Yanjie Lu

Publication List Details

Period

2008 - 2009

Number

10

Co-Authors

Downregulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines (2009)

Shan, Hongli, Zhang, Yong, Lu, Yanjie, Zhang, Ying, Pan, Zhenwei, Cai, Benzhi, ...

Aims The present study was designed to decipher molecular mechanisms underlying nicotine's promoting atrial fibrillation (AF) by inducing atrial structural remodelling. Methods and results The...

MicroRNA-1 downregulation by propranolol in a rat model of myocardial infarction: a new mechanism for ischaemic cardioprotection (2009)

Lu, Yanjie, Zhang, Yong, Shan, Hongli, Pan, Zhenwei, Li, Xuelian, Li, Baoxin, ...

Aims The present study was designed to investigate whether the beneficial effects of β-blocker propranolol are related to regulation of microRNA miR-1. Methods and results We demonstrated that...

Control of cardiac excitability by microRNAs (2008)

Yang, Baofeng, Lu, Yanjie, Wang, Zhiguo

Cardiovascular disease is the leading cause of morbidity and mortality in developed countries. The pathological process of the heart is associated with an altered expression profile of genes that are...

The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener

Zhao, Weimin, Zhang, Jing, Lu, Yanjie, Wang, Rui

Hydrogen sulfide (H2S) has been traditionally viewed as a toxic gas. It is also, however, endogenously generated from cysteine metabolism. We attempted to assess the physiological role of H2S in the...

Different mechanisms underlying the stimulation of KCa channels by nitric oxide and carbon monoxide

Wu, Lingyun, Cao, Kun, Lu, Yanjie, Wang, Rui

The molecular mechanisms underlying the effects of nitric oxide (NO) and carbon monoxide (CO), individually and collectively, on large-conductance calcium-activated K+ (KCa) channels were...

The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener

Zhao, Weimin, Zhang, Jing, Lu, Yanjie, Wang, Rui

Hydrogen sulfide (H2S) has been traditionally viewed as a toxic gas. It is also, however, endogenously generated from cysteine metabolism. We attempted to assess the physiological role of H2S in the...

Different mechanisms underlying the stimulation of KCa channels by nitric oxide and carbon monoxide

Wu, Lingyun, Cao, Kun, Lu, Yanjie, Wang, Rui

The molecular mechanisms underlying the effects of nitric oxide (NO) and carbon monoxide (CO), individually and collectively, on large-conductance calcium-activated K+ (KCa) channels were...

Pilocarpine modulates the cellular electrical properties of mammalian hearts by activating a cardiac M3 receptor and a K+ current

Wang, Huizhen, Shi, Hong, Lu, Yanjie, Yang, Baofeng, Wang, Zhiguo

Pilocarpine, a muscarinic acetylcholine receptor (mAChR) agonist, is widely used for treatment of xerostomia and glaucoma. It can also cause many other cellular responses by activating different...

miRNAs at the heart of the matter

Wang, Zhiguo, Luo, Xioabin, Lu, Yanjie, Yang, Baofeng

Cardiovascular disease is among the main causes of morbidity and mortality in developed countries. The pathological process of the heart is associated with altered expression profile of genes that...

A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microRNA interference

Lu, Yanjie, Xiao, Jiening, Lin, Huixian, Bai, Yunlong, Luo, Xiaobin, Wang, Zhiguo, ...

Anti-miRNA antisense inhibitors (AMOs) have demonstrated their utility in miRNA research and potential in miRNA therapy. Here we report a modified AMO approach in which multiple antisense units are...