yet been elucidated....
Human telomeric RNA r(UAGGGU) sequence forms parallel tetraplex structure with U-quartet (2009)
Kimura, Takashi, Xu, Yan, Komiyama, Makoto
Recent studies showed that telomere DNAs are transcribed into telomeric-repeat-containing RNAs in mammalian cells and these RNAs are associated with the chromosome ends. Therefore, they may be key...
A spline interpretation of Eulerian numbers (2008)
Wang, Renhong, Xu, Yan, Xu, Zhiqiang
In this paper, we explore the interrelationship between Eulerian numbers and B splines. Specifically, using B splines, we give the explicit formulas of the refined Eulerian numbers, and descents...
Exploring User Experience in “Blended Reality”: Moving Interactions Out of the Screen (2008)
David F. Huynh, Yan Xu, Shuo Wang
Video game players often learn to map their physical actions (e.g., pressing buttons) onto their on-screen avatars ’ actions (e.g., wielding swords) in order to play. We explored the experience...
The Origin and Evolution of \civ Baldwin Effect in QSOs from the Sloan Digital Sky Survey (2008)
Xu, Yan, Bian, Wei-Hao, Yuan, Qi-Rong, Huang, Ke-Liang
Using a large sample of 26623 quasars with redshifts in the range $1.5 \le z\le 5.1$ with \civ $\lambda$1549 \AA emission line in Fifth Data Release of the Sloan Digital Sky Survey (SDSS), we...
Bian, Wei-Hao., Chen, Yan-Mei., Hu, Chen., Huang, Kai., Xu, Yan.
We investigate the $\mbh- \sigma_*$ relation for radio-loud quasars with redshift $z
TIWO: Television in Words. (2008)
This report describes the transformation of feature films into hypervideo by representing their story structures using plot unties. Plot units represent cause-effect relationships between characters...
Bis(1-adamantylammonium) hexafluoridogermanate (2008)
The title compound, (C10H18N)2[GeF6], was obtained hydrothermally from an aqueous solution of GeO2, H3BO3, NiCl2, adamantylammonium chloride, butanol and hydrofluoric acid. The structure consists of...
Maryam Mirzaei, Yan Xu, Cynthia B. Elias, Satya Prakash
Human interleukin-7 (hIL-7) is a cytokine secreted by the stromal cells of the red marrow. It is important for proliferation during certain stages of B-cell maturation and for T and NK cell survival,...
Norcyperone, a Novel Skeleton Norsesquiterpene from Cyperus rotundus L. (2008)
Yan Xu, Hong-Wu Zhang, Chang-Yuan Yu, Yang Lu, Ying Chang, Zhong-Mei Zou
A novel norsesquiterpene, named norcyperone (1), and three known compounds: (-)-clovane-2,9-diol (2), rosenonolactone (3), and 5a,8a-epidioxy-(20S,22E,24R)-ergosta-6,22-dien-3β-ol (4) were...
Natascha Pogori, Ahmad Cheikhyoussef, Yan Xu, Dong Wang
The aim of the study was to investigate the extracellular lipase production by the fungus, Rhizopus chinensis CCTCC M201021. The biochemical characteristics of this lipase were also identified. The...
Zhang, Rongzhen, Zhu, Guangyu, Zhang, Wenchi, Cao, Sheng, Ou, Xianjin, Li, Xuemei, ...
A novel short-chain (S)-1-phenyl-1,2-ethanediol dehydrogenase (SCR) from Candida parapsilosis exhibits coenzyme specificity for NADPH over NADH. It catalyzes an anti-Prelog type reaction to reduce...
Human telomere RNA and DNA form an intermolecular G-quadruplex (2008)
Xu, Yan, Kimura, Takashi, Komiyama, Makoto
For a long time, telomeres have been considered to be transcriptionally silent. Recently, Azzalin et al. demonstrated that telomeres are transcribed into telomeric repeat-containing RNA (TERRA) in...
Human Telomeric RNA in G-quadruplex Structure (2008)
Xu, Yan, Kaminaga, Kuniyuki, Komiyama, Makoto
Very recently, a breaking finding from two groups demonstrated that telomere DNA is transcribed into telomeric repeat-containing RNA in mammalian cells. Telomeric RNA, a newly appeared player in...
CityU Call Number: HQ755.85 .X83 2008
Xu, Yan, Ikegami, Machiko, Wang, Yanhua, Matsuzaki, Yohei, Whitsett, Jeffrey A
Abstract Background The signal transducer and activator of transcription 3 (STAT3) mediates gene expression in response to numerous growth factors and cytokines, playing an important role in many...
Singh, Lisam Shanjukumar, Berk, Michael, Oates, Rhonda, Zhao, Zhenwen, Tan, Haiyan, Jiang, Ying, ...
Background Metastasis is a process by which tumors spread from primary organs to other sites in the body and is the major cause of death for cancer patients. The ovarian cancer G protein–coupled...
Zhang, Zhongjian, Lee, Yi-Ching, Kim, Sung-Jo, Choi, Moonsuk S., Tsai, Pei-Chih, Saha, Arjun, ...
In the majority of neurodegenerative storage disorders, neuronal death in the brain is followed by infiltration of phagocytic cells (e.g. activated microglia, astroglia and macrophages) for the...
Florin M. Selaru, Suna Wang, Jing Yin, Karsten Schulmann, Yan Xu, Yuriko Mori, ...
Background and Aims: Because of the extremely low neoplastic progression rate in Barrett’s esophagus, it is difficult to diagnose patients with concomitant adenocarcinoma early in their disease...
