Yan Zhao

Publication List Details

Period

1985 - 2009

Number

121

Co-Authors

Aurora-A down-regulates IkappaBα via Akt activation and interacts with insulin-like growth factor-1 induced phosphatidylinositol 3-kinase pathway for cancer cell survival (2009)

Yao, Jin-e, Yan, Min, Guan, Zhong, Pan, Chao-bin, Xia, Liang-ping, Li, Chuan-xing, ...

Abstract Background The mitotic Aurora-A kinase exerts crucial functions in maintaining mitotic fidelity. As a bona fide oncoprotein, Aurora-A aberrant overexpression leads to oncogenic...

Modification of tobacco plant development by sense and antisense expression of the tomato viroid-induced AGC VIIIa protein kinase PKV suggests involvement in gibberellin signaling (2009)

Hammond, Rosemarie W, Zhao, Yan

Abstract Background The serine-threonine protein kinase gene, designated pkv (protein kinase- viroid induced) was previously found to be transcriptionally activated in tomato plants infected with the...

Full-wave parallel dispersive finite-difference time-domain modeling of three-dimensional electromagnetic cloaking structures (2009)

Zhao, Yan, Hao, Yang

A parallel dispersive finite-difference time-domain (FDTD) method for the modeling of three-dimensional (3-D) electromagnetic cloaking structures is presented in this paper. The permittivity and...

Increased PADI4 expression in blood and tissues of patients with malignant tumors (2009)

Chang, Xiaotian, Han, Jinxiang, Pang, Li, Zhao, Yan, Yang, Yi, Shen, Zhonglin

Abstract Background Peptidylarginine deiminase type 4 (PAD4/PADI4) post-translationally converts peptidylarginine to citrulline. Recent studies suggest that PADI4 represses expression of...

The role of glutamate and its receptors in mesocorticolimbic dopaminergic regions in opioid addiction (2009)

Guo, Yuan, Wang, Hui-Ling, Xiang, Xiao-Hui, Zhao, Yan

Accumulating evidence suggests that glutamate, as one of the most important excitatory neurotransmitters in the brain, plays a key role in drug addiction including opioid addiction. There is...

Expression of PADI4 during rheumatoid arthritis development (2009)

Cuirong Bian, Xiaotian Chang, Yan Zhao, Jinqiu Jia, Yunzhong Zhang

Peptidyl deiminase 4 (PADI4) catalyzes peptidylarginine to citrulline. The gene encoding PADI4 is associated with rheumatoid arthritis (RA) in some populations. The levels of PADI4, anti-CCP, and RF...

Prioritizing risk pathways: a novel association approach to searching for disease pathways fusing SNPs and pathways (2009)

Chen, Lina, Zhang, Liangcai, Zhao, Yan, Xu, Liangde, Shang, Yukui, Wang, Qian, ...

Motivation: Complex diseases are generally thought to be under the influence of one or more mutated risk genes as well as genetic and environmental factors. Many traditional methods have been...

Prevalence of tuberculosis drug resistance in 10 provinces of China (2008)

He, Guang, Zhao, Yan, Jiang, Guang, Liu, Yu, Xia, Hui, Wang, Sheng, ...

Abstract Background The emergence of drug-resistant tuberculosis (TB) hampers TB control. Ten provinces in China performed drug resistance surveys among tuberculosis (TB) patients in 1996–2004 to...

Manipulating the Loss in Electromagnetic Cloaks for Perfect Wave Absorption (2008)

Argyropoulos, Christos, Kallos, Efthymios, Zhao, Yan, Hao, Yang

We examine several ways to manipulate the loss in electromagnetic cloaks, based on transformation electromagnetics. It is found that, by utilizing inherent electric and magnetic losses of...

Subwavelength internal imaging by means of the wire medium (2008)

Zhao, Yan, Belov, Pavel A., Hao, Yang

Evanescent wave amplification is observed, for the first time to our knowledge, inside a half-wavelength-thick wire medium slab used for subwavelength imaging. The wire medium is analyzed using both...

