Yang Shen

Energy Audit and Accounting for Riksbyggen Fastighetsservice, Gävle (2009)

Liu, Yuanyuan, Shen, Yang

Riksbyggen Fastighetsservice is a company whose businesses cope with building construction and related services. The local office of Riksbyggen Fastighetsservice in Gävle has been studied in this...

Evolution under canalization and the dual roles of microRNAs--A hypothesis (2009)

Wu, Chung-I, Shen, Yang, Tang, Tian

Canalization refers to the process by which phenotypes are stabilized within species. Evolution by natural selection can proceed efficiently only when phenotypes are canalized. The existence and...

Energy Audit and Accounting for Riksbyggen Fastighetsservice, Gävle (2009)

Liu, Yuanyuan, Shen, Yang

Riksbyggen Fastighetsservice is a company whose businesses cope with building construction and related services. The local office of Riksbyggen Fastighetsservice in Gävle has been studied in this...

ADVISORS (2008)

Peter Cornillon, Kathy Donohue, Brian Heikes, Katie Kelley, Roger P. Kelly, John King, ...

This report presents the papers written by the 11 participants in the 2006 Summer Undergraduate

ADVISORS (2008)

Bob Campbell, Steve Carey, Peter Cornillon, Chris Kincaid, John King, ...

This report presents the papers written by the 13 participants in the 2003 Summer Undergraduate

ADVISORS (2008)

Jeremy Collie, Isaac Ginis, Alfred Hanson, John Merrill, Robert Pockalny, Tom Rossby, ...

This report presents the papers written by the 11 participants in the 2004 Summer Undergraduate

Protein Docking by the Underestimation of Free Energy Funnels in the Space of Encounter Complexes (2008)

Shen, Yang, Paschalidis, Ioannis Ch., Vakili, Pirooz, Vajda, Sandor

Similarly to protein folding, the association of two proteins is driven by a free energy funnel, determined by favorable interactions in some neighborhood of the native state. We describe a docking...

23 Visual Guided Approach-to-grasp for Humanoid Robots (2008)

Yang Shen, De Xu, Min Tan, Ze-min Jiang

Vision based control for robots has been an active area of research for more than 30 years and significant progresses in the theory and application have been reported (Hutchinson et al., 1996; Kragic...

Adaptive Evolution of Newly Emerged Micro-RNA Genes in Drosophila (2008)

Lu, Jian, Fu, Yonggui, Kumar, Supriya, Shen, Yang, Zeng, Kai, Xu, Anlong, ...

How often micro-RNA (miRNA) genes emerged and how fast they evolved soon after their emergence are some of the central questions in the evolution of miRNAs. Because most known miRNA genes are ancient...

Phase Velocities of Rayleigh Waves in the MELT Experiment on the East Pacific Rise (2007)

K. G. Dueker, A. F. Sheehan, J. Geophys Res, A. Li, K. M. Fisher, M. E. Wysession, ...

Because it is unlikely that the mantle transition zone is thicker (colder) than normal beneath all the geological

Building native protein conformation from NMR backbone chemical shifts using Monte Carlo fragment assembly (2007)

Gong, Haipeng, Shen, Yang, Rose, George D.

We have been analyzing the extent to which protein secondary structure determines protein tertiary structure in simple protein folds. An earlier paper demonstrated that three-dimensional structure...

Tuning Compiler Optimization Options via Simulated Annealing (2007)

Shen, Yang

To find a good set of options for a particular CPU and particular software is actually a difficult task. Some tool based on genetic algorithm like AcovEA exists, it will compile and run each program...

Genomic Variation in Rice: Genesis of Highly Polymorphic Linkage Blocks during Domestication (2006)

Tian Tang, Jian Lu, Jianzi Huang, Jinghong He, Susan R. McCouch, Yang Shen, ...

Genomic regions that are unusually divergent between closely related species or racial groups can be particularly informative about the process of speciation or the operation of natural selection....

Structural and mechanistic studies on the biotin carboxylase and the carboxyltransferase of acetyl-coenzyme A carboxylase (2006)

Shen, Yang

Acetyl-CoA carboxylase (ACC) catalyzes the rate-limiting reaction in de novo fatty acid biosynthesis, which proceeds in two steps catalyzed by the biotin carboxylase (BC) and carboxyltransferase...

Precise and accurate structural genomics protein structure determination using RD and GFT NMR spectroscopy [electronic resource] / (2006)

Shen, Yang.

Summary: Nuclear magnetic resonance (NMR) has emerged as a powerful tool for determining three-dimensional structures of proteins in solution. The major part of this dissertation describes the...

