The wisdom of the commons: ensemble tree classifiers for prostate cancer prognosis (2009)
Koziol, James A., Feng, Anne C., Jia, Zhenyu, Wang, Yipeng, Goodison, Seven, McClelland, Michael, ...
Motivation: Classification and regression trees have long been used for cancer diagnosis and prognosis. Nevertheless, instability and variable selection bias, as well as overfitting, are well-known...
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing (2009)
Wang, Yipeng, Martinez-Vicente, Marta, Krüger, Ulrike, Kaushik, Susmita, Wong, Esther, Mandelkow, Eva-Maria, ...
Aggregation and cleavage are two hallmarks of Tau pathology in Alzheimer disease (AD), and abnormal fragmentation of Tau is thought to contribute to the nucleation of Tau paired helical filaments....
Arora, Shilpi, Wang, Yipeng, Jia, Zhenyu, Vardar-Sengul, Saynur, Munawar, Ayla, Doctor, Kutbuddin S, ...
Abstract Background UV irradiation activates the epidermal growth factor receptor, induces Egr1 expression and promotes apoptosis in a variety of cell types. We examined the hypothesis that Egr1...
Wang, Yipeng, Qiu, Guixing, Yu, Bin, Zhang, Jianguo, Li, Jiayi, Weng, Xisheng, ...
Abstract Background In idiopathic scoliosis patients, after anterior spinal fusion and instrumentation, the discs (interspace angle) between the lowest instrumented vertebra (LIV) and the next caudal...
WebArray: an online platform for microarray data analysis (2005)
Xia, Xiaoqin, McClelland, Michael, Wang, Yipeng
Abstract Background Many cutting-edge microarray analysis tools and algorithms, including commonly used limma and affy packages in Bioconductor, need sophisticated knowledge of mathematics,...
Enhanced microarray performance using low complexity representations of the transcriptome (2005)
Rondeau, Gaëlle, McClelland, Michael, Nguyen, Toan, Risques, Rosana, Wang, Yipeng, Judex, Martin, ...
Low abundance mRNAs are more difficult to examine using microarrays than high abundance mRNAs due to the effect of concentration on hybridization kinetics and signal-to-noise ratios. This report...
Pickhardt, Marcus, Gazova, Zuzana, Von Bergen, Martin, Khlistunova, Inna, Wang, Yipeng, Hascher, Antje, ...
High-throughput polyribosome fractionation (2004)
Wang, Yipeng, Ringquist, Steven, Cho, Ann H., Rondeau, Gaelle, Welsh, John
Polyribosome sedimentation velocity centrifugation can be used to identify differential regulation of the translation of mRNAs. However, ultracentrifugation presents practical limitations on the...
School of Medicine.
Jeong, Jin-Yong, Mukhopadhyay, Asish K., Dailidiene, Daiva, Wang, Yipeng, Velapatiño, Billie, Gilman, Robert H., ...
Helicobacter pylori is a human-pathogenic bacterial species that is subdivided geographically, with different genotypes predominating in different parts of the world. Here we test and extend an...
In silico dissection of cell-type-associated patterns of gene expression in prostate cancer
Stuart, Robert O., Wachsman, William, Berry, Charles C., Wang-Rodriguez, Jessica, Wasserman, Linda, Klacansky, Igor, ...
Prostate tumors are complex entities composed of malignant cells mixed and interacting with nonmalignant cells. However, molecular analyses by standard gene expression profiling are limited because...
High-throughput polyribosome fractionation
Wang, Yipeng, Ringquist, Steven, Cho, Ann H., Rondeau, Gaelle, Welsh, John
Polyribosome sedimentation velocity centrifugation can be used to identify differential regulation of the translation of mRNAs. However, ultracentrifugation presents practical limitations on the...
Enhanced microarray performance using low complexity representations of the transcriptome
Rondeau, Gaëlle, McClelland, Michael, Nguyen, Toan, Risques, Rosana, Wang, Yipeng, Judex, Martin, ...
