Takemoto, Koji, Yamamoto, Yutaka, Ueda, Yutaka, Sumita, Yoshihiro, Yoshida, Koichiro, Niki, Yoshihito
Objectives: The aim of this study was to evaluate the efficacy and tissue concentration of AmBisome and Fungizone in murine pulmonary aspergillosis, and to investigate the localization of AmBisome at...
Takemoto, Koji, Yamamoto, Yutaka, Ueda, Yutaka, Sumita, Yoshihiro, Yoshida, Koichiro, Niki, Yoshihito
Objectives: The efficacy of intravenous injections of a liposomal formulation of amphotericin B (AmBisome) and amphotericin B deoxycholate (Fungizone) was evaluated in immunocompetent and temporarily...
Takemoto, Koji, Yamamoto, Yutaka, Ueda, Yutaka, Sumita, Yoshihiro, Yoshida, Koichiro, Niki, Yoshihito
Objectives: The efficacy of intravenous injections of a liposomal formulation of amphotericin B (AmBisome) and amphotericin B deoxycholate (Fungizone) was evaluated in immunocompetent and temporarily...
Miyashita, Naoyuki, Fukano, Hiroshi, Yoshida, Koichiro, Niki, Yoshihito, Matsushima, Toshiharu
Objectives: To investigate the in vitro activity of cethromycin, a new ketolide, against Chlamydia pneumoniae. Methods: The in vitro activity of cethromycin against 20 isolates of C. pneumoniae was...
Miyashita, Naoyuki, Fukano, Hiroshi, Yoshida, Koichiro, Niki, Yoshihito, Matsushima, Toshiharu
Objectives: To investigate the in vitro activity of cethromycin, a new ketolide, against Chlamydia pneumoniae. Methods: The in vitro activity of cethromycin against 20 isolates of C. pneumoniae was...
Miyashita, Naoyuki, Fukano, Hiroshi, Yoshida, Koichiro, Niki, Yoshihito, Matsushima, Toshiharu
Objectives: To investigate the in vitro activity of cethromycin, a new ketolide, against Chlamydia pneumoniae. Methods: The in vitro activity of cethromycin against 20 isolates of C. pneumoniae was...
In vitro activity of telithromycin, a new ketolide, against Chlamydia pneumoniae (2001)
Miyashita, Naoyuki, Fukano, Hiroshi, Niki, Yoshihito, Matsushima, Toshiharu
The in vitro activity of telithromycin, a new ketolide, was compared with those of roxithromycin, azithromycin, clarithromycin and erythromycin A against 20 strains of Chlamydia pneumoniae. The MICs...
Kamberi, Marika, Tsutsumi, Kimiko, Kotegawa, Tsutomu, Kawano, Koichi, Nakamura, Koichi, Niki, Yoshihito, ...
The impact of acidification and alkalinization of urine on the pharmacokinetics of ciprofloxacin was investigated after single 200-mg oral doses were administered to nine healthy male volunteers. In...
Effect of HSR-903, a New Fluoroquinolone, on the Concentration of Theophylline in Serum
Niki, Yoshihito, Watanabe, Shinsuke, Tamada, Sadao, Yoshida, Koichiro, Miyashita, Naoyuki, Nakajima, Masamitu, ...
The effect of HSR-903, a new fluoroquinolone, on the concentration of theophylline in serum in healthy male volunteers was investigated. The concentration of theophylline in serum and the urinary...
In Vitro and In Vivo Activities of Sitafloxacin against Chlamydia spp.
Miyashita, Naoyuki, Niki, Yoshihito, Matsushima, Toshiharu
The in vitro and in vivo antichlamydial activity of sitafloxacin was investigated. The MICs and minimal chlamydiacidal concentrations of sitafloxacin for various species of chlamydia ranged from...
Niki, Yoshihito, Itokawa, Kenichi, Okazaki, Osamu
In vitro and in vivo studies were conducted to investigate the drug interaction between a new quinolone antimicrobial, DU-6859a, and theophylline (TP). The effect of DU-6859a on TP metabolism was...
Kimura, Soichiro, Alba, Jimena, Shiroto, Katsuaki, Sano, Reiko, Niki, Yoshihito, Maesaki, Shigefumi, ...
The aim of this study was to determine the distribution of metallo-β-lactamase-producing Pseudomonas aeruginosa in Japan and to investigate the molecular characteristics of resistance gene cassettes...
Kamberi, Marika, Tsutsumi, Kimiko, Kotegawa, Tsutomu, Kawano, Koichi, Nakamura, Koichi, Niki, Yoshihito, ...
The impact of acidification and alkalinization of urine on the pharmacokinetics of ciprofloxacin was investigated after single 200-mg oral doses were administered to nine healthy male volunteers. In...
Effect of HSR-903, a New Fluoroquinolone, on the Concentration of Theophylline in Serum
Niki, Yoshihito, Watanabe, Shinsuke, Tamada, Sadao, Yoshida, Koichiro, Miyashita, Naoyuki, Nakajima, Masamitu, ...
The effect of HSR-903, a new fluoroquinolone, on the concentration of theophylline in serum in healthy male volunteers was investigated. The concentration of theophylline in serum and the urinary...
In Vitro and In Vivo Activities of Sitafloxacin against Chlamydia spp.
Miyashita, Naoyuki, Niki, Yoshihito, Matsushima, Toshiharu
The in vitro and in vivo antichlamydial activity of sitafloxacin was investigated. The MICs and minimal chlamydiacidal concentrations of sitafloxacin for various species of chlamydia ranged from...
Niki, Yoshihito, Itokawa, Kenichi, Okazaki, Osamu
In vitro and in vivo studies were conducted to investigate the drug interaction between a new quinolone antimicrobial, DU-6859a, and theophylline (TP). The effect of DU-6859a on TP metabolism was...
Kimura, Soichiro, Alba, Jimena, Shiroto, Katsuaki, Sano, Reiko, Niki, Yoshihito, Maesaki, Shigefumi, ...
The aim of this study was to determine the distribution of metallo-β-lactamase-producing Pseudomonas aeruginosa in Japan and to investigate the molecular characteristics of resistance gene cassettes...