A Radial-Dependent Dispersive Finite-Difference Time-Domain Method for the Evaluation of Electromagnetic Cloaks (2008)

Argyropoulos, Christos, Zhao, Yan, Hao, Yang

A radial-dependent dispersive finite-difference time-domain (FDTD) method is proposed to simulate electromagnetic cloaking devices. The Drude dispersion model is applied to model the electromagnetic...

Enhancement of evanescent waves inside media with extreme optical anisotropy (2008)

Belov, Pavel A., Zhao, Yan, Hao, Yang, Parini, Clive

Significant enhancement of evanescent spatial harmonics inside the slabs of media with extreme optical anisotropy is revealed. This phenomenon results from the pumping of standing waves and has the...

International Journal of Systematic and Evolutionary Microbiology (2005), 55, 2131–2141 DOI 10.1099/ijs.0.63655-0 Correspondence (2008)

Yan Zhao

Phytopathogenic spiroplasmas and phytoplasmas are small, cell wall-less bacteria that cause disease in more than 300 vegetable, ornamental and perennial species, representing over 100 plant families...

A Profit-based Business Model for Evaluating Rule (2008)

Yaohua Chen, Yan Zhao, Yiyu Yao

Abstract. Different types of rules are mined from transaction databases often with the goal of improving sales and services. In this paper, we link the interestingness of rules with the context of...

Coarsening Classification Rules on Basis of Granular Computing (2008)

Yan Zhao

The task of classification, as a well-studied field of machine learning and data mining, has two main purposes: describing the classification rules in the training dataset and predicting the unseen...

On Visualizing Negotiation Communication Networks Abstract (2008)

Yan Zhao, Song Ye, James Ford

SCENS, the Secure Content Exchange Negotiation System, is an ongoing project in the

Proceedings of the Second Indian International Conference on Artificial Intelligence (IICAI’05), 2444-2454, 2005. On Interactive Data Mining (2008)

Yan Zhao, Yiyu Yao

Abstract. While many data mining models concentrate on automation and efficiency, interactive data mining models should focus on adaptive and effective communications between human users and computer...

Full-wave finite-difference time-domain simulation of electromagnetic cloaking structures (2008)

Zhao, Yan, Argyropoulos, Christos, Hao, Yang

This paper proposes a radial dependent dispersive finite-difference time-domain method for the modelling of electromagnetic cloaking structures. The permittivity and permeability of the cloak are...

Interface Design for Tracking Negotiations (2008)

Yan Zhao, Fillia Makedon, James Ford, Song Ye

the Dartmouth Experimental Visualization Laboratory (DEVLAB) that aims to build a web-based platform for sharing sensitive data among different parties. In this paper, we describe the development of...

LEVEL-WISE CONSTRUCTION OF DECISION TREES FOR CLASSIFICATION (2008)

Yan Zhao, Yiyu Yao, Jingtao Yao

A partition-based framework is presented for a formal study of classification problems. An information table is used as a knowledge representation, in which all basic notions are precisely defined by...

Level-wise Construction of Decision Trees for Classification (2008)

Yan Zhao, Yiyu Yao, Jing Tao Yao

A partition-based framework is presented for a formal study of classification problems. An information table is used as a knowledge representation, in which all basic notions are precisely defined by...

Duloxetine versus placebo for the treatment of women with stress predominant urinary incontinence in Taiwan: a double-blind, randomized, placebo-controlled trial (2008)

Lin, Alex, Sun, Mou-Jong, Tai, Hui-Lung, Chuang, Yao, Huang, Shih-Tsung, Wang, Nick, ...

Abstract Background This manuscript compares the efficacy and safety of duloxetine with placebo in Taiwanese women with SUI. Methods Taiwanese women with SUI were were randomly assigned to placebo (n...

Nuclear targeting by fragmentation of the Potato spindle tuber viroid genome (2008)

Abraitiene, Asta, Zhao, Yan, Hammond, Rosemarie

Transient expression of engineered reporter RNAs encoding an intron-containing green fluorescent protein (GFP) from a Potato virus X-based expression vector previously demonstrated the nuclear...

Nano Titanium Oxide Organosol: Synthesis, Characterization, and Application for Electrorheological Fluid (2008)

Zhao, Yan, Wang, Baoxiang, Ding, Changlin, Zhao, Xiaopeng

A liquid–liquid phase transfer method was employed to prepare novel nano titanium oxide/silicone oil organosol. First, titanium oxide nanoparticles were synthesized in aqueous phase and then...

Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells (2008)

Wan, Xiang-Bo, Long, Zi-Jie, Yan, Min, Xu, Jie, Xia, Liang-Ping, Liu, Li, ...

Mitotic serine/threonine kinase Aurora-A (Aur-A) plays a critical role in regulating centrosome segregation and spindle assemble. Aur-A overexpression causes excessive centrosome duplication and...

Comparison of 99mTc-annexin A5 with 18F-FDG for the detection of atherosclerosis in ApoE−/− mice (2007)

Zhao, Yan, Kuge, Yuji, Zhao, Songji, Morita, Koichi, Inubushi, Masayuki, Strauss, H. William, ...

Purpose: 99mTc-annexin A5, a marker of ongoing apoptosis, and 18F-FDG, a marker of the increased metabolism of inflammatory cells, are supposed to be useful in the detection of metabolically active...

Gold nanorods mediate tumor cell death by compromising membrane integrity (2007)

Tong, Ling, Zhao, Yan, Huff, Terry B, Hansen, Matthew N, Wei, Alexander, Cheng, Ji-Xin

Folate-conjugated gold nanorods targeted to tumor cell surfaces produced severe membrane damage upon near-infrared irradiation. Photoinduced injury to the plasma membrane resulted in a rapid increase...

Catalytic Asymmetric Dihydroxylation of Olefins Using a Recoverable and Reusable Ligand (2007)

Qiao Feng Wang, Xiao Li Sun, Sheng Yong Zhang, Xiang Yang Qin, Yan Zhao

A free bis-cinchona alkaloid derivative ligand was prepared by a simple synthetic manipulation. With ligand/olefin mole ratio of 1%, the asymmetric dihydroxylation reactions of six olefins proceeded...

Accurate Modelling of Left-Handed Metamaterials Using Finite-Difference Time-Domain Method with Spatial Averaging at the Boundaries (2007)

Zhao, Yan, Belov, Pavel, Hao, Yang

The accuracy of finite-difference time-domain (FDTD) modelling of left-handed metamaterials (LHMs) is dramatically improved by using an averaging technique along the boundaries of LHM slabs. The...

Vitamin E analogs, a novel group of "Mitocans," as anticancer agents: The importance of being redox-silent (2007)

Neuzil, Jiri, Tomasetti, Marco, Zhao, Yan, Dong, Lan-feng, Birringer, Marc, Wang, Xiufang, ...

The search for a selective and efficient anticancer agent for treating all neoplastic disease has yet to deliver a universally suitable compound(s). The majority of established anticancer drugs...

α-tocopheryl succinate-induced apoptosis in human gastric cancer cells is modulated by ERK1/2 and c-Jun N-terminal kinase in a biphasic manner (2007)

Zhao, Yan, Zhao, Xiujuan, Yang, Baofeng, Neuzil, Jiri, Wu, Kun

Gastric neoplastic disease is one of the most frequent causes of cancer-associated deaths with poor prognosis. Here we studied the effect of the redox-silent analogue α-tocopheryl succinate...

Vitamin E analogs, a novel group of "Mitocans," as anticancer agents: The importance of being redox-silent (2007)

Neuzil, Jiri, Tomasetti, Marco, Zhao, Yan, Dong, Lan-feng, Birringer, Marc, Wang, Xiufang, ...

The search for a selective and efficient anticancer agent for treating all neoplastic disease has yet to deliver a universally suitable compound(s). The majority of established anticancer drugs...

α-tocopheryl succinate-induced apoptosis in human gastric cancer cells is modulated by ERK1/2 and c-Jun N-terminal kinase in a biphasic manner (2007)

Zhao, Yan, Zhao, Xiujuan, Yang, Baofeng, Neuzil, Jiri, Wu, Kun

Gastric neoplastic disease is one of the most frequent causes of cancer-associated deaths with poor prognosis. Here we studied the effect of the redox-silent analogue α-tocopheryl succinate...

