Predicting Consensus Structures for RNA Alignments Via Pseudo-Energy Minimization (2009)
Junilda Spirollari, Kaizhong Zhang, Vivian Bellofatto, Yongkyu Park, Bruce A. Shapiro
Thermodynamic processes with free energy parameters are often used in algorithms that solve the free energy minimization problem to predict secondary structures of single RNA sequences. While results...
Regulation of the catalytic function of topoisomerase II alpha through association with RNA (2008)
Park, Seung-Won, Parrott, Andrew M., Fritz, David T., Park, Yongkyu, Mathews, Michael B., Lee, Chee-Gun
Topoisomerase IIα interacts with numerous nuclear factors, through which it is engaged in diverse nuclear events such as DNA replication, transcription and the formation or maintenance of...
Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures (2007)
Lin, Michael F, Kheradpour, Pouya, Pedersen, Jakob S, Parts, Leopold, Carlson, Joseph W, ...
Sequencing of multiple related species followed by comparative genomics analysis constitutes a powerful approach for the systematic understanding of any genome. Here, we use the genomes of 12...
Local spreading of MSL complexes from roX genes on the Drosophila X chromosome (2003)
Oh, Hyangyee, Park, Yongkyu, Kuroda, Mitzi I.
MSL proteins and noncoding roX RNAs form complexes to up-regulate hundreds of genes on the Drosophila male X chromosome, and make X-linked gene expression equal in males and females. Altering the...
Topology of RbsC, a Membrane Component of the Ribose Transporter, Belonging to the AraH Superfamily
RbsC of Escherichia coli is the hydrophobic membrane component of ribose uptake system classified as the ATP-binding cassette transporter. To understand the structure and function of RbsC, its...
Local spreading of MSL complexes from roX genes on the Drosophila X chromosome
Oh, Hyangyee, Park, Yongkyu, Kuroda, Mitzi I.
MSL proteins and noncoding roX RNAs form complexes to up-regulate hundreds of genes on the Drosophila male X chromosome, and make X-linked gene expression equal in males and females. Altering the...
Topology of RbsC, a Membrane Component of the Ribose Transporter, Belonging to the AraH Superfamily
RbsC of Escherichia coli is the hydrophobic membrane component of ribose uptake system classified as the ATP-binding cassette transporter. To understand the structure and function of RbsC, its...
Local spreading of MSL complexes from roX genes on the Drosophila X chromosome
Oh, Hyangyee, Park, Yongkyu, Kuroda, Mitzi I.
MSL proteins and noncoding roX RNAs form complexes to up-regulate hundreds of genes on the Drosophila male X chromosome, and make X-linked gene expression equal in males and females. Altering the...
Park, Seung-Won, Kang, Yool Ie, Sypula, Joanna G., Choi, Jiyeon, Oh, Hyangyee, Park, Yongkyu
The male-specific lethal (MSL) complex, which includes two noncoding RNA on X (roX)1 and roX2 RNAs, induces histone H4-Lys16 acetylation for twofold hypertranscription of the male X chromosome in...
Park, Seung-Won, Kuroda, Mitzi I., Park, Yongkyu
Despite differences in size and sequence, the two noncoding roX1 and roX2 RNAs are functionally redundant for dosage compensation of the Drosophila melanogaster male X chromosome. Consistent with...
Regulation of the catalytic function of topoisomerase II alpha through association with RNA
Park, Seung-Won, Parrott, Andrew M., Fritz, David T., Park, Yongkyu, Mathews, Michael B., Lee, Chee-Gun
Topoisomerase IIα interacts with numerous nuclear factors, through which it is engaged in diverse nuclear events such as DNA replication, transcription and the formation or maintenance of...