Yngve Bergqvist

Low validity of caretakers’ reports on antimalarial and antibiotic use in children with severe pneumonia at hospital in Uganda (2009)

Hildenwall, Helena, Lindkvist, Jenny, Tumwine, James, Bergqvist, Yngve, Pariyo, George, Tomson, Göran, ...

Febrile children in low-income countries receive care from multiple sources, and caretakers’ ability to report drug intake is crucial for appropriate prescription of drugs when reaching health...

A METHOD FOR SCREENING SOME OF THE MOST COMMON ANTIMALARIAL DRUGS OF TODAY (2008)

Römsing, Susanne, Blessborn, Daniel, Bergqvist, Yngve

Malaria is an infectious decease caused by a one-celled parasite called Plasmodium. The most common types are falciparum and vivax malaria where falciparum is the deadliest form of malaria infection....

A METHOD FOR SCREENING SOME OF THE MOST COMMON ANTIMALARIAL DRUGS OF TODAY (2008)

Römsing, Susanne, Blessborn, Daniel, Bergqvist, Yngve

Malaria is an infectious decease caused by a one-celled parasite called Plasmodium. The most common types are falciparum and vivax malaria where falciparum is the deadliest form of malaria infection....

Importance of pre-analytical factors contributing to measurement uncertainty, when determining sulfadoxine and sulfamethoxazole from capillary blood dried on sampling paper. (2008)

Malm, Mikaela, Lindkvist, Jenny, Bergqvist, Yngve

A bioanalytical method is developed and validated for determination of sulfadoxine (SD) and sulfamethoxazole (SM) in 100 µL capillary blood dried on sampling paper (Whatman 31ET Chr). SD and SM are...

Different doses of amodiaquine and chloroquine for treatment of uncomplicated malaria in children in Guinea-Bissau : Implications for future treatment recommendations (2007)

Kofoed, P.E., Ursing, J., Poulsen, A., Rodrigues, A., Bergqvist, Yngve, Aaby, P., ...

The aim of the present study was to compare different doses of chloroquine (CQ) and amodiaquine (AQ) for the treatment of falciparum malaria in children. Children with Plasmodium falciparum...

Development and validation of an automated solid-phase extraction and liquid chromatographic method for determination of lumefantrine in capillary blood on sampling paper. (2007)

Blessborn, Daniel, Römsing, Susanne, Annerberg, Anna, Sundquist, Daniel, Björkman, Anders, Lindegårdh, Niklas, ...

A bioanalytical method for the determination of lumefantrine in 100 µl blood applied onto sampling paper, by solid-phase extraction and liquid chromatography, has been developed and validated....

Determination of Lumefantrine after Capillary Sampling onto Sampling Paper (2007)

Blessborn, Daniel, Römsing, Susanne, Annerberg, Anna, Sundquist, Daniel, Björkman, Anders, Lindegårdh, Niklas, ...

The antimalarial lumefantrine was first synthesised and registered in China and is now commercially available as a coformulated product together with artemether (Coartem®/Riamet®). This combination...

A new approach to evaluate regression models during validation of bioanalytical assays (2006)

Singtoroj, T., Tärning, J., Annerberg, A., Ashton, M., Bergqvist, Yngve, White, N., ...

The quality of bioanalytical data is highly dependent on using an appropriate regression model for calibration curves. Non-weighted linear regression has traditionally been used but is not...

Development and validation of an automated solid phase extraction and liquid chromatographic method for determination of piperaquine in urine (2006)

Tärning, J., Singtoroj, T., Annerberg, A., Ashton, M., Bergqvist, Yngve, White, N., ...

A sensitive and specific bioanalytical method for determination of piperaquine in urine by automated solid-phase extraction (SPE) and liquid chromatography (LC) has been developed and validated....

Concentrations of Chloroquine and Malaria Parasites in Blood in Nigerian Children

Mockenhaupt, Frank P., May, Jürgen, Bergqvist, Yngve, Ademowo, Olusegun G., Olumese, Peter E., Falusi, Adeyinka G., ...

Consumption of chloroquine (CQ) and subtherapeutic drug levels in blood are considered to be widespread in areas where malaria is endemic. A cross-sectional study was performed with 405 Nigerian...

Concentrations of Chloroquine and Malaria Parasites in Blood in Nigerian Children

Mockenhaupt, Frank P., May, Jürgen, Bergqvist, Yngve, Ademowo, Olusegun G., Olumese, Peter E., Falusi, Adeyinka G., ...

Consumption of chloroquine (CQ) and subtherapeutic drug levels in blood are considered to be widespread in areas where malaria is endemic. A cross-sectional study was performed with 405 Nigerian...

Enantioselective pharmacokinetics of mefloquine during long-term intake of the prophylactic dose

Hellgren, Urban, Berggren-Palme, Ingela, Bergqvist, Yngve, Jerling, Markus

Aims To investigate the kinetics of the (+)RS- and (−)SR-enantiomers and the carboxylic acid metabolite (MMQ) of the antimalarial drug mefloquine (MQ) in healthy volunteers.

Determination of chloroquine and its metabolites in urine: a field method based on ion-pair extraction*

Bergqvist, Yngve, Hed, Christer, Funding, Lars, Suther, Ann

A new straightforward photometric method for the assay of the antimalarial drug chloroquine and its metabolites in urine is described. The method involves an ion-pair extraction procedure with...

Chloroquine Is Grossly Overdosed and Overused but Well Tolerated in Guinea-Bissau▿

Ursing, Johan, Kofoed, Poul-Erik, Rodrigues, Amabelia, Bergqvist, Yngve, Rombo, Lars

High chloroquine doses are commonly prescribed in Guinea-Bissau. Double-dose chloroquine has been shown to be more efficacious (92% efficacy) than the standard dose (80% efficacy). However,...