Attempts to Synthesize 3-acyl-4-hydroxycoumarins from Meldrum’s acid -- and Related Chemistry (2007)
Ye, Fengbin, Tropp, Kristin, Yu, Yiting
We start our synthetic work with the acylation of Meldrum’s acid to get three different 5-acyl Meldrum’s acids. These compounds are attacked by various nucleophiles containing different hetero...
Yu, Yiting, Kim, H Stanley, Chua, Hui, Lin, Chi, Sim, Siew, Lin, Daoxun, ...
Abstract Background The Gram-negative bacterium Burkholderia pseudomallei (Bp) is the causative agent of the human disease melioidosis. To understand the evolutionary mechanisms contributing to Bp...
Yu, Yiting, Kim, H. S., Chua, Hui H., Lin, Chi H., Sim, Siew H., Lin, Daoxun, ...
The Gram-negative bacterium Burkholderia pseudomallei (Bp) is the causative agent of the human disease melioidosis. To understand the evolutionary mechanisms contributing to Bp virulence, we...
The Airborne Metagenome in an Indoor Urban Environment
Tringe, Susannah G., Zhang, Tao, Liu, Xuguo, Yu, Yiting, Lee, Wah Heng, Yap, Jennifer, ...
The indoor atmosphere is an ecological unit that impacts on public health. To investigate the composition of organisms in this space, we applied culture-independent approaches to microbes harvested...
The Core and Accessory Genomes of Burkholderia pseudomallei: Implications for Human Melioidosis
Sim, Siew Hoon, Yu, Yiting, Lin, Chi Ho, Karuturi, R. Krishna M., Wuthiekanun, Vanaporn, Tuanyok, Apichai, ...
Natural isolates of Burkholderia pseudomallei (Bp), the causative agent of melioidosis, can exhibit significant ecological flexibility that is likely reflective of a dynamic genome. Using...
Cryopreservation of Neurospheres Derived from Human Glioblastoma Multiforme
Chong, Yuk-Kien, Toh, Tan-Boon, Zaiden, Norazean, Poonepalli, Anuradha, Leong, Siew Hong, Ong, Catherine Ee Ling, ...
Cancer stem cells have been shown to initiate and sustain tumor growth. In many instances, clinical material is limited, compounded by a lack of methods to preserve such cells at convenient time...