Hypothalamic involvement in Huntington's disease: an in vivo PET study (2008)
Politis, Marios, Pavese, Nicola, Tai, Yen F., Tabrizi, Sarah J., Barker, Roger A., Piccini, Paola
Recent studies have shown alterations in metabolism, sleep and circadian rhythms as well as in several neuropeptides derived from the hypothalamic–pituitary axis in Huntington's disease patients;...
Microglial activation in presymptomatic Huntington's disease gene carriers (2007)
Tai, Yen F., Pavese, Nicola, Gerhard, Alexander, Tabrizi, Sarah J., Barker, Roger A., Brooks, David J., ...
Microglial activation may play a role in the pathogenesis of Huntington's disease (HD). Using 11C-(R)-PK11195 (PK) positron emission tomography (PET), we investigated microglial activation in HD...