Prediction of peptide maps in CZE and MEKC systems (2005)

Shen, Yang

A new Quantitative Structure-Migration Relationships(QSMR) model was developed to predict the electrophoretic mobilities of peptides in capillary zone electrophoresis(CZE). A three-step strategy was...

Prediction of peptide maps in CZE and MEKC systems (2005)

Shen, Yang.

Thesis (M.S.)--North Carolina State University.

The NMR solution structure of the 30S ribosomal protein S27e encoded in gene RS27_ARCFU of Archaeoglobus fulgidis reveals a novel protein fold (2004)

Herve Du Penhoat, Catherine, Atreya, Hanudatta S., Shen, Yang, Liu, Gaohua, Acton, Thomas B., Xiao, Rong, ...

The Archaeoglobus fulgidis gene RS27_ARCFU encodes the 30S ribosomal protein S27e. Here, we present the high-quality NMR solution structure of this archaeal protein, which comprises a C4 zinc finger...

Mantle flow and melt generation beneath mid-ocean ridges / (1995)

Shen, Yang.

Available in film copy from University Microfilms International.

Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain

Jogl, Gerwald, Shen, Yang, Gebauer, Damara, Li, Jiang, Wiegmann, Katja, Kashkar, Hamid, ...

The BEACH domain is highly conserved in a large family of eukaryotic proteins, and is crucial for their functions in vesicle trafficking, membrane dynamics and receptor signaling. However, it does...

All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia

Shen, Zhi-Xiang, Shi, Zhan-Zhong, Fang, Jing, Gu, Bai-Wei, Li, Jun-Min, Zhu, Yong-Mei, ...

Both all-trans retinoic acid (ATRA) and arsenic trioxide (As2O3) have proven to be very effective in obtaining high clinical complete remission (CR) rates in acute promyelocytic leukemia (APL), but...

Redundant Roles for Met Docking Site Tyrosines and the Gab1 Pleckstrin Homology Domain in InlB-Mediated Entry of Listeria monocytogenes

Basar, Tumay, Shen, Yang, Ireton, Keith

The bacterial pathogen Listeria monocytogenes causes food-borne illnesses leading to gastroenteritis, meningitis, or abortion. Listeria induces its internalization into some mammalian cells through...

NMR data collection and analysis protocol for high-throughput protein structure determination

Liu, Gaohua, Shen, Yang, Atreya, Hanudatta S., Parish, David, Shao, Ying, Sukumaran, Dinesh K., ...

A standardized protocol enabling rapid NMR data collection for high-quality protein structure determination is presented that allows one to capitalize on high spectrometer sensitivity: a set of five...

Genomic Variation in Rice: Genesis of Highly Polymorphic Linkage Blocks during Domestication

Tang, Tian, Lu, Jian, Huang, Jianzi, He, Jinghong, McCouch, Susan R, Shen, Yang, ...

Genomic regions that are unusually divergent between closely related species or racial groups can be particularly informative about the process of speciation or the operation of natural selection....

Refined mapping of the gene causing familial mediterranean fever, by linkage and homozygosity studies

Aksentijevich, Ivona, Pras, Elon, Gruberg, Luis, Shen, Yang, Holman, Katherine, Helling, Sharon, ...

Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by attacks of fever and serosal inflammation; the biochemical basis is unknown. We recently reported linkage of the...

Familial mediterranean fever (FMF) in Moroccan Jews: Demonstration of a founder effect by extended haplotype analysis

Aksentijevich, Ivona, Pras, Elon, Gruberg, Luis, Shen, Yang, Holman, Katherine, Helling, Sharon, ...

Familial Mediterranean fever (FMF) is an autosomal recessive disease causing attacks of fever and serositis. The FMF gene (designated “MEF”) is on 16p, with the gene order...

Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain

Jogl, Gerwald, Shen, Yang, Gebauer, Damara, Li, Jiang, Wiegmann, Katja, Kashkar, Hamid, ...

The BEACH domain is highly conserved in a large family of eukaryotic proteins, and is crucial for their functions in vesicle trafficking, membrane dynamics and receptor signaling. However, it does...

All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia

Shen, Zhi-Xiang, Shi, Zhan-Zhong, Fang, Jing, Gu, Bai-Wei, Li, Jun-Min, Zhu, Yong-Mei, ...

Both all-trans retinoic acid (ATRA) and arsenic trioxide (As2O3) have proven to be very effective in obtaining high clinical complete remission (CR) rates in acute promyelocytic leukemia (APL), but...