Vitamin E analogs, a novel group of "Mitocans," as anticancer agents: The importance of being redox-silent (2007)

Neuzil, Jiri, Tomasetti, Marco, Zhao, Yan, Dong, Lan-feng, Birringer, Marc, Wang, Xiufang, ...

The search for a selective and efficient anticancer agent for treating all neoplastic disease has yet to deliver a universally suitable compound(s). The majority of established anticancer drugs...

α-tocopheryl succinate-induced apoptosis in human gastric cancer cells is modulated by ERK1/2 and c-Jun N-terminal kinase in a biphasic manner (2007)

Zhao, Yan, Zhao, Xiujuan, Yang, Baofeng, Neuzil, Jiri, Wu, Kun

Gastric neoplastic disease is one of the most frequent causes of cancer-associated deaths with poor prognosis. Here we studied the effect of the redox-silent analogue α-tocopheryl succinate...

Experimental study of the sub-wavelength imaging by a wire medium slab (2006)

Belov, Pavel A., Zhao, Yan, Sudhakaran, Sunil, Alomainy, Akram, Hao, Yang

An experimental investigation of sub-wavelength imaging by a wire medium slab is performed. A complex-shaped near field source is used in order to test imaging performance of the device. It is...

Accurate modeling of left-handed media using finite-difference time-domain method and finite-size effects of a left-handed medium slab on the image quality revisited (2006)

Zhao, Yan, Belov, Pavel, Hao, Yang

The letter contains an important message regarding the numerical modeling of left-handed media (LHM) using the finite-difference time-domain (FDTD) method which remains at the moment one of the main...

UWB On-Body Radio Channel Modelling Using Ray Theory and Sub-band FDTD Method (2006)

Zhao, Yan, Alomainy, Akram, Hao, Yang, Parini, Clive

This paper presents the ultra-wideband (UWB) on-body radio channel modelling using a sub-band Finite-Difference Time-Domain (FDTD) method and a model combining the uniform geometrical theory of...

Finite-Difference Time-Domain Study of Guided Modes in Nano-plasmonic Waveguides (2006)

Zhao, Yan, Hao, Yang

A conformal dispersive finite-difference time-domain (FDTD) method is developed for the study of one-dimensional (1-D) plasmonic waveguides formed by an array of periodic infinite-long silver...

Spatially dispersive finite-difference time-domain analysis of sub-wavelength imaging by the wire medium slabs (2006)

Zhao, Yan, Belov, Pavel A., Hao, Yang

In this paper, a spatially dispersive finite-difference time-domain (FDTD) method to model wire media is developed and validated. Sub-wavelength imaging properties of the finite wire medium slabs are...

Modelling of Wave Propagation in Wire Media Using Spatially Dispersive Finite-Difference Time-Domain Method: Numerical Aspects (2006)

Zhao, Yan, Belov, Pavel, Hao, Yang

The finite-difference time-domain (FDTD) method is applied for modelling of wire media as artificial dielectrics. Both frequency dispersion and spatial dispersion effects in wire media are taken into...

Vitamin E analogues as anti-cancer agents: Lessons from studies with α-tocopheryl succinate (2006)

Wang, Xiufang, Dong, Lan-feng, Zhao, Yan, Tomasetti, Marco, Wu, Kun, Neuzil, Jiri

The new millennium has witnessed considerable decrease in a number of previously fatal pathologies, largely due to the advancement in molecular medicine and modern approaches to treatment. In spite...

Vitamin E analogues as anti-cancer agents: Lessons from studies with α-tocopheryl succinate (2006)

Wang, Xiufang, Dong, Lan-feng, Zhao, Yan, Tomasetti, Marco, Wu, Kun, Neuzil, Jiri

The new millennium has witnessed considerable decrease in a number of previously fatal pathologies, largely due to the advancement in molecular medicine and modern approaches to treatment. In spite...

Analyzing Actors and Their Discussion Topics by Semantic Social Network Analysis (2006)

Peter A. Gloor, Yan Zhao

iQuest is a novel software system to improve understanding of organizational phenomena with greater precision, clarity, and granularity than has previously been possible. It permits to gain new...

