Deletion of Ultraconserved Elements Yields Viable Mice (2007)
Nadav Ahituv, Yiwen Zhu, Axel Visel, Amy Holt, Veena Afzal, Len A. Pennacchio, ...
Ultraconserved elements have been suggested to retain extended perfect sequence identity between the human, mouse, and rat genomes due to essential functional properties. To investigate the...
Deletion of ultraconserved elements yields viable mice (2007)
Ahituv, Nadav, Zhu, Yiwen, Visel, Axel, Holt, Amy, Afzal, Veena, Pennacchio, Len A., ...
Ultraconserved elements have been suggested to retain extended perfect sequence identity between the human, mouse, and rat genomes due to essential functional properties. To investigate the...
Megabase deletions of gene deserts result in viable mice (2004)
Nobrega, Marcelo A., Zhu, Yiwen, Plajzer-Frick, Ingrid, Afzal, Veena, Rubin, Edward M.
The functional importance of the approximately 98 percent of mammalian genomes not corresponding to protein coding sequences remain largely un-scrutinized 1. To test experimentally whether some...
Frazer, Kelly A., Ueda, Yukihiko, Zhu, Yiwen, Gifford, Vincent R., Garofalo, Maria R., Mohandas, Narla, ...
Genomic interval engineering of mice identifies a novel modulator of triglyceride production
Zhu, Yiwen, Jong, Miek C., Frazer, Kelly A., Gong, Elaine, Krauss, Ronald M., Cheng, Jan-Fang, ...
To accelerate the biological annotation of novel genes discovered in sequenced regions of mammalian genomes, we are creating large deletions in the mouse genome targeted to include clusters of such...
Genomic interval engineering of mice identifies a novel modulator of triglyceride production
Zhu, Yiwen, Jong, Miek C., Frazer, Kelly A., Gong, Elaine, Krauss, Ronald M., Cheng, Jan-Fang, ...
To accelerate the biological annotation of novel genes discovered in sequenced regions of mammalian genomes, we are creating large deletions in the mouse genome targeted to include clusters of such...
Deletion of Ultraconserved Elements Yields Viable Mice
Ahituv, Nadav, Zhu, Yiwen, Visel, Axel, Holt, Amy, Afzal, Veena, Pennacchio, Len A, ...
Ultraconserved elements have been suggested to retain extended perfect sequence identity between the human, mouse, and rat genomes due to essential functional properties. To investigate the...