Forthcoming in The Review of Financial Studies (2007)
Shingo Goto, Masahiro Watanabe, Yan Xu, John Griffin, Gustavo Grullon, Andrew Karolyi, ...
Matthew Spiegel (the editor) and anonymous referees for constructive suggestions. All errors are our own. A technical appendix is available on the journal’s and the authors ’ web pages.
This report celebrates the accomplishments of the Microsoft Phoenix Academic Program. Over the last four years, we’ve been fortunate to have the opportunity to work with outstanding professors and...
Patterns of mobilization of social capital of laid-off workers in China (2007)
Thesis (M.Phil.)--Hong Kong University of Science and Technology, 2007
Sequence-specific cleavage of human telomere DNA by G-quadruplex formation (2007)
Xu, Yan, Hirohata, Youhei, Komiyama, Makoto
In the current study, we reported that oligonucleotide with EDTA-Fe at 5′ end causes a sequence specific break in human telomeric DNA strand by G-quadruplex formation.
T-loop formation by human telomeric G-quadruplex (2007)
Xu, Yan, Sato, Hiroyuki, Shinohara, Ken-ichi, Komiyama, Makoto, Sugiyama, Hiroshi
T-loops were a proposed telomere structure and have been speculated to protect telomeres and regulate telomerase. In the current study, we examined the structural and thermodynamic properties of the...
The structural studies of human telomeric DNA using AFM (2007)
Recently, we reported a unique topology of the mixed parallel/antiparallel structure in K+ solution. Taking into account the length of the 3'-terminal single-stranded human telomeric DNA (100-200...
Zhang, Zhongjian, Lee, Yi-Ching, Kim, Sung-Jo, Choi, Moonsuk S., Tsai, Pei-Chih, Saha, Arjun, ...
In the majority of neurodegenerative storage disorders, neuronal death in the brain is followed by infiltration of phagocytic cells (eg. activated microglia, astroglia and macrophages) for the...
The recognition of higher-order G-quadruplex by chiral cyclic-helicene molecules (2006)
Xu, Yan, Yamazaki, Shinya, Osuga, Hideji, Sugiyama, Hiroshi
The G-quadruplex structures represent a new class of molecular targets for DNA-interactive compounds that might be useful for targeting telomeres. Here we describe a study on the structure-based...
Matsugami, Akimasa, Tsuchibayashi, Hiroaki, Xu, Yan, Noguchi, Yuuki, Sugiyama, Hiroshi, Katahira, Masato
The structure of human telomeric DNA has been controversial: the solution structure in the presence of Na+ has been reported to be antiparallel basket-type quadruplex by NMR, while the crystal...
The cumate gene-switch: a system for regulated expression in mammalian cells (2006)
Mullick, Alaka, Xu, Yan, Warren, René, Koutroumanis, Maria, Guilbault, Claire, Broussau, Sophie, ...
Abstract Background A number of expression systems have been developed where transgene expression can be regulated. They all have specific characteristics making them more suitable for certain...
Sweeping from the superfluid to Mott phase in the Bose-Hubbard model (2006)
Schützhold, Ralf, Uhlmann, Michael, Xu, Yan, Fischer, Uwe R.
We study the sweep through the quantum phase transition from the superfluid to the Mott state for the Bose-Hubbard model with a time-dependent tunneling rate $J(t)$. In the experimentally relevant...
Xu, Yan, Ishida, Hiroyuki, Reisen, Daniel, Hanson, Maureen R
Abstract Background Gene expression in Petunia inflata petals undergoes major changes following compatible pollination. Severe flower wilting occurs reproducibly within 36 hours, providing an...
Mode of access: World Wide Web.
The cumate gene-switch: a system for regulated expression in mammalian cells (2006)
Mullick, Alaka, Xu, Yan, Warren, René, Koutroumanis, Maria, Guilbault, Claire, Broussau, Sophie, ...
Affiliation: Sophie Broussau, Amelie Pilotte & Bernard Massie : Départment de microbiologie et immunologie, Faculté de médecine, Université de Montréal
Mode of access: World Wide Web.
CityU Call Number: QH545.O72 X8 2006
Although the definitions of active power and nonactive power in a three-phase sinusoidal power system have been accepted as a standard, it has been an issue on how to define instantaneous nonactive...
A generalized instantaneous nonactive power theory for parallel nonactive power compensation (2006)
Thesis (Ph. D.) -- University of Tennessee, Knoxville, 2006.
Zhang, Zhongjian, Lee, Yi-Ching, Kim, Sung-Jo, Choi, Moonsuk S., Tsai, Pei-Chih, Xu, Yan, ...
Numerous proteins undergo modification by palmitic acid (S-acylation) for their biological functions including signal transduction, vesicular transport and maintenance of cellular architecture....
The formation of G-quadruplex and i-motif structures in the 5′ end of the retinoblastoma (Rb) gene was examined using chemical modifications, circular dichroism (CD) and fluorescence spectroscopy....
Lin, Shili, Ding, Jie, Dong, Crystal, Liu, Zhenqiu, Ma, Zhenxu J, Wan, Shuyan, ...
Abstract We compare and contrast the performance of SIMPLE, a Monte Carlo based software, with that of several other methods for linkage and haplotype analyses, focusing on the simulated data from...
Aspects of Cosmic Inflation in Expanding Bose-Einstein Condensates (2005)
Uhlmann, Michael, Xu, Yan, Schützhold, Ralf
Phonons in expanding Bose-Einstein condensates with wavelengths much larger than the healing length behave in the same way as quantum fields within a universe undergoing an accelerated expansion....