Low abundance mRNAs are more difficult to examine using microarrays than high abundance mRNAs due to the effect of concentration on hybridization kinetics and signal-to-noise ratios. This report...
Survey of Differentially Methylated Promoters in Prostate Cancer Cell Lines1*
Wang, Yipeng, Yu, Qiuju, Cho, Ann H, Rondeau, Gaelle, Welsh, John, Adamson, Eileen, ...
DNA methylation and copy number in the genomes of three immortalized prostate epithelial and five cancer cell lines (LNCaP, PC3, PC3M, PC3M-Pro4, and PC3M-LN4) were compared using a microarray-based...
Jeong, Jin-Yong, Mukhopadhyay, Asish K., Dailidiene, Daiva, Wang, Yipeng, Velapatiño, Billie, Gilman, Robert H., ...
Helicobacter pylori is a human-pathogenic bacterial species that is subdivided geographically, with different genotypes predominating in different parts of the world. Here we test and extend an...
In silico dissection of cell-type-associated patterns of gene expression in prostate cancer
Stuart, Robert O., Wachsman, William, Berry, Charles C., Wang-Rodriguez, Jessica, Wasserman, Linda, Klacansky, Igor, ...
Prostate tumors are complex entities composed of malignant cells mixed and interacting with nonmalignant cells. However, molecular analyses by standard gene expression profiling are limited because...
High-throughput polyribosome fractionation
Wang, Yipeng, Ringquist, Steven, Cho, Ann H., Rondeau, Gaelle, Welsh, John
Polyribosome sedimentation velocity centrifugation can be used to identify differential regulation of the translation of mRNAs. However, ultracentrifugation presents practical limitations on the...
Enhanced microarray performance using low complexity representations of the transcriptome
Rondeau, Gaëlle, McClelland, Michael, Nguyen, Toan, Risques, Rosana, Wang, Yipeng, Judex, Martin, ...
Low abundance mRNAs are more difficult to examine using microarrays than high abundance mRNAs due to the effect of concentration on hybridization kinetics and signal-to-noise ratios. This report...
Survey of Differentially Methylated Promoters in Prostate Cancer Cell Lines1*
Wang, Yipeng, Yu, Qiuju, Cho, Ann H, Rondeau, Gaelle, Welsh, John, Adamson, Eileen, ...
DNA methylation and copy number in the genomes of three immortalized prostate epithelial and five cancer cell lines (LNCaP, PC3, PC3M, PC3M-Pro4, and PC3M-LN4) were compared using a microarray-based...
Interaction between Cell Division Proteins FtsE and FtsZ▿
Corbin, Brian D., Wang, Yipeng, Beuria, Tushar K., Margolin, William
FtsE and FtsX, which are widely conserved homologs of ABC transporters and interact with each other, have important but unknown functions in bacterial cell division. Coimmunoprecipitation of...
Odorranalectin Is a Small Peptide Lectin with Potential for Drug Delivery and Targeting
Li, Jianxu, Wu, Hongbing, Hong, Jing, Xu, Xueqing, Yang, Hailong, Wu, Bingxian, ...
Snake Cathelicidin from Bungarus fasciatus Is a Potent Peptide Antibiotics
Wang, Yipeng, Hong, Jing, Liu, Xiuhong, Yang, Hailong, Liu, Rui, Wu, Jing, ...
Arora, Shilpi, Wang, Yipeng, Jia, Zhenyu, Vardar-Sengul, Saynur, Munawar, Ayla, Doctor, Kutbuddin S, ...
UV stimulation of prostate cells causes an apoptotic response that is dependent on the zinc finger transcription factor Egr1; downstream targets of Egr1 in this response were identified.
Hoemme, Claudia, Peerzada, Abdul, Behre, Gerhard, Wang, Yipeng, McClelland, Michael, Nieselt, Kay, ...
The translocation t(15;17) generates the chimeric PML-RARα transcription factor that is the initiating event of acute promyelocytic leukemia. A global view of PML-RARα transcriptional functions was...