Yoshiaki Kido

Dynamical Casimir Effect for TE and TM Modes in a Resonant Cavity Bisected by a Plasma Sheet (2009)

Naylor, Wade, Matsuki, S., Nishimura, Tomoaki, Kido, Yoshiaki

Parametric photon creation via the dynamical Casimir effect (DCE) is evaluated numerically, in a three-dimensional rectangular resonant cavity bisected by a semiconductor diaphragm (SD), which is...

Pancreatic β Cell Mass Preserved in Heterozygous PDK1 Knockout Mice (2008)

Takeda, Akihiko, Kido, Yoshiaki, Hashimoto, Naoko, Noda, Tetsuo, Kasuga, Masato

We have demonstrated that 3-phosphoinositide-dependent protein kinase 1 (PDK1)contributes to signaling by insulin or insulin-like growth fctor-1 (IGF-1) that isresponsible for the regulation of both...

Reduced Insulin Signaling and Endoplasmic Reticulum Stress Act Synergistically to Deteriorate Pancreatic β Cell Function (2008)

Matsuda, Tomokazu, Kido, Yoshiaki, Uchida, Tohru, Kasuga, Masato

The total pancreatic β cell mass is reduced in individuals with type 2 diabetes. Weanalyzed the islets of leptin receptor-deficient (Lepr-/-) mice, a model animal for type 2diabetes with obesity....

Enhancement of the Mitogenic Effect by Artificial Juxtacrine Stimulation Using Immobilized EGF (1997)

Ito, Yoshihiro, Li, Jing-Song, Takahashi, Takashi, Imanishi, Yukio, Okabayashi, Yoshinori, Kido, Yoshiaki, ...

Mouse epidermal growth factor (EGF) was covalently conjugated with the water-soluble polymer, poly(acrylic acid) (EGF-PAA), or with the water-insoluble polymer, surface-hydrolyzed poly(methyl...

Preserved Pancreatic β-Cell Development and Function in Mice Lacking the Insulin Receptor-Related Receptor

Kitamura, Tadahiro, Kido, Yoshiaki, Nef, Serge, Merenmies, Jussi, Parada, Luis F., Accili, Domenico

Receptors of the insulin/insulinlike growth factor (IGF) family have been implicated in the regulation of pancreatic β-cell growth and insulin secretion. The insulin receptor-related receptor (IRR)...

Defective insulin secretion in pancreatic β cells lacking type 1 IGF receptor

Xuan, Shouhong, Kitamura, Tadahiro, Nakae, Jun, Politi, Katerina, Kido, Yoshiaki, Fisher, Peter E., ...

Defective insulin secretion is a feature of type 2 diabetes that results from inadequate compensatory increase of β cell mass and impaired glucose-dependent insulin release. β cell proliferation...

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth

Kitamura, Tadahiro, Nakae, Jun, Kitamura, Yukari, Kido, Yoshiaki, Biggs, William H., Wright, Christopher V.E., ...

Diabetes is caused by an absolute (type 1) or relative (type 2) deficiency of insulin-producing β cells. The mechanisms governing replication of terminally differentiated β cells and neogenesis...

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2

Kido, Yoshiaki, Burks, Deborah J., Withers, Dominic, Bruning, Jens C., Kahn, C. Ronald, White, Morris F., ...

Type 2 diabetes is characterized by abnormalities of insulin action in muscle, adipose tissue, and liver and by altered β-cell function. To analyze the role of the insulin signaling pathway in these...

PKCλ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic β cells

Hashimoto, Naoko, Kido, Yoshiaki, Uchida, Tohru, Matsuda, Tomokazu, Suzuki, Kazuhisa, Inoue, Hiroshi, ...

Altered regulation of insulin secretion by glucose is characteristic of individuals with type 2 diabetes mellitus, although the mechanisms that underlie this change remain unclear. We have now...

Preserved Pancreatic β-Cell Development and Function in Mice Lacking the Insulin Receptor-Related Receptor

Kitamura, Tadahiro, Kido, Yoshiaki, Nef, Serge, Merenmies, Jussi, Parada, Luis F., Accili, Domenico

Receptors of the insulin/insulinlike growth factor (IGF) family have been implicated in the regulation of pancreatic β-cell growth and insulin secretion. The insulin receptor-related receptor (IRR)...

Defective insulin secretion in pancreatic β cells lacking type 1 IGF receptor

Xuan, Shouhong, Kitamura, Tadahiro, Nakae, Jun, Politi, Katerina, Kido, Yoshiaki, Fisher, Peter E., ...

Defective insulin secretion is a feature of type 2 diabetes that results from inadequate compensatory increase of β cell mass and impaired glucose-dependent insulin release. β cell proliferation...

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth

Kitamura, Tadahiro, Nakae, Jun, Kitamura, Yukari, Kido, Yoshiaki, Biggs, William H., Wright, Christopher V.E., ...

Diabetes is caused by an absolute (type 1) or relative (type 2) deficiency of insulin-producing β cells. The mechanisms governing replication of terminally differentiated β cells and neogenesis...

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2

Kido, Yoshiaki, Burks, Deborah J., Withers, Dominic, Bruning, Jens C., Kahn, C. Ronald, White, Morris F., ...

Type 2 diabetes is characterized by abnormalities of insulin action in muscle, adipose tissue, and liver and by altered β-cell function. To analyze the role of the insulin signaling pathway in these...

PKCλ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic β cells

Hashimoto, Naoko, Kido, Yoshiaki, Uchida, Tohru, Matsuda, Tomokazu, Suzuki, Kazuhisa, Inoue, Hiroshi, ...

Altered regulation of insulin secretion by glucose is characteristic of individuals with type 2 diabetes mellitus, although the mechanisms that underlie this change remain unclear. We have now...

Biphasic Response of Pancreatic β-Cell Mass to Ablation of Tuberous Sclerosis Complex 2 in Mice▿

Shigeyama, Yutaka, Kobayashi, Toshiyuki, Kido, Yoshiaki, Hashimoto, Naoko, Asahara, Shun-ichiro, Matsuda, Tomokazu, ...

Recent studies have demonstrated the importance of insulin or insulin-like growth factor 1 (IGF-1) for regulation of pancreatic β-cell mass. Given the role of tuberous sclerosis complex 2 (TSC2) as...