Range table from nannofossils in Hole 156-948C (2005)
Xu, Yan, Shipley, Thomas H, Ogawa, Yujiro, Shipboard Scientific Party
Paleontological investigation on nannofossils of Hole 156-948C (2005)
Xu, Yan, Shipley, Thomas H, Ogawa, Yujiro, Shipboard Scientific Party
Mean-field expansion in Bose-Einstein condensates with finite-range interactions (2005)
Schützhold, Ralf, Uhlmann, Michael, Xu, Yan, Fischer, Uwe R.
We present a formal derivation of the mean-field expansion for dilute Bose-Einstein condensates with two-particle interaction potentials which are weak and finite-range, but otherwise arbitrary. The...
Quantum backreaction in dilute Bose-Einstein condensates (2005)
Schützhold, Ralf, Uhlmann, Michael, Xu, Yan, Fischer, Uwe R.
For many physical systems which can be approximated by a classical background field plus small (linearized) quantum fluctuations, a fundamental question concerns the correct description of the...
Picard values and derivatives of meromorphic functions (2005)
Let f be a transcendental meromorphic function and R be a rational function, $R\not\equiv 0$ , and let k be a positive integer. In this paper, we obtain some results concerning the zeros of f(k)−R,...
Navigating stories in films (2005)
This report describes the transformation of feature films into hypervideo by representing their story structures using plot unties. Plot units represent cause-effect relationships between characters'...
Quantum transport through a C48N12 based nanodevice (2005)
(Uncorrected OCR) Abstract of thesis entitled QUANTUM TRANSPORT THROUGH A C48N12 BASED NANODEVICE submitted by Xu Yan for the Degree of Master of Philosophy at The University of Hong Kong in December...
Quantum transport through a C48N12 based nanodevice (2005)
(Uncorrected OCR) Abstract of thesis entitled QUANTUM TRANSPORT THROUGH A C48N12 BASED NANODEVICE submitted by Xu Yan for the Degree of Master of Philosophy at The University of Hong Kong in December...
Quantum transport through a C48N12 based nanodevice (2005)
(Uncorrected OCR) Abstract of thesis entitled QUANTUM TRANSPORT THROUGH A C48N12 BASED NANODEVICE submitted by Xu Yan for the Degree of Master of Philosophy at The University of Hong Kong in December...
Information sharing in work groups : a transactive memory approach / (2005)
Thesis (Ph. D.)--University of Southern California, 2005.
Xu, Yan, Cook, Thomas J., Knipp, Gregory T.
Di-(2-ethylhexyl)-phthalate (DEHP) is a widely used plasticizer and ubiquitous environmental contaminant. The potential health hazards, including teratogenicity, from exposure to DEHP may be related...
The thermal stability of a G-quartet formed by incorporation of 8-methylguanine (m8G) in the DNA sequence at the 5′ terminus of the Rb gene was examined by CD melting experiments. Substitutions of...
Reactivity of 2'-deoxyuridin-1'-yl radical in various DNA structures (2005)
Hasiba, Waka, Xu, Yan, Sugiyama, Hiroshi
DNA C1′ radicals formed by hydrogen atom abstraction from the C1′ position of the sugar backbone lead to the production of 2′-deoxyribonolactone as a DNA damage lesion. Although DNA C1′...
Song, Jian, Xu, Yan, White, Scott, Miller, Kevin W. P., Wolinsky, Murray
Summary: Single nucleotide polymorphisms (SNPs) are the most abundant form of genetic variations in closely related microbial species, strains or isolates. Some SNPs confer selective advantages for...
Xu, Yan, Cook, Thomas J., Knipp, Gregory T.
Di-(2-ethylhexyl)-phthalate (DEHP) is a widely used plasticizer and ubiquitous environmental contaminant. The potential health hazards, including teratogenecity, from exposure to DEHP may be related...
Song, Jian, Xu, Yan, White, Scott, Miller, Kevin W. P., Wolinsky, Murray
Single nucleotide polymorphisms (SNPs) are the most abundant form of genetic variations among closely related microbial species, strains or isolates. Some SNPs confer selective advantages for...
Zhang, Zhongjian, Lee, Yi-Ching, Kim, Sung-Jo, Choi, Moonsuk S., Tsai, Pei-Chih, Xu, Yan, ...
Numerous proteins undergo modification by palmitic acid (s-acylation) for their biological functions including signal transduction, vesicular transport and maintenance of cellular architecture. While...
Andrew Salway, Yan Xu, Andrew Vassiliou
TIWO Project web-site: www.computing.surrey.ac.uk/personal/pg/A.Salway/tiwo/TIWO.htm Contents 1 EXECUTIVE SUMMARY...............................................................................
Watanabe, Takayoshi, Bando, Toshikazu, Xu, Yan, Sugiyama, Hiroshi
A highly sequence-specific photoreaction of 5′-(G/C)AAXUXU-3′ was found by using 450-base pair DNA fragments containing XU under UV-irradiation (X = Br, I). The molecular basis of this...
Analysis of distamycin A binding to UV-damaged DNA (2004)
Inase, Aki, Kodama, Takashi S., Sharif, Jafar, Xu, Yan, Ayame, Hirohito, Sugiyama, Hiroshi, ...
We have found that distamycin A can bind to DNA duplexes containing the (6–4) photoproduct, one of the major UV lesions in DNA, in spite of the changes caused by photoproduct formation in the...
The recognition of Z-DNA by chiral helicene (2004)
Xu, Yan, Sugiyama, Hiroshi, Tanaka, Kazuhiko, Osuga, Hideji
Enantiomeric helicenes of (P)-A and (M)-A were synthesized. The binding of the helicenes to B- and Z-DNA was studied quantitatively by CD, equilibrium dialysis, and fluorescence spectroscopy....