A model of machine learning based on user preference of features (2006)

Yiyu Yao, Yan Zhao, Jue Wang, Suqing Han

Abstract. A formal model of machine learning by considering user preference of attributes is proposed in this paper. The model seamlessly combines internal information and external information. This...

Y.Y.: User-centered Interactive Data Mining (2006)

Yan Zhao, Yaohua Chen, Yiyu Yao

While many data mining models concentrate on automation and efficiency, interactive data mining models focus on adaptive and effective communications between human users and computer systems. User...

A model of machine learning based on user preference of features (2006)

Yiyu Yao, Yan Zhao, Jue Wang, Suqing Han

Abstract. A formal model of machine learning by considering user preference of attributes is proposed in this paper. The model seamlessly combines internal information and external information. This...

Y.Y.: User-centered Interactive Data Mining (2006)

Yan Zhao, Yaohua Chen, Yiyu Yao

While many data mining models concentrate on automation and efficiency, interactive data mining models focus on adaptive and effective communications between human users and computer systems. User...

Vitamin E analogues as anti-cancer agents: Lessons from studies with α-tocopheryl succinate (2006)

Wang, Xiufang, Dong, Lan-feng, Zhao, Yan, Tomasetti, Marco, Wu, Kun, Neuzil, Jiri

The new millennium has witnessed considerable decrease in a number of previously fatal pathologies, largely due to the advancement in molecular medicine and modern approaches to treatment. In spite...

A MODEL FOR STREP THROAT INFECTION: DYNAMICS OF CONTINGENCY GENE SELECTION IN AN INFECTED HOST (2005)

Zhao, Yan

An ordinary differential equations model for strep throat infection is constructed to compute the bacterial population densities of genotype combinations with binary switches in contingency genes....

A MODEL FOR STREP THROAT INFECTION: DYNAMICS OF CONTINGENCY GENE SELECTION IN AN INFECTED HOST (2005)

Zhao, Yan

An ordinary differential equations model for strep throat infection is constructed to compute the bacterial population densities of genotype combinations with binary switches in contingency genes....

Dithiocarbamate Assembly on Gold (2005)

Zhao, Yan, Perez-Segarra, Waleska, Shi, Qicun, Wei, Alexander

Metal surfaces are functionalized by stable dithiocarbamate ligands when exposed to carbon disulfide and secondary amines. The adsorbed dithiocarbamates are robust under a wide pH range and can...

Visualizing Negotiation Communications in Setting Library Sharing Policies (2005)

Ford, James, Zhao, Yan, Ye, Song, Zhang, Sheng, Makedon, Fillia, Le, Zhengyi, ...

Today’s libraries have evolved to contain a very broad and diverse range of resources, each needing different types of conditions for sharing, depending on their modality (from books to videos and...

Cryptic plasmid pSKU146 from the wall-less plant pathogen Spiroplasma kunkelii encodes an adhesin and components of a type IV translocation-related conjugation system (2005)

Davis, Robert E, Dally, Ellen L, Jomantiene, Rasa, Zhao, Yan, Roe, Bruce, Lin, ShaoPing, ...

A cryptic plasmid of the wall-less plant pathogenic mollicute, Spiroplasma kunkelii CR2-3X, was cloned and its sequence analyzed. The 14,615 bp plasmid, designated pSKU146, has a nucleotide content...

Two modes of microsatellite instability in human cancer: differential connection of defective DNA mismatch repair to dinucleotide repeat instability (2005)

Oda, Shinya, Maehara, Yoshihiko, Ikeda, Yoichi, Oki, Eiji, Egashira, Akinori, Okamura, Yoshikazu, ...

Microsatellite instability (MSI) is associated with defective DNA mismatch repair in various human malignancies. Using a unique fluorescent technique, we have observed two distinct modes of...

Design and Performance Analysis of Quasi-Orthogonal Space-Time Block Codes for Four Antennae (2005)

ZHAO, Yan, HE, Chen

In this letter, a novel general design method of quasi-orthogonal space-time block codes for four antennae is presented. Comparison with the design method proposed by Jafarkhani, this method enlarges...

Entanglement concentration for unknown atomic entangled states via entanglement swapping (2004)

Yang, Ming, Zhao, Yan, Song, Wei, Cao, Zhuo-Liang

An entanglement concentration scheme for unknown atomic entanglement states is proposed via entanglement swapping in cavity QED. Because the interaction used here is a large-detuned one between two...