Redundant Roles for Met Docking Site Tyrosines and the Gab1 Pleckstrin Homology Domain in InlB-Mediated Entry of Listeria monocytogenes

Basar, Tumay, Shen, Yang, Ireton, Keith

The bacterial pathogen Listeria monocytogenes causes food-borne illnesses leading to gastroenteritis, meningitis, or abortion. Listeria induces its internalization into some mammalian cells through...

NMR data collection and analysis protocol for high-throughput protein structure determination

Liu, Gaohua, Shen, Yang, Atreya, Hanudatta S., Parish, David, Shao, Ying, Sukumaran, Dinesh K., ...

A standardized protocol enabling rapid NMR data collection for high-quality protein structure determination is presented that allows one to capitalize on high spectrometer sensitivity: a set of five...

Genomic Variation in Rice: Genesis of Highly Polymorphic Linkage Blocks during Domestication

Tang, Tian, Lu, Jian, Huang, Jianzi, He, Jinghong, McCouch, Susan R, Shen, Yang, ...

Genomic regions that are unusually divergent between closely related species or racial groups can be particularly informative about the process of speciation or the operation of natural selection....

Refined mapping of the gene causing familial mediterranean fever, by linkage and homozygosity studies

Aksentijevich, Ivona, Pras, Elon, Gruberg, Luis, Shen, Yang, Holman, Katherine, Helling, Sharon, ...

Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by attacks of fever and serosal inflammation; the biochemical basis is unknown. We recently reported linkage of the...

Familial mediterranean fever (FMF) in Moroccan Jews: Demonstration of a founder effect by extended haplotype analysis

Aksentijevich, Ivona, Pras, Elon, Gruberg, Luis, Shen, Yang, Holman, Katherine, Helling, Sharon, ...

Familial Mediterranean fever (FMF) is an autosomal recessive disease causing attacks of fever and serositis. The FMF gene (designated “MEF”) is on 16p, with the gene order...

Calmodulin interacts with the platelet ADP receptor P2Y1

Arthur, Jane F., Shen, Yang, Mu, Fi-Tjen, Leon, Catherine, Gachet, Christian, Berndt, Michael C., ...

P2Y1 [P2 (purinergic type-2)-receptor 1] is a G-protein-coupled ADP receptor that regulates platelet activation and ADP-induced Ca2+ signalling. Studies using P2Y1-knockout mice, Gq-deficient mice or...

The NMR solution structure of the 30S ribosomal protein S27e encoded in gene RS27_ARCFU of Archaeoglobus fulgidis reveals a novel protein fold

Herve Du Penhoat, Catherine, Atreya, Hanudatta S., Shen, Yang, Liu, Gaohua, Acton, Thomas B., Xiao, Rong, ...

The Archaeoglobus fulgidis gene RS27_ARCFU encodes the 30S ribosomal protein S27e. Here, we present the high-quality NMR solution structure of this archaeal protein, which comprises a C4 zinc finger...

Building native protein conformation from NMR backbone chemical shifts using Monte Carlo fragment assembly

Gong, Haipeng, Shen, Yang, Rose, George D.

We have been analyzing the extent to which protein secondary structure determines protein tertiary structure in simple protein folds. An earlier paper demonstrated that three-dimensional structure...

Consistent blind protein structure generation from NMR chemical shift data

Shen, Yang, Lange, Oliver, Delaglio, Frank, Rossi, Paolo, Aramini, James M., Liu, Gaohua, ...

Protein NMR chemical shifts are highly sensitive to local structure. A robust protocol is described that exploits this relation for de novo protein structure generation, using as input experimental...

Protein Docking by the Underestimation of Free Energy Funnels in the Space of Encounter Complexes

Shen, Yang, Paschalidis, Ioannis Ch., Vakili, Pirooz, Vajda, Sandor

Similarly to protein folding, the association of two proteins is driven by a free energy funnel, determined by favorable interactions in some neighborhood of the native state. We describe a docking...

Effects of Schisandra sphenanthera extract on the pharmacokinetics of tacrolimus in healthy volunteers

Xin, Hua-Wen, Wu, Xiao-Chun, Li, Qing, Yu, Ai-Rong, Zhu, Min, Shen, Yang, ...

What is already known about this subjectSchisandra sphenanthera extract (SchE) and tacrolimus are often co-administrated in treating renal and liver transplant recipients in China.We discovered...

Simultaneous prediction of protein folding and docking at high resolution

Das, Rhiju, André, Ingemar, Shen, Yang, Wu, Yibing, Lemak, Alexander, Bansal, Sonal, ...

Interleaved dimers and higher order symmetric oligomers are ubiquitous in biology but present a challenge to de novo structure prediction methodology: The structure adopted by a monomer can be...