Xiao Song Liu, Yan Xu, Lani Hardy, Vithagna Khammanivong, Weiming Zhao, ...
This work contradicted earlier work concerning the mechanism of "original antigenic sin" as applied to vaccine induced cytotoxic T cells responses, and demonstrated that IL-10 secreted by helper T...
Linking Video and Text via Representations of Narrative (2003)
Salway, Andrew, Graham, Mike, Tomadaki, Eleftheria, Xu, Yan
The ongoing TIWO project is investigating the synthesis of language technologies, like information extraction and corpus-based text analysis, video data modeling and knowledge representation. The aim...
Liquid-liquid extraction of enzymes by affinity aqueous two-phase systems (2003)
Yan Xu, Souza Maria Aparecida, Vitolo Michele, Pessoa Júnior Adalberto
From analytical to commercial scale, aqueous two-phase systems have their application in the purification, characterization and study of biomaterials. In order to improve the selectivity of the...
Fabrication of three-dimensional opal and inverse opal structures for photonic crystals / (2003)
Thesis (M.E.E.)--University of Delaware, 2004.
Liu, Xiao Song, Xu, Yan, Hardy, Lani, Khammanivong, Vithagna, Zhao, Weiming M., Fernando, Germain J. P., ...
Priming to Ag can inhibit subsequent induction of an immune response to a new epitope incorporated into that Ag, a phenomenon referred to as original antigenic sin. In this study, we show that prior...
Synthesis and characterization of nanocrystalline Cu(CuOx)/Al2O3 composite thin films / (2003)
Thesis (M.Phil.)--Chinese University of Hong Kong, 2003.
Liu, Xiao Song, Xu, Yan, Hardy, Lani, Khammanivong, Vithagna, Zhao, Weiming M., Fernando, Germain J. P., ...
Priming to Ag can inhibit subsequent induction of an immune response to a new epitope incorporated into that Ag, a phenomenon referred to as original antigenic sin. In this study, we show that prior...
Andrew Salway, Mike Graham, Eleftheria Tomadaki and Yan Xu, (2003)
Linking Video And, Andrew Salway, Mike Graham, Eleftheria Tomadaki, Yan Xu
The ongoing TIWO project is investigating the synthesis of language technologies, like information extraction and corpus-based text analysis, video data modeling and knowledge representation. The aim...
Towards artificial repair of UV-damaged DNA: studies on drug binding and alkali hydrolysis (2003)
Iwai, Shigenori, Inase, Aki, Jafar, Sharif, Higurashi, Miho, Ohtsuki, Takashi, Xu, Yan, ...
Properties of the DNA containing the (6-4) photoproduct, one of the major UV-induced lesions, were analyzed. Two basic studies towards artificial recognition and repair of this type of damaged DNA...
Photoreactivity of 5-iodouracil-containing telomeric DNA (2003)
The photoreaction of 5-iodouracil-(IU)-containing telomeric oligonucleotides in parallel or antiparallel structures, generated in the presence of K+ or Na+ ions, was investigated. It was...
Towards artificial repair of UV-damaged DNA: studies on drug binding and alkali hydrolysis (2003)
Iwai, Shigenori, Inase, Aki, Jafar, Sharif, Higurashi, Miho, Ohtsuki, Takashi, Xu, Yan, ...
Thesis (doctoral)--Technische Universität, Berlin.
Dale, C. Jane, Liu, Xiao Song Song, De Rose, Robert, Purcell, Damian F. J., Anderson, Jenny, Xu, Yan, ...
Vaccines to efficiently block or limit sexual transmission of both HIV and human papilloma virus (HPV) are urgently needed. Chimeric virus-like-particle (VLP) vaccines consisting of both multimerized...
Dale, C. Jane, Liu, Xiao Song Song, De Rose, Robert, Purcell, Damian F. J., Anderson, Jenny, Xu, Yan, ...
Vaccines to efficiently block or limit sexual transmission of both HIV and human papilloma virus (HPV) are urgently needed. Chimeric virus-like-particle (VLP) vaccines consisting of both multimerized...
Jia, Hong-Bin, Yu, Jie-Hui, Xu, Ji-Qing, Ding, Hong, Jing, Wei-Jie, Liu, Yong-Jiang, ...
Complex [Fe(bzta)2(ox)]n (1) was synthesized from K3[Fe(ox)3]·3H2O and benzotriazole. Single-crystal X-ray diffraction study of complex 1 has established a novel structure containing several kinds...
3G mobile policy : the case of China and Hong Kong SAR (2001)
A case study prepared for International Telecommunication Union.
Different Pathways Mediate Cytochrome c Release After Photodynamic Therapy with Hypericin (2001)
Annelies Vantieghem, Yan Xu, Wim Declercq, Peter Vandenabeele, Geertrui Denecker, Jackie R. Vandenheede, ...
In this study we show that overexpression of Bcl-2 in PC60R1R2 cells reveals a caspase-dependent mechanism of cytochrome c release following photodynamic therapy (PDT) with hypericin. Bcl-2...
Different pathways mediate cytochrome c release after photodynamic therapy with hypericin (2001)
Xu, Yan, Declerck, Wim, Vandenabeele, Peter, Denecker, Geertrui, ...
In this study we show that overexpression of Bcl-2 in PC60R1R2 cells reveals a caspase-dependent mechanism of cytochrome c release following photodynamic therapy (PDT) with hypericin. Bcl-2...