Peter A. Gloor*, Rob Laubacher (2004)

Mit Pgloor Rjl, Peter A. Gloor, Peter A. Gloor, Peter A. Gloor, Rob Laubacher, ...

This paper describes a visual social browser for exploring the evolution of social networks over time. We consider the exchange of e-mails between actors as an approximation of social ties. Our...

Temporal Visualization and Analysis of Social Networks (2004)

Peter A. Gloor, Peter A. Gloor, Peter A. Gloor, Rob Laubacher, Rob Laubacher, ...

This paper describes a visual social browser for exploring the evolution of social networks over time. We consider the exchange of e-mails between actors as an approximation of social ties. Our...

A three-layered conceptual framework of data mining (2004)

Yiyu Yao, Ning Zhong, Yan Zhao

Summary. The study of foundations of data mining may be viewed as a scientific inquiry into the nature of data mining and the scope of data mining methods. There is not enough attention paid to the...

Sodium tanshinone IIA sulfonate mediates electron transfer reaction in rat heart mitochondria (2003)

Zhou, Guangyin, Jiang, Wen, Zhao, Yan, Ma, Guangén, Xin, Wenjuan, Yin, Junjie, ...

In this paper, an electron transfer reaction mediated by sodium tanshinone IIA sulfonate (STS) was studied in rat heart mitochondria. It was found that STS could stimulate mitochondrial NADH...

Explanation-oriented association mining [microform] / (2003)

Zhao, Yan.

Thesis (M.Sc.) -- University of Regina, 2003.

Data Migration for Ontology Evolution (2003)

Zhuo Zhang, Lei Zhang, Chenxi Lin, Yan Zhao, Yong Yu

Ontology is the conceptual backbone that provides meaning to data on the Semantic Web. However, ontology is not a static resource and may evolve over time. Ontology’s change often leaves the...

SCENS: a System for the Mediated Sharing of Sensitive Data (2003)

Song Ye Fillia, Song Ye, Fillia Makedon, Tilmann Steinberg, Li Shen, James Ford, ...

This paper introduces SCENS, a Secure Content Exchange Negotiation System suitable for the exchange of private digital data that reside in distributed digital repositories. SCENS is an open...

On the design and implementation of a web-based negotiation system (2003)

Fillia Makedon, Song Ye, Yan Zhao

System, which we are building to enable the exchange or sharing of private (sensitive) multimodal digital data that reside in distributed digital repositories. These data may include raw data,...

2003c) “A Security Incident Sharing and Classification System for Building Trust (2003)

Fillia Makedon, Song Ye, Tilmann Steinberg, Yan Zhao, Jamies Ford, Zhan Xiao, ...

Abstract: Trust in cross-media applications is essential to successful collaboration. Cross media service delivery encompasses different types of security incidents and assumes a level of trust on...

Efficacious Data Cube Exploration by Semantic Summarization and Compression (2003)

Laks V. S, Jian Pei, Yan Zhao, Lakshmanan Jian, Pei Yan Zhao

Data cube is the core operator in data warehousing and OLAP. Its efficient computation, maintenance, and utilization for query answering and advanced analysis have been the subjects of numerous...

Visualization of Communication Patterns in Collaborative Innovation Networks: Analysis of some W3C working groups (2003)

Peter A. Gloor, Rob Laubacher, Yan Zhao

Collaborative Innovation Networks (COINs) are groups of self-motivated individuals from various parts of an organization or from multiple organizations, empowered by the Internet, who work together...

Technology Induced Change in Film/Television Distribution (2003)

Jon Chang, Kai-wei Chang, Jason Chu, Yunchong Lee, Yan Zhao

supervised by Prof. Uday S. Karmarkar who also participated in the study, and was part of the Business and Information Technologies (BIT) project being conducted at the Center for Management in the...

Likelihood based procedures for general nonlinear structural equation analysis / (2002)

Zhao, Yan.

Valid Statistical inferences in nonlinear structural equation models are of great interest recently. This dissertation aims at fitting a nonlinear structural equation model consisting of two parts; a...

Soil conservation and crop productivity in Yunnan province, P.R. China (2002)

Milne, E., Fullen, Michael A., Hocking, Trevor J., Mitchell, David J., Wu, Bozhi, Liu, Liguang, ...

In Yunnan province, China, 95% of land is mountainous, which necessitates cultivation of steep slopes. This study considered the effectiveness of two soil conservation measures in relation to crop...

Polycystin-2 expression is increased following experimental ischaemic renal injury (2002)

Zhao, Yan, Haylor, John L., Ong, Albert C. M.

Background. Mutations in PKD2 account for 15% of patients with autosomal dominant polycystic kidney disease. Expression of the PKD2 protein, polycystin‐2, is developmentally...

Nirvana of tradition : the rebirth of courtyard housing in Beijing (2000)

Zhao, Yan

This thesis was digitised for the purposes of Document Delivery. It has been made available on open access by Sydney eScholarship and may only be used for the purposes of research and study. Where...

Preliminary Results from a Parallel MATLAB Compiler (1998)

Michael J. Quinn, Alexey Malishevsky, Nagajagadeswar Seelam, Yan Zhao

We are developing a compiler that translates ordinary MATLAB scripts into code suitable for compilation and execution on parallel computers supporting C and the MPI message-passing library. In this...

Two modes of microsatellite instability in human cancer: differential connection of defective DNA mismatch repair to dinucleotide repeat instability

Oda, Shinya, Maehara, Yoshihiko, Ikeda, Yoichi, Oki, Eiji, Egashira, Akinori, Okamura, Yoshikazu, ...

Microsatellite instability (MSI) is associated with defective DNA mismatch repair in various human malignancies. Using a unique fluorescent technique, we have observed two distinct modes of...

Histone H3 Ser10 Phosphorylation-Independent Function of Snf1 and Reg1 Proteins Rescues a gcn5− Mutant in HIS3 Expression

Liu, Yang, Xu, Xinjing, Singh-Rodriguez, Soumya, Zhao, Yan, Kuo, Min-Hao

Gcn5 protein is a prototypical histone acetyltransferase that controls transcription of multiple yeast genes. To identify molecular functions that act downstream of or in parallel with Gcn5 protein,...

Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim

Zhao, Yan, Tan, Jing, Zhuang, Li, Jiang, Xia, Liu, Edison T., Yu, Qiang

Inhibitors of histone deacetylases (HDACIs) are a new generation of anticancer agents that selectively kill tumor cells. However, the molecular basis for their tumor selectivity is not well...

Two modes of microsatellite instability in human cancer: differential connection of defective DNA mismatch repair to dinucleotide repeat instability

Oda, Shinya, Maehara, Yoshihiko, Ikeda, Yoichi, Oki, Eiji, Egashira, Akinori, Okamura, Yoshikazu, ...

Microsatellite instability (MSI) is associated with defective DNA mismatch repair in various human malignancies. Using a unique fluorescent technique, we have observed two distinct modes of...

Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim

Zhao, Yan, Tan, Jing, Zhuang, Li, Jiang, Xia, Liu, Edison T., Yu, Qiang

Inhibitors of histone deacetylases (HDACIs) are a new generation of anticancer agents that selectively kill tumor cells. However, the molecular basis for their tumor selectivity is not well...

Histone H3 Ser10 Phosphorylation-Independent Function of Snf1 and Reg1 Proteins Rescues a gcn5− Mutant in HIS3 Expression

Liu, Yang, Xu, Xinjing, Singh-Rodriguez, Soumya, Zhao, Yan, Kuo, Min-Hao

Gcn5 protein is a prototypical histone acetyltransferase that controls transcription of multiple yeast genes. To identify molecular functions that act downstream of or in parallel with Gcn5 protein,...

A Novel Role for PECAM-1 (CD31) in Regulating Haematopoietic Progenitor Cell Compartmentalization between the Peripheral Blood and Bone Marrow

Ross, Ewan A., Freeman, Sylvie, Zhao, Yan, Dhanjal, Tarvinder S., Ross, Emma J., Lax, Sian, ...

Although the expression of PECAM-1 (CD31) on vascular and haematopoietic cells within the bone marrow microenvironment has been recognized for some time, its physiological role within this niche...

Pivotal contributions of megakaryocytes to the biology of idiopathic myelofibrosis

Ciurea, Stefan O., Merchant, Delwin, Mahmud, Nadim, Ishii, Takefumi, Zhao, Yan, Hu, Wenyang, ...

In order to investigate the biologic processes underlying and resulting from the megakaryocytic hyperplasia that characterizes idiopathic myelofibrosis (IMF), peripheral blood CD34+ cells isolated...

Cutaneous Infrared Thermometry for Detecting Febrile Patients

Hausfater, Pierre, Zhao, Yan, Defrenne, Stéphanie, Bonnet, Pascale, Riou, Bruno

We assessed the accuracy of cutaneous infrared thermometry, which measures temperature on the forehead, for detecting patients with fever in patients admitted to an emergency department. Although...

PKCα regulates platelet granule secretion and thrombus formation in mice

Konopatskaya, Olga, Gilio, Karen, Harper, Matthew T., Zhao, Yan, Karim, Zubair A., ...

Platelets are central players in atherothrombosis development in coronary artery disease. The PKC family provides important intracellular mechanisms for regulating platelet activity, and platelets...

Ancient, recurrent phage attacks and recombination shaped dynamic sequence-variable mosaics at the root of phytoplasma genome evolution

Wei, Wei, Davis, Robert E., Jomantiene, Rasa, Zhao, Yan

Mobile genetic elements have impacted biological evolution across all studied organisms, but evidence for a role in evolutionary emergence of an entire phylogenetic clade has not been forthcoming. We...

Discovery and Characterization of Novel Vascular and Hematopoietic Genes Downstream of Etsrp in Zebrafish

Gomez, Gustavo A., Veldman, Matthew B., Zhao, Yan, Burgess, Shawn, Lin, Shuo

The transcription factor Etsrp is required for vasculogenesis and primitive myelopoiesis in zebrafish. When ectopically expressed, etsrp is sufficient to induce the expression of many vascular and...

Interplay among Etsrp/ER71, Scl, and Alk8 signaling controls endothelial and myeloid cell formation

Sumanas, Saulius, Gomez, Gustavo, Zhao, Yan, Park, Changwon, Choi, Kyunghee, Lin, Shuo

Vascular endothelial and myeloid cells have been proposed to originate from a common precursor cell, the hemangioblast. The mechanism of endothelial and myeloid cell specification and differentiation...

Checkpoint with forkhead-associated and ring finger promoter hypermethylation correlates with microsatellite instability in gastric cancer

Oki, Eiji, Zhao, Yan, Yoshida, Rintaro, Masuda, Takanobu, Ando, Koji, Sugiyama, Masahiiko, ...

AIM: To examine the methylation status of the promoter region of the checkpoint with forkhead-associated and ring finger (CHFR) and microsatellite mutator status in 59 primary gastric cancers.

Genomic Analyses of the Microsporidian Nosema ceranae, an Emergent Pathogen of Honey Bees

Cornman, R. Scott, Chen, Yan Ping, Schatz, Michael C., Street, Craig, Zhao, Yan, Desany, Brian, ...

Recent steep declines in honey bee health have severely impacted the beekeeping industry, presenting new risks for agricultural commodities that depend on insect pollination. Honey bee declines could...

Gasless laparoscopy for benign gynecological diseases using an abdominal wall-lifting system

Wang, Yue, Cui, Heng, Zhao, Yan, Wang, Zhi-qi

Objectives: The use of gasless laparoscopy with an abdominal wall-lifting device for benign gynecological diseases was compared to conventional laparoscopy with CO2 pneumoperitoneum. Methods: From...

The expression of nr0b1, the earliest gene in zebrafish tooth development, is a marker for human tooth and ameloblastoma formation

Powers, Jamie, Zhao, Yan, Lin, Shuo, McCabe, Edward R. B.

Zebrafish teeth develop on pharyngeal jaws in the 5th branchial arch, but early tooth development is remarkably similar to mammals (Borday-Birraux et al., Evol Dev 8:130, 2006). Recently, eve1 has...