Bioaccumulation and elimination of trace metals in marine copepods /--by Xu Yan. (2001)
Thesis (M.Phil.)--Hong Kong University of Science and Technology, 2001.
A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Master of Science in Chemical Engineering, Dept. of Chemical and...
Thesis (M.S.)--University of Southern California, 2001.
Bioaccumulation and elimination of trace metals in marine copepods (2001)
Thesis (M.Phil.)--Hong Kong University of Science and Technology, 2001
Fixed-mobile interconnection : the case of China and Hong Kong SAR (2000)
A case study prepared for International Telecommunication Union.
Printout.
This dissertation research involves modeling of the mechanism of brittle fracture whereby diffusion of surface-adsorbed impurities along a grain boundary or interface, which is driven by the...
Typescript (photocopy).
Parallelization of the canal subsystem of the Everglades Landscape Model (Florida) (1997)
Environmental simulations are computationally very demanding. South Florida Water Management District has implemented the Everglades Landscape Model (ELM) to simulate the ecosystem in South Florida....
Parallelization of the canal subsystem of the Everglades landscape model / (1997)
Typescript (Photocopy).
Includes bibliographical references (leaves 107-110)
Two level pipelined bit-serial systolic array for RSA cryptography / (1995)
Includes appendices.
Thèse (M.Sc.) -- Université Laval, 1993.
The development of ultra-sensitive electrochemical enzyme immunoassays /--by Yan Xu. (1991)
Includes abstract.
Thesis (Ph. D.)--State University of New York at Stony Brook, 1990.
Thesis (Ph. D.)--The University at Albany, State University of New York, Dept. of Chemistry, 1988.
Thesis (M.S.)--California State University, Fresno.
Programmed Cell Death during Pollination-Induced Petal Senescence in Petunia1
Petal senescence, one type of programmed cell death (PCD) in plants, is a genetically controlled sequence of events comprising its final developmental stage. We characterized the pollination-induced...
Engineering a nicking endonuclease N.AlwI by domain swapping
Xu, Yan, Lunnen, Keith D., Kong, Huimin
Changing enzymatic function through genetic engineering still presents a challenge to molecular biologists. Here we present an example in which changing the oligomerization state of an enzyme changes...
Amara, Rama Rao, Smith, James M., Staprans, Silvija I., Montefiori, David C., Villinger, Francois, Altman, John D., ...
Cellular immune responses against epitopes in conserved Gag and Pol sequences of human immunodeficiency virus type 1 have become popular targets for candidate AIDS vaccines. Recently, we used a...
Amara, Rama Rao, Villinger, Francois, Staprans, Silvija I., Altman, John D., Montefiori, David C., Kozyr, Natalia L., ...
Recently we demonstrated the control of a mucosal challenge with a pathogenic chimera of simian and human immunodeficiency virus (SHIV-89.6P) by priming with a Gag-Pol-Env-expressing DNA and boosting...
Interactions of volatile anesthetics with the central nervous system are characterized by low yet specific binding affinities. Although neurotransmitter-gated ion channels are considered the primary...
Di Mascio, Michele, Dornadula, Geethanjali, Zhang, Hui, Sullivan, Julie, Xu, Yan, Kulkosky, Joseph, ...
Three of five virally suppressed human immunodeficiency virus type I (HIV-1)-infected patients treated with highly active antiretroviral therapy and followed intensively with a supersensitive reverse...
Ebara, Tetsu, Conde, Karin, Kako, Yuko, Liu, Yanzhu, Xu, Yan, Ramakrishnan, Rajasekhar, ...
We used wild-type (WT) mice and mice engineered to express either apoB-100 only (B100 mice) or apoB-48 only (B48 mice) to examine the effects of streptozotocin-induced diabetes (DM) on apoB-100–...
Xu, Yan, Kulkosky, Joseph, Acheampong, Edward, Nunnari, Giuseppe, Sullivan, Julie, Pomerantz, Roger J.
The induction of neuronal cell death in vivo has been recognized as a prominent feature of HIV type I (HIV-1) infection leading to HIV-1-induced encephalopathy. Viral and host cell products, released...
Foxa2 is required for transition to air breathing at birth
Wan, Huajing, Xu, Yan, Ikegami, Machiko, Stahlman, Mildred T., Kaestner, Klaus H., Ang, Siew-Lan, ...
Toward the end of gestation in mammals, the fetal lung undergoes a process of differentiation that is required for transition to air breathing at birth. Respiratory epithelial cells synthesize the...
Wang, Feng-Xiang, Xu, Yan, Sullivan, Julie, Souder, Emily, Argyris, Elias G., Acheampong, Edward A., ...
The persistence of HIV-1 in virally suppressed infected individuals on highly active antiretroviral therapy (HAART) remains a major therapeutic problem. The use of cytokines has been envisioned as an...
Helicase-dependent isothermal DNA amplification
Vincent, Myriam, Xu, Yan, Kong, Huimin
Polymerase chain reaction is the most widely used method for in vitro DNA amplification. However, it requires thermocycling to separate two DNA strands. In vivo, DNA is replicated by DNA polymerases...
Tang, Pei, Mandal, Pravat K, Xu, Yan
Glycine receptors (GlyR) are the primary inhibitory receptors in the spinal cord and belong to a superfamily of ligand-gated ion channels (LGICs) that are extremely sensitive to low-affinity...
Saladino, Alexander C., Xu, Yan, Tang, Pei
A three-dimensional model of the transmembrane domain of a neuronal-type nicotinic acetylcholine receptor (nAChR), (α4)2(β2)3, was constructed from a homology structure of the muscle-type nAChR...
Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb)
The formation of G-quadruplex and i-motif structures in the 5′ end of the retinoblastoma (Rb) gene was examined using chemical modifications, circular dichroism (CD) and fluorescence spectroscopy....
C3d enhancement of neutralizing antibodies to measles hemagglutinin
Green, Thomas D., Newton, Bruce R., Rota, Paul A., Xu, Yan, Robinson, Harriet L., Ross, Ted M.
Measles remains a major cause of worldwide infant mortality despite the use of current live attenuated vaccines. New approaches to measles virus (MV) vaccine development are critical to interrupt the...
Liu, Zhanwu, Xu, Yan, Tang, Pei
It was recently postulated that the effects of general anesthetics on protein global dynamics might underlie a unitary molecular mechanism of general anesthesia. To verify that the specific dynamics...
Upregulation of a tonoplast-localized cytochrome P450 during petal senescence in Petunia inflata
Xu, Yan, Ishida, Hiroyuki, Reisen, Daniel, Hanson, Maureen R
Simultaneous amplification and screening of whole plasmids using the T7 bacteriophage replisome
Xu, Yan, Kim, Hyun-jin, Kays, Ann, Rice, Jared, Kong, Huimin
This study describes a novel helicase-mediated isothermal DNA amplification method that exponentially amplifies circular DNAs. The circular helicase-dependent amplification (cHDA) system is based on...
Anesthetic Interaction with Ketosteroid Isomerase: Insights from Molecular Dynamics Simulations
Yonkunas, Michael J., Xu, Yan, Tang, Pei
The nature and the sites of interactions between anesthetic halothane and homodimeric Δ5-3-ketosteroid isomerase (KSI) are characterized by flexible ligand docking and confirmed by 1H-15N NMR. The...
Calcineurin/Nfat signaling is required for perinatal lung maturation and function
Davé, Vrushank, Childs, Tawanna, Xu, Yan, Ikegami, Machiko, Besnard, Valérie, Maeda, Yutaka, ...
Pulmonary surfactant proteins and lipids are required for lung function after birth. Lung immaturity and resultant surfactant deficiency cause respiratory distress syndrome, a common disorder...
The cumate gene-switch: a system for regulated expression in mammalian cells
Mullick, Alaka, Xu, Yan, Warren, René, Koutroumanis, Maria, Guilbault, Claire, Broussau, Sophie, ...
Programmed Cell Death during Pollination-Induced Petal Senescence in Petunia1
Petal senescence, one type of programmed cell death (PCD) in plants, is a genetically controlled sequence of events comprising its final developmental stage. We characterized the pollination-induced...
Engineering a nicking endonuclease N.AlwI by domain swapping
Xu, Yan, Lunnen, Keith D., Kong, Huimin
Changing enzymatic function through genetic engineering still presents a challenge to molecular biologists. Here we present an example in which changing the oligomerization state of an enzyme changes...
Amara, Rama Rao, Smith, James M., Staprans, Silvija I., Montefiori, David C., Villinger, Francois, Altman, John D., ...
Cellular immune responses against epitopes in conserved Gag and Pol sequences of human immunodeficiency virus type 1 have become popular targets for candidate AIDS vaccines. Recently, we used a...
Amara, Rama Rao, Villinger, Francois, Staprans, Silvija I., Altman, John D., Montefiori, David C., Kozyr, Natalia L., ...
Recently we demonstrated the control of a mucosal challenge with a pathogenic chimera of simian and human immunodeficiency virus (SHIV-89.6P) by priming with a Gag-Pol-Env-expressing DNA and boosting...
Interactions of volatile anesthetics with the central nervous system are characterized by low yet specific binding affinities. Although neurotransmitter-gated ion channels are considered the primary...
Di Mascio, Michele, Dornadula, Geethanjali, Zhang, Hui, Sullivan, Julie, Xu, Yan, Kulkosky, Joseph, ...
Three of five virally suppressed human immunodeficiency virus type I (HIV-1)-infected patients treated with highly active antiretroviral therapy and followed intensively with a supersensitive reverse...
Ebara, Tetsu, Conde, Karin, Kako, Yuko, Liu, Yanzhu, Xu, Yan, Ramakrishnan, Rajasekhar, ...
We used wild-type (WT) mice and mice engineered to express either apoB-100 only (B100 mice) or apoB-48 only (B48 mice) to examine the effects of streptozotocin-induced diabetes (DM) on apoB-100–...
Xu, Yan, Kulkosky, Joseph, Acheampong, Edward, Nunnari, Giuseppe, Sullivan, Julie, Pomerantz, Roger J.
The induction of neuronal cell death in vivo has been recognized as a prominent feature of HIV type I (HIV-1) infection leading to HIV-1-induced encephalopathy. Viral and host cell products, released...
Foxa2 is required for transition to air breathing at birth
Wan, Huajing, Xu, Yan, Ikegami, Machiko, Stahlman, Mildred T., Kaestner, Klaus H., Ang, Siew-Lan, ...
Toward the end of gestation in mammals, the fetal lung undergoes a process of differentiation that is required for transition to air breathing at birth. Respiratory epithelial cells synthesize the...
Wang, Feng-Xiang, Xu, Yan, Sullivan, Julie, Souder, Emily, Argyris, Elias G., Acheampong, Edward A., ...
The persistence of HIV-1 in virally suppressed infected individuals on highly active antiretroviral therapy (HAART) remains a major therapeutic problem. The use of cytokines has been envisioned as an...
Helicase-dependent isothermal DNA amplification
Vincent, Myriam, Xu, Yan, Kong, Huimin
Polymerase chain reaction is the most widely used method for in vitro DNA amplification. However, it requires thermocycling to separate two DNA strands. In vivo, DNA is replicated by DNA polymerases...
Tang, Pei, Mandal, Pravat K, Xu, Yan
Glycine receptors (GlyR) are the primary inhibitory receptors in the spinal cord and belong to a superfamily of ligand-gated ion channels (LGICs) that are extremely sensitive to low-affinity...
Saladino, Alexander C., Xu, Yan, Tang, Pei
A three-dimensional model of the transmembrane domain of a neuronal-type nicotinic acetylcholine receptor (nAChR), (α4)2(β2)3, was constructed from a homology structure of the muscle-type nAChR...
Liu, Zhanwu, Xu, Yan, Tang, Pei
It was recently postulated that the effects of general anesthetics on protein global dynamics might underlie a unitary molecular mechanism of general anesthesia. To verify that the specific dynamics...
Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb)
The formation of G-quadruplex and i-motif structures in the 5′ end of the retinoblastoma (Rb) gene was examined using chemical modifications, circular dichroism (CD) and fluorescence spectroscopy....
Anesthetic Interaction with Ketosteroid Isomerase: Insights from Molecular Dynamics Simulations
Yonkunas, Michael J., Xu, Yan, Tang, Pei
The nature and the sites of interactions between anesthetic halothane and homodimeric Δ5-3-ketosteroid isomerase (KSI) are characterized by flexible ligand docking and confirmed by 1H-15N NMR. The...
Upregulation of a tonoplast-localized cytochrome P450 during petal senescence in Petunia inflata
Xu, Yan, Ishida, Hiroyuki, Reisen, Daniel, Hanson, Maureen R
Simultaneous amplification and screening of whole plasmids using the T7 bacteriophage replisome
Xu, Yan, Kim, Hyun-jin, Kays, Ann, Rice, Jared, Kong, Huimin
This study describes a novel helicase-mediated isothermal DNA amplification method that exponentially amplifies circular DNAs. The circular helicase-dependent amplification (cHDA) system is based on...
Calcineurin/Nfat signaling is required for perinatal lung maturation and function
Davé, Vrushank, Childs, Tawanna, Xu, Yan, Ikegami, Machiko, Besnard, Valérie, Maeda, Yutaka, ...
Pulmonary surfactant proteins and lipids are required for lung function after birth. Lung immaturity and resultant surfactant deficiency cause respiratory distress syndrome, a common disorder...
The cumate gene-switch: a system for regulated expression in mammalian cells
Mullick, Alaka, Xu, Yan, Warren, René, Koutroumanis, Maria, Guilbault, Claire, Broussau, Sophie, ...
Harvey, Shashikumar R., Sait, Sheila N. J., Xu, Yan, Bailey, Joyce L., Penetrante, Remedios M., Markus, Gabor
The question whether urokinase is expressed in human colon cancer by the cancer cells themselves or by surrounding stromal elements such as fibroblasts, macrophages, and leukocytes, which transfer...
Nie, Yao, Xu, Yan, Mu, Xiao Qing, Wang, Hai Yan, Yang, Ming, Xiao, Rong
An alcohol dehydrogenase from Candida parapsilosis CCTCC M203011 was characterized along with its biochemical activity and structural gene. The amino acid sequence shows similarity to those of the...
Bridges, James P., Xu, Yan, Na, Cheng-Lun, Wong, Hector R., Weaver, Timothy E.
Mutations in the gene encoding SP-C (surfactant protein C; SFTPC) have been linked to interstitial lung disease (ILD) in children and adults. Expression of the index mutation, SP-CΔexon4, in...
Liachenko, Serguei, Tang, Pei, Somogyi, George T, Xu, Yan
Investigation with substances that are similar in structure, but different in anaesthetic properties, may lead to further understanding of the mechanisms of general anaesthesia.We have studied the...
Liachenko, Serguei, Tang, Pei, Somogyi, George T, Xu, Yan
The synaptic concentrations of glutamate and γ-aminobutyric acid (GABA) are modulated by their release and re-uptake. The effects of general anaesthetics on these two processes remain unclear. This...
TDP-43 in Familial and Sporadic Frontotemporal Lobar Degeneration with Ubiquitin Inclusions
Cairns, Nigel J., Neumann, Manuela, Bigio, Eileen H., Holm, Ida E., Troost, Dirk, Hatanpaa, Kimmo J., ...
TAR DNA-binding protein 43 (TDP-43) is a major pathological protein of sporadic and familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions (FTLD-U) with or...
Structure of the First Transmembrane Domain of the Neuronal Acetylcholine Receptor β2 Subunit
Bondarenko, Vasyl, Xu, Yan, Tang, Pei
The recent cryoelectron microscopy structure of the Torpedo nicotinic acetylcholine receptor (nAChR) at 4-Å resolution shows long helices for all transmembrane (TM) domains. This is in disagreement...
Dong, Mei, Bridges, James P., Apsley, Karen, Xu, Yan, Weaver, Timothy E.
Mutations in the SFTPC gene associated with interstitial lung disease in human patients result in misfolding, endoplasmic reticulum (ER) retention, and degradation of the encoded surfactant protein C...
Szarecka, Agnieszka, Xu, Yan, Tang, Pei
The new crystal structures of the product-bound firefly luciferase combined with the previously determined substrate-free structures allow for a detailed analysis of the dynamics basis for the...
Mirzaei, Maryam, Xu, Yan, Elias, Cynthia B., Prakash, Satya
Human interleukin-7 (hIL-7) is a cytokine secreted by the stromal cells of the red marrow. It is important for proliferation during certain stages of B-cell maturation and for T and NK cell survival,...
Fu, Yingmei, Guo, Lishuang, Xu, Yan, Zhang, Wenli, Gu, Jiaao, Xu, Jianfeng, ...
Resistance to ciprofloxacin was detected in 111 (48.1%) isolates of Klebsiella pneumoniae from China. GyrA alterations were identified in the ciprofloxacin-resistant and ciprofloxacin-susceptible...
Capillary Electrophoresis Tutorial
This is a more-theoretical-than-average textbook-like chapter on CE and is from the Chemical Educator. If one wanted to teach a course in instrumental analysis without a textbook, this chapter would...
Igaz, Lionel M., Kwong, Linda K., Xu, Yan, Truax, Adam C., Uryu, Kunihiro, Neumann, Manuela, ...
TAR DNA-binding protein (TDP-43) has been recently described as a major pathological protein in both frontotemporal dementia with ubiquitin-positive inclusions (FTLD-U) and amyotrophic lateral...
NMR Study of General Anesthetic Interaction with nAChR β2 Subunit
Bondarenko, Vasyl, Yushmanov, Victor E., Xu, Yan, Tang, Pei
The molecular basis of anesthetic interaction with membrane proteins has been explored via determination of anesthetic effects on the structure and dynamics of the extended second transmembrane...
STAT3 Regulates ABCA3 Expression and Influences Lamellar Body Formation in Alveolar Type II Cells
Matsuzaki, Yohei, Besnard, Valérie, Clark, Jean C., Xu, Yan, Wert, Susan E., Ikegami, Machiko, ...
ATP-Binding Cassette A3 (ABCA3) is a lamellar body associated lipid transport protein required for normal synthesis and storage of pulmonary surfactant in type II cells in the alveoli. In this study,...
NMR studies of a channel protein without membranes: Structure and dynamics of water-solubilized KcsA
Ma, Dejian, Tillman, Tommy S., Tang, Pei, Meirovitch, Eva, Eckenhoff, Roderic, Carnini, Anna, ...
Structural studies of polytopic membrane proteins are often hampered by the vagaries of these proteins in membrane mimetic environments and by the difficulties in handling them with conventional...
Chen, Ya-Nan, Chen, Hong, Xu, Yan, Zhang, Xue, Luo, Yang
AIM: To investigate the effect of pituitary homeobox 1 (PITX1) expression in cases of human gastric cancer on cancer differentiation and progression, and carcinogenesis.
While a great deal of literature has been published in recent years on the ancillary benefits of greenhouse gas mitigation (e.g., reductions in local air pollution), less attention has been focused...
Li, Hui, Wang, Dongmei, Singh, Lisam Shanjukumar, Berk, Michael, Tan, Haiyan, Zhao, Zhenwen, ...
Ovarian cancer G protein-coupled receptor 1 (OGR1) has been shown to be a proton sensing receptor in vitro. We have shown that OGR1 functions as a tumor metastasis suppressor gene when it is...
Strategic Disclosure and Stock Returns: Theory and Evidence from US Cross-Listing
Shingo Goto, Masahiro Watanabe, Yan Xu
When a firm exercises discretion to disclose or withhold information (strategic disclosure), risk-averse investors command higher expected returns when expected cash flows decrease, producing a...
Ma, Dejian, Brandon, Nicole R., Cui, Tanxing, Bondarenko, Vasyl, Canlas, Christian, Johansson, Jonas S., ...
The four-α-helix bundle mimics the transmembrane domain of the Cys-loop receptor family believed to be the protein target for general anesthetics. Using high resolution NMR, we solved the structure...
Cui, Tanxing, Bondarenko, Vasyl, Ma, Dejian, Canlas, Christian, Brandon, Nicole R., Johansson, Jonas S., ...
As a model of the protein targets for volatile anesthetics, the dimeric four-α-helix bundle, (Aα2-L1M/L38M)2, was designed to contain a long hydrophobic core, enclosed by four amphipathic...
Zhang, Rongzhen, Zhu, Guangyu, Zhang, Wenchi, Cao, Sheng, Ou, Xianjin, Li, Xuemei, ...
A novel short-chain (S)-1-phenyl-1,2-ethanediol dehydrogenase (SCR) from Candida parapsilosis exhibits coenzyme specificity for NADPH over NADH. It catalyzes an anti-Prelog type reaction to reduce...
In Vitro Comparison of the Efficacies of Natamycin and Silver Nitrate against Ocular Fungi▿
Xu, Yan, Pang, Guangren, Gao, Chuanwen, Zhao, Dongqing, Zhou, Lutan, Sun, Shengtao, ...
The in vitro activity of the silver nitrate was assessed in comparison with that of natamycin against 128 corneal Fusarium isolates and 90 corneal Aspergillus isolates. MIC90s of silver nitrate were...
Zhang, Rongzhen, Xu, Yan, Sun, Ying, Zhang, Wenchi, Xiao, Rong
A short-chain carbonyl reductase (SCR) from Candida parapsilosis catalyzes an anti-Prelog reduction of 2-hydroxyacetophenone to (S)-1-phenyl-1,2-ethanediol (PED) and exhibits coenzyme specificity for...
Chen, Gang, Korfhagen, Thomas R., Xu, Yan, Kitzmiller, Joseph, Wert, Susan E., Maeda, Yutaka, ...
Various acute and chronic inflammatory stimuli increase the number and activity of pulmonary mucus-producing goblet cells, and goblet cell hyperplasia and excess mucus